indomethacin has been researched along with Cardiovascular Pregnancy Complications in 11 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pregnant women destined to develop pregnancy-induced hypertension (PIH) lose refractoriness to the pressor effects of infused angiotensin II (A-II) several weeks before the onset of hypertension." | 7.66 | Effect of prostaglandin synthetase inhibitors on pressor response to angiotensin II in human pregnancy. ( Everett, RB; Gant, NF; MacDonald, PC; Worley, RJ, 1978) |
| "In gravid women who are destined to develop pregnancy-induced hypertension (PIH), normal pregnancy-associated refractoriness to the pressor effects of administered angiotensin II (A-II) is lost several weeks before the onset of hypertension." | 3.66 | Modification of vascular responsiveness to angiotensin II in pregnant women by intravenously infused 5alpha-dihydroprogesterone. ( Everett, RB; Gant, NF; MacDonald, PC; Worley, RJ, 1978) |
| "Pregnant women destined to develop pregnancy-induced hypertension (PIH) lose refractoriness to the pressor effects of infused angiotensin II (A-II) several weeks before the onset of hypertension." | 3.66 | Effect of prostaglandin synthetase inhibitors on pressor response to angiotensin II in human pregnancy. ( Everett, RB; Gant, NF; MacDonald, PC; Worley, RJ, 1978) |
| "Normal human pregnancy is characterized by vascular refractoriness to AII." | 2.36 | Control of vascular responsiveness during human pregnancy. ( Everett, RB; Gant, NF; MacDonald, PC; Worley, RJ, 1980) |
| "The glomerular lesions of preeclampsia consist of swelling of endothelial cells, interposition of mesangial cells and matrix between the endothelial cells and the glomerular basement membrane, and organization of subendothelial deposits of incompletely characterized material." | 1.27 | Accumulation of several basement membrane proteins in glomeruli of patients with preeclampsia and other hypertensive syndromes of pregnancy. Possible role of renal prostaglandins and fibronectin. ( Bariety, J; Foidart, JB; Foidart, JM; Lambotte, R; Lapiere, CM; Mahieu, PR; Nochy, D; Nusgens, B, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (72.73) | 18.7374 |
| 1990's | 3 (27.27) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gant, NF | 4 |
| Worley, RJ | 4 |
| Everett, RB | 4 |
| MacDonald, PC | 4 |
| Ron-El, R | 1 |
| Caspi, E | 1 |
| Herman, A | 1 |
| Schreyer, P | 1 |
| Algom, M | 1 |
| Schlezinger, Z | 1 |
| Foidart, JM | 1 |
| Nochy, D | 1 |
| Nusgens, B | 1 |
| Foidart, JB | 1 |
| Mahieu, PR | 1 |
| Lapiere, CM | 1 |
| Lambotte, R | 1 |
| Bariety, J | 1 |
| Parks, BR | 1 |
| Douglas, BH | 1 |
| Weaver, MM | 1 |
| Gillespie, JE | 1 |
| Davenport, WD | 1 |
| Rawson, JE | 1 |
| Aloamaka, CP | 1 |
| Ezimokhai, M | 1 |
| Osman, NA | 1 |
| Morrison, J | 1 |
| O'Brien, WF | 1 |
| Krammer, J | 1 |
| O'Leary, TD | 1 |
| Mastrogiannis, DS | 1 |
| Knock, GA | 1 |
| McCarthy, AL | 1 |
| Lowy, C | 1 |
| Poston, L | 1 |
| Chand, S | 1 |
| Ferris, TF | 1 |
| Venuto, RC | 1 |
| Bay, WH | 1 |
2 reviews available for indomethacin and Cardiovascular Pregnancy Complications
| Article | Year |
|---|---|
Control of vascular responsiveness during human pregnancy.
Topics: 20-alpha-Dihydroprogesterone; Angiotensin II; Aspirin; Blood Vessels; Cyclic AMP; Female; Humans; Hy | 1980 |
Vascular reactivity to angiotensin II in human pregnancy.
Topics: Adolescent; Angiotensin II; Animals; Aspirin; Blood Pressure; Blood Volume; Dogs; Female; Haplorhini | 1978 |
1 trial available for indomethacin and Cardiovascular Pregnancy Complications
| Article | Year |
|---|---|
The effect of acetaminophen on prostacyclin production in pregnant women.
Topics: 6-Ketoprostaglandin F1 alpha; Acetaminophen; Adult; Cells, Cultured; Double-Blind Method; Endotheliu | 1993 |
8 other studies available for indomethacin and Cardiovascular Pregnancy Complications
| Article | Year |
|---|---|
Unexpected cardiac pathology in pregnant women treated with beta-adrenergic agents (ritodrine).
Topics: Adult; Cardiomyopathies; Cesarean Section; Dyspnea; Female; Heart Septal Defects, Atrial; Humans; In | 1983 |
Accumulation of several basement membrane proteins in glomeruli of patients with preeclampsia and other hypertensive syndromes of pregnancy. Possible role of renal prostaglandins and fibronectin.
Topics: Basement Membrane; Collagen; Female; Fibrin; Fibronectins; Glycoproteins; Humans; Hypertension; Indo | 1983 |
Effect of indomethacin on desoxycorticosterone acetate-sodium chloride-induced renal lesions in the pregnant rat and her offspring.
Topics: Animals; Desoxycorticosterone; Female; Hypertension; Indomethacin; Kidney; Pregnancy; Pregnancy Comp | 1980 |
The mechanism of relaxation in response to magnesium by the aorta of pregnant rats with salt-induced hypertension.
Topics: Animals; Aorta, Thoracic; Blood Pressure; Endothelium, Vascular; Female; Hypertension; In Vitro Tech | 1995 |
Association of gestational diabetes with abnormal maternal vascular endothelial function.
Topics: Acetylcholine; Arginine; Diabetes, Gestational; Endothelium, Vascular; Enzyme Inhibitors; Female; Hu | 1997 |
Modification of vascular responsiveness to angiotensin II in pregnant women by intravenously infused 5alpha-dihydroprogesterone.
Topics: 20-alpha-Dihydroprogesterone; Angiotensin II; Cyclooxygenase Inhibitors; Drug Resistance; Female; Hu | 1978 |
Effect of prostaglandin synthetase inhibitors on pressor response to angiotensin II in human pregnancy.
Topics: Angiotensin II; Aspirin; Blood Pressure; Cyclooxygenase Inhibitors; Female; Humans; Indomethacin; In | 1978 |
Studies of the uterine circulation in the pregnant rabbit.
Topics: Animals; Blood Pressure; Female; Homeostasis; Hypertension; Hypotension; Indomethacin; Nephrectomy; | 1976 |