Page last updated: 2024-10-29

indomethacin and Bone Diseases

indomethacin has been researched along with Bone Diseases in 21 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Bone Diseases: Diseases of BONES.

Research Excerpts

ExcerptRelevanceReference
"Glucametacine was also statistically (p < 0,05) better from the tolerance point of view."2.65["Double-blind" clinical study of a non-steroid anti-inflammatory drug: glucametacine]. ( Franchin, F; Pipino, F, 1980)
"Indomethacin was significantly better than fenbufen with respect to two indices and, overall, appeared more effective in the dosages tested."2.64Fenbufen compared with indomethacin in osteoarthrosis. ( Buxton, R; Grennan, DM; Palmer, DG, 1978)
"There were no recurrences with either approach until the last follow-up (mean, 56 months)."1.35Management of eosinophilic granuloma occurring in the appendicular skeleton in children. ( Cho, HS; Han, I; Kim, HS; Lee, SH; Oh, JH; Suh, ES, 2009)
"Eight patients did not experience EG recurrence, however, 1 patient developed additional lesions 2 years after surgical excision."1.34Eosinophilic granuloma of the skull: a retrospective analysis. ( Hamm, IS; Hwang, JH; Hwang, SK; Park, J; Park, SH; Park, YM, 2007)
"Two rare cases of aplastic anemia after prolonged ingestion of indomethacin are described."1.26Aplastic anemia after prolonged ingestion of indomethacin. ( Kornberg, A; Rachmilewitz, EA, 1982)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-199017 (80.95)18.7374
1990's0 (0.00)18.2507
2000's2 (9.52)29.6817
2010's1 (4.76)24.3611
2020's1 (4.76)2.80

Authors

AuthorsStudies
De Benedittis, D1
Mohamed, S1
Rizzo, L1
Santopietro, M1
Palumbo, G1
Cardarelli, L1
Roggini, M1
Giona, F1
Braier, J1
Rosso, D1
Pollono, D1
Rey, G1
Lagomarsino, E1
Latella, A1
Zubizarreta, P1
Han, I1
Suh, ES1
Lee, SH1
Cho, HS1
Oh, JH1
Kim, HS1
Park, SH1
Park, J1
Hwang, JH1
Hwang, SK1
Hamm, IS1
Park, YM1
Kornberg, A1
Rachmilewitz, EA1
Pipino, F1
Franchin, F1
Schoenberg, LM1
Kushner, I1
Khan, MA1
Backhouse, CI1
Engler, C1
English, JR1
Leardini, G1
Mattara, L1
Mazzucco, A1
Rossetto, G1
Woolf, D1
Huskisson, EC1
Nicol, CG1
Buxton, R1
Grennan, DM1
Palmer, DG1
Gottlieb, NL1
Sis Riskin, WG1
Franchimont, P1
Van Cauwenberge, H1
Rau, R1
Lobsiger, M1
Gross, D1
Stalnikowicz, R1
Pollak, D1
Eliakim, A1
Wengrower, D1
Fich, A1
Goldin, E1
Ligumsky, M1
Rachmilewitz, D1
Heere, LP1
Brodie, GN1
Fessl, O1
Pohl, W1
Hoekstra, WG1
Fantini, F1
Colombo, B1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Prospective Institutional Study for the Treatment of Children With Newly Diagnosed Langerhans Cell Histiocytosis Using a Cytarabine Contained Protocol[NCT04773366]Phase 3200 participants (Anticipated)Interventional2018-07-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for indomethacin and Bone Diseases

ArticleYear
Skeletal and skin lesions of zinc-deficiency chickens and swine. Possible relationship to "connective tissue diseases" of man.
    The American journal of clinical nutrition, 1969, Volume: 22, Issue:9

    Topics: Amino Acids; Animals; Bone Diseases; Chelating Agents; Chickens; Collagen Diseases; Deficiency Disea

1969

Trials

9 trials available for indomethacin and Bone Diseases

ArticleYear
["Double-blind" clinical study of a non-steroid anti-inflammatory drug: glucametacine].
    Minerva medica, 1980, Oct-13, Volume: 71, Issue:39

    Topics: Adult; Aged; Anti-Inflammatory Agents; Bone Diseases; Clinical Trials as Topic; Female; Glucosamine;

1980
Indomethacin and benorylate in osteoarthrosis of the hip.
    The Practitioner, 1978, Volume: 221, Issue:1325

    Topics: Aged; Bone Diseases; Clinical Trials as Topic; Double-Blind Method; Female; Hip Joint; Humans; Indom

1978
Fenbufen compared with indomethacin in osteoarthrosis.
    Current medical research and opinion, 1978, Volume: 5, Issue:9

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Biphenyl Compounds; Bone Diseases; Clinical Tr

1978
[Treatment of osteoarthrosis by fenoprofen (author's transl)].
    Journal belge de rhumatologie et de medecine physique = Belgisch tijdschrift voor reumatologie en fysische geneeskunde, 1976, Volume: 31 Suppl

