indomethacin has been researched along with Blood Poisoning in 45 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The present study examined the effects of atorvastatin pretreatment on sepsis-induced endothelial dysfunctions and hypotension in rats." | 7.75 | Atorvastatin restores the impaired vascular endothelium-dependent relaxations mediated by nitric oxide and endothelium-derived hyperpolarizing factors but not hypotension in sepsis. ( Kathirvel, K; Kuntamallappanavar, G; Leo, MD; Mishra, SK; Subramani, J; Uttam Singh, T, 2009) |
| "In this research, the role of leptin on sepsis-induced organ dysfunction was evaluated." | 7.74 | Leptin protects vital organ functions after sepsis through recovering tissue myeloperoxidase activity: an anti-inflammatory role resonating with indomethacin. ( Hao, XH; Lin, J; Wang, LH; Xue, H; Yan, GT; Zhang, K, 2007) |
| "A preterm male infant with a patent ductus arteriosus developed neutropenia during treatment with indomethacin." | 7.73 | Indomethacin-associated neutropenia with subsequent Gram-negative sepsis in a preterm infant. Cause or coincidence? ( Bengtsson, BO; Milstein, JM; Sherman, MP, 2006) |
| "We investigated the effect of 16,16-dimethyl prostaglandin E2 indomethacin and Ginkgo biloba extract on the survival in two experimental sepsis models in rats due to administration of 1 x 10(7) cfu and 1 x 10(9) cfu Escherichia coli." | 7.70 | The effects of prostaglandin E2 indomethacin & Ginkgo biloba extract on resistance to experimental sepsis. ( Cantürk, NZ; Cantürk, Z; Dülger, M; Utkan, NZ; Yenisey, C; Yildirir, C, 1998) |
| "Sepsis was produced in piglets by bolus intravenous injection of 10(9) live Escherichia coli followed by an infusion of 10(9) E." | 5.27 | Indomethacin and the gastric mucosal blood flow changes of sepsis. ( Nilsson, LO; Stein, TA; Stone, AM; Wise, L, 1983) |
| " lingzhi and its autodigested product (AD-GL) against gut inflammation and endogenous sepsis induced in mice by the oral administration of indomethacin (IND)." | 3.88 | Protection against Gut Inflammation and Sepsis in Mice by the Autodigested Product of the Lingzhi Medicinal Mushroom, Ganoderma lingzhi (Agaricomycetes). ( Adachi, Y; Igami, K; Ishibashi, KI; Ishimoto, Y; Ito, H; Miyazaki, T; Ohno, N; Yamanaka, D, 2018) |
| " Magnesium sulfate administration, steroid administration, maternal diabetes mellitus, gestational age at delivery, indomethacin exposure, birthweight, and chorioamnionitis were all considered as possible covariates in the multivariable regression models." | 3.83 | Effect of obesity on neonatal outcomes in pregnancies with preterm premature rupture of membranes. ( DeWitt, PE; Faucett, AM; Gibbs, RS; Metz, TD, 2016) |
| " The present study examined the effects of atorvastatin pretreatment on sepsis-induced endothelial dysfunctions and hypotension in rats." | 3.75 | Atorvastatin restores the impaired vascular endothelium-dependent relaxations mediated by nitric oxide and endothelium-derived hyperpolarizing factors but not hypotension in sepsis. ( Kathirvel, K; Kuntamallappanavar, G; Leo, MD; Mishra, SK; Subramani, J; Uttam Singh, T, 2009) |
