Page last updated: 2024-10-29

indomethacin and Brain Inflammation

indomethacin has been researched along with Brain Inflammation in 6 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Research Excerpts

ExcerptRelevanceReference
"A model of brain inflammation has recently been developed in mice using intraventricular injection of carrageenan (CAR)."5.27Effect of dexamethasone, indomethacin, ibuprofen, and probenecid on carrageenan-induced brain inflammation. ( Ellis, EF; Gamache, DA, 1986)
"The neurologic manifestations of neonatal hyperbilirubinemia in the central nervous system (CNS) exhibit high variations in the severity and appearance of motor, auditory and cognitive symptoms, which is suggestive of a still unexplained selective topography of bilirubin-induced damage."3.85Evaluation of region selective bilirubin-induced brain damage as a basis for a pharmacological treatment. ( Bottin, C; Dal Ben, M; Gazzin, S; Tiribelli, C; Zanconati, F, 2017)
"A model of brain inflammation has recently been developed in mice using intraventricular injection of carrageenan (CAR)."1.27Effect of dexamethasone, indomethacin, ibuprofen, and probenecid on carrageenan-induced brain inflammation. ( Ellis, EF; Gamache, DA, 1986)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's3 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ji, R1
Tian, S1
Lu, HJ1
Lu, Q2
Zheng, Y1
Wang, X1
Ding, J1
Li, Q1
Dal Ben, M1
Bottin, C1
Zanconati, F1
Tiribelli, C1
Gazzin, S1
Leroux, P1
Hennebert, C1
Catteau, J1
Legros, H1
Hennebert, O1
Laudenbach, V1
Marret, S1
Guo, JT1
Yu, J1
Grass, D1
de Beer, FC1
Kindy, MS1
Pascual, M1
Blanco, AM1
Cauli, O1
MiƱarro, J1
Guerri, C1
Gamache, DA1
Ellis, EF1

Other Studies

6 other studies available for indomethacin and Brain Inflammation

ArticleYear
TAM receptors affect adult brain neurogenesis by negative regulation of microglial cell activation.
    Journal of immunology (Baltimore, Md. : 1950), 2013, Dec-15, Volume: 191, Issue:12

    Topics: Animals; Astrocytes; Axl Receptor Tyrosine Kinase; c-Mer Tyrosine Kinase; Cells, Cultured; Culture M

2013
Evaluation of region selective bilirubin-induced brain damage as a basis for a pharmacological treatment.
    Scientific reports, 2017, 01-19, Volume: 7

    Topics: Animals; Bilirubin; Brain; Brain Diseases, Metabolic; Cell Survival; Curcumin; Encephalitis; Hyperbi

2017
Neuroprotective effects vary across nonsteroidal antiinflammatory drugs in a mouse model of developing excitotoxic brain injury.
    Neuroscience, 2010, May-19, Volume: 167, Issue:3

    Topics: Acetaminophen; Adrenal Cortex Hormones; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Ste

2010
Inflammation-dependent cerebral deposition of serum amyloid a protein in a mouse model of amyloidosis.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, Jul-15, Volume: 22, Issue:14

    Topics: Age Factors; Amyloidosis; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Northern; Brai

2002
Intermittent ethanol exposure induces inflammatory brain damage and causes long-term behavioural alterations in adolescent rats.
    The European journal of neuroscience, 2007, Volume: 25, Issue:2

    Topics: Analysis of Variance; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Behavior,

2007
Effect of dexamethasone, indomethacin, ibuprofen, and probenecid on carrageenan-induced brain inflammation.
    Journal of neurosurgery, 1986, Volume: 65, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Brain Edema; Capillary Permeability; Carrageenan; Cerebrovascular

1986