indomethacin has been researched along with Cardiovascular Stroke in 63 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We studied the efficacy of aspirin and indomethacin therapy in relieving the discomfort of postmyocardial infarction pericarditis (PMIP) in two studies: (1) a retrospective evaluation of patients with symptomatic PMIP during a 5-year period and (2) a prospective, randomized, single-blind comparison of aspirin and indomethacin in similar patients." | 9.05 | Therapy of symptomatic pericarditis after myocardial infarction: retrospective and prospective studies of aspirin, indomethacin, prednisone, and spontaneous resolution. ( Alpert, JS; Berman, J; Haffajee, CI, 1981) |
| " Patients with symptomatic pericarditis were treated with indomethacin (group 1, n = 73) or ibuprofen (group 2, n = 49) and those without symptomatic pericarditis received neither drug (group 3, n = 99)." | 8.77 | Myocardial infarct expansion during indomethacin or ibuprofen therapy for symptomatic post infarction pericarditis. Influence of other pharmacologic agents during early remodelling. ( Basualdo, CA; Jugdutt, BI, 1989) |
| "We wished to determine whether enhanced bioavailability of bradykinin (BK) and vasodilatory prostaglandins contribute to renovascular and sodium-handling effects of angiotensin-converting enzyme (ACE) inhibition after myocardial infarction (MI)." | 7.69 | Relative contribution of angiotensin II, bradykinin, and prostaglandins to the renal effects of converting enzyme inhibition in rats after chronic myocardial infarction. ( Deck, CC; Gaballa, MA; Raya, TE, 1996) |
| "We investigated the effect of indomethacin, a widely used nonsteroidal antiinflammatory drug, on the healing of myocardial infarction (MI)." | 7.66 | Indomethacin-induced scar thinning after experimental myocardial infarction. ( Braunwald, E; Brown, EJ; Hale, S; Hammerman, H; Kloner, RA; Schoen, FJ, 1983) |
| "We studied the efficacy of aspirin and indomethacin therapy in relieving the discomfort of postmyocardial infarction pericarditis (PMIP) in two studies: (1) a retrospective evaluation of patients with symptomatic PMIP during a 5-year period and (2) a prospective, randomized, single-blind comparison of aspirin and indomethacin in similar patients." | 5.05 | Therapy of symptomatic pericarditis after myocardial infarction: retrospective and prospective studies of aspirin, indomethacin, prednisone, and spontaneous resolution. ( Alpert, JS; Berman, J; Haffajee, CI, 1981) |
| " Patients with symptomatic pericarditis were treated with indomethacin (group 1, n = 73) or ibuprofen (group 2, n = 49) and those without symptomatic pericarditis received neither drug (group 3, n = 99)." | 4.77 | Myocardial infarct expansion during indomethacin or ibuprofen therapy for symptomatic post infarction pericarditis. Influence of other pharmacologic agents during early remodelling. ( Basualdo, CA; Jugdutt, BI, 1989) |
| "In parallel with experimental research into methods for salvage of ischemic myocardium after acute myocardial infarction (AMI) over the last decade, there has been a growing interest in prostaglandins (PG) and their inhibition by aspirin-like drugs or nonsteroidal anti-inflammatory drugs (NSAID)." | 4.76 | Prostaglandin inhibition and myocardial infarct size. ( Becker, LC; Jugdutt, BI, 1981) |