| "In this research, the role of leptin on sepsis-induced organ dysfunction was evaluated." | 3.74 | Leptin protects vital organ functions after sepsis through recovering tissue myeloperoxidase activity: an anti-inflammatory role resonating with indomethacin. ( Hao, XH; Lin, J; Wang, LH; Xue, H; Yan, GT; Zhang, K, 2007) |
| " In a phenylephrine-contracted canine carotid artery ring preparation, we found that both canine and human Lzm-S, at concentrations similar to those found in sepsis, produced vasorelaxation." | 3.74 | Lysozyme, a mediator of sepsis that produces vasodilation by hydrogen peroxide signaling in an arterial preparation. ( Bose, R; Cheng, ZQ; Jacobs, H; Kasian, K; Light, RB; Mink, SN; Santos Martinez, LE, 2008) |
| "A preterm male infant with a patent ductus arteriosus developed neutropenia during treatment with indomethacin." | 3.73 | Indomethacin-associated neutropenia with subsequent Gram-negative sepsis in a preterm infant. Cause or coincidence? ( Bengtsson, BO; Milstein, JM; Sherman, MP, 2006) |
| "We investigated the effect of 16,16-dimethyl prostaglandin E2 indomethacin and Ginkgo biloba extract on the survival in two experimental sepsis models in rats due to administration of 1 x 10(7) cfu and 1 x 10(9) cfu Escherichia coli." | 3.70 | The effects of prostaglandin E2 indomethacin & Ginkgo biloba extract on resistance to experimental sepsis. ( Cantürk, NZ; Cantürk, Z; Dülger, M; Utkan, NZ; Yenisey, C; Yildirir, C, 1998) |
| "Preterm infants with exposure to antenatal indomethacin might be at increased risk of grade I and II intraventricular haemorrhage and those with both ante- and postnatal exposure at an increased risk of necrotising enterocolitis and sepsis." | 3.70 | Perinatal indomethacin treatment and neonatal complications in preterm infants. ( Ikonen, S; Ojala, R; Tammela, O, 2000) |
| " Recently, we documented a sepsis-related depression in concanavalin A (ConA)-induced T-cell proliferation and intracellular Ca2+ (Ca2+i) mobilization." | 3.69 | Role of Ca2+ in prostaglandin E2-induced T-lymphocyte proliferative suppression in sepsis. ( Ahmad, S; Choudhry, MA; Sayeed, MM, 1995) |
| " We studied the effect of combination interleukin 1 beta and indomethacin sodium therapy on macrophage hyperactivity and survival after sepsis in a murine burn model." | 3.68 | Modulation of macrophage hyperactivity improves survival in a burn-sepsis model. ( Collins, KH; Mannick, JA; O'Riordain, MG; Pilz, M; Rodrick, ML; Saporoschetz, IB, 1992) |
| " We tested the hypothesis that sustained sepsis in rats results in relative hyporesponsiveness to the pressor actions of NE and angiotensin II (AII)." | 3.67 | Diminished pressor response to exogenous norepinephrine and angiotensin II in septic, unanesthetized rats: evidence for a prostaglandin-mediated effect. ( Fink, MP; Fletcher, JR; Homer, LD, 1985) |
| "Sepsis is characterized by a systemic inflammatory response syndrome." | 1.43 | Design, Synthesis, and Structure-Activity Relationship Study of Novel Indole-2-carboxamide Derivatives as Anti-inflammatory Agents for the Treatment of Sepsis. ( Feng, J; Gu, Y; Liang, G; Liu, Z; Qiu, C; Tang, L; Xu, T; Zhang, Y; Zheng, S; Zhu, H, 2016) |
