indomethacin has been researched along with Cancer of Liver in 39 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (51.28) | 18.7374 |
| 1990's | 7 (17.95) | 18.2507 |
| 2000's | 6 (15.38) | 29.6817 |
| 2010's | 5 (12.82) | 24.3611 |
| 2020's | 1 (2.56) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, Y; Liu, L; Nie, X; Shi, D; Wang, J; Wang, Y; Wei, G; Zhang, L; Zheng, C | 1 |
| Gao, J; Lei, W; Li, S; Liu, H; Peng, X; Wang, S; Yuan, Y; Zhang, J | 1 |
| Chavda, V; Nanavati, P; Patel, S; Savjani, J; Sharma, J | 1 |
| Miao, C; Sun, Z; Wang, Y; Xu, P | 1 |
| Cai, X; Chen, RF; Jiang, ZP; Li, LQ; Li, ZH; Peng, NF; Yang, LQ; Zhou, JJ; Zhou, QB | 1 |
| Cho, CH; Fung, KP; Li, HT; Li, ZJ; Ren, SX; Wong, CC; Wu, WK; Ye, CG; Yeung, JH; Zhang, L | 1 |
| Chen, FY; Yuan, WJ; Zhang, GY | 1 |
| Andriantsitohaina, R; Chasserot, S; Mitolo-Chieppa, D; Potenza, MA; Randriamboavonjy, V; Schneider, F; Stoclet, JC; Tabernero, A; Wolf, P | 1 |
| Gobal, F; Haas, MJ; Horani, MH; Mooradian, AD; Wong, NC | 1 |
| Chang, YC; Joo, ST; Kim, CH; Park, KK; Park, WH | 1 |
| Chadha, N; Dave, P; Fukilman, O; Lee, M; Romeu, J | 1 |
| Mahmud, I; Miura, Y | 1 |
| Buchanan, KD; Cantwell, B; Collins, PG; Fennelly, JJ; Fielding, JF; FitzGerald, O | 1 |
| Meier, J; Metzger, U; Uhlschmid, G; Weihe, H | 1 |
| Bredt, AB; Girey, GJ | 1 |
| Carey, RW; Robinson, DR; Warshaw, AL | 1 |
| Akimoto, T; Jimbo, T; Tohgo, A | 1 |
| Breitman, D; Han, JH; Kasckow, JW; Mulcahey, JJ; Nemeroff, CB; Owens, MJ; Stipetic, MD | 1 |
| Shi, LH | 1 |
| Lohmann, RC; Mertens, WC | 1 |
| Freeman, ML; Gius, D; Guis, D; Harris, S; Holt, JT; Marnett, LJ; Meredith, MJ; Nguyen, TT; Sekhar, KR; Spitz, DR; Summar, ML | 1 |
| de, M; Marinho, R; Pinto, R; Santos, ML | 1 |
| Benvenisti, D; Goldberg, H | 1 |
| Hobara, N; Watanabe, A | 1 |
| Adkison, HW; Baylink, DJ; Marini, BJ; Robertson, RP | 1 |
| Liu, LM; Yu, EX | 1 |
| Agarwal, KC; Tzanakakis, GN; Veronikis, DK; Vezeridis, MP | 1 |
| Ahotupa, M; Bartsch, H; Bereziat, JC; Cabral, JR; Camus, AM; Hietanen, E; Laitinen, M | 1 |
| Itakura, M; Nakase, A; Nohara, T | 1 |
| Banks, M; Gupta, C; Shinozuka, H | 1 |
| Hasumura, Y; Ikeda, T; Takeuchi, J; Tozuka, S | 1 |
| Abe, S | 1 |
| Barcena, R; Boixeda, D; Moreno, A; Saban, J; Serrano-Rios, M | 1 |
| Ibayashi, H; Koga, S; Sakamoto, S; Yokota, M | 1 |
| Aderka, D; Kidron, D; Pinkhas, J; Weinberger, A | 1 |
| Aliño, SF; Hilario, E; Unda, F | 1 |
| Ellison, NM; Servi, RJ | 1 |
| Apps, MC; Cater, DB | 1 |
| Chretien, J; Delaveirre, PH; Etienne, JP; Grivaux, M; Hureau, J | 1 |
2 trial(s) available for indomethacin and Cancer of Liver
| Article | Year |
|---|---|
[Effect of indomethacin on natural killer(NK) cell and T lymphocyte subsets from patients with hepatocellular carcinoma].