    Topics: Adult; Aged; Bone Diseases; Clinical Trials as Topic; Female; Fenoprofen; Humans; Indomethacin; Join

1976
[Treatment of severe osteoarthrosis of the knee and the hip with tolmentin. (A double-blind comparison with Indomethacin) (author's transl)].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1977, Feb-01, Volume: 66, Issue:5

    Topics: Bone Diseases; Drug Evaluation; Hip; Humans; Indomethacin; Joint Diseases; Knee; Pyrroles; Tolmetin

1977
Cimetidine decreases indomethacin induced duodenal mucosal damage in patients with acute musculoskeletal disorders.
    Gut, 1988, Volume: 29, Issue:11

    Topics: Adolescent; Adult; Aged; Bone Diseases; Cimetidine; Clinical Trials as Topic; Double-Blind Method; D

1988
Piroxicam in acute musculoskeletal disorders and sports injuries.
    The American journal of medicine, 1988, May-20, Volume: 84, Issue:5A

    Topics: Activities of Daily Living; Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Athl

1988
Letter: Indomethacin and bone pain.
    Lancet (London, England), 1974, Jun-08, Volume: 1, Issue:7867

    Topics: Bone Diseases; Clinical Trials as Topic; Humans; Indomethacin; Joint Diseases; Pain

1974
[Postoperative use of indomethacin in orthopedics].
    Zeitschrift fur Orthopadie und ihre Grenzgebiete, 1969, Volume: 106, Issue:1

    Topics: Bone Diseases; Humans; Indomethacin; Joint Diseases; Oxyphenbutazone; Placebos; Postoperative Care

1969

Other Studies

11 other studies available for indomethacin and Bone Diseases

ArticleYear
Indomethacin is an effective treatment in adults and children with bone Langerhans cell histiocytosis (LCH).
    British journal of haematology, 2020, Volume: 191, Issue:5

    Topics: Adolescent; Adult; Aged; Bone Diseases; Child; Child, Preschool; Female; Follow-Up Studies; Histiocy

2020
Symptomatic bone langerhans cell histiocytosis treated at diagnosis or after reactivation with indomethacin alone.
    Journal of pediatric hematology/oncology, 2014, Volume: 36, Issue:5

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Bone Diseases; Child; Child, Preschool; Female;

2014
Management of eosinophilic granuloma occurring in the appendicular skeleton in children.
    Clinics in orthopedic surgery, 2009, Volume: 1, Issue:2

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Combined Chemotherapy Protocols;

2009
Eosinophilic granuloma of the skull: a retrospective analysis.
    Pediatric neurosurgery, 2007, Volume: 43, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biopsy; Bone Diseases; Chemotherapy, Adjuvant; Child

2007
Aplastic anemia after prolonged ingestion of indomethacin.
    Acta haematologica, 1982, Volume: 67, Issue:2

    Topics: Aged; Anemia, Aplastic; Bone Diseases; Erythropoiesis; Female; Humans; Indomethacin; Joint Diseases;

1982
Concanavalin A-induced transformation of mononuclear cells: influence of plasma from patients receiving anti-inflammatory agents.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1980, Volume: 164, Issue:2

    Topics: Bone Diseases; Cells, Cultured; Concanavalin A; Culture Media; Humans; Ibuprofen; Indomethacin; Lymp

1980
Naproxen sodium and indomethacin in acute musculoskeletal disorders.
    Rheumatology and rehabilitation, 1980, Volume: 19, Issue:2

    Topics: Acute Disease; Adult; Bone Diseases; Female; Humans; Indomethacin; Male; Middle Aged; Muscular Disea

1980
[Therapy of degenerative arthropathies with sodium diclofenac].
    La Clinica terapeutica, 1980, Jun-15, Volume: 93, Issue:5

    Topics: Adult; Aged; Bone Diseases; Diclofenac; Female; Humans; Indomethacin; Joint Diseases; Male; Middle A

1980
Indomethacin and thalassemic osteoarthropathy.
    Annals of internal medicine, 1978, Volume: 89, Issue:3

    Topics: Bone Diseases; Humans; Indomethacin; Joint Diseases; Thalassemia

1978
[Medicamentous therapy of rheumatic diseases in the spa?].
    Munchener medizinische Wochenschrift (1950), 1966, Sep-16, Volume: 108, Issue:37

    Topics: Adrenocorticotropic Hormone; Anti-Inflammatory Agents; Arthritis; Balneology; Bone Diseases; Cortiso

1966
Use of indomethacin in the treatment of osteoarthrosis and other "minor" rheumatic diseases.
    La Clinica terapeutica, 1971, Nov-15, Volume: 59, Issue:3

    Topics: Adult; Aged; Arthritis, Rheumatoid; Bone Diseases; Female; Humans; Indomethacin; Male; Middle Aged;

1971