| " We tested whether pretreatment with the kinin receptor antagonist Hoe 140, the nitric oxide synthase inhibitor NG-nitro-L-arginine methyl ester, or the cyclooxygenase inhibitor indomethacin blocked the effect of ramiprilat on infarct size and reperfusion arrhythmias." | 3.69 | Paracrine systems in the cardioprotective effect of angiotensin-converting enzyme inhibitors on myocardial ischemia/reperfusion injury in rats. ( Carretero, OA; Liu, YH; Sabbath, HN; Sharov, VG; Sigmon, DH; Yang, XP, 1996) |
| "We wished to determine whether enhanced bioavailability of bradykinin (BK) and vasodilatory prostaglandins contribute to renovascular and sodium-handling effects of angiotensin-converting enzyme (ACE) inhibition after myocardial infarction (MI)." | 3.69 | Relative contribution of angiotensin II, bradykinin, and prostaglandins to the renal effects of converting enzyme inhibition in rats after chronic myocardial infarction. ( Deck, CC; Gaballa, MA; Raya, TE, 1996) |
| "Isolated perfused rabbit hearts that have previously been subjected to in vivo left ventricular myocardial infarction respond to N-formylmethionyl-leucyl-phenylalanine (fMLP) or bradykinin (BK) administration with the synthesis of large quantities of eicosanoids." | 3.67 | Exaggerated atrial arachidonate metabolism in rabbit left ventricular myocardial infarction. ( Dunkel, CG; Evers, AS; Needleman, P; Saffitz, JE, 1987) |
| " The administration of intravenous ergonovine did not provoke ST-segment shifts or arrhythmias." | 3.67 | Coronary artery spasm after abrupt withdrawal of nitroglycerin in rabbits. ( Cook, L; Reeves, WC; Whitesell, L; Wood, MA, 1985) |
| "We investigated the effect of indomethacin, a widely used nonsteroidal antiinflammatory drug, on the healing of myocardial infarction (MI)." | 3.66 | Indomethacin-induced scar thinning after experimental myocardial infarction. ( Braunwald, E; Brown, EJ; Hale, S; Hammerman, H; Kloner, RA; Schoen, FJ, 1983) |
| "Four non-steroid anti-inflammatory drugs, sulfinpyrazone, acetylsalicylic acid, sodium salicylate and indomethacin were tested in the acute phase of experimental myocardial infarction in conscious rats." | 3.66 | Effect of non-steroid anti-inflammatory drugs in experimental myocardial infarction in rats. ( Koltai, M; Leprán, I; Szekeres, L, 1981) |
| " The pericardial effusion cleared with short-term therapy with corticosteroids and the prolonged use of indomethacin." | 3.65 | Cardiac tamponade with nonhemorrhagic pericardial fluid complicating Dressler's syndrome. ( Mantle, JA; Rackley, CE; Russell, RO; Tew, FT, 1977) |
| " The dose-response to vasoconstrictors and vasodilators was assessed in small resistance coronary arteries." | 1.35 | Effect of fetal anaemia on myocardial ischaemia-reperfusion injury and coronary vasoreactivity in adult sheep. ( Davis, LE; Giraud, GD; He, GW; Hohimer, AR; Underwood, MJ; Van Winkle, DM; Yang, Q, 2008) |
