indomethacin has been researched along with Bone Marrow Diseases in 6 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Bone Marrow Diseases: Diseases involving the BONE MARROW.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Treatment of mice with 100 micrograms of indomethacin, a potent inhibitor of prostaglandin synthesis, prior to the injection of rhuIL-1 alpha, prevented the increase in number of bone metastases." | 3.68 | Effect of IL-1 on experimental bone/bone-marrow metastases. ( Arguello, F; Baggs, RB; Cohen, HJ; Frantz, CN; Graves, BT; Harwell, SE, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (66.67) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schmieder, A | 1 |
| Damm, F | 1 |
| Haus, G | 1 |
| Lentz, K | 1 |
| Goerdt, S | 1 |
| Peitsch, WK | 1 |
| Mitarnun, W | 1 |
| Peerabool, R | 1 |
| Arguello, F | 1 |
| Baggs, RB | 1 |
| Graves, BT | 1 |
| Harwell, SE | 1 |
| Cohen, HJ | 1 |
| Frantz, CN | 1 |
| Kalf, GF | 1 |
| Schlosser, MJ | 1 |
| Renz, JF | 1 |
| Pirozzi, SJ | 1 |
| Berbatis, CG | 1 |
| Hurley, SF | 1 |
| Jaros, Z | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Atavistic Chemotherapy and Immunotherapy in Advanced, Metastatic, and Otherwise Incurable and Lethal Cancers Under Conventional Treatments[NCT02366884] | Phase 2 | 250 participants (Anticipated) | Interventional | 2011-07-26 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 other studies available for indomethacin and Bone Marrow Diseases
| Article | Year |
|---|---|
Extended eosinophilic pustular folliculitis with reactive bone marrow hypereosinophilia responsive to combined treatment with indomethacin, dapsone, and narrow-band UVB phototherapy.
Topics: Bone Marrow Diseases; Combined Modality Therapy; Dapsone; Eosinophilia; Folliculitis; Humans; Indome | 2013 |
Blood dyscrasia evolving into acute lymphoblastic leukemia following ingestion of phenylbutazone, indomethacin, dexamethasone and prednisolone.
Topics: Adult; Bone Marrow Diseases; Dexamethasone; Humans; Indomethacin; Leukemia, Lymphoid; Male; Pancytop | 1983 |
Effect of IL-1 on experimental bone/bone-marrow metastases.
Topics: Animals; Bone Marrow Diseases; Bone Neoplasms; Granulocyte-Macrophage Colony-Stimulating Factor; Ind | 1992 |
Prevention of benzene-induced myelotoxicity by nonsteroidal anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Benzene; Bone Marrow Diseases; | 1989 |
Drug-bone marrow interactions.
Topics: Anemia, Aplastic; Australia; Bone Marrow Diseases; Diclofenac; Drug-Related Side Effects and Adverse | 1987 |
[Influence of drugs used in rheumatology on the blood].
Topics: Analgesics; Anti-Inflammatory Agents; Bone Marrow Diseases; Chloroquine; Corticosterone; Gold; Hemat | 1971 |