indomethacin has been researched along with Cephalgia Syndromes in 34 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Indomethacin-responsive headaches encompass a group of disorders which include a subset of the trigeminal autonomic cephalalgias and other paroxysmal, often precipitated primary headaches." | 8.12 | Etoricoxib and celecoxib sensitive indomethacin-responsive headache disorders. ( Bahra, A; Farag, M, 2022) |
| "Indomethacin-responsive headache syndromes represent a unique group of primary headache disorders characterized by a prompt and often complete response to indomethacin to the exclusion of other nonsteroidal anti-inflammatory drugs and medications usually effective in treating other primary headache disorders." | 4.82 | Indomethacin-responsive headache syndromes. ( Dodick, DW, 2004) |
| "Indomethacin-responsive headaches encompass a group of disorders which include a subset of the trigeminal autonomic cephalalgias and other paroxysmal, often precipitated primary headaches." | 4.12 | Etoricoxib and celecoxib sensitive indomethacin-responsive headache disorders. ( Bahra, A; Farag, M, 2022) |
| " A trial of indomethacin 75 mg/day was advised, which provided complete relief of the headache." | 4.12 | Hemicrania continua secondary to neurogenic paravertebral tumor- a case report. ( Al-Azzawi, O; Heir, GM; Kalladka, M; Khan, J; Kodapala, S; Nainan, MT, 2022) |
| " Diagnostic criteria of HC, according to II Edition of International Classification of Headache Disorders require complete response to indomethacin." | 3.78 | Hemicrania continua in a headache clinic: referral source and diagnostic delay in a series of 22 patients. ( Campos, D; Cortijo, E; Fernández, R; Guerrero, AL; Herrero, S; Mulero, P; Muñoz, I; Pedraza, MI; Peñas, ML; Rojo, E, 2012) |
| "Chronic headaches are defined as headaches occurring more than 15 days per month for several months." | 2.46 | [Diagnosis and therapy of chronic headaches]. ( Jürgens, TP; May, A, 2010) |
| "Hemicrania continua (HC) is a primary chronic headache disorder characterised with a broad range of autonomic symptoms." | 1.62 | [Blepharyplasty as treatment of chronic headache]. ( Helgestad, OKL; Maarouf, AN, 2021) |
| "Hemicrania continua (HC) is a rare chronic headache disorder, typically accompanied by cranial autonomic features and responding to therapeutic doses of indomethacin." | 1.42 | Postoperative hemicrania continua-like headache - a case series. ( Gantenbein, AR; Goadsby, PJ; Riederer, F; Sarikaya, H, 2015) |
| " And the recommended dosage of indomethacin- both test and long-term dosages-is unallowably high." | 1.40 | Hemicrania continua: major shortcomings in the new classification. ( Antonaci, F; Fredriksen, TA; Sjaastad, O, 2014) |
| "Several patients suffering from chronic headache overuse this symptomatic medication in the attempt to control their headache." | 1.33 | Effect of overuse of the antimigraine combination of indomethacin, prochlorperazine and caffeine (IPC) on the disposition of its components in chronic headache patients. ( Bertolini, A; Coccia, CP; Ferrari, A; Gallesi, D; Leone, S; Loi, M; Pasciullo, G; Pinetti, D; Sances, G; Savino, G; Sternieri, E, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 17 (50.00) | 29.6817 |
| 2010's | 13 (38.24) | 24.3611 |
| 2020's | 4 (11.76) | 2.80 |
| Authors | Studies |
|---|---|
| Farag, M | 1 |
| Bahra, A | 1 |
| Bemanalizadeh, M | 1 |
| Baghaei Oskouei, H | 1 |
| Hadizadeh, A | 1 |
| Dakkali, MS | 1 |
| Qahremani, R | 1 |
| Mansouri, V | 1 |
| Maarouf, AN | 1 |
| Helgestad, OKL | 1 |
| Kalladka, M | 1 |
| Al-Azzawi, O | 1 |
| Heir, GM | 1 |
| Kodapala, S | 1 |
| Nainan, MT | 1 |
| Khan, J | 1 |
