indomethacin has been researched along with Brain Vascular Disorders in 12 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Indomethacin pretreatment of aortae from 20 week old SHRSP restored acetylcholine-induced EDR to a level comparable with that in age-matched WKY." | 1.29 | Enhancement of endothelium-dependent relaxation in the aorta from stroke-prone spontaneously hypertensive rats at developmental stages of hypertension. ( Hamano, M; Mashiko, S; Onda, T; Tomita, I; Tomita, T, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (50.00) | 18.7374 |
| 1990's | 4 (33.33) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lorenzo Fernández, P | 1 |
| Agostoni, A | 1 |
| de Boer, AC | 1 |
| Genton, E | 1 |
| Turpie, AG | 1 |
| Nagaoka, A | 1 |
| Kakihana, M | 1 |
| Iwatsuka, H | 1 |
| Onda, T | 1 |
| Mashiko, S | 1 |
| Hamano, M | 1 |
| Tomita, I | 1 |
| Tomita, T | 1 |
| McIntyre, M | 1 |
| Hamilton, CA | 1 |
| Rees, DD | 1 |
| Reid, JL | 1 |
| Dominiczak, AF | 1 |
| Melton, SM | 1 |
| Davis, KA | 1 |
| Moomey, CB | 1 |
| Fabian, TC | 1 |
| Proctor, KG | 1 |
| Kulkarni, M | 1 |
| Armstead, WM | 1 |
| Takemoto, F | 1 |
| Miyanoshita, A | 1 |
| Shimamura, K | 1 |
| Sunano, S | 1 |
| Endou, H | 1 |
| Walker, V | 1 |
| Pickard, JD | 1 |
| Sugimoto, T | 1 |
| Tobian, L | 1 |
| Ganguli, MC | 1 |
| Bakunts, GO | 1 |
| Koval'chuk, LV | 1 |
| Cheknev, SB | 1 |
| Ul'ianova, TIu | 1 |
| Pavliuk, AS | 1 |
2 reviews available for indomethacin and Brain Vascular Disorders
| Article | Year |
|---|---|
Chemistry, measurement, and clinical significance of platelet specific proteins.
Topics: Aspirin; Beta-Globulins; beta-Thromboglobulin; Blood Coagulation; Blood Coagulation Factors; Blood P | 1982 |
Prostaglandins, thromboxane, leukotrienes and the cerebral circulation in health and disease.
Topics: Animals; Arachidonic Acids; Brain; Brain Edema; Brain Ischemia; Cerebrovascular Circulation; Cerebro | 1985 |
10 other studies available for indomethacin and Brain Vascular Disorders
| Article | Year |
|---|---|
[Neuroprotection by aspirin in cerebrovascular pathology].
Topics: Adenosine Triphosphate; Algorithms; Amino Acid Transport System X-AG; Animals; Aspirin; Brain Ischem | 2002 |
[Current status of medical treatment].
Topics: Aminophylline; Animals; Anticoagulants; Aspirin; Barbiturates; Brain Ischemia; Cerebrovascular Disor | 1980 |
Effects of prostaglandin inhibitors on the onset of proteinuria and stroke in stroke-prone spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Carbazoles; Cerebrovascular Disorders; Hypertension; Indomethacin; Prostagl | 1981 |
Enhancement of endothelium-dependent relaxation in the aorta from stroke-prone spontaneously hypertensive rats at developmental stages of hypertension.
Topics: Acetylcholine; Animals; Aorta; Cerebrovascular Disorders; Dose-Response Relationship, Drug; Endothel | 1994 |
Sex differences in the abundance of endothelial nitric oxide in a model of genetic hypertension.
Topics: Animals; Aorta, Thoracic; Blood Pressure; Body Weight; Carbachol; Cerebrovascular Disorders; Ditioca | 1997 |
Mediator-dependent secondary injury after unilateral blunt thoracic trauma.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Transfusion; Cerebrovascular Disorders; Cont | 1999 |
Superoxide generation links nociceptin/orphanin FQ (NOC/oFQ) release to impaired N-methyl-D-aspartate cerebrovasodilation after brain injury.
Topics: Animals; Animals, Newborn; Cerebral Arteries; Cerebrovascular Circulation; Cerebrovascular Disorders | 2000 |
Intranephron PGE2 production in stroke-prone spontaneously hypertensive rats.
Topics: Aging; Animals; Arachidonic Acid; Arachidonic Acids; Arginine Vasopressin; Calcimycin; Cerebrovascul | 1990 |
High potassium diets protect against dysfunction of endothelial cells in stroke-prone spontaneously hypertensive rats.
Topics: Acetylcholine; Administration, Oral; Animals; Aorta, Thoracic; Biological Products; Cerebrovascular | 1988 |
[Functional activity of natural killers and lymphocyte antibody-dependent cytotoxicity in patients with acute disorders of the cerebral circulation].
Topics: Acute Disease; Aged; Antibody-Dependent Cell Cytotoxicity; Cells, Cultured; Cerebrovascular Disorder | 1988 |