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indomethacin and Carcinoma, Medullary

indomethacin has been researched along with Carcinoma, Medullary in 2 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Carcinoma, Medullary: A carcinoma composed mainly of epithelial elements with little or no stroma. Medullary carcinomas of the breast constitute 5%-7% of all mammary carcinomas; medullary carcinomas of the thyroid comprise 3%-10% of all thyroid malignancies. (From Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1141; Segen, Dictionary of Modern Medicine, 1992)

Research Excerpts

ExcerptRelevanceReference
"Indomethacin did not increase apoptosis of TT cells."1.35Indomethacin inhibits cell growth of medullary thyroid carcinoma by reducing cell cycle progression into S phase. ( Hershman, JM; Moatamed, F; Naeim, F; Sugawara, M; Tomoda, C, 2008)
"Medullary thyroid cancer (MTC) is a C cell neoplasm-secreting calcitonin."1.32Tumor growth inhibition by indomethacin in a mouse model of human medullary thyroid cancer: implication of cyclooxygenases and 15-hydroxyprostaglandin dehydrogenase. ( Cohen, R; Jullienne, A; Lausson, S; Pidoux, E; Quidville, V; Segond, N, 2004)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tomoda, C1
Moatamed, F1
Naeim, F1
Hershman, JM1
Sugawara, M1
Quidville, V1
Segond, N1
Pidoux, E1
Cohen, R1
Jullienne, A1
Lausson, S1

Other Studies

2 other studies available for indomethacin and Carcinoma, Medullary

ArticleYear
Indomethacin inhibits cell growth of medullary thyroid carcinoma by reducing cell cycle progression into S phase.
    Experimental biology and medicine (Maywood, N.J.), 2008, Volume: 233, Issue:11

    Topics: Antineoplastic Agents; Apoptosis; Calcitonin; Carcinoembryonic Antigen; Carcinoma, Medullary; Cell C

2008
Tumor growth inhibition by indomethacin in a mouse model of human medullary thyroid cancer: implication of cyclooxygenases and 15-hydroxyprostaglandin dehydrogenase.
    Endocrinology, 2004, Volume: 145, Issue:5

    Topics: Animals; Apoptosis; Calcitonin; Carcinoma, Medullary; Cell Division; Cyclooxygenase 1; Cyclooxygenas

2004