| Chan, TLH | 1 |
| Becker, WJ | 1 |
| Jog, M | 1 |
| Rozen, TD | 5 |
| Beams, JL | 1 |
| Goadsby, PJ | 3 |
| Fredriksen, TA | 1 |
| Antonaci, F | 2 |
| Sjaastad, O | 1 |
| Benítez-Rivero, S | 1 |
| González-Oria, C | 1 |
| Gómez-Caravaca, T | 1 |
| Bernal Sánchez-Arjona, M | 1 |
| Jiménez-Hernández, MD | 1 |
| Xanders, LB | 1 |
| Ailani, J | 1 |
| Gantenbein, AR | 1 |
| Sarikaya, H | 1 |
| Riederer, F | 1 |
| Pascual, J | 1 |
| González-Mandly, A | 1 |
| Martín, R | 1 |
| Oterino, A | 1 |
| Lambru, G | 1 |
| Castellini, P | 1 |
| Bini, A | 1 |
| Evangelista, A | 1 |
| Manzoni, GC | 1 |
| Torelli, P | 1 |
| Prakash, S | 2 |
| Husain, M | 1 |
| Sureka, DS | 1 |
| Shah, NP | 1 |
| Shah, ND | 2 |
| Rossi, P | 1 |
| Tassorelli, C | 1 |
| Allena, M | 1 |
| Ferrante, E | 1 |
| Lisotto, C | 1 |
| Nappi, G | 1 |
| May, A | 1 |
| Jürgens, TP | 1 |
| Cortijo, E | 1 |
| Guerrero, AL | 1 |
| Herrero, S | 1 |
| Mulero, P | 1 |
| Muñoz, I | 1 |
| Pedraza, MI | 1 |
| Peñas, ML | 1 |
| Rojo, E | 1 |
| Campos, D | 1 |
| Fernández, R | 1 |
| Boes, CJ | 1 |
| Dodick, DW | 2 |
| Evers, S | 2 |
| Sibon, I | 1 |
| Ghorayeb, I | 1 |
| Henry, P | 1 |
| Rogalewski, A | 1 |
| Saito, Y | 1 |
| Seki, A | 1 |
| Kaneko, K | 1 |
| Yokoyama, A | 1 |
| Isawa, K | 1 |
| Ono, K | 1 |
| Ferrari, A | 1 |
| Savino, G | 1 |
| Gallesi, D | 1 |
| Pinetti, D | 1 |
| Bertolini, A | 1 |
| Sances, G | 1 |
| Coccia, CP | 1 |
| Pasciullo, G | 1 |
| Leone, S | 1 |
| Loi, M | 1 |
| Sternieri, E | 1 |
| Purdy, RA | 1 |
| Centonze, V | 1 |
| D'Amico, D | 1 |
| Usai, S | 1 |
| Causarano, V | 1 |
| Bassi, A | 1 |
| Bussone, G | 1 |
| Moorjani, BI | 1 |
| Rothner, AD | 1 |
| Peres, MF | 1 |
| Stiles, MA | 1 |
| Oshinsky, M | 1 |
| Senanayake, B | 1 |
| De Silva, R | 1 |
| Pareja, JA | 1 |
| Vincent, M | 1 |
9 reviews available for indomethacin and Cephalgia Syndromes
| Article | Year |
|---|---|
Paroxysmal hemicrania in children and adolescents: A systematic review.
Topics: Adolescent; Adult; Child; Child, Preschool; Female; Headache Disorders; Humans; Indomethacin; Infant | 2022 |
Diagnose and adios: practical tips for the ongoing evaluation and care of TAC patients taking indomethacin.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Autonomic Nervous System; Chronic Disease; Dose-Response Re | 2015 |
Is there need to search for alternatives to indomethacin for hemicrania continua? Case reports and a review.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Fructose; Headache Disorders; Human | 2009 |
Focus on therapy: hemicrania continua and new daily persistent headache.
Topics: Amines; Analgesics; Celecoxib; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Fructose; Gaba | 2010 |
[Diagnosis and therapy of chronic headaches].
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Brain; Cross-Sectional Studies; Diagnosis, Dif | 2010 |
Hypnic headache: clinical features, pathophysiology, and treatment.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Comorbidity; Female; Headache Disorders; H | 2003 |
Indomethacin-responsive headache syndromes.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Headache Disorders; Human | 2004 |
First Italian case of hypnic headache, with literature review and discussion of nosology.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Headache Disorders; Humans; Indomethacin; Italy; Lithium; M | 2001 |
The hemicrania continua diagnosis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Headache Disorders; Humans; Indomethacin | 2001 |
1 trial available for indomethacin and Cephalgia Syndromes
| Article | Year |
|---|---|
Headaches precipitated by cough, prolonged exercise or sexual activity: a prospective etiological and clinical study.