| "Pretreatment with indomethacin and N-(G)-nitro-L-arginine methyl ester did not prevent gentamicin-induced DA relaxation." | 1.40 | Aminoglycoside-mediated relaxation of the ductus arteriosus in sepsis-associated PDA. ( Brown, N; Clark, RH; Cotton, RB; Ehinger, NJ; Goettel, JA; Paria, BC; Poole, SD; Reese, J; Rojas, MA; Shelton, EL; Slaughter, JC; Vucovich, MM; Wynn, JL, 2014) |
| "Sepsis was induced in rats by implanting fecal pellets containing Escherichia coli (150 CFU) and Bacteroides fragilis (10(4) CFU) into the abdominal cavity." | 1.30 | Prostaglandin E2 modulation of p59fyn tyrosine kinase in T lymphocytes during sepsis. ( Choudhry, MA; Sayeed, MM; Uddin, S, 1998) |
| "Sepsis was induced in 225-250 g male rats (Sprague Dawley) by implanting fecal pellets containing Escherichia coli (100-150 CFU) and Bacteroides fragilis (10(4) CFU) into the abdominal cavity." | 1.30 | Prostaglandin E2 down-regulation of T cell IL-2 production is independent of IL-10 during gram-negative sepsis. ( Ahmad, S; Ahmed, Z; Choudhry, MA; Sayeed, MM, 1999) |
| "Sepsis was induced by cecal ligation and puncture (CLP)." | 1.29 | Alterations of ex vivo vascular reactivity in intraperitoneal sepsis. ( Chen, SJ; Wu, CC; Yen, MH, 1994) |
| "Sepsis was produced in piglets by bolus intravenous injection of 10(9) live Escherichia coli followed by an infusion of 10(9) E." | 1.27 | Indomethacin and the gastric mucosal blood flow changes of sepsis. ( Nilsson, LO; Stein, TA; Stone, AM; Wise, L, 1983) |
| "Dazoxiben blocked the increase in plasma TXB2, prevented pulmonary hypertension, and attenuated the increase in EVLW after E." | 1.27 | Indomethacin, dazoxiben and extravascular lung water after Escherichia coli infusion. ( Carrico, CJ; Harlan, J; Hildebrandt, J; Price, S; Winn, R, 1986) |
| "Treatment with indomethacin prevented the 1-2 degrees C increase in body temperature observed in septic animals." | 1.27 | Fever is not responsible for the elevated glucose kinetics in sepsis. ( Bagby, GJ; Blakesley, HL; Lang, CH; Spitzer, JJ, 1987) |
| "When indomethacin was added in vitro, release of PGE2 by septic muscles and by normal muscles incubated in the presence of septic plasma was reduced by about 50%, but the increased proteolytic rate in these muscles was not affected." | 1.27 | Effect of indomethacin on proteolysis in septic muscle. ( Fischer, JE; Hasselgren, PO; James, JH; LaFrance, R; Peters, JC; Talamini, M, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (24.44) | 18.7374 |
| 1990's | 12 (26.67) | 18.2507 |
| 2000's | 11 (24.44) | 29.6817 |
| 2010's | 11 (24.44) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Özdemir, A | 1 |
| Altintop, MD | 1 |
| Turan-Zitouni, G | 1 |
| Çiftçi, GA | 1 |
| Ertorun, İ | 1 |
| Alataş, Ö | 1 |
| Kaplancikli, ZA | 1 |
| Liu, Z | 1 |
| Tang, L | 1 |
| Zhu, H | 1 |
| Xu, T | 1 |
| Qiu, C | 1 |
| Zheng, S | 1 |
| Gu, Y | 1 |
| Feng, J | 1 |
| Zhang, Y | 1 |
| Liang, G | 1 |
| Singh, G | 2 |
| Bhatti, R | 1 |
| Gupta, M | 1 |
| Kumar, A | 1 |
| Sharma, A | 1 |
| Singh Ishar, MP | 1 |
| Ishimoto, Y | 1 |
| Ishibashi, KI | 1 |
| Yamanaka, D | 1 |
| Adachi, Y | 2 |
| Ito, H | 1 |
| Igami, K | 1 |
| Miyazaki, T | 1 |
| Ohno, N | 2 |
| Rasooli, A | 1 |
| Fatemi, F | 1 |
| Hajihosseini, R | 1 |
| Vaziri, A | 1 |
| Akbarzadeh, K | 1 |