Topics: Adjuvants, Immunologic; Adult; Aged; Antimetabolites, Antineoplastic; Carcinoma, Hepatocellular; Female; Humans; Indomethacin; Killer Cells, Natural; Liver Neoplasms; Male; Middle Aged; T-Lymphocyte Subsets; Tegafur | 2000 |
Oral indomethacin and ranitidine in advanced melanoma: a phase II study.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Combined Chemotherapy Protocols; Disease Progression; Female; Follow-Up Studies; Histamine H2 Antagonists; Humans; Indomethacin; Liver Neoplasms; Lymphatic Metastasis; Male; Melanoma; Middle Aged; Pelvis; Ranitidine; Remission Induction; Skin Neoplasms; Uveal Neoplasms | 1996 |
37 other study(ies) available for indomethacin and Cancer of Liver
| Article | Year |
|---|---|
Synthesis and biological evaluation of novel podophyllotoxin-NSAIDs conjugates as multifunctional anti-MDR agents against resistant human hepatocellular carcinoma Bel-7402/5-FU cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Carcinoma, Hepatocellular; Cell Cycle; Cell Line; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Liver Neoplasms; Molecular Structure; Podophyllotoxin; Structure-Activity Relationship | 2017 |
Hypoxia-Activated and Indomethacin-Mediated Theranostic Prodrug Releasing Drug On-Demand for Tumor Imaging and Therapy.
Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Carcinoma, Hepatocellular; Cell Proliferation; Floxuridine; Fluorescent Dyes; Humans; Hypoxia; Indomethacin; Liver Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Prodrugs; Theranostic Nanomedicine; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2019 |
Functional Role of Novel Indomethacin Derivatives for the Treatment of Hepatocellular Carcinoma Through Inhibition of Platelet-Derived Growth Factor.
Topics: Carcinoma, Hepatocellular; Humans; Indomethacin; Liver Neoplasms; Molecular Docking Simulation; Platelet-Derived Growth Factor | 2021 |
Long-term use of indomethacin leads to poor prognoses through promoting the expression of PD-1 and PD-L2 via TRIF/NF-κB pathway and JAK/STAT3 pathway to inhibit TNF-α and IFN-γ in hepatocellular carcinoma.
Topics: Adaptor Proteins, Vesicular Transport; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carcinoma, Hepatocellular; Cell Line, Tumor; Indomethacin; Interferon-gamma; Janus Kinases; Liver Neoplasms; Lung Neoplasms; Male; Mice, Inbred BALB C; NF-kappa B; Prognosis; Programmed Cell Death 1 Ligand 2 Protein; Programmed Cell Death 1 Receptor; STAT3 Transcription Factor; Tumor Necrosis Factor-alpha | 2015 |
[Synthesis of colon-specific prodrug of indomethacin and its inhibitory effect on liver metastasis from colon cancer].
Topics: Amylose; Animals; Colon; Colonic Neoplasms; Delayed-Action Preparations; Drug Delivery Systems; HT29 Cells; Humans; Indomethacin; Liver Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Prodrugs; Random Allocation; Rats; Rats, Sprague-Dawley | 2010 |
Indomethacin and SC236 enhance the cytotoxicity of doxorubicin in human hepatocellular carcinoma cells via inhibiting P-glycoprotein and MRP1 expression.
Topics: Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Separation; Cyclooxygenase 2 Inhibitors; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Flow Cytometry; Humans; Indomethacin; Liver Neoplasms; Microscopy, Confocal; Multidrug Resistance-Associated Proteins; Pyrazoles; Sulfonamides | 2011 |
Cyclooxygenase-2 and inducible nitric oxide synthase in omental arteries harvested from patients with severe liver diseases: immuno-localization and influence on vascular tone.
