indomethacin has been researched along with Blood Clot in 44 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The long-term administration of captopril to patients with a left ventricular dysfunction after myocardial infarction reduces the rate of recurrent coronary thrombosis." | 7.70 | Nitric oxide and prostacyclin are involved in antithrombotic action of captopril in venous thrombosis in rats. ( Azzadin, A; Buczko, W; Chabielska, E; Golatowski, J; Pawlak, R, 1998) |
| "Propionyl carnitine can prevent endothelin and carrageenin-induced thrombosis in the rat's tail." | 7.68 | Thrombosis induced by endothelin (ET-1) and carrageenin in rats treated with indomethacin and propionyl carnitine. ( Bertelli, A; Bertelli, AA; Galmozzi, G; Giovannini, L; Mian, M, 1993) |
| "In an antithrombin-III (AT-III) deficient patient suffering from recurrent episodes of venous and arterial thrombosis requiring major surgery an attempt was made to institute antithrombotic protection by long-term stanozolol treatment supplemented during periods of thrombogenic exposure with subcutaneous heparin and, when needed, infusion of AT-III as plasma or concentrate." | 7.67 | Protection against venous thrombosis in an antithrombin-III deficient patient suffering from episodes of arterial thrombosis requiring major surgery. Effects of oral stanozolol in combination with subcutaneous heparin and intravenous AT-III. ( Astrup, T; Gram, J; Jespersen, J; Kluft, C, 1985) |
| " Using the photothrombosis model in adult rats, focal ischemic infarcts were induced in different cortical areas (sensorimotor forelimb and hindlimb cortex) and proliferating cells were labeled at days 3-14 after infarct induction with bromodeoxyuridine." | 3.73 | Neurogenesis in the adult dentate gyrus after cortical infarcts: effects of infarct location, N-methyl-D-aspartate receptor blockade and anti-inflammatory treatment. ( Bolz, J; Kluska, MM; Redecker, C; Witte, OW, 2005) |
| "The long-term administration of captopril to patients with a left ventricular dysfunction after myocardial infarction reduces the rate of recurrent coronary thrombosis." | 3.70 | Nitric oxide and prostacyclin are involved in antithrombotic action of captopril in venous thrombosis in rats. ( Azzadin, A; Buczko, W; Chabielska, E; Golatowski, J; Pawlak, R, 1998) |
| "LMWH (Fraxiparine), and NSAIDs (Aspirin, Feldene, Indocid and Profenid) injected together in doses, 1 mg/kg (Aspirin was used at 100 mg/kg), subcutaneously into rats 30 minutes before the thrombosis induction by LASER beams, increased the number of LASER beams required to induce platelet thrombus formation, decreased the number of emboli and reduced the duration of embolization, compared with control (p < or = 0." | 3.69 | Effect of the low molecular weight heparin/non steroidal anti-inflammatory drugs association on an experimental thrombosis induced by laser. ( Aguejouf, O; Doutremepuich, C; Doutremepuich, F; Imbault, P; Oualane, FA, 1995) |
| "5 U/g) and indomethacin (200 micrograms/g) had no significant effect in prolonging the occlusion time or in reducing ADP-induced pulmonary embolism in mice." | 3.69 | In vivo antithrombotic effect of triflavin, an Arg-Gly-Asp containing peptide on platelet plug formation in mesenteric microvessels of mice. ( Chao, SH; Huang, TF; Sheu, JR; Yen, MH, 1994) |
| "Propionyl carnitine can prevent endothelin and carrageenin-induced thrombosis in the rat's tail." | 3.68 | Thrombosis induced by endothelin (ET-1) and carrageenin in rats treated with indomethacin and propionyl carnitine. ( Bertelli, A; Bertelli, AA; Galmozzi, G; Giovannini, L; Mian, M, 1993) |
| "Arterial platelet thrombosis was induced in vivo in a branch of the mesenteric artery of the white Wistar rat by topical superfusion by adenosine diphosphate following local de-endothelialization of the dissected segment by means of a small electrical current." | 3.67 | The effect of inhibition of endothelial cell cyclooxygenase on arterial thrombosis. ( Andries, R; Bourgain, RH; Braquet, P; Deby, C, 1985) |
| " Capsaicin was effective in preventing death caused by ADP-induced acute pulmonary thromboembolism in mice at dose of 25 mg/kg, while aspirin and indomethacin had no effect at 200 mg/kg." | 3.67 | Antihemostatic and antithrombotic effects of capsaicin in comparison with aspirin and indomethacin. ( Hsu, MF; Hsu, TP; Teng, CM; Wang, JP, 1985) |
| "In an antithrombin-III (AT-III) deficient patient suffering from recurrent episodes of venous and arterial thrombosis requiring major surgery an attempt was made to institute antithrombotic protection by long-term stanozolol treatment supplemented during periods of thrombogenic exposure with subcutaneous heparin and, when needed, infusion of AT-III as plasma or concentrate." | 3.67 | Protection against venous thrombosis in an antithrombin-III deficient patient suffering from episodes of arterial thrombosis requiring major surgery. Effects of oral stanozolol in combination with subcutaneous heparin and intravenous AT-III. ( Astrup, T; Gram, J; Jespersen, J; Kluft, C, 1985) |
| "Erythromelalgia was localized in the forefoot sole and toes in 28, the fingertips in 9, the handpalm in 2." | 2.39 | Erythromelalgic, thrombotic and hemorrhagic manifestations in 50 cases of thrombocythemia. ( Lindemans, J; Michiels, JJ; van Genderen, PJ; van Vliet, HH, 1996) |
| "Dissolution of the thrombus local catheter-directed intra-arterial infusion of fibrinolytic agents such as urokinase is the standard therapy for thrombosis; however, this method is time-intensive, and amputation of the affected limb is still needed in 10-30% of cases." | 1.40 | Contrast-enhanced sonothrombolysis in a porcine model of acute peripheral arterial thrombosis and prevention of anaphylactic shock. ( Meyer, KW; Musters, RJ; Nederhoed, JH; Slikkerveer, J; Wisselink, W; Yeung, KK, 2014) |
| "Since diffuse microthrombosis has been implicated as a potential etiology for organ dysfunction and failure in sepsis, the present study examined the production of procoagulant activity (PCA) by M phi in response to endotoxin, characterized the activity, and evaluated methods to modify the response." | 1.27 | Microthrombosis during endotoxemia: potential role of hepatic versus alveolar macrophages. ( Hahnel, GB; Maier, RV, 1984) |
| "The "stable thrombus" was sensitive to indomethacin, and was not inhibited by PGI2, when applied after the formation, whereas the "ADP-induced thrombus" was sensitive to PGI2, but insensitive to indomethacin." | 1.27 | Roles of arachidonate metabolites in thrombus formation and leukocyte migration: analyses at microcirculatory level. ( Hirose, R; Katori, M; Nagai, K; Sasaki, K, 1987) |
| "Erythromelalgia was the presenting symptom in 26 of 40 patients with thrombocythemia in its primary form or when associated with polycythemia vera." | 1.27 | Erythromelalgia caused by platelet-mediated arteriolar inflammation and thrombosis in thrombocythemia. ( Abels, J; Michiels, JJ; Steketee, J; van Vliet, HH; Vuzevski, VD, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 26 (59.09) | 18.7374 |
| 1990's | 12 (27.27) | 18.2507 |
| 2000's | 3 (6.82) | 29.6817 |
| 2010's | 3 (6.82) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nederhoed, JH | 1 |
| Slikkerveer, J | 1 |
| Meyer, KW | 1 |
| Wisselink, W | 1 |
| Musters, RJ | 1 |
| Yeung, KK | 1 |
| Duzhyĭ, ID | 1 |
| Kravets', OV | 1 |
| Hres'ko, IIa | 1 |
| Iurchenko, AV | 1 |
| Miyoshi, T | 1 |
| Ikeda, T | 1 |
| Yoshimatsu, J | 1 |
| Ikeda, Y | 1 |
| Ishibashi-Ueda, H | 1 |
| Kluska, MM | 1 |
| Witte, OW | 1 |
| Bolz, J | 1 |
| Redecker, C | 1 |
| Eizayaga, FX | 1 |
| Aguejouf, O | 2 |
| Desplat, V | 1 |
| Belon, P | 1 |
| Doutremepuich, C | 2 |
| Mogielnicki, A | 1 |
| Kramkowski, K | 1 |
| Pietrzak, L | 1 |
| Buczko, W | 2 |
| Hansen, MS | 1 |
| Birgens, HS | 1 |
| Packham, MA | 1 |
| Mustard, JF | 1 |
| Maier, RV | 1 |
| Hahnel, GB | 1 |
| Ohtsu, A | 1 |
| Oba, T | 1 |
| Kamimoto, F | 1 |
| Wada, H | 1 |
| Hoshina, K | 1 |
| Saitoh, N | 1 |
| Okada, N | 1 |
| Yamazaki, N | 1 |
| Kurozumi, S | 1 |
| Naruchi, T | 1 |
| Chernukh, AM | 1 |
| Entsik, LA | 1 |
| Gomazkov, OA | 1 |
| Bygdeman, M | 1 |
| Helenski, C | 1 |
| Schaub, RG | 1 |
| Roberts, R | 1 |
| Yokota, K | 1 |
| Yamashita, A | 1 |
| Oda, M | 1 |
| Nygård, G | 1 |
| Hudson, M | 1 |
| Mazure, G | 1 |
| Anthony, A | 1 |
| Dhillon, AP | 1 |
| Pounder, RE | 1 |
| Wakefield, AJ | 1 |
| Doutremepuich, F | 1 |
| Imbault, P | 1 |
| Oualane, FA | 1 |
| Sheu, JR | 1 |
| Chao, SH | 1 |
| Yen, MH | 1 |
| Huang, TF | 1 |
| Bertelli, A | 1 |
| Bertelli, AA | 1 |
| Galmozzi, G | 1 |
| Giovannini, L | 1 |
| Mian, M | 1 |
| Shindo, M | 1 |
| Majima, M | 1 |
| Ohno, T | 1 |
| Sugimoto, K | 1 |
| Ohwada, T | 1 |
| Michiels, JJ | 2 |
| van Genderen, PJ | 1 |
| Lindemans, J | 1 |
| van Vliet, HH | 2 |
| Pawlak, R | 1 |
| Chabielska, E | 1 |
| Golatowski, J | 1 |
| Azzadin, A | 1 |
| Monnink, SH | 1 |
| van Boven, AJ | 1 |
| Peels, HO | 1 |
| Tigchelaar, I | 1 |
| de Kam, PJ | 1 |
| Crijns, HJ | 1 |
| van Oeveren, W | 1 |
| Brecht, T | 1 |
| Jobin, F | 1 |
| Fregnan, GB | 1 |
| Chieli, T | 1 |
| Rockwell, WB | 1 |
| Ehrlich, HP | 1 |
| Korbut, R | 1 |
| Ocetkiewicz, A | 1 |
| Dabros, W | 1 |
| Gryglewski, RJ | 1 |
| Bourgain, RH | 2 |
| Andries, R | 2 |
| Braquet, P | 2 |
| Knahr, K | 1 |
| Salzer, M | 1 |
| Eyb, R | 1 |
| Frank, P | 1 |
| Blauensteiner, W | 1 |
| Katori, M | 2 |
| Hirose, R | 2 |
| Tanaka, K | 1 |
| Hyman, PE | 1 |
| Abrams, CE | 1 |
| Zipser, RD | 1 |
| Sasaki, K | 1 |
| Nagai, K | 1 |
| Smith, EF | 1 |
| Olson, RW | 1 |
| Deby, C | 1 |
| Abels, J | 1 |
| Steketee, J | 1 |
| Vuzevski, VD | 1 |
| Wang, JP | 2 |
| Hsu, MF | 2 |
| Hsu, TP | 1 |
| Teng, CM | 1 |
| Jespersen, J | 1 |
| Gram, J | 1 |
| Kluft, C | 1 |
| Astrup, T | 1 |
| Huang, LJ | 1 |
| Kovács, IB | 1 |
| Görög, P | 1 |
| Silver, MJ | 1 |
| Smith, JB | 1 |
| Ingerman, CM | 1 |
| Sanjo, T | 1 |
| Ono, S | 1 |
| Bologna, E | 1 |
| Surana, RB | 1 |
| Scott, RB | 1 |
| Ferguson, AD | 1 |
| Gaspardy, G | 1 |
| Balint, G | 1 |
3 reviews available for indomethacin and Blood Clot
| Article | Year |
|---|---|
Pharmacology of platelet-affecting drugs.
Topics: Animals; Arachidonic Acids; Arteriosclerosis; Aspirin; Blood Platelets; Cyclic AMP; Dose-Response Re | 1980 |
Erythromelalgic, thrombotic and hemorrhagic manifestations in 50 cases of thrombocythemia.
Topics: Adult; Aged; Aspirin; Busulfan; Double-Blind Method; Erythromelalgia; Female; Gangrene; Hemorrhage; | 1996 |
[Treatment of chronic glomerulonephritis with non-steroidal anti-inflammatory agents].
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Chronic Disease; Depression, Chemical; Female; Gl | 1974 |
41 other studies available for indomethacin and Blood Clot
| Article | Year |
|---|---|
Contrast-enhanced sonothrombolysis in a porcine model of acute peripheral arterial thrombosis and prevention of anaphylactic shock.
Topics: Anaphylaxis; Animals; Cardiovascular Agents; Contrast Media; Female; Indomethacin; Lipids; Mechanica | 2014 |
[Prophylaxis of thrombohemorrhagic complications in surgical treatment of chemoresistant pulmonary tuberculosis].
Topics: Adult; Anticoagulants; Antitubercular Agents; Female; Hemorrhage; Humans; Hydroxyethylrutoside; Indo | 2014 |
Fetal pulmonary thrombosis.
Topics: Adult; Chylothorax; Dilatation, Pathologic; Fatal Outcome; Female; Fetal Distress; Humans; Hydrops F | 2013 |
Neurogenesis in the adult dentate gyrus after cortical infarcts: effects of infarct location, N-methyl-D-aspartate receptor blockade and anti-inflammatory treatment.
Topics: Animals; Anti-Inflammatory Agents; Antimetabolites; Bromodeoxyuridine; Cell Survival; Cerebral Infar | 2005 |
Modifications produced by indomethacin and L-NAME in the effect of ultralow-dose aspirin on platelet activity in portal hypertension.
Topics: Animals; Aspirin; Blood Coagulation Tests; Cyclooxygenase Inhibitors; Disease Models, Animal; Drug I | 2006 |
N-methylnicotinamide inhibits arterial thrombosis in hypertensive rats.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Flow Velocity; Blood Pressure; Carotid Arteries; Collag | 2007 |
[Prevention of thrombosis by thrombocyte inhibitors. 1. Cell regulation mechanisms and pharmacological modification].
Topics: Adenosine Diphosphate; Aspirin; Blood Platelets; Cyclic AMP; Dextrans; Dipyridamole; Humans; Hydroxy | 1980 |
Microthrombosis during endotoxemia: potential role of hepatic versus alveolar macrophages.
Topics: Adrenal Cortex Hormones; Animals; Blood Coagulation; Endotoxins; Factor VII; Indomethacin; Lipopolys | 1984 |
Effects of a novel acylindole derivative on experimental thrombotic models, ulceration of the gastric mucosa and prostacyclin production in the aorta.
Topics: Animals; Aorta; Arteriovenous Shunt, Surgical; Blood Platelets; Epoprostenol; Fibrinolytic Agents; G | 1981 |
[Effect of aspirin, indomethacin and imidazole on thrombus formation at the site of a vascular wall injury by a laser ray].
Topics: Animals; Aspirin; Dose-Response Relationship, Drug; Imidazoles; Indomethacin; Lasers; Male; Mesenter | 1981 |
Clinical applications.
Topics: Abortion, Induced; Aspirin; Blood Pressure; Cardiovascular Diseases; Cervix Uteri; Digestive System; | 1980 |
Improvement of collateral circulation after arterial thrombosis with indomethacin therapy.
Topics: Animals; Aortic Diseases; Aortography; Blood Coagulation; Cats; Collateral Circulation; Fibrin; Indo | 1980 |
Anti-thrombotic activity of KBT-3022 in experimental models of thrombosis.
Topics: Animals; Arachidonic Acid; Aspirin; Cyclooxygenase Inhibitors; Extracorporeal Circulation; Guinea Pi | 1995 |
Procoagulant and prothrombotic responses of human endothelium to indomethacin and endotoxin in vitro. Relevance to non-steroidal anti-inflammatory drug enteropathy.
Topics: 6-Ketoprostaglandin F1 alpha; Anti-Inflammatory Agents, Non-Steroidal; Blood Coagulation Factors; Ce | 1995 |
Effect of the low molecular weight heparin/non steroidal anti-inflammatory drugs association on an experimental thrombosis induced by laser.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Drug Therapy, Combination; Indomethacin; | 1995 |
In vivo antithrombotic effect of triflavin, an Arg-Gly-Asp containing peptide on platelet plug formation in mesenteric microvessels of mice.
Topics: Acute Disease; Adenosine Diphosphate; Alprostadil; Amino Acid Sequence; Animals; Blood Pressure; End | 1994 |
Thrombosis induced by endothelin (ET-1) and carrageenin in rats treated with indomethacin and propionyl carnitine.
Topics: Animals; Cardiotonic Agents; Carnitine; Carrageenan; Eicosanoids; Endothelins; Indomethacin; Male; R | 1993 |
Induction mechanism of small intestinal lesions caused by intravenous injection of endotoxin in rats.
Topics: Animals; Capillary Leak Syndrome; Cyclooxygenase Inhibitors; Endotoxins; Enzyme Inhibitors; Epoprost | 1996 |
Nitric oxide and prostacyclin are involved in antithrombotic action of captopril in venous thrombosis in rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Cyclooxygenase Inhibit | 1998 |
Silicon-carbide coated coronary stents have low platelet and leukocyte adhesion during platelet activation.
Topics: Blood Platelets; Carbon Compounds, Inorganic; Cell Adhesion; Coated Materials, Biocompatible; Corona | 1999 |
[Conservative treatment of venous diseases in the practice without anticoagulants and fibrinolytic drugs].
Topics: Bandages; Dihydroergotamine; Humans; Indomethacin; Physical Exertion; Thrombosis; Varicose Veins | 1977 |
[Platelet-inhibiting drugs].
Topics: Anti-Bacterial Agents; Aspirin; Dextrans; Dipyridamole; Hemorrhage; Humans; Indomethacin; Platelet A | 1978 |
The effect of a new anti-inflammatory agent, the ethoxy methyl ester of N-(2,6-dichloro-m-tolyl)-anthranilic acid (A3), on platelet behaviour "in vivo" and "in vitro".
Topics: Administration, Oral; Administration, Topical; Animals; Anti-Inflammatory Agents; Arterial Occlusive | 1975 |
An ibuprofen-antagonized plasmin inhibitor released by human endothelial cells.
Topics: Antifibrinolytic Agents; Burns; Cells, Cultured; Cicatrix; Endothelium; Fibrinolysis; Hot Temperatur | 1991 |
A biological method for studying the interaction between platelets and vascular endothelium.
Topics: Animals; Aorta, Thoracic; Arteriosclerosis; Aspirin; Blood Platelets; Endothelium, Vascular; Epopros | 1990 |
Endotoxin, PAF and arterial thrombosis.
Topics: Animals; Endotoxins; Epoprostenol; Guinea Pigs; Indomethacin; Male; Mesenteric Vascular Occlusion; P | 1990 |
Heterotopic ossification with total hip endoprostheses in various models of thrombosis prophylaxis.
Topics: Aspirin; Bone and Bones; Choristoma; Dextrans; Heparin; Hip Prosthesis; Humans; Indomethacin; Oxyphe | 1988 |
Differences in sensitivities of platelet thrombi to indomethacin and prostacyclin in arterioles of hamster cheek pouch.
Topics: Animals; Arteries; Arterioles; Cheek; Cricetinae; Indomethacin; Mouth Mucosa; Platelet Aggregation; | 1985 |
Enhanced urinary immunoreactive thromboxane in neonatal necrotizing enterocolitis. A diagnostic indicator of thrombotic activity.
Topics: beta-Thromboglobulin; Enterocolitis, Pseudomembranous; Humans; Indomethacin; Infant, Newborn; Infant | 1987 |
Roles of arachidonate metabolites in thrombus formation and leukocyte migration: analyses at microcirculatory level.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acids; Cell Adhesion; Cell Movement; Cheek; Cricetinae; | 1987 |
Synergism between a phosphodiesterase inhibitor and modulators of thromboxane formation on thrombin-induced sudden death in rabbits.
Topics: Animals; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Death, Sudden; Drug Synergism; Fat | 1987 |
The effect of inhibition of endothelial cell cyclooxygenase on arterial thrombosis.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Cyclooxygenase | 1985 |
Erythromelalgia caused by platelet-mediated arteriolar inflammation and thrombosis in thrombocythemia.
Topics: Adult; Aged; Analgesics; Arteries; Arterioles; Arteritis; Aspirin; Blood Platelets; Erythromelalgia; | 1985 |
Antihemostatic and antithrombotic effects of capsaicin in comparison with aspirin and indomethacin.
Topics: Adenosine Diphosphate; Animals; Aspirin; Blood Coagulation; Capsaicin; Hemostasis; Indomethacin; Mic | 1985 |
Protection against venous thrombosis in an antithrombin-III deficient patient suffering from episodes of arterial thrombosis requiring major surgery. Effects of oral stanozolol in combination with subcutaneous heparin and intravenous AT-III.
Topics: Administration, Oral; Adult; Amputation, Surgical; Antithrombin III; Antithrombin III Deficiency; Dr | 1985 |
Antihemostatic and antithrombotic effects of XC386.
Topics: Animals; Aspirin; Blood Coagulation; Hematocrit; Heparin; Indomethacin; Mice; Platelet Aggregation; | 1985 |
The effect of anti-inflammatory drugs on the aggregation and adhesiveness of platelets, red cells and leukocytes.
Topics: Adenosine Diphosphate; Aminosalicylic Acids; Animals; Anti-Inflammatory Agents; Antigen-Antibody Com | 1972 |
Blood platelets and the inflammatory process.
Topics: Aspirin; Blood Platelets; Blood Proteins; Capillary Permeability; Hemostasis; Histamine; Humans; Ind | 1974 |
Influence of some drugs on platelet aggregation: a study in hypertensive patients.
Topics: Adenosine Diphosphate; Anti-Inflammatory Agents; Aspirin; Benzyl Compounds; Blood Cell Count; Blood | 1972 |
Studies in sickle-cell anemia. XXXI. Preliminary observations on the use of indomethacin in the treatment of thrombotic crises.
Topics: Adolescent; Anemia, Sickle Cell; Black or African American; Child; Edema; Female; Humans; Indomethac | 1966 |
[Personal results with indomethacin treatment].
Topics: Indomethacin; Rheumatic Fever; Thrombosis | 1967 |