| Mohammadi Malayeri, MR | 1 |
| Dini, S | 1 |
| Foroutanrad, M | 1 |
| Ernst, W | 1 |
| Zimara, N | 1 |
| Hanses, F | 1 |
| Männel, DN | 1 |
| Seelbach-Göbel, B | 1 |
| Wege, AK | 1 |
| Vucovich, MM | 1 |
| Cotton, RB | 1 |
| Shelton, EL | 1 |
| Goettel, JA | 1 |
| Ehinger, NJ | 1 |
| Poole, SD | 1 |
| Brown, N | 1 |
| Wynn, JL | 1 |
| Paria, BC | 1 |
| Slaughter, JC | 1 |
| Clark, RH | 1 |
| Rojas, MA | 1 |
| Reese, J | 1 |
| Faucett, AM | 1 |
| Metz, TD | 1 |
| DeWitt, PE | 1 |
| Gibbs, RS | 1 |
| Saito, M | 1 |
| Nameda, S | 1 |
| Miura, NN | 1 |
| Nögel, SC | 1 |
| Chada, M | 1 |
| Schmidt, AM | 1 |
| Bosselmann, S | 1 |
| Kandler, M | 1 |
| Schweer, H | 1 |
| Watzer, B | 1 |
| Schneider, H | 1 |
| Gessner, A | 1 |
| Rascher, W | 1 |
| Subramani, J | 1 |
| Kathirvel, K | 1 |
| Leo, MD | 1 |
| Kuntamallappanavar, G | 1 |
| Uttam Singh, T | 1 |
| Mishra, SK | 1 |
| Sallmon, H | 1 |
| Weber, SC | 1 |
| Hüning, B | 1 |
| Stein, A | 1 |
| Horn, PA | 1 |
| Metze, BC | 1 |
| Dame, C | 1 |
| Bührer, C | 1 |
| Felderhoff-Müser, U | 1 |
| Hansmann, G | 1 |
| Koehne, P | 1 |
| Davis, JS | 1 |
| Ryan, ML | 1 |
| Shields, JM | 1 |
| Sola, JE | 1 |
| Perez, EA | 1 |
| Neville, HL | 1 |
| Rodriguez, MM | 1 |
| Chiang, PJ | 1 |
| Hsu, JF | 1 |
| Tsai, MH | 1 |
| Lien, R | 1 |
| Chiang, MC | 1 |
| Huang, HR | 1 |
| Chiang, CC | 1 |
| Liang, HF | 1 |
| Chu, SM | 1 |
| García-Herrera, J | 1 |
| Navarro, MA | 1 |
| Marca, MC | 1 |
| de la Osada, J | 1 |
| Rodríguez-Yoldi, MJ | 1 |
| Osterberg, J | 1 |
| Ljungdahl, M | 1 |
| Haglund, U | 1 |
| Bengtsson, BO | 1 |
| Milstein, JM | 1 |
| Sherman, MP | 1 |
| Patole, SK | 1 |
| Kumaran, V | 1 |
| Travadi, JN | 1 |
| Brooks, JM | 1 |
| Doherty, DA | 1 |
| Lin, J | 1 |
| Yan, GT | 1 |
| Xue, H | 1 |
| Hao, XH | 1 |
| Zhang, K | 1 |
| Wang, LH | 1 |
| Mink, SN | 1 |
| Kasian, K | 1 |
| Santos Martinez, LE | 1 |
| Jacobs, H | 1 |
| Bose, R | 1 |
| Cheng, ZQ | 1 |
| Light, RB | 1 |
| Short, BL | 1 |
| Miller, MK | 1 |
| Stroud, CY | 1 |
| Fletcher, JR | 3 |
| Nilsson, LO | 1 |
| Stone, AM | 1 |
| Stein, TA | 1 |
| Wise, L | 1 |
| Fink, MP | 2 |
| MacVittie, TJ | 1 |
| Casey, LC | 1 |
| Chen, SJ | 1 |
| Wu, CC | 1 |
| Yen, MH | 1 |
| Choudhry, MA | 3 |
| Ahmad, S | 2 |
| Sayeed, MM | 3 |
| Wang, P | 1 |
| Ba, ZF | 1 |
| Chaudry, IH | 1 |
| Cisneros, RL | 1 |
| Gibson, FC | 1 |
| Tzianabos, AO | 1 |
| Rudinsky, BF | 1 |
| Lozon, M | 2 |
| Bell, A | 2 |
| Hipps, R | 2 |
| Meadow, WL | 1 |
| Uddin, S | 1 |
| Cantürk, NZ | 1 |
| Utkan, NZ | 1 |
| Cantürk, Z | 1 |
| Yenisey, C | 1 |
| Yildirir, C | 1 |
| Dülger, M | 1 |
| Magder, S | 1 |
| Rastepagarnah, M | 1 |
| Ahmed, Z | 1 |
| Ojala, R | 1 |
| Ikonen, S | 1 |
| Tammela, O | 1 |
| Rudinsky, B | 1 |
| Meadow, W | 1 |
| O'Riordain, MG | 1 |
| Collins, KH | 1 |
| Pilz, M | 1 |
| Saporoschetz, IB | 1 |
| Mannick, JA | 1 |
| Rodrick, ML | 1 |
| Hasselgren, PO | 2 |
| Zamir, O | 1 |
| James, JH | 2 |
| Fischer, JE | 2 |
| Rasmussen, LT | 1 |
| Fandrem, J | 1 |
| Seljelid, R | 1 |
| Price, S | 1 |
| Harlan, J | 1 |
| Carrico, CJ | 1 |
| Hildebrandt, J | 1 |
| Winn, R | 1 |
| Lang, CH | 1 |
| Bagby, GJ | 1 |
| Blakesley, HL | 1 |
| Spitzer, JJ | 1 |
| Choudhary, G | 1 |
| Sharma, MP | 1 |
| Homer, LD | 1 |
