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indomethacin and Canine Diseases

indomethacin has been researched along with Canine Diseases in 13 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Research Excerpts

ExcerptRelevanceReference
"Carprofen is a propionic acid-derived NSAID that has anti-inflammatory, analgesic, and antipyretic activity."6.40Use of carprofen for the treatment of pain and inflammation in dogs. ( Fox, SM; Johnston, SA, 1997)
" The direct cytotoxicity of piroxicam indomethacin, and aspirin against 4 canine tumor cell lines (transitional cell carcinoma, squamous cell carcinoma, melanoma, and soft tissue sarcoma) was determined in short-term growth rate assays and in clonogenic assays."3.69Evaluation of in vitro cytotoxicity of nonsteroidal anti-inflammatory drugs against canine tumor cells. ( Chan, TC; Knapp, DW; Kuczek, T; Park, B; Reagan, WJ, 1995)
"Carprofen is a propionic acid-derived NSAID that has anti-inflammatory, analgesic, and antipyretic activity."2.40Use of carprofen for the treatment of pain and inflammation in dogs. ( Fox, SM; Johnston, SA, 1997)
"With indomethacin the swelling was somewhat reduced, but there was no consistent difference to placebo in the pain and limping assessments."1.28Effects of phenylbutazone and indomethacin on the post-operative course following experimental orthopaedic surgery in dogs. ( Løkken, P; Mbugua, SW; Skoglund, LA, 1989)
"Progressive myelopathy in the German shepherd dog is a degenerative neurologic disease of unknown etiology."1.26Progressive myelopathy in older German shepherd dogs. II. Presence of circulating suppressor cells. ( Clemmons, RM; Hinrichs, DJ; Waxman, FJ, 1980)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19905 (38.46)18.7374
1990's7 (53.85)18.2507
2000's1 (7.69)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Amici, C1
Di Caro, A1
Ciucci, A1
Chiappa, L1
Castilletti, C1
Martella, V1
Decaro, N1
Buonavoglia, C1
Capobianchi, MR1
Santoro, MG1
Waxman, FJ1
Clemmons, RM1
Hinrichs, DJ1
Heath, H1
Weller, RE1
Mundy, GR1
Ment, LR1
Stewart, WB1
Duncan, CC1
Scott, DT1
Lambrecht, R1
Knapp, DW1
Chan, TC1
Kuczek, T1
Reagan, WJ1
Park, B1
Collins, JM1
Williams, JF1
Kaiser, L1
Lessard, M1
Yang, WC1
Elliott, GS1
Deslauriers, N1
Brisson, GJ1
Van Vleet, JF1
Schultz, RD1
Fox, SM1
Johnston, SA1
Rainsford, KD1
Skerry, TM1
Chindemi, P1
Delaney, K1
Felsburg, PJ1
HogenEsch, H1
Somberg, RL1
Snyder, PW1
Glickman, LT1
Jones, RD1
Baynes, RE1
Nimitz, CT1
Mbugua, SW1
Skoglund, LA1
Løkken, P1
Ewing, GO1

Reviews

1 review available for indomethacin and Canine Diseases

ArticleYear
Use of carprofen for the treatment of pain and inflammation in dogs.
    Journal of the American Veterinary Medical Association, 1997, May-15, Volume: 210, Issue:10

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin;

1997

Trials

1 trial available for indomethacin and Canine Diseases

ArticleYear
Indomethacin has a potent antiviral activity against SARS coronavirus.
    Antiviral therapy, 2006, Volume: 11, Issue:8

    Topics: Animals; Antiviral Agents; Aspirin; Cell Line; Chlorocebus aethiops; Coronavirus Infections; Coronav

2006

Other Studies

11 other studies available for indomethacin and Canine Diseases

ArticleYear
Progressive myelopathy in older German shepherd dogs. II. Presence of circulating suppressor cells.
    Journal of immunology (Baltimore, Md. : 1950), 1980, Volume: 124, Issue:3

    Topics: Aging; Animals; Cell Adhesion; Cell Separation; Dog Diseases; Dogs; Female; Immunity, Cellular; Incu

1980
Canine lymphosarcoma: a model for study of the hypercalcemia of cancer.
    Calcified tissue international, 1980, Volume: 30, Issue:2

    Topics: Animals; Antineoplastic Agents; Aspirin; Bone Resorption; Calcium; Disease Models, Animal; Dog Disea

1980
Beagle puppy model of intraventricular hemorrhage. Effect of indomethacin on cerebral blood flow.
    Journal of neurosurgery, 1983, Volume: 58, Issue:6

    Topics: Animals; Blood Pressure; Cerebral Hemorrhage; Cerebrovascular Circulation; Disease Models, Animal; D

1983
Evaluation of in vitro cytotoxicity of nonsteroidal anti-inflammatory drugs against canine tumor cells.
    American journal of veterinary research, 1995, Volume: 56, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aspirin; Carcinoma, Squamou

1995
Dirofilaria immitis: heartworm products contract rat trachea in vitro.
    Experimental parasitology, 1994, Volume: 78, Issue:1

    Topics: Acetylcholine; Animals; Aspirin; Culture Techniques; Cyclooxygenase Inhibitors; Dirofilaria immitis;

1994
Suppressive effect of serum from pigs and dogs fed a diet deficient in vitamin E and selenium on lymphocyte proliferation.
    Veterinary research, 1993, Volume: 24, Issue:3

    Topics: 5,8,11,14-Eicosatetraynoic Acid; Animal Feed; Animals; Diethylcarbamazine; Dog Diseases; Dogs; Food,

1993
Effects of the NSAIDs meloxicam and indomethacin on cartilage proteoglycan synthesis and joint responses to calcium pyrophosphate crystals in dogs.
    Veterinary research communications, 1999, Volume: 23, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Calcium Pyrophosphate; Cartilage; Cryst

1999
Immunologic abnormalities in canine juvenile polyarteritis syndrome: a naturally occurring animal model of Kawasaki disease.
    Clinical immunology and immunopathology, 1992, Volume: 65, Issue:2

    Topics: Animals; Aorta; Arthritis, Juvenile; Autoantibodies; Disease Models, Animal; Dog Diseases; Dogs; Imm

1992
Nonsteroidal anti-inflammatory drug toxicosis in dogs and cats: 240 cases (1989-1990)
    Journal of the American Veterinary Medical Association, 1992, Aug-01, Volume: 201, Issue:3

    Topics: Accidents; Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cat Diseases; C

1992
Effects of phenylbutazone and indomethacin on the post-operative course following experimental orthopaedic surgery in dogs.
    Acta veterinaria Scandinavica, 1989, Volume: 30, Issue:1

    Topics: Animals; Dog Diseases; Dogs; Female; Indomethacin; Inflammation; Male; Phenylbutazone; Postoperative

1989
Indomethacin-associated gastrointestinal hemorrhage in a dog.
    Journal of the American Veterinary Medical Association, 1972, Dec-15, Volume: 161, Issue:12

    Topics: Administration, Oral; Animals; Dog Diseases; Dogs; Duodenal Diseases; Female; Gastritis; Gastrointes

1972