indomethacin has been researched along with Carcinoma, Medullary in 2 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Carcinoma, Medullary: A carcinoma composed mainly of epithelial elements with little or no stroma. Medullary carcinomas of the breast constitute 5%-7% of all mammary carcinomas; medullary carcinomas of the thyroid comprise 3%-10% of all thyroid malignancies. (From Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1141; Segen, Dictionary of Modern Medicine, 1992)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Indomethacin did not increase apoptosis of TT cells." | 1.35 | Indomethacin inhibits cell growth of medullary thyroid carcinoma by reducing cell cycle progression into S phase. ( Hershman, JM; Moatamed, F; Naeim, F; Sugawara, M; Tomoda, C, 2008) |
| "Medullary thyroid cancer (MTC) is a C cell neoplasm-secreting calcitonin." | 1.32 | Tumor growth inhibition by indomethacin in a mouse model of human medullary thyroid cancer: implication of cyclooxygenases and 15-hydroxyprostaglandin dehydrogenase. ( Cohen, R; Jullienne, A; Lausson, S; Pidoux, E; Quidville, V; Segond, N, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tomoda, C | 1 |
| Moatamed, F | 1 |
| Naeim, F | 1 |
| Hershman, JM | 1 |
| Sugawara, M | 1 |
| Quidville, V | 1 |
| Segond, N | 1 |
| Pidoux, E | 1 |
| Cohen, R | 1 |
| Jullienne, A | 1 |
| Lausson, S | 1 |
2 other studies available for indomethacin and Carcinoma, Medullary
| Article | Year |
|---|---|
Indomethacin inhibits cell growth of medullary thyroid carcinoma by reducing cell cycle progression into S phase.
Topics: Antineoplastic Agents; Apoptosis; Calcitonin; Carcinoembryonic Antigen; Carcinoma, Medullary; Cell C | 2008 |
Tumor growth inhibition by indomethacin in a mouse model of human medullary thyroid cancer: implication of cyclooxygenases and 15-hydroxyprostaglandin dehydrogenase.
Topics: Animals; Apoptosis; Calcitonin; Carcinoma, Medullary; Cell Division; Cyclooxygenase 1; Cyclooxygenas | 2004 |