indomethacin has been researched along with Biliary Cirrhosis in 9 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We present an infrequent case of acute hepatitis by indomethacin, in a patient with a primary biliary cirrhosis, previously not diagnosed and asymptomatic, in who during in the follow-up, with a persistent analytical pattern of disociated cholestasis, a liver biopsy was indicated, with the final diagnosis of chronic non-suppurative destructive cholangitis." | 7.69 | [Acute ++indomethacin-induced hepatitis in a female patient with asymptomatic primary biliary cirrhosis]. ( Alvarez Navascues, C; González González, M; González Sotorrio, N; Rodrigo Sáez, L; Rodríguez García, M; Suárez González, A, 1994) |
| "We evaluated the effect of ursodeoxycholic acid on the defective natural killer activity in primary biliary cirrhosis." | 7.69 | Ursodeoxycholic acid corrects defective natural killer activity by inhibiting prostaglandin E2 production in primary biliary cirrhosis. ( Moriwaki, H; Muto, Y; Nishigaki, Y; Ohnishi, H, 1996) |
| "We present an infrequent case of acute hepatitis by indomethacin, in a patient with a primary biliary cirrhosis, previously not diagnosed and asymptomatic, in who during in the follow-up, with a persistent analytical pattern of disociated cholestasis, a liver biopsy was indicated, with the final diagnosis of chronic non-suppurative destructive cholangitis." | 3.69 | [Acute ++indomethacin-induced hepatitis in a female patient with asymptomatic primary biliary cirrhosis]. ( Alvarez Navascues, C; González González, M; González Sotorrio, N; Rodrigo Sáez, L; Rodríguez García, M; Suárez González, A, 1994) |
| "We evaluated the effect of ursodeoxycholic acid on the defective natural killer activity in primary biliary cirrhosis." | 3.69 | Ursodeoxycholic acid corrects defective natural killer activity by inhibiting prostaglandin E2 production in primary biliary cirrhosis. ( Moriwaki, H; Muto, Y; Nishigaki, Y; Ohnishi, H, 1996) |
| " Dose-response curves, the hemodynamic effects of prostacyclin (20 micrograms/kg) and its inhibitor indomethacin and measurements of plasma and urinary levels of 6-keto-prostaglandin F1 alpha were compared in three groups of six rats each: normal, with portal vein stenosis and with secondary biliary cirrhosis." | 3.68 | Role of prostacyclin in hemodynamic alterations in conscious rats with extrahepatic or intrahepatic portal hypertension. ( Cailmail, S; Lebrec, D; Moreau, R; Oberti, F; Pipy, B; Sogni, P, 1993) |
| "In a previous study we observed that after in vitro treatment with indomethacin, lymphocyte response to phytohaemagglutinin (PHA) in primary biliary cirrhosis (PBC) patients was higher than that of controls." | 3.67 | Immune dysfunction in primary biliary cirrhosis. II. Increased production of prostaglandin E. ( Bartolini, G; Bianchi, F; Chiricolo, M; Franceschi, C; Lenzi, M; Licastro, F; Orlandi, M; Tomasi, V, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (44.44) | 18.7374 |
| 1990's | 4 (44.44) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Levy, M | 1 |
| Wexler, MJ | 1 |
| Fechner, C | 1 |
| Holdstock, G | 1 |
| Chastenay, BF | 1 |
| Krawitt, EL | 1 |
| Suárez González, A | 1 |
| Rodríguez García, M | 1 |
| González González, M | 1 |
| Alvarez Navascues, C | 1 |
| González Sotorrio, N | 1 |
| Rodrigo Sáez, L | 1 |
| Oberti, F | 1 |
| Sogni, P | 1 |
| Cailmail, S | 1 |
| Moreau, R | 1 |
| Pipy, B | 1 |
| Lebrec, D | 1 |
| Nishigaki, Y | 1 |
| Ohnishi, H | 1 |
| Moriwaki, H | 1 |
| Muto, Y | 1 |
| Criado, M | 2 |
| Flores, O | 2 |
| Hidalgo, F | 1 |
| López-Novoa, JM | 1 |
| Sánchez-Rodríguez, A | 1 |
| Vázquez, MJ | 1 |
| Esteller, A | 1 |
| Chiricolo, M | 2 |
| Lenzi, M | 2 |
| Bianchi, F | 2 |
| Franceschi, C | 2 |
| Bartolini, G | 1 |
| Orlandi, M | 1 |
| Tomasi, V | 1 |
| Licastro, F | 2 |
| Davis, LJ | 1 |
| Cassani, F | 1 |
9 other studies available for indomethacin and Biliary Cirrhosis
| Article | Year |
|---|---|
Renal perfusion in dogs with experimental hepatic cirrhosis: role of prostaglandins.
Topics: Animals; Bile Ducts; Captopril; Cholecystectomy; Dogs; Female; Glomerular Filtration Rate; Imidazole | 1983 |
Studies on lymphocyte hyporesponsiveness in cirrhosis: the role of increased monocyte suppressor cell activity.
Topics: Adult; Aged; Hepatitis; Humans; Indomethacin; Liver Cirrhosis; Liver Cirrhosis, Alcoholic; Liver Cir | 1982 |
[Acute ++indomethacin-induced hepatitis in a female patient with asymptomatic primary biliary cirrhosis].
Topics: Acute Disease; Chemical and Drug Induced Liver Injury; Female; Humans; Indomethacin; Liver Cirrhosis | 1994 |
Role of prostacyclin in hemodynamic alterations in conscious rats with extrahepatic or intrahepatic portal hypertension.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Pressure; Cardiac Output; Common Bile Duct; Dose-Respon | 1993 |
Ursodeoxycholic acid corrects defective natural killer activity by inhibiting prostaglandin E2 production in primary biliary cirrhosis.
Topics: Adult; Aged; Cells, Cultured; Chenodeoxycholic Acid; Cholic Acid; Cholic Acids; Chronic Disease; Deo | 1996 |
Interaction between prostanoids and nitric oxide in the control of tubular function in rats with chronic bile duct ligation.
Topics: Animals; Blood Pressure; Body Weight; Cyclooxygenase Inhibitors; Female; Heart Rate; Indomethacin; K | 1999 |
Role of prostanoids and nitric oxide inhibition in rats with experimental hepatic fibrosis.
Topics: Animals; Blood Pressure; Body Weight; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Female; Heart Ra | 2000 |
Immune dysfunction in primary biliary cirrhosis. II. Increased production of prostaglandin E.
Topics: Humans; Indomethacin; Liver Cirrhosis, Biliary; Lymphocyte Activation; Middle Aged; Prostaglandins E | 1989 |
Immune dysfunction in primary biliary cirrhosis (PBC): I. Increased sensitivity of PHA stimulated lymphocyte cultures to indomethacin.
Topics: Adult; Aged; Female; Humans; In Vitro Techniques; Indomethacin; Liver Cirrhosis, Biliary; Lymphocyte | 1987 |