| Talamini, M | 1 |
| LaFrance, R | 1 |
| Peters, JC | 1 |
| Arturson, G | 1 |
| Kent, TH | 1 |
| Cardelli, RM | 1 |
| Stamler, FW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Liberal Versus Restrictive Platelet Transfusion for Treatment of Hemodynamically Significant Patent Ductus Arteriosus in Thrombocytopenic Preterm Neonates- A Randomized Open Label, Controlled Trial[NCT03022253] | Phase 3 | 44 participants (Anticipated) | Interventional | 2016-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for indomethacin and Blood Poisoning
| Article | Year |
|---|---|
Segmental absence of intestinal musculature: an increasingly reported pathology.
Topics: Abdomen, Acute; Abnormalities, Multiple; Adult; Cesarean Section; Digestive System Abnormalities; Du | 2012 |
Burn shock.
Topics: Animals; Blood Circulation; Burns; Capillary Permeability; Catecholamines; Dextrans; Dogs; Edema; He | 1974 |
43 other studies available for indomethacin and Blood Poisoning
| Article | Year |
|---|---|
Synthesis and evaluation of new indole-based chalcones as potential antiinflammatory agents.
Topics: Animals; Cell Survival; Chalcones; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Di | 2015 |
Design, Synthesis, and Structure-Activity Relationship Study of Novel Indole-2-carboxamide Derivatives as Anti-inflammatory Agents for the Treatment of Sepsis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Drug Design; Ind | 2016 |
Indolyl-isoxazolidines attenuate LPS-stimulated pro-inflammatory cytokines and increase survival in a mouse model of sepsis: Identification of potent lead.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Disease Models, Animal; Inflammation; Interleukin-6; | 2018 |
Protection against Gut Inflammation and Sepsis in Mice by the Autodigested Product of the Lingzhi Medicinal Mushroom, Ganoderma lingzhi (Agaricomycetes).
Topics: Animals; beta-Glucans; Cells, Cultured; Cytokines; Fungal Polysaccharides; Gastrointestinal Diseases | 2018 |
Synergistic effects of deuterium depleted water and Mentha longifolia L. essential oils on sepsis-induced liver injuries through regulation of cyclooxygenase-2.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Cyclooxygenase 2; Deuterium; Disease Models, Animal | 2019 |
Humanized mice, a new model to study the influence of drug treatment on neonatal sepsis.
Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bacterial Load; Betamethason | 2013 |
Aminoglycoside-mediated relaxation of the ductus arteriosus in sepsis-associated PDA.
Topics: Animals; Chemokine CXCL12; Ductus Arteriosus; Ductus Arteriosus, Patent; Gentamicins; Humans; In Vit | 2014 |
Effect of obesity on neonatal outcomes in pregnancies with preterm premature rupture of membranes.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Birth Weight; Case-Control Studies; Cerebral Hemorrhage; | 2016 |
Effect of SPG/indomethacin treatment on sepsis, interleukin-6 production, and expression of hepatic cytochrome P450 isoforms in differing strains of mice.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Cytochrome P-450 CYP2E1; Cytochrome P-45 | 2009 |
Parecoxib does not suppress thromboxane synthesis in newborn piglets with group B streptococcal sepsis.
