Page last updated: 2024-10-29

indomethacin and Blunt Injuries

indomethacin has been researched along with Blunt Injuries in 7 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Research Excerpts

ExcerptRelevanceReference
" The aim of the study is to verify the efficacy of the pharmacological blockade of the systemic inflammatory response syndrome (SIRS) in serious blunt chest injuries, and to identify whether the administration of indomethacin as a cyclooxygenase inhibitor could prevent a multiorgan dysfunction (MODS) and a multiorgan failure (MOF)."5.11Systemic inflammatory response syndrome (SIRS) in serious chest injuries: is a pharmacological blockade effective? ( Cervinka, V; Havlícek, K; Motycka, V; Siller, J, 2005)
" The aim is also to find out if the administration of indomethacin as a cyclooxygenase inhibitor could prevent multiorgan dysfunction (MODS) and multiorgan failure (MOF)."5.10[Pharmacologic prevention of SIRS (systemic inflammatory response syndrome) in severe thoracic injuries]. ( Fortová, M; Grofová, Z; Havlícek, K; Motycka, V; Siller, J; Vanác, J, 2003)
"Our study highlighted the efficacy of indomethacin as a pain reducer for acute corneal pathology and suggested that the medication may act on the corneal nociceptors in a qualitative way."5.09Evaluation of the analgesic effect of 0.1% indomethacin solution on corneal abrasions. ( Macri, A; Patrone, G; Rolando, M; Sacca, SC, 1999)
"126 patients with blunt chest injuries were evaluated during 33 months."2.72[Blunt thoracic injury and the oxidation stress]. ( Fortová, M; Grofová, Z; Havlíek, K; Linda, B; Motycka, V; Siller, J, 2006)
"126 patients with blunt chest injuries were evaluated during 33 months."2.72[SIRS and serious blunt thoracic injuries]. ( Fortová, M; Grofová, Z; Havlícek, K; Linda, B; Motycka, V; Siller, J, 2006)
"Posterior scleritis is an unusual disease that may cause serious ocular inflammation and potentially blinding consequences."1.34Isolated bilateral posterior scleritis after eye trauma. ( Ramirez-Ortiz, MA; Vasquez-Resendis, A, 2007)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (14.29)18.2507
2000's6 (85.71)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Motycka, V4
Havlícek, K3
Siller, J4
Grofová, Z3
Vanác, J1
Fortová, M3
Cervinka, V1
Havlíek, K1
Linda, B2
Ramirez-Ortiz, MA1
Vasquez-Resendis, A1
Davis, AK1
Kuhls, DA1
Wulff, R1
Fildes, JJ1
MacIntyre, AD1
Coates, JE1
Zamboni, WA1
Patrone, G1
Sacca, SC1
Macri, A1
Rolando, M1

Trials

5 trials available for indomethacin and Blunt Injuries

ArticleYear
[Pharmacologic prevention of SIRS (systemic inflammatory response syndrome) in severe thoracic injuries].
    Rozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti, 2003, Volume: 82, Issue:9

    Topics: Cyclooxygenase Inhibitors; Humans; Indomethacin; Multiple Organ Failure; Premedication; Systemic Inf

2003
Systemic inflammatory response syndrome (SIRS) in serious chest injuries: is a pharmacological blockade effective?
    Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia, 2005, Volume: 11, Issue:4

    Topics: Adult; Aged; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studi

2005
[Blunt thoracic injury and the oxidation stress].
    Rozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti, 2006, Volume: 85, Issue:8

    Topics: Antioxidants; Cyclooxygenase Inhibitors; Humans; Indomethacin; Injury Severity Score; Oxidative Stre

2006
[SIRS and serious blunt thoracic injuries].
    Rozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti, 2006, Volume: 85, Issue:8

    Topics: Adult; Cyclooxygenase Inhibitors; Humans; Indomethacin; Injury Severity Score; Middle Aged; Respirat

2006
Evaluation of the analgesic effect of 0.1% indomethacin solution on corneal abrasions.
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 1999, Volume: 213, Issue:6

    Topics: Adult; Analgesia; Anti-Inflammatory Agents, Non-Steroidal; Cornea; Corneal Injuries; Eye Injuries; F

1999

Other Studies

2 other studies available for indomethacin and Blunt Injuries

ArticleYear
Isolated bilateral posterior scleritis after eye trauma.
    Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 2007, Volume: 11, Issue:3

    Topics: Azathioprine; Child; Conjunctiva; Drug Therapy, Combination; Eye Injuries; Eyelids; Female; Fluoresc

2007
Heterotopic ossification after blunt abdominal trauma.
    The Journal of trauma, 2008, Volume: 65, Issue:6

    Topics: Abdominal Injuries; Abdominal Wall; Accidents, Traffic; Adult; Anti-Inflammatory Agents, Non-Steroid

2008