indomethacin has been researched along with Cardiomegaly in 12 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We studied the effects of des-Asp-angiotensin I, a nine amino acid peptide, on cardiac hypertrophy caused by coarctation of the abdominal aorta in Sprague-Dawley rats." | 7.70 | Effects of des-Asp-angiotensin I on experimentally-induced cardiac hypertrophy in rats. ( Min, L; Sim, MK, 1998) |
| "There were significant fibrosis and inflammatory infiltration in the myocardium and blood vessels, represented by higher hydroxyproline and collagen volume fraction, and a large amount of inflammatory cells in the tissues of SAD rats." | 3.72 | Inflammation is involved in the organ damage induced by sinoaortic denervation in rats. ( Chen, H; Shu, H; Su, DF; Xie, HH; Yuan, WJ; Zhang, C, 2003) |
| "We studied the effects of des-Asp-angiotensin I, a nine amino acid peptide, on cardiac hypertrophy caused by coarctation of the abdominal aorta in Sprague-Dawley rats." | 3.70 | Effects of des-Asp-angiotensin I on experimentally-induced cardiac hypertrophy in rats. ( Min, L; Sim, MK, 1998) |
| "The reasons for referral were hydrops (2), cardiomegaly (1), polyhydramnios and choroid plexus cyst (1), and polyhydramnios and teratoma of the neck (1)." | 1.30 | Isolated ductal closure in utero diagnosed by fetal echocardiography. ( Cavallé-Garrido, T; Farine, D; Heilbut, M; Leal, SD; Ryan, G; Smallhorn, JF, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (41.67) | 18.7374 |
| 1990's | 4 (33.33) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Olatunji, LA | 1 |
| Soladoye, AO | 1 |
| Zhang, C | 1 |
| Chen, H | 1 |
| Xie, HH | 1 |
| Shu, H | 1 |
| Yuan, WJ | 1 |
| Su, DF | 1 |
| Leal, SD | 1 |
| Cavallé-Garrido, T | 1 |
| Ryan, G | 1 |
| Farine, D | 1 |
| Heilbut, M | 1 |
| Smallhorn, JF | 1 |
| Sim, MK | 1 |
| Min, L | 1 |
| Ritchie, RH | 1 |
| Schiebinger, RJ | 1 |
| LaPointe, MC | 1 |
| Marsh, JD | 1 |
| Goldfarb, M | 1 |
| Abassi, Z | 1 |
| Rosen, S | 1 |
| Shina, A | 1 |
| Brezis, M | 1 |
| Heyman, SN | 1 |
| Eulderink, F | 1 |
| Momma, K | 2 |
| Takao, A | 2 |
| Panzenbeck, MJ | 1 |
| Kaley, G | 1 |
| Calabro, JJ | 1 |
| Katz, RM | 1 |
| Maltz, BA | 1 |
| Limas, CJ | 1 |
| Ragan, D | 1 |
| Freis, ED | 1 |
1 review available for indomethacin and Cardiomegaly
| Article | Year |
|---|---|
A critical reappraisal of juvenile rheumatoid arthritis.
Topics: Agammaglobulinemia; Arthritis, Juvenile; Aspirin; Cardiomegaly; Child; Child, Preschool; Chloroquine | 1971 |
11 other studies available for indomethacin and Cardiomegaly
| Article | Year |
|---|---|
Effects of chronic treatment with cyclooxygenase inhibitor, indomethacin on oral contraceptive-induced high blood pressure in female rats.
Topics: Animals; Blood Pressure; Cardiomegaly; Contraceptives, Oral, Combined; Cyclooxygenase Inhibitors; Et | 2010 |
Inflammation is involved in the organ damage induced by sinoaortic denervation in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Aorta; Blood Vessels; Cardiomegaly; | 2003 |
Isolated ductal closure in utero diagnosed by fetal echocardiography.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cardiomegaly; Choroid Plexus; Cysts; Ductus Arterios | 1997 |
Effects of des-Asp-angiotensin I on experimentally-induced cardiac hypertrophy in rats.
Topics: Angiotensin I; Animals; Blood Pressure; Cardiomegaly; Indomethacin; Rats; Rats, Sprague-Dawley; Rece | 1998 |
Angiotensin II-induced hypertrophy of adult rat cardiomyocytes is blocked by nitric oxide.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Angiotensin II; Animals; Bradyk | 1998 |
Compensated heart failure predisposes to outer medullary tubular injury: studies in rats.
Topics: Acute Kidney Injury; Animals; Cardiomegaly; Cardiovascular Agents; Disease Models, Animal; Enzyme In | 2001 |
[Stiff back and stiff chest. Sectional findings in ankylosing spondylitis].
Topics: Adult; Aminopyrine; Cardiomegaly; Humans; Hypertension, Pulmonary; Indomethacin; Male; Pain; Spine; | 1977 |
Transplacental cardiovascular effects of four popular analgesics in rats.
Topics: Acetaminophen; Analgesics; Animals; Aspirin; Cardiomegaly; Constriction, Pathologic; Ductus Arterios | 1990 |
Right ventricular concentric hypertrophy and left ventricular dilatation by ductal constriction in fetal rats.
Topics: Animals; Cardiomegaly; Constriction, Pathologic; Dilatation, Pathologic; Ductus Arteriosus; Female; | 1989 |
Prostaglandin synthesis inhibition does not normalize baroreflex defects associated with severe right ventricular hypertrophy in conscious dogs.
Topics: Animals; Cardiomegaly; Carotid Arteries; Constriction, Pathologic; Dogs; Heart Rate; Indomethacin; M | 1987 |
Effect of acute cardiac overload on intramyocardial cyclic 3',5'-AMP: relation to prostaglandin synthesis.
Topics: Adenine; Animals; Aorta, Thoracic; Carbon Radioisotopes; Cardiomegaly; Constriction; Cyclic AMP; Dep | 1974 |