Page last updated: 2024-10-29

indomethacin and Cataract

indomethacin has been researched along with Cataract in 9 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Cataract: Partial or complete opacity on or in the lens or capsule of one or both eyes, impairing vision or causing blindness. The many kinds of cataract are classified by their morphology (size, shape, location) or etiology (cause and time of occurrence). (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
"We investigated the effects of diclofenac sodium and indomethacin on the proliferation of and collagen synthesis by lens epithelial cells (LECs) of human cataracts in culture."3.69Effects of diclofenac sodium and indomethacin on proliferation and collagen synthesis of lens epithelial cells in vitro. ( Fujiwara, T; Nishi, K; Nishi, O; Shirasawa, E, 1995)
" To determine the effect of inhibition of prostaglandin synthesis on UVB-induced cataract formation, animals were given indomethacin intraperitoneally."3.69The role of prostaglandins E2 and F2 alpha in ultraviolet radiation-induced cortical cataracts in vivo. ( Andley, UP; Becker, B; Fritz, C; Morrison, AR, 1996)
"The indomethacin was fully released within 3 weeks in vitro, a release rate of about 14 micrograms/h."1.29Effect of intraocular sustained release of indomethacin on postoperative inflammation and posterior capsule opacification. ( Morita, T; Nishi, K; Nishi, O; Sakanishi, K; Shirasawa, E; Tada, Y, 1996)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19904 (44.44)18.7374
1990's4 (44.44)18.2507
2000's0 (0.00)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zitte, K1
Bonnin, N1
Kémény, JL1
Bacin, F1
Mulliez, A1
Chiambaretta, F1
Sharma, YR1
Cotlier, E1
Mathur, SK1
Satsangi, UK1
Jain, GC1
Nishi, O2
Nishi, K2
Fujiwara, T1
Shirasawa, E2
Andley, UP1
Fritz, C1
Morrison, AR1
Becker, B1
Tetz, MR1
Ries, MW1
Lucas, C1
Stricker, H1
Völcker, HE1
Morita, T1
Tada, Y1
Sakanishi, K1
Franceschetti, AT1
Bernstein, HN1

Reviews

2 reviews available for indomethacin and Cataract

ArticleYear
Inhibition of posterior capsule opacification by an intraocular-lens-bound sustained drug delivery system: an experimental animal study and literature review.
    Journal of cataract and refractive surgery, 1996, Volume: 22, Issue:8

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibiotics, Antineoplastic; Cataract; Cell Divisi

1996
Some iatrogenic ocular diseases from systemically administered drugs.
    International ophthalmology clinics, 1970,Fall, Volume: 10, Issue:3

    Topics: Animals; Cataract; Cats; Chemical Phenomena; Chemistry; Chloramphenicol; Chloroquine; Chlorpromazine

1970

Other Studies

7 other studies available for indomethacin and Cataract

ArticleYear
[DSAEK after failed penetrating keratoplasty].
    Journal francais d'ophtalmologie, 2015, Volume: 38, Issue:1

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Betamethasone; Cataract; Cataract Extractio

2015
Inhibition of lens and cataract aldose reductase by protein-bound anti-rheumatic drugs: salicylate, indomethacin, oxyphenbutazone, sulindac.
    Experimental eye research, 1982, Volume: 35, Issue:1

    Topics: Aged; Aldehyde Reductase; Animals; Anti-Inflammatory Agents; Cataract; Cattle; Humans; Indomethacin;

1982
Effect of antiprostaglandin drugs on human blood--aqueous barrier.
    Indian journal of ophthalmology, 1981, Volume: 29, Issue:2

    Topics: Aged; Aqueous Humor; Aspirin; Cataract; Cataract Extraction; Eye Proteins; Female; Humans; Indometha

1981
Effects of diclofenac sodium and indomethacin on proliferation and collagen synthesis of lens epithelial cells in vitro.
    Journal of cataract and refractive surgery, 1995, Volume: 21, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cataract; Cell Division; Cells, Cultured; Collagen; Cycloox

1995
The role of prostaglandins E2 and F2 alpha in ultraviolet radiation-induced cortical cataracts in vivo.
    Investigative ophthalmology & visual science, 1996, Volume: 37, Issue:8

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Cataract; Ciliary Body; Conjunctiva; Cornea; Cyclooxygenase I

1996
Effect of intraocular sustained release of indomethacin on postoperative inflammation and posterior capsule opacification.
    Journal of cataract and refractive surgery, 1996, Volume: 22 Suppl 1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aqueous Humor; Biocompatible Materials; Cataract;

1996
Fabry disease: ocular manifestations.
    Birth defects original article series, 1976, Volume: 12, Issue:3

    Topics: Adult; Aminoquinolines; Animals; Cataract; Child; Conjunctiva; Corneal Diseases; Corneal Opacity; Di

1976