| " In our experiment acute and/or chronic administration of lithium before prolonged ischemia offered significant myoprotective effects in terms of infarct size reduction and improved cardiac function against ischemia/reperfusion injury." | 1.35 | Preconditioning with acute and chronic lithium administration reduces ischemia/reperfusion injury mediated by cyclooxygenase not nitric oxide synthase pathway in isolated rat heart. ( Bazargan, M; Dehpour, AR; Faghihi, M; Mirershadi, F, 2008) |
| "1." | 1.29 | Dissociation of the anti-ischaemic effects of cloricromene from its anti-platelet activity. ( Cirillo, R; Lidbury, PS; Vane, JR, 1993) |
| "In defibrotide-treated preparations, inhibition of PAF formation was associated with a pronounced stimulation of 6-keto-PGF1 alpha generation, which was particularly marked on reperfusion (from 27." | 1.28 | Production and biologic interactions of prostacyclin and platelet-activating factor in acute myocardial ischemia in the perfused rabbit heart. ( Berti, F; De Angelis, L; Galli, G; Magni, F; Rossoni, G, 1990) |
| "Infarct healing delay by prednisolone is dosage dependent, and smaller infarcts may be more sensitive to its effect." | 1.28 | Effect of prednisolone on myocardial infarct healing: characteristics and comparison with indomethacin. ( Iimura, O; Ishimoto, R; Itoya, M; Miura, T; Shizukuda, Y, 1991) |
| "A 23-year-old male with bronchial asthma developed eosinophilia (eosinophils greater than 2,000/mm3) and was observed at our hospital." | 1.28 | [Acute myocardial injury and repeated angina pectoris-like attacks in a young patient with Churg-Strauss syndrome]. ( Arai, Y; Fukushima, N; Isokane, N; Miyamoto, Y; Sano, Y; Suzuki, N, 1991) |
| "Indomethacin treatment abolished the reduction of infarct size seen with defibrotide alone." | 1.28 | Defibrotide reduces infarct size in a rabbit model of experimental myocardial ischaemia and reperfusion. ( Thiemermann, C; Thomas, GR; Vane, JR, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 36 (57.14) | 18.7374 |
| 1990's | 15 (23.81) | 18.2507 |
| 2000's | 7 (11.11) | 29.6817 |
| 2010's | 5 (7.94) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Masclee, GMC | 1 |
| Straatman, H | 1 |
| Arfè, A | 1 |
| Castellsague, J | 1 |
| Garbe, E | 1 |
| Herings, R | 1 |
| Kollhorst, B | 1 |
| Lucchi, S | 1 |
| Perez-Gutthann, S | 1 |
| Romio, S | 1 |
| Schade, R | 1 |
| Schink, T | 1 |
| Schuemie, MJ | 1 |
| Scotti, L | 1 |
| Varas-Lorenzo, C | 1 |
| Valkhoff, VE | 1 |
| Villa, M | 1 |
| Sturkenboom, MCJM | 1 |
| Jiao, Q | 1 |
| Ke, Q | 1 |
| Li, W | 1 |
| Jin, M | 1 |
| Luo, Y | 1 |
| Zhang, L | 1 |
| Yang, D | 1 |
| Zhang, X | 1 |
| Uehara, Y | 1 |
| Murata, Y | 1 |
| Shiga, S | 1 |
| Hosoi, Y | 1 |
| Eren, O | 1 |
| Straube, A | 1 |
| Schöberl, F | 1 |
| Schankin, C | 1 |
| Yang, Q | 1 |
| Hohimer, AR | 1 |
| Giraud, GD | 1 |
| Van Winkle, DM | 1 |
| Underwood, MJ | 1 |
| He, GW | 1 |
| Davis, LE | 1 |
| Faghihi, M | 1 |
| Mirershadi, F | 1 |
| Dehpour, AR | 1 |
| Bazargan, M | 1 |
| Akyel, A | 1 |
| Murat, SN | 1 |
| Cay, S | 1 |
| Kurtul, A | 1 |
| Ocek, AH | 1 |
| Cankurt, T | 1 |
| Gres, P | 1 |
| Schulz, R | 2 |
| Jansen, J | 1 |
| Umschlag, C | 1 |
| Heusch, G | 2 |
| Ralay Ranaivo, H | 1 |
| Diebolt, M | 1 |
