Page last updated: 2024-10-29

indomethacin and Bilirubinemia

indomethacin has been researched along with Bilirubinemia in 6 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Research Excerpts

ExcerptRelevanceReference
" In addition, characterization of the UGT1A locus and genetic studies directed at understanding the role of bilirubin glucuronidation and the biochemical basis of the clinical symptoms found in unconjugated hyperbilirubinemia have uncovered the structural gene polymorphisms associated with Crigler-Najjar's and Gilbert's syndrome."4.80Human UDP-glucuronosyltransferases: metabolism, expression, and disease. ( Strassburg, CP; Tukey, RH, 2000)
"The neurologic manifestations of neonatal hyperbilirubinemia in the central nervous system (CNS) exhibit high variations in the severity and appearance of motor, auditory and cognitive symptoms, which is suggestive of a still unexplained selective topography of bilirubin-induced damage."3.85Evaluation of region selective bilirubin-induced brain damage as a basis for a pharmacological treatment. ( Bottin, C; Dal Ben, M; Gazzin, S; Tiribelli, C; Zanconati, F, 2017)
"This report deals with three cases of Bartter's syndrome whose symptomatology was associated with indirect hyperbilirubinemia."1.28Bartter's syndrome associated with indirect hyperbilirubinemia: a possible clinical variety. ( Battisti, P; Cugini, P; Di Palma, L; Di Simone, S; Kawasaki, T; Sasaki, H; Uezono, K, 1990)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's1 (16.67)18.2507
2000's3 (50.00)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tukey, RH1
Strassburg, CP1
Dal Ben, M1
Bottin, C1
Zanconati, F1
Tiribelli, C1
Gazzin, S1
Rheinlaender, C1
Helfenstein, D1
Walch, E1
Berns, M1
Obladen, M1
Koehne, P1
Hansen, TW1
Bischof, P1
Kaiser, H1
Cugini, P1
Sasaki, H1
Kawasaki, T1
Di Simone, S1
Di Palma, L1
Battisti, P1
Uezono, K1

Reviews

1 review available for indomethacin and Bilirubinemia

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia;

2000

Other Studies

5 other studies available for indomethacin and Bilirubinemia

ArticleYear
Evaluation of region selective bilirubin-induced brain damage as a basis for a pharmacological treatment.
    Scientific reports, 2017, 01-19, Volume: 7

    Topics: Animals; Bilirubin; Brain; Brain Diseases, Metabolic; Cell Survival; Curcumin; Encephalitis; Hyperbi

2017
Total serum bilirubin levels during cyclooxygenase inhibitor treatment for patent ductus arteriosus in preterm infants.
    Acta paediatrica (Oslo, Norway : 1992), 2009, Volume: 98, Issue:1

    Topics: Bilirubin; Child, Preschool; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Female; Hemodynam

2009
Ibuprofen for closure of patent ductus arteriosus: is it really safe in hyperbilirubinaemic infants?
    European journal of pediatrics, 2003, Volume: 162, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Ductus Arteriosus, Patent; Humans; Hyperbilirubinemia; Ibup

2003
[Problems of rheumatism therapy in pregnant women].
    Verhandlungen der Deutschen Gesellschaft fur Rheumatologie, 1978, Volume: 5

    Topics: Abortion, Spontaneous; Chloroquine; Female; Gold; Humans; Hyperbilirubinemia; Indomethacin; Penicill

1978
Bartter's syndrome associated with indirect hyperbilirubinemia: a possible clinical variety.
    Endocrinologia japonica, 1990, Volume: 37, Issue:1

    Topics: Adult; Aldosterone; Bartter Syndrome; Chlorides; Female; Humans; Hydrocortisone; Hyperaldosteronism;

1990