Topics: Animals; Animals, Newborn; Cyclooxygenase 2 Inhibitors; Dinoprostone; Epoprostenol; Gene Expression | 2009 |
Atorvastatin restores the impaired vascular endothelium-dependent relaxations mediated by nitric oxide and endothelium-derived hyperpolarizing factors but not hypotension in sepsis.
Topics: Acetylcholine; Animals; Aorta; Atorvastatin; Biological Factors; Blood Cell Count; Blood Pressure; C | 2009 |
Thrombocytopenia in the first 24 hours after birth and incidence of patent ductus arteriosus.
Topics: Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Echocardiography, Doppler; Female; Humans; Ibu | 2012 |
The impact of patent ductus arteriosus in neonates with late onset sepsis: a retrospective matched-case control study.
Topics: Age Factors; Bronchopulmonary Dysplasia; Case-Control Studies; Databases, Factual; Ductus Arteriosus | 2012 |
The effect of tumor necrosis factor-alpha on D-fructose intestinal transport in rabbits.
Topics: Animals; Biological Transport; Enterocytes; Enzyme Inhibitors; Fructose; Glucose Transporter Type 5; | 2004 |
Influence of cyclooxygenase inhibitors on gut immune cell distribution and apoptosis rate in experimental sepsis.
Topics: Animals; Apoptosis; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Disease Models, A | 2006 |
Indomethacin-associated neutropenia with subsequent Gram-negative sepsis in a preterm infant. Cause or coincidence?
Topics: Cardiovascular Agents; Ductus Arteriosus, Patent; Enterobacter cloacae; Enterobacteriaceae Infection | 2006 |
Does patent ductus arteriosus affect feed tolerance in preterm neonates?
Topics: Age Factors; Analysis of Variance; Cardiovascular Agents; Ductus Arteriosus, Patent; Enteral Nutriti | 2007 |
Leptin protects vital organ functions after sepsis through recovering tissue myeloperoxidase activity: an anti-inflammatory role resonating with indomethacin.
Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Indomethacin; Kidney; Leptin | 2007 |
Lysozyme, a mediator of sepsis that produces vasodilation by hydrogen peroxide signaling in an arterial preparation.
Topics: Aminoquinolines; Animals; Carotid Artery, Internal; Catalase; Cyclic GMP; Cyclic GMP-Dependent Prote | 2008 |
Comparison of thromboxane inhibitors to cyclooxygenase inhibitors on survival in a newborn rat model for group B streptococcal sepsis.
Topics: Animals; Animals, Newborn; Ibuprofen; Indomethacin; Rats; Rats, Inbred Strains; Sepsis; Streptococca | 1983 |
Indomethacin and the gastric mucosal blood flow changes of sepsis.
Topics: Animals; Escherichia coli Infections; Gastric Mucosa; Indomethacin; Sepsis; Swine | 1983 |
Inhibition of prostaglandin synthesis restores normal hemodynamics in canine hyperdynamic sepsis.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Disease Models, Animal; Dogs; Escherichia coli Infections; Fe | 1984 |
The role of prostaglandins in sepsis.
Topics: Animals; Escherichia coli Infections; Indomethacin; Male; Prostaglandin Antagonists; Prostaglandins; | 1982 |
Alterations of ex vivo vascular reactivity in intraperitoneal sepsis.
Topics: Animals; Arginine; Blood Glucose; Blood Pressure; Body Temperature; Cecum; Disease Models, Animal; D | 1994 |
Role of Ca2+ in prostaglandin E2-induced T-lymphocyte proliferative suppression in sepsis.
Topics: Animals; Calcium; Concanavalin A; Dinoprostone; Indomethacin; Lymphocyte Activation; Male; Rats; Rat | 1995 |
Nitric oxide. To block or enhance its production during sepsis?
Topics: Acetylcholine; Animals; Aorta, Thoracic; In Vitro Techniques; Indomethacin; Male; Nitric Oxide; Nitr | 1994 |
Passive transfer of poly-(1-6)-beta-glucotriosyl-(1-3)-beta-glucopyranose glucan protection against lethal infection in an animal model of intra-abdominal sepsis.