| Schott, C | 1 |
| Andriantsitohaina, R | 1 |
| Wen, Q | 1 |
| Sim, MK | 1 |
| Tang, FR | 1 |
| Pereira, RB | 1 |
| Sartório, CL | 1 |
| Vassallo, DV | 1 |
| Stefanon, I | 1 |
| Jiang, X | 1 |
| Shi, E | 1 |
| Nakajima, Y | 1 |
| Sato, S | 1 |
| Ohno, K | 1 |
| Yue, H | 1 |
| Ogawa, K | 3 |
| Enomoto, I | 3 |
| Ito, T | 2 |
| Ban, M | 1 |
| Hashimoto, H | 3 |
| Sakai, K | 2 |
| Mullane, KM | 2 |
| Read, N | 1 |
| Salmon, JA | 1 |
| Moncada, S | 2 |
| Vesterqvist, O | 1 |
| Gréen, K | 1 |
| Hammerman, H | 3 |
| Schoen, FJ | 3 |
| Braunwald, E | 3 |
| Kloner, RA | 3 |
| Brown, EJ | 2 |
| Hale, S | 1 |
| Kai, I | 2 |
| Satake, T | 2 |
| Jugdutt, BI | 3 |
| Becker, LC | 2 |
| Mayrhofer, EF | 1 |
| Feilhauer, GD | 1 |
| Pilecky, I | 1 |
| Vockner, H | 1 |
| Kühn, P | 1 |
| Boelaert, J | 1 |
| Schurgers, M | 1 |
| Daneels, R | 1 |
| Lijnen, P | 2 |
| Amery, A | 1 |
| Hale, SL | 1 |
| Leprán, I | 1 |
| Koltai, M | 1 |
| Szekeres, L | 1 |
| Berman, J | 1 |
| Haffajee, CI | 1 |
| Alpert, JS | 1 |
| Ito, I | 1 |
| Sellke, FW | 1 |
| Wang, SY | 1 |
| Friedman, M | 1 |
| Harada, K | 1 |
| Edelman, ER | 1 |
| Grossman, W | 1 |
| Simons, M | 1 |
| Lidbury, PS | 1 |
| Cirillo, R | 1 |
| Vane, JR | 2 |
| Hohlfeld, T | 1 |
| Strobach, H | 1 |
| Schrör, K | 1 |
| Liu, YH | 1 |
| Yang, XP | 1 |
| Sharov, VG | 1 |
| Sigmon, DH | 1 |
| Sabbath, HN | 1 |
| Carretero, OA | 1 |
| Sulpice, T | 1 |
| Boucher, F | 1 |
| de Leiris, J | 1 |
| Frimm, Cde C | 1 |
| Sun, Y | 1 |
| Weber, KT | 1 |
| Deck, CC | 1 |
| Gaballa, MA | 1 |
| Raya, TE | 1 |
| Bharani, A | 1 |
| Malhotra, A | 1 |
| Talwar, KK | 1 |
| Node, K | 1 |
| Kitakaze, M | 1 |
| Kosaka, H | 1 |
| Minamino, T | 1 |
| Funaya, H | 1 |
| Hori, M | 1 |
| Jalowy, A | 1 |
| Dörge, H | 1 |
| Behrends, M | 1 |
| Aitchison, KA | 1 |
| Coker, SJ | 1 |
| Iliodromitis, EK | 1 |
| Karavolias, GK | 1 |
| Bofilis, E | 1 |
| Yellon, DM | 1 |
| Kremastinos, DT | 1 |
| Kostka-Trabka, E | 1 |
| Hutchins, GM | 1 |
| Bulkley, BH | 1 |
| Pitt, B | 1 |
| Szczeklik, A | 1 |
| Gryglewski, RJ | 1 |
| Musiał, J | 1 |
| Grodzińska, L | 1 |
| Serwońska, M | 1 |
| Marcinkiewicz, E | 1 |
| Tew, FT | 1 |
| Mantle, JA | 1 |
| Russell, RO | 1 |
| Rackley, CE | 1 |
| Cohen, SI | 1 |
| Weintraub, RM | 1 |
| Berti, F | 1 |
| Magni, F | 1 |
| Rossoni, G | 1 |
| De Angelis, L | 1 |
| Galli, G | 1 |
| Shizukuda, Y | 1 |
| Miura, T | 1 |
| Ishimoto, R | 1 |
| Itoya, M | 1 |
| Iimura, O | 1 |
| Suzuki, N | 1 |
| Arai, Y | 1 |
| Miyamoto, Y | 1 |
| Isokane, N | 1 |
| Fukushima, N | 1 |
| Sano, Y | 1 |
| Basualdo, CA | 1 |
| Thiemermann, C | 1 |
| Thomas, GR | 1 |
| Holman, RT | 1 |
| Hess, ML | 1 |
| Rowe, GT | 1 |
| Caplan, M | 1 |
| Romson, JL | 1 |
| Lucchesi, B | 1 |
| Evers, AS | 1 |
| Dunkel, CG | 1 |
| Saffitz, JE | 1 |
| Needleman, P | 1 |
| Klarlund, K | 1 |
| Pedersen, BK | 1 |
| Theander, TG | 1 |
| Andersen, V | 1 |
| Silverman, HS | 1 |
| Pfeifer, MP | 1 |
| Reeves, WC | 1 |
| Cook, L | 1 |
| Wood, MA | 1 |
| Whitesell, L | 1 |
| Sanz, ML | 1 |
| Godfrey, C | 1 |
| Degeorges, M | 1 |
| Passa, P | 1 |
| Varin, G | 1 |
| Delaveirre, PH | 1 |
| Hureau, J | 1 |
| Grivaux, M | 1 |
| Chretien, J | 1 |
| Etienne, JP | 1 |
