indomethacin has been researched along with Carcinoma, Renal Cell in 8 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Carcinoma, Renal Cell: A heterogeneous group of sporadic or hereditary carcinoma derived from cells of the KIDNEYS. There are several subtypes including the clear cells, the papillary, the chromophobe, the collecting duct, the spindle cells (sarcomatoid), or mixed cell-type carcinoma.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Indomethacin treatment was associated with increased expression of glucose-regulated protein 78 (GRP78) and C/EBP homologus protein (CHOP) and activation of ATF-6, characteristics of endoplasmic reticulum stress." | 1.34 | Indomethacin induces apoptosis in 786-O renal cell carcinoma cells by activating mitogen-activated protein kinases and AKT. ( Chen, CJ; Cheng, CL; Hung, YY; Ou, YC; Raung, SL; Yang, CR, 2007) |
| "The bone-resorbing capacity of human renal cell carcinomas in vitro has been examined." | 1.28 | Renal cell carcinoma in tissue culture secretes nondialyzable product that stimulates bone resorption in organ-cultured mouse calvaria. ( Lerner, UH; Ljungberg, B, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 4 (50.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zaki, M | 1 |
| Schöneberg, T | 1 |
| Al Ajrawi, T | 1 |
| Al Said, AN | 1 |
| Sangkuhl, K | 1 |
| Römpler, H | 1 |
| Ou, YC | 1 |
| Yang, CR | 1 |
| Cheng, CL | 1 |
| Raung, SL | 1 |
| Hung, YY | 1 |
| Chen, CJ | 1 |
| Mertens, WC | 1 |
| Bramwell, VH | 1 |
| Banerjee, D | 1 |
| Gwadry-Sridhar, F | 1 |
| al-Mutter, N | 1 |
| Parhar, RS | 1 |
| Lala, PK | 1 |
| Ben-Efraim, S | 1 |
| Tak, C | 1 |
| Fieren, MJ | 1 |
| Romijn, JC | 1 |
| Beckmann, I | 1 |
| Bonta, IL | 1 |
| Yanaihara, H | 1 |
| Nakazono, M | 1 |
| Tsunoda, S | 1 |
| Gregorian, SK | 1 |
| Battisto, JR | 1 |
| Lerner, UH | 1 |
| Ljungberg, B | 1 |
| Chasan, SA | 1 |
| Pothel, LR | 1 |
| Huben, RP | 1 |
1 trial available for indomethacin and Carcinoma, Renal Cell
| Article | Year |
|---|---|
Sustained oral indomethacin and ranitidine with intermittent continuous infusion interleukin-2 in advanced renal cell carcinoma.
Topics: Carcinoma, Renal Cell; Female; Humans; Indomethacin; Interleukin-2; Kidney Neoplasms; Male; Middle A | 1993 |
7 other studies available for indomethacin and Carcinoma, Renal Cell
| Article | Year |
|---|---|
Nephrogenic diabetes insipidus, thiazide treatment and renal cell carcinoma.
Topics: Amino Acid Sequence; Aquaporin 2; Carcinoma, Renal Cell; Cardiovascular Agents; Diabetes Insipidus, | 2006 |
Indomethacin induces apoptosis in 786-O renal cell carcinoma cells by activating mitogen-activated protein kinases and AKT.
Topics: Activating Transcription Factor 6; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; A | 2007 |
Activity of human peritoneal macrophages against a human tumor: role of tumor necrosis factor-alpha, PGE2 and nitrite, in vitro studies.
Topics: Animals; Carcinoma, Renal Cell; Culture Media; Cytotoxicity, Immunologic; Dinoprostone; Humans; Indo | 1993 |
[A case of drug-induced immune hemolytic anemia during alpha-interferon therapy for renal cell carcinoma].
Topics: Anemia, Hemolytic, Autoimmune; Carcinoma, Renal Cell; Diclofenac; Female; Humans; Indomethacin; Inte | 1996 |
Immunosuppression in murine renal cell carcinoma. II. Identification of responsible lymphoid cell phenotypes and examination of elimination of suppression.
Topics: Animals; Antigens, Surface; Carcinoma, Renal Cell; Dinoprostone; Female; Immune Tolerance; Indometha | 1990 |
Renal cell carcinoma in tissue culture secretes nondialyzable product that stimulates bone resorption in organ-cultured mouse calvaria.
Topics: Animals; Bone Matrix; Bone Resorption; Carcinoma, Renal Cell; Culture Media; Cyclooxygenase Inhibito | 1989 |
Management and prognostic significance of hypercalcemia in renal cell carcinoma.
Topics: Calcitonin; Calcium; Carcinoma, Renal Cell; Furosemide; Humans; Hypercalcemia; Indomethacin; Kidney | 1989 |