Topics: Adjuvants, Immunologic; Animals; beta-Glucans; Dinoprostone; Glucans; Immunotherapy, Adoptive; Indom | 1996 |
Group B streptococcal sepsis impairs cerebral vascular reactivity to acute hypercarbia in piglets.
Topics: Animals; Blood Pressure; Brain; Carbon Monoxide; Carotid Artery, Internal; Disease Models, Animal; H | 1996 |
Prostaglandin E2 modulation of p59fyn tyrosine kinase in T lymphocytes during sepsis.
Topics: Animals; Bacteroides fragilis; Bacteroides Infections; Dinoprostone; Enzyme Activation; Escherichia | 1998 |
The effects of prostaglandin E2 indomethacin & Ginkgo biloba extract on resistance to experimental sepsis.
Topics: Animals; Cyclooxygenase Inhibitors; Dinoprostone; Ginkgo biloba; Indomethacin; Male; Oxytocics; Phyt | 1998 |
Role of neurosympathetic pathways in the vascular response to sepsis.
Topics: Adaptation, Physiological; Animals; Cyclooxygenase Inhibitors; Denervation; Disease Models, Animal; | 1998 |
Prostaglandin E2 down-regulation of T cell IL-2 production is independent of IL-10 during gram-negative sepsis.
Topics: Animals; Bacteroides fragilis; Bacteroides Infections; Dinoprostone; Disease Models, Animal; Down-Re | 1999 |
Perinatal indomethacin treatment and neonatal complications in preterm infants.
Topics: Cerebral Hemorrhage; Enterocolitis, Necrotizing; Female; Humans; Indomethacin; Infant, Newborn; Infa | 2000 |
Hemodynamic homeostasis during acute hypoxia in septic and nonseptic piglets: differential role of prostaglandins and nitric oxide.
Topics: Animals; Arginine; Hemodynamics; Homeostasis; Hypoxia; Indomethacin; Nitric Oxide; Prostaglandin Ant | 2000 |
Modulation of macrophage hyperactivity improves survival in a burn-sepsis model.
Topics: Animals; Burns; Indomethacin; Interleukin-1; Interleukin-6; Macrophages; Male; Mice; Mice, Inbred A; | 1992 |
Prostaglandin E2 does not regulate total or myofibrillar protein breakdown in incubated skeletal muscle from normal or septic rats.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cycloheximide; Dinoprostone; In Vitro Techniques; Indo | 1990 |
Dynamics of blood components and peritoneal fluid during treatment of murine E. coli sepsis with beta-1,3-D-polyglucose derivatives. II. Interleukin 1, tumour necrosis factor, prostaglandin E2, and leukotriene B4.
Topics: Animals; Arachidonic Acids; Ascitic Fluid; beta-Glucans; Cytokines; Dinoprostone; Escherichia coli I | 1990 |
Indomethacin, dazoxiben and extravascular lung water after Escherichia coli infusion.
Topics: Animals; Body Water; Cyclooxygenase Inhibitors; Escherichia coli Infections; Female; Imidazoles; Ind | 1986 |
Fever is not responsible for the elevated glucose kinetics in sepsis.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blood Glucose; Blood Pressure; Cyclooxygenase Inhibito | 1987 |
Septicaemia: newer mode of therapy.
Topics: Adrenal Cortex Hormones; Blood Transfusion; Humans; Immunization, Passive; Indomethacin; Naloxone; S | 1987 |
Diminished pressor response to exogenous norepinephrine and angiotensin II in septic, unanesthetized rats: evidence for a prostaglandin-mediated effect.
Topics: Analysis of Variance; Angiotensin II; Animals; Blood Pressure; Dose-Response Relationship, Drug; Ele | 1985 |
Effect of indomethacin on proteolysis in septic muscle.
Topics: Amino Acids; Animals; Indomethacin; Male; Muscle Proteins; Muscles; Peptide Hydrolases; Prostaglandi | 1985 |
Small intestinal ulcers and intestinal flora in rats given indomethacin.
Topics: Animals; Anti-Bacterial Agents; Cecal Diseases; Ileum; Indomethacin; Intestinal Diseases; Intestine, | 1969 |