| Gormsen, J | 1 |
| Andersen, LA | 1 |
| Walker, BA | 1 |
| Lewis, D | 1 |
| Rees, AJ | 1 |
| Kobayakawa, T | 1 |
| Golding, D | 1 |
| Storey, GO | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Vasopressin, Epinephrine, and Corticosteroids for Inhospital Cardiac Arrest: A Multicenter Randomized Controlled Trial[NCT00729794] | Phase 3 | 300 participants (Actual) | Interventional | 2008-09-30 | Completed | ||
| Effect of High Omega-3 Fish Intake on Lipid Peroxidation[NCT01183520] | 30 participants (Actual) | Interventional | 2010-09-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for indomethacin and Cardiovascular Stroke
| Article | Year |
|---|---|
Prostaglandin inhibition and myocardial infarct size.
Topics: Acute Disease; Animals; Aspirin; Coronary Disease; Humans; Ibuprofen; Indomethacin; Models, Biologic | 1981 |
Myocardial infarct expansion during indomethacin or ibuprofen therapy for symptomatic post infarction pericarditis. Influence of other pharmacologic agents during early remodelling.
Topics: Adrenergic alpha-Antagonists; Drug Therapy, Combination; Echocardiography; Ibuprofen; Indomethacin; | 1989 |
Control of polyunsaturated acids in tissue lipids.
Topics: Acrodermatitis; alpha-Linolenic Acid; Arachidonic Acid; Arachidonic Acids; Aspirin; Child; Crohn Dis | 1986 |
1 trial available for indomethacin and Cardiovascular Stroke
| Article | Year |
|---|---|
Therapy of symptomatic pericarditis after myocardial infarction: retrospective and prospective studies of aspirin, indomethacin, prednisone, and spontaneous resolution.
Topics: Adult; Aged; Aspirin; Dextropropoxyphene; Female; Humans; Indomethacin; Male; Middle Aged; Myocardia | 1981 |
59 other studies available for indomethacin and Cardiovascular Stroke
| Article | Year |
|---|---|
Risk of acute myocardial infarction during use of individual NSAIDs: A nested case-control study from the SOS project.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studies; Diclofenac; | 2018 |
Effect of inflammatory factor-induced cyclo-oxygenase expression on the development of reperfusion-related no-reflow phenomenon in acute myocardial infarction.
Topics: Acute Disease; Animals; C-Reactive Protein; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhib | 2015 |
NSAIDs diclofenac, indomethacin, and meloxicam highly upregulate expression of ICAM-1 and COX-2 induced by X-irradiation in human endothelial cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Contraindications; Cyclooxygenase 2; Diclofenac; E-Selectin | 2016 |
Hemicrania Continua: Beneficial Effect of Non-Invasive Vagus Nerve Stimulation in a Patient With a Contraindication for Indomethacin.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Headache Disorders, Primary; Humans; Indomethacin; Male; Mi | 2017 |
Effect of fetal anaemia on myocardial ischaemia-reperfusion injury and coronary vasoreactivity in adult sheep.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Anemia; Animals; Cardiovascular | 2008 |
Preconditioning with acute and chronic lithium administration reduces ischemia/reperfusion injury mediated by cyclooxygenase not nitric oxide synthase pathway in isolated rat heart.
