Page last updated: 2024-10-29

indomethacin and Carotid Stenosis

indomethacin has been researched along with Carotid Stenosis in 3 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Carotid Stenosis: Narrowing or stricture of any part of the CAROTID ARTERIES, most often due to atherosclerotic plaque formation. Ulcerations may form in atherosclerotic plaques and induce THROMBUS formation. Platelet or cholesterol emboli may arise from stenotic carotid lesions and induce a TRANSIENT ISCHEMIC ATTACK; CEREBROVASCULAR ACCIDENT; or temporary blindness (AMAUROSIS FUGAX). (From Adams et al., Principles of Neurology, 6th ed, pp 822-3)

Research Excerpts

ExcerptRelevanceReference
"Pretreatment with indomethacin (2 mg/kg/day) or celecoxib (5 mg/kg/day) post surgery and up to 3 days thereafter did not prevent memory deficits caused by silicone collar implants."1.33Inhibitory avoidance memory retention in the elevated T-maze is impaired after perivascular manipulation of the common carotid arteries. ( Almeida, Sde S; de Aguiar Corrêa, FM; de Bortoli, VC; de Oliveira, AM; Zangrossi Júnior, H, 2005)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Straube, A1
Linn, J1
de Bortoli, VC1
Zangrossi Júnior, H1
de Aguiar Corrêa, FM1
Almeida, Sde S1
de Oliveira, AM1
Institoris, A1
Farkas, E1
Berczi, S1
Sule, Z1
Bari, F1

Other Studies

3 other studies available for indomethacin and Carotid Stenosis

ArticleYear
Unilateral headache attacks and ipsilateral atrophy of the tongue due to neurovascular compression of the hypoglossal nerve.
    Cephalalgia : an international journal of headache, 2008, Volume: 28, Issue:9

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Atrophy; Carotid Stenosis; Headache; Humans; Hypoglossal Ne

2008
Inhibitory avoidance memory retention in the elevated T-maze is impaired after perivascular manipulation of the common carotid arteries.
    Life sciences, 2005, Mar-18, Volume: 76, Issue:18

    Topics: Animals; Avoidance Learning; Carotid Arteries; Carotid Stenosis; Celecoxib; Indomethacin; Male; Maze

2005
Effects of cyclooxygenase (COX) inhibition on memory impairment and hippocampal damage in the early period of cerebral hypoperfusion in rats.
    European journal of pharmacology, 2007, Nov-21, Volume: 574, Issue:1

    Topics: Animals; Astrocytes; Brain Ischemia; Carotid Stenosis; Cyclooxygenase Inhibitors; Disease Models, An

2007