Topics: Adult; Arteries; Blotting, Western; Carcinoma, Hepatocellular; Case-Control Studies; Cyclooxygenase 2; Dilatation, Pathologic; Female; Hepatitis, Viral, Human; Humans; Immunohistochemistry; Indomethacin; Isoenzymes; Liver Failure; Liver Neoplasms; Liver Transplantation; Male; Membrane Proteins; Middle Aged; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrobenzenes; Norepinephrine; Omentum; Prostaglandin-Endoperoxide Synthases; Severity of Illness Index; Sulfonamides; Up-Regulation | 2003 |
Cyclooxygenase inhibition is associated with downregulation of apolipoprotein AI promoter activity in cultured hepatoma cell line HepG2.
Topics: Apolipoprotein A-I; Arachidonic Acid; Aspirin; Blotting, Northern; Blotting, Western; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Nucleus; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Down-Regulation; Humans; Hydroxyeicosatetraenoic Acids; Indomethacin; Isoenzymes; Liver Neoplasms; Membrane Proteins; Plasmids; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; Prostaglandins; RNA, Messenger; Thromboxane B2; Transcription, Genetic | 2004 |
Effects of the Geiji-Bokryung-Hwan on carrageenan-induced inflammation in mice and cyclooxygenase-2 in hepatoma cells of HepG2 and Hep3B.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carcinoma, Hepatocellular; Carrageenan; Cell Line, Tumor; Cyclooxygenase 2; Dinoprostone; Edema; Female; Hindlimb; Humans; Hydroquinones; Indomethacin; Inflammation; Isoenzymes; Liver Neoplasms; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Phenylbutazone; Plant Extracts; Prostaglandin-Endoperoxide Synthases; Protein-Tyrosine Kinases; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tyrphostins | 2004 |
Indomethacin therapy in symptomatic hepatic neoplasms.
Topics: Adenocarcinoma; Aged; Carcinoma, Hepatocellular; Carcinoma, Squamous Cell; Female; Humans; Indomethacin; Liver Neoplasms; Male; Palliative Care | 1982 |
Effects of stimulators and inhibitors on arachidonic acid metabolism in hepatoma.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Butylated Hydroxytoluene; Carcinoma, Hepatocellular; Indomethacin; Liver Neoplasms; Prostaglandins; Rats; Sodium Salicylate; Thromboxane B2; Thromboxanes; Tryptophan | 1981 |
Metastatic pancreatic vipoma: a case report of clinical response following treatment with corticosteroids and actinomycin D.
Topics: Adenoma, Islet Cell; Dactinomycin; Female; Humans; Indomethacin; Liver Neoplasms; Middle Aged; Pancreatic Neoplasms; Prednisolone; Vasoactive Intestinal Peptide; Vipoma | 1982 |
Influence of various prostaglandin synthesis inhibitors on DMH-induced rat colon cancer.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Colonic Neoplasms; Dimethylhydrazines; Drinking; Eating; Indomethacin; Liver Neoplasms; Lymphatic Metastasis; Male; Meclofenamic Acid; Peritoneal Neoplasms; Prostaglandin Antagonists; Rats; Rats, Inbred Strains | 1984 |
Antipyretic effects of indomethacin in liver metastases of solid tumors.
Topics: Drug Administration Schedule; Female; Fever; Humans; Indomethacin; Liver Neoplasms; Male; Middle Aged | 1982 |
Control of fever associated with visceral cancers by indomethacin.
Topics: Abdominal Neoplasms; Adenocarcinoma; Adult; Aged; Female; Fever; Humans; Indomethacin; Liver Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Peritoneal Neoplasms; Prostaglandins E | 1981 |
Effect of combined administration of a synthetic low-toxicity lipid A derivative, DT-5461a, and indomethacin in various experimental tumor models of colon 26 carcinoma in mice.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Dinoprostone; Disaccharides; Drug Screening Assays, Antitumor; Indomethacin; Lipid A; Liver Neoplasms; Lung Neoplasms; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Peritoneal Neoplasms; Tumor Necrosis Factor-alpha | 1995 |
Interleukin-1 alpha induces corticotropin-releasing factor secretion and synthesis from NPLC-KC cells through various second messenger pathways.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Carcinoma, Hepatocellular; Corticotropin-Releasing Hormone; Cyclic AMP-Dependent Protein Kinases; Humans; Indomethacin; Interleukin-1; Isoquinolines; Liver Neoplasms; Peptides; Piperazines; Protein Kinase C; Radioimmunoassay; Second Messenger Systems; Tumor Cells, Cultured | 1994 |
[In vivo studies on PGE2 production by human hepatocellular carcinoma xenografts in nude mice].
Topics: Animals; Carcinoma, Hepatocellular; Dinoprostone; Humans; Indomethacin; Injections, Intraperitoneal; Liver Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Radioimmunoassay | 1993 |
Redox-sensitive interaction between KIAA0132 and Nrf2 mediates indomethacin-induced expression of gamma-glutamylcysteine synthetase.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Blotting, Northern; Carcinoma, Hepatocellular; Carrier Proteins; Chloramphenicol O-Acetyltransferase; DNA-Binding Proteins; Fluorescent Antibody Technique, Indirect; Glutamate-Cysteine Ligase; Glutathione; Humans; Ibuprofen; Indomethacin; Leucine Zippers; Liver Neoplasms; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase Kinases; NF-E2-Related Factor 2; Oxidation-Reduction; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; RNA, Messenger; Trans-Activators; Transfection; Tumor Cells, Cultured | 2002 |
Evidence for prostaglandin-producing supressor cells in HCV patients with normal ALT.
Topics: Alanine Transaminase; Carcinoma, Hepatocellular; Carrier State; Dinoprostone; Hepatitis C Antigens; Hepatitis C, Chronic; Humans; Indomethacin; Liver; Liver Neoplasms; Lymphocyte Activation; T-Lymphocytes, Regulatory | 2002 |
Letter: Prostaglandins, indomethacin and hypercalcemia in neoplastic disease.
Topics: Aged; Carcinoma, Squamous Cell; Humans; Hypercalcemia; Indomethacin; Liver Neoplasms; Lung Neoplasms; Male; Neoplasm Metastasis; Parathyroid Hormone; Plicamycin; Prostaglandins | 1975 |
Decreased disappearance rate of 1-(2-tetrahydrofuryl)-5-fluorouracil (FT-207) from the blood and its unresponsiveness to tocophreyl nicotinate and indomethacin in patients with primary hepatocellular carcinoma.
Topics: Carcinoma, Hepatocellular; Fluorouracil; Humans; Indomethacin; Kinetics; Liver Cirrhosis; Liver Neoplasms; Microsomes, Liver; Nicotinic Acids; Tegafur; Vitamin E | 1979 |
Elevated prostaglandins and suppressed parathyroid hormone associated with hypercalcemia and renal cell carcinoma.
Topics: Adenocarcinoma; Calcium; Humans; Hypercalcemia; Indomethacin; Kidney Cortex; Liver; Liver Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Parathyroid Hormone; Phosphates; Prostaglandins | 1975 |
[Comprehensive "4-step analgesic ladder" therapy in treating cancer-related pain-analysis of 486 cases].
Topics: Adult; Aged; Aged, 80 and over; Colonic Neoplasms; Drugs, Chinese Herbal; Female; Humans; Indomethacin; Liver Neoplasms; Male; Middle Aged; Narcotics; Pain, Intractable; Phenylbutazone; Rectal Neoplasms | 1992 |
Effects of antiplatelet agents alone or in combinations on platelet aggregation and on liver metastases from a human pancreatic adenocarcinoma in the nude mouse.
Topics: Adenocarcinoma; Animals; Colforsin; Drug Interactions; Humans; Indomethacin; Ketoconazole; Liver Neoplasms; Mice; Mice, Nude; Neoplasm Transplantation; Pancreatic Neoplasms; Platelet Aggregation; Platelet Aggregation Inhibitors; Tumor Cells, Cultured; Verapamil | 1991 |
Quantity and saturation degree of dietary fats as modulators of oxidative stress and chemically-induced liver tumours in rats.
Topics: Animals; Biomarkers; Blood Chemical Analysis; Cell Transformation, Neoplastic; Cholesterol; Dietary Fats; Dimethylnitrosamine; Glutathione; Indomethacin; Lipid Peroxidation; Lipids; Liver; Liver Neoplasms; Male; Peptidyl Transferases; Rats; Rats, Inbred Strains; Triglycerides; Weight Gain | 1990 |
[In vivo and in vitro studies on PGE2 production and function in human hepatocellular carcinoma].
Topics: Animals; Carcinoma, Hepatocellular; Dinoprostone; Humans; Indomethacin; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Neoplasm Transplantation; Time Factors; Tumor Cells, Cultured | 1989 |
Elevated levels of prostaglandin E2 in the liver of rats fed a choline deficient diet: possible involvement in liver tumor promotion.
Topics: Animals; Choline Deficiency; Diethylhexyl Phthalate; Dinoprostone; Fish Oils; gamma-Glutamyltransferase; Indomethacin; Liver; Liver Neoplasms; Male; Pyrimidines; Rats; Rats, Inbred Strains | 1989 |
Prostaglandin-E-producing hepatocellular carcinoma with hypercalcemia.
Topics: Aged; Carcinoma, Hepatocellular; Humans; Hypercalcemia; Indomethacin; Liver Neoplasms; Male; Phosphates; Prostaglandins E | 1988 |
Effects of arachidonic acid and indomethacin on sister-chromatid exchange induction by polycyclic aromatic hydrocarbons in mammalian cell lines.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Arachidonic Acid; Arachidonic Acids; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Carcinoma, Hepatocellular; Cell Line; Cricetinae; Cricetulus; Drug Synergism; Enzyme Induction; Humans; Indomethacin; Liver Neoplasms; Rats; Sister Chromatid Exchange | 1986 |
Long survival of diarrhea-associated hepatocarcinoma treated with Adriamycin and indomethacin. A case report.
Topics: Adult; Carcinoma, Hepatocellular; Diarrhea; Doxorubicin; Drug Therapy, Combination; Humans; Indomethacin; Liver Neoplasms; Male; Paraneoplastic Syndromes; Prognosis | 1986 |
Decreased interleukin 1 activity in culture supernatant of lipopolysaccharide stimulated monocytes from patients with liver cirrhosis and hepatocellular carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Body Temperature; C-Reactive Protein; Carcinoma, Hepatocellular; Dinoprostone; Female; Humans; Indomethacin; Interleukin-1; Lipopolysaccharides; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged; Monocytes; Prostaglandins E | 1987 |
Absence of correlation between liver metastases and unexplained fever episodes.
Topics: Adrenal Cortex Hormones; Aged; Breast Neoplasms; Diagnostic Errors; Digestive System Neoplasms; Female; Fever of Unknown Origin; Humans; Indomethacin; Laparoscopy; Laparotomy; Liver Neoplasms; Male; Palpation; Radiography; Retrospective Studies | 1985 |
Differential distribution of B16F10 melanoma cells in the liver lobule.
Topics: Animals; Cell Line; Female; Indomethacin; Liver Neoplasms; Male; Melanoma; Mice; Mice, Inbred Strains; Microcirculation; Microscopy, Electron; Neoplasm Metastasis; Neoplasms, Experimental; Rats | 1988 |
Acute renal failure and death following sequential intermediate-dose methotrexate and 5-FU: a possible adverse effect due to concomitant indomethacin administration.
Topics: Acute Kidney Injury; Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Interactions; Fluorouracil; Humans; Indomethacin; Liver Neoplasms; Male; Methotrexate; Middle Aged | 1985 |
Production of histamine-like and prostaglandin-like substances from serum incubated with rat, dog, mouse or human tumours.
Topics: Acetates; Animals; Aspirin; Carcinoma, Hepatocellular; Complement System Proteins; Dogs; Histamine; Humans; Hydrogen-Ion Concentration; Immune Sera; In Vitro Techniques; Indomethacin; Lipids; Liver; Liver Neoplasms; Mice; Muscle Contraction; Muscles; Neoplasms, Experimental; Prostaglandin Antagonists; Prostaglandins; Rats; Stomach; Time Factors | 1973 |
[Iatrogenic gastroduodenal ulcerations. Corticosteroids excluded].
Topics: Aged; Bone Neoplasms; Carcinoma, Squamous Cell; Cyclophosphamide; Duodenal Ulcer; Female; Humans; Indomethacin; Joint Diseases; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Myocardial Infarction; Phenindione; Phenylbutazone; Potassium Chloride; Pulmonary Heart Disease; Stomach Ulcer | 1973 |