Topics: Animals; Cardiotonic Agents; Cyclooxygenase Inhibitors; Disease Models, Animal; Dose-Response Relati | 2008 |
Late drug eluting stent thrombosis due to acemetacine: type III Kounis syndrome: Kounis syndrome due to acemetacine.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Coronary Angiography; Coronary Thrombosis; Coronary Vessels | 2012 |
Involvement of endogenous prostaglandins in ischemic preconditioning in pigs.
Topics: Analysis of Variance; Animals; Blood Pressure; Cyclooxygenase Inhibitors; Female; Indomethacin; Isch | 2002 |
Polyphenolic compounds from Cognac induce vasorelaxation in vitro and decrease post-ischaemic cardiac infarction after an oral administration.
Topics: Administration, Oral; Alcoholic Beverages; Animals; Aorta, Thoracic; Cyclooxygenase Inhibitors; Flav | 2004 |
Reduction of infarct size by orally administered des-aspartate-angiotensin I in the ischemic reperfused rat heart.
Topics: Administration, Oral; Angiotensin I; Animals; Cardiovascular Agents; Indomethacin; Male; Myocardial | 2004 |
Differences in tail vascular bed reactivity in rats with and without heart failure following myocardial infarction.
Topics: Animals; Dose-Response Relationship, Drug; Heart Failure; Indomethacin; Male; Myocardial Infarction; | 2005 |
Cyclooxygenase-1 mediates the final stage of morphine-induced delayed cardioprotection in concert with cyclooxygenase-2.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Cardiotonic Agents; Cyclooxygenase 1; Cyclooxygenase 2; Cyclo | 2005 |
SG-75 induction of increased coronary outflow and PGE1 from ischemic areas in dogs with experimental myocardial infarction.
Topics: Alprostadil; Animals; Coronary Circulation; Dinoprostone; Dogs; Indomethacin; Lactates; Myocardial I | 1982 |
Role of leukocytes in acute myocardial infarction in anesthetized dogs: relationship to myocardial salvage by anti-inflammatory drugs.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-a | 1984 |
Urinary excretion of 2,3-dinor-thromboxane B2 in man under normal conditions, following drugs and during some pathological conditions.
Topics: Acetaminophen; Adult; Amino Acid Metabolism, Inborn Errors; Aspirin; Circadian Rhythm; Diabetes Mell | 1984 |
Drug-induced expansion of infarct: morphologic and functional correlations.
Topics: Animals; Dogs; Echocardiography; Female; Heart Ventricles; Hydroxyproline; Indomethacin; Male; Myoca | 1984 |
The salvage of ischaemic myocardium by BW755C in anaesthetised dogs.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents; Cor | 1982 |
Indomethacin-induced scar thinning after experimental myocardial infarction.
Topics: Animals; Dogs; Female; Hydroxyproline; Indomethacin; Male; Myocardial Infarction; Myocardium | 1983 |
[Endogenous Prostaglandins in experimental myocardial infarction in canines: the role of released P G E1 and P G F2 alpha in the regulation of coronary blood flow after coronary artery occlusion].
Topics: Animals; Blood Glucose; Coronary Circulation; Coronary Vessels; Dinoprost; Dogs; Indomethacin; Lacta | 1981 |
[Sulfinpyrazone-associated renal failure (author's transl)].
Topics: Acute Kidney Injury; Adult; Aged; Blood Urea Nitrogen; Creatinine; Female; Humans; Indomethacin; Mal | 1982 |
Drug-induced renal failure.
Topics: Humans; Indomethacin; Kidney Failure, Chronic; Myocardial Infarction; Sulfinpyrazone | 1982 |
The effects of early indomethacin administration on late scar formation following myocardial infarction.
Topics: Animals; Dogs; Heart; Indomethacin; Myocardial Infarction; Myocardium | 1982 |
Effect of non-steroid anti-inflammatory drugs in experimental myocardial infarction in rats.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Coronary Vessels; Indomethacin; Male; Myocardial Infarct | 1981 |
Increase of coronary flow and levels of PGE1 and PGF2 alpha from the ischemic area of experimental myocardial infarction.
