indomethacin has been researched along with Cancer of Gastrointestinal Tract in 10 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Unselected cancer patients (n = 108) who experienced progressive cachexia were randomized to receive either anti-inflammatory treatment alone (indomethacin) or recombinant erythropoietin plus indomethacin to prevent the appearance of disease-induced anemia and thereby protect patients' exercise capacity." | 5.11 | Effects of recombinant erythropoietin in palliative treatment of unselected cancer patients. ( Daneryd, P; Fouladiun, M; Hyltander, A; Körner, U; Lindholm, E; Lundholm, K, 2004) |
| "Indomethacin was given to four patients with hypercalcemia with no effect on serum calcium levels in any cases." | 1.27 | Hypercalcemia of cancer in the digestive tract. ( Furuta, S; Monno, S; Nagata, A, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (40.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lindholm, E | 1 |
| Daneryd, P | 1 |
| Körner, U | 1 |
| Hyltander, A | 1 |
| Fouladiun, M | 1 |
| Lundholm, K | 1 |
| Yokoigawa, N | 1 |
| Takeuchi, N | 1 |
| Toda, M | 1 |
| Inoue, M | 1 |
| Kaibori, M | 1 |
| Yanagida, H | 1 |
| Inaba, T | 1 |
| Tanaka, H | 1 |
| Ogura, T | 1 |
| Takada, H | 1 |
| Okumura, T | 1 |
| Kwon, AH | 1 |
| Kamiyama, Y | 1 |
| Nakada, H | 1 |
| Tanaka, T | 1 |
| Suzui, M | 1 |
| Kojima, T | 1 |
| Okamoto, K | 1 |
| Wang, A | 1 |
| Mori, H | 1 |
| Tsuji, S | 1 |
| Kawano, S | 1 |
| Sawaoka, H | 1 |
| Takei, Y | 1 |
| Kobayashi, I | 1 |
| Nagano, K | 1 |
| Fusamoto, H | 1 |
| Kamada, T | 1 |
| Wright, NA | 1 |
| Hoffmann, W | 1 |
| Otto, WR | 1 |
| Rio, MC | 1 |
| Thim, L | 1 |
| Azarschab, P | 1 |
| Al-Azzeh, E | 1 |
| Kornberger, W | 1 |
| Gött, P | 1 |
| Shparik, IaV | 1 |
| Koyama, H | 1 |
| Narisawa, T | 1 |
| Kodama, M | 1 |
| Ishikawa, K | 1 |
| Kusaka, H | 1 |
| Yamazaki, Y | 1 |
| Koyama, K | 1 |
| Monno, S | 1 |
| Nagata, A | 1 |
| Furuta, S | 1 |
| Kiczka, W | 1 |
| Szkaradkiewicz, A | 1 |
1 review available for indomethacin and Cancer of Gastrointestinal Tract
| Article | Year |
|---|---|
Rolling in the clover: trefoil factor family (TFF)-domain peptides, cell migration and cancer.
Topics: Animals; Cell Movement; Consensus Sequence; Gastrointestinal Neoplasms; Growth Substances; Indometha | 1997 |
1 trial available for indomethacin and Cancer of Gastrointestinal Tract
| Article | Year |
|---|---|
Effects of recombinant erythropoietin in palliative treatment of unselected cancer patients.
Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Cachexia; Drug Therapy, Combination; | 2004 |
8 other studies available for indomethacin and Cancer of Gastrointestinal Tract
| Article | Year |
|---|---|
Overproduction of PGE2 in peripheral blood monocytes of gastrointestinal cancer patients with mucins in their bloodstream.
Topics: Amino Acid Sequence; Blood Proteins; Cells, Cultured; Cyclooxygenase 2; Cyclooxygenase Inhibitors; D | 2007 |
Chemoprevention of the naturally occurring carcinogen 1-hydroxyanthraquinone-induced carcinogenesis by the nonsteroidal anti-inflammatory drug indomethacin in rats.
Topics: Animals; Anthraquinones; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Carcinoge | 1995 |
Evidences for involvement of cyclooxygenase-2 in proliferation of two gastrointestinal cancer cell lines.
Topics: Cell Division; Cell Line; Colonic Neoplasms; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 In | 1996 |
Aspirin promotes TFF2 gene activation in human gastric cancer cell lines.
Topics: Arachidonic Acid; Aspirin; Gastrointestinal Neoplasms; Genes, Reporter; Growth Substances; Humans; I | 2001 |
[The functional status of natural killer cells in patients with cancer of the digestive organs].
Topics: Cytotoxicity, Immunologic; Gastrointestinal Neoplasms; Humans; Indomethacin; Interferon alpha-2; Int | 1989 |
[Potent effects of the prostaglandin synthesis inhibitor indomethacin on the cellular immune response in gastrointestinal cancer patients].
Topics: Animals; Combined Modality Therapy; Gastrointestinal Neoplasms; Humans; Immunity, Cellular; Indometh | 1989 |
Hypercalcemia of cancer in the digestive tract.
Topics: Aged; Aged, 80 and over; Bone Neoplasms; Female; Gastrointestinal Neoplasms; Humans; Hypercalcemia; | 1987 |
Suppression of monocyte mediated anti U562 cytotoxicity by soluble factors in the serum of cancer patients and in the supernatant of K562 cell culture.
Topics: Adult; Aged; Cells, Cultured; Cytotoxicity, Immunologic; Esophageal Neoplasms; Gastrointestinal Neop | 1986 |