Topics: Adult; Cerebral Angiography; Cough; Cyclooxygenase Inhibitors; Exercise; Female; Follow-Up Studies; | 2008 |
24 other studies available for indomethacin and Cephalgia Syndromes
| Article | Year |
|---|---|
Etoricoxib and celecoxib sensitive indomethacin-responsive headache disorders.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Etoricoxib; Headache; Headache Disorders; Humans | 2022 |
[Blepharyplasty as treatment of chronic headache].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Headache; Headache Disorders; Humans; Indomethacin; | 2021 |
Hemicrania continua secondary to neurogenic paravertebral tumor- a case report.
Topics: Adult; Female; Headache; Headache Disorders; Humans; Indomethacin; Neoplasms; Trigeminal Autonomic C | 2022 |
Indomethacin-Responsive Idiopathic Red Ear Syndrome: Case Report and Pathophysiology.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Ear; Erythema; Headache D | 2018 |
A case of post-traumatic LASH syndrome responsive to indomethacin and melatonin (a man with a unique triad of indomethacin-responsive trigeminal autonomic cephalalgias).
Topics: Accidents, Traffic; Adult; Anti-Inflammatory Agents, Non-Steroidal; Central Nervous System Depressan | 2015 |
Hemicrania continua--major shortcomings in the new classification or rigid thinking is death to progress.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Headache Disorders; Humans; Indomethacin | 2014 |
Hemicrania continua: major shortcomings in the new classification.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Female; Headache Disorders; Humans; Indomethacin; Male | 2014 |
[Hemicrania continua and paroxysmal hemicrania: clinical and therapeutic characteristics in a series of 23 patients].
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Autonomic Nervous System; Female; Headache Dis | 2014 |
Postoperative hemicrania continua-like headache - a case series.
Topics: Adult; Female; Headache Disorders; Humans; Indomethacin; Male; Middle Aged; Migraine Disorders; Neur | 2015 |
Hemicrania continua evolving from cluster headache responsive to valproic acid.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Depression; Dyspepsia; Female; GABA Agents; Gastritis; Head | 2008 |
Can indomethacin act as a disease modifying agent in hemicrania continua? A supportive clinical case.
Topics: Activities of Daily Living; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Dru | 2009 |
Pure menstrual hemicrania continua: does it exist? A case report.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Female; Headache Disorders; Humans; Indomethacin; Me | 2010 |
Hemicrania continua in a headache clinic: referral source and diagnostic delay in a series of 22 patients.
Topics: Ambulatory Care Facilities; Anti-Inflammatory Agents, Non-Steroidal; Female; Headache Disorders; Hum | 2012 |
LASH syndrome: a third reported case twelve years after the first.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Autonomic Nervous System Diseases; Female; Headache | 2012 |
Indomethacin-responsive TACs (paroxysmal hemicrania, hemicrania continua, and LASH): further proof of a distinct spectrum of headache disorders.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Autonomic Nervous System Diseases; Cluster Headache; | 2013 |
Refining the clinical spectrum of chronic paroxysmal hemicrania: a review of 74 patients.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Child; Chronic Disease; Female; He | 2002 |
Successful treatment of hypnic headache syndrome with acetazolamide.
Topics: Acetazolamide; Aged; Anti-Inflammatory Agents, Non-Steroidal; Carbonic Anhydrase Inhibitors; Diplopi | 2003 |
Symptomatic hemicrania continua after internal carotid artery dissection.
Topics: Adult; Carotid Artery, Internal, Dissection; Headache Disorders; Humans; Indomethacin; Male | 2005 |
[Effect of propranolol on new daily persistent headache].
Topics: Acetaminophen; Administration, Oral; Adolescent; Child; Drug Therapy, Combination; Female; Headache | 2006 |
Effect of overuse of the antimigraine combination of indomethacin, prochlorperazine and caffeine (IPC) on the disposition of its components in chronic headache patients.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antipsychotic Agents; Area Under Curve; Caffeine; Central N | 2006 |
Teaching case: recurrent headache in a child.
Topics: Adrenergic Uptake Inhibitors; Amitriptyline; Anti-Inflammatory Agents, Non-Steroidal; Child; Female; | 2007 |
Indomethacin-responsive headaches in children and adolescents.
Topics: Adolescent; Adult; Child; Child, Preschool; Cluster Headache; Dose-Response Relationship, Drug; Fema | 2001 |
Remitting form of hemicrania continua with seasonal pattern.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Female; Headache Disorders; Humans; Indomethacin; Melatonin | 2001 |
Lunchtime headache.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cluster Headache; Diagnosis, Differential; Headache Disorde | 2001 |