Topics: Animals; Blood Glucose; Coronary Circulation; Coronary Disease; Dogs; Fatty Acids, Nonesterified; In | 1980 |
Basic FGF enhances endothelium-dependent relaxation of the collateral-perfused coronary microcirculation.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Adenosine Diphosp | 1994 |
Dissociation of the anti-ischaemic effects of cloricromene from its anti-platelet activity.
Topics: Animals; Blood Pressure; Chromonar; Coronary Vessels; Electrocardiography; Heart Rate; Ibuprofen; In | 1993 |
Stimulation of endogenous prostacyclin protects the reperfused pig myocardium from ischemic injury.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Platelets; Cyclooxygenase Inhibitors; Disease Models, A | 1993 |
Paracrine systems in the cardioprotective effect of angiotensin-converting enzyme inhibitors on myocardial ischemia/reperfusion injury in rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine | 1996 |
Limiting lipid peroxidation in the nonischemic zone of infarcted rat hearts by indomethacin improves left ventricular function without affecting myocardial healing and remodeling.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Coronary Vessels; Disease Models, Animal; Indometh | 1996 |
Wound healing following myocardial infarction in the rat: role for bradykinin and prostaglandins.
Topics: Analysis of Variance; Animals; Bradykinin; Bradykinin Receptor Antagonists; Collagen; Coronary Vesse | 1996 |
Relative contribution of angiotensin II, bradykinin, and prostaglandins to the renal effects of converting enzyme inhibition in rats after chronic myocardial infarction.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Bradykinin; Bradykinin Recept | 1996 |
Early post myocardial infarction pericarditis with delayed resolution.
Topics: Adult; Humans; Indomethacin; Male; Myocardial Infarction; Pericarditis; Prednisolone; Time Factors | 1996 |
Amelioration of ischemia- and reperfusion-induced myocardial injury by 17beta-estradiol: role of nitric oxide and calcium-activated potassium channels.
Topics: Animals; Anti-Inflammatory Agents; Calcium; Dogs; Enzyme Inhibitors; Estradiol; Heart Ventricles; In | 1997 |
Infarct size reduction by AT1-receptor blockade through a signal cascade of AT2-receptor activation, bradykinin and prostaglandins in pigs.
Topics: Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Bradykinin; Bradykini | 1998 |
Cyclooxygenase inhibition converts the effect of nitric oxide synthase inhibition from infarct size reduction to expansion in isolated rabbit hearts.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arginine; Cyclic GMP; Cyclooxygenase Inhibitors; Enzyme Inhib | 1999 |
Enhanced protection of heat shock in myocardial infarction: inhibition of detrimental effect of systemic hyperthermia.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Heart Rate; Heat-Shock Response; H | 1999 |
[Protective drug actions in experimental myocardial infarct].
Topics: Adrenergic beta-Antagonists; Animals; Indomethacin; Isoproterenol; Male; Mechlorethamine; Myocardial | 1976 |
Effect of indomethacin on collateral blood flow and infarct size in the conscious dog.
Topics: Animals; Arterial Occlusive Diseases; Collateral Circulation; Coronary Vessels; Dogs; Electrocardiog | 1979 |
Thromboxane generation and platelet aggregation in survivals of myocardial infarction.
Topics: Adult; Aged; Arachidonic Acids; Blood Cell Count; Blood Platelets; Cholesterol; Humans; Indomethacin | 1978 |
Cardiac tamponade with nonhemorrhagic pericardial fluid complicating Dressler's syndrome.
Topics: Adrenal Cortex Hormones; Adult; Cardiac Tamponade; Drainage; Humans; Indomethacin; Male; Myocardial | 1977 |
A new application of counterpulsation: safer laparotomy after recent myocardial infarction.
Topics: Angiography; Assisted Circulation; Blood Pressure; Cardiac Output; Gastrointestinal Hemorrhage; Hemo | 1975 |
Production and biologic interactions of prostacyclin and platelet-activating factor in acute myocardial ischemia in the perfused rabbit heart.
