indomethacin has been researched along with Auditory Processing Disorder, Central in 2 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Luu, TM | 2 |
| Ment, LR | 2 |
| Schneider, KC | 2 |
| Katz, KH | 2 |
| Allan, WC | 2 |
| Vohr, BR | 2 |
| Tucker, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomized Indomethacin Germinal Matrix Hemorrhage/Intraventricular Hemorrhage (GMH/