Topics: Animals; Epoprostenol; In Vitro Techniques; Indomethacin; Male; Myocardial Infarction; Myocardium; P | 1990 |
Effect of prednisolone on myocardial infarct healing: characteristics and comparison with indomethacin.
Topics: Animals; Indomethacin; Male; Myocardial Infarction; Myocardium; Prednisolone; Rabbits; Thromboxane B | 1991 |
[Acute myocardial injury and repeated angina pectoris-like attacks in a young patient with Churg-Strauss syndrome].
Topics: Adult; Age Factors; Angina Pectoris; Aspirin; Asthma; Churg-Strauss Syndrome; Eosinophilia; Humans; | 1991 |
Defibrotide reduces infarct size in a rabbit model of experimental myocardial ischaemia and reperfusion.
Topics: Animals; Blood Pressure; Coronary Circulation; Coronary Disease; Electrocardiography; Heart Rate; He | 1989 |
Identification of hydrogen peroxide and hydroxyl radicals as mediators of leukocyte-induced myocardial dysfunction. Limitation of infarct size with neutrophil inhibition and depletion.
Topics: Adenosine Triphosphatases; Animals; Butylated Hydroxytoluene; Calcium; Catalase; Dogs; Free Radicals | 1985 |
Exaggerated atrial arachidonate metabolism in rabbit left ventricular myocardial infarction.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic | 1987 |
Depressed natural killer cell activity in acute myocardial infarction.
Topics: Adult; Aged; Aged, 80 and over; Cytotoxicity, Immunologic; Female; Humans; Indomethacin; Interferon | 1987 |
Relation between use of anti-inflammatory agents and left ventricular free wall rupture during acute myocardial infarction.
Topics: Adrenal Cortex Hormones; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Anti-Inflammatory Agents | 1987 |
[Prostaglandin studies in normal subjects and in post-myocardial infarct patients].
Topics: Adult; Aspirin; Child; Dinoprost; Female; Humans; Indomethacin; Male; Myocardial Infarction; Physica | 1985 |
Coronary artery spasm after abrupt withdrawal of nitroglycerin in rabbits.
Topics: Animals; Arrhythmias, Cardiac; Coronary Vasospasm; Electrocardiography; Ergonovine; Humans; Indometh | 1985 |
Ischemic heart disease: part of the premenstrual syndrome?
Topics: Adult; Angina Pectoris; Female; Humans; Indomethacin; Myocardial Infarction; Premenstrual Syndrome; | 1985 |
[Dressler's syndrome relapsing during corticotherapy but cured with immunosuppressive agents].
Topics: Azathioprine; Humans; Indomethacin; Male; Middle Aged; Myocardial Infarction; Pericarditis; Pleurisy | 1972 |
[Iatrogenic gastroduodenal ulcerations. Corticosteroids excluded].
Topics: Aged; Bone Neoplasms; Carcinoma, Squamous Cell; Cyclophosphamide; Duodenal Ulcer; Female; Humans; In | 1973 |
[Incidence of thrombosis and the status of coagulation in ischaemic heart disease].
Topics: Acute Disease; Aspirin; Blood Coagulation; Chronic Disease; Coronary Disease; Depression, Chemical; | 1974 |
Acute febrile polyarticular gout provoked by myocardial infarction.
Topics: Acute Disease; Electrocardiography; Gout; Humans; Indomethacin; Latex Fixation Tests; Male; Middle A | 1972 |
[Experimental study on drugs for the treatment of myocardial infarction].
Topics: Angiography; Animals; Benzyl Compounds; Body Weight; Carboxylic Acids; Dipyridamole; Disease Models, | 1972 |
Angina and indomethacin.
Topics: Adult; Aged; Angina Pectoris; Electrocardiography; Female; Humans; Indomethacin; Male; Middle Aged; | 1970 |
Xanthomatosis, hyperlipoproteinaemia (type II, Fredrickson), gout, cardiac infarction.
Topics: Adult; Cholesterol; Clofibrate; Gout; Humans; Hyperlipidemias; Indomethacin; Lipoproteins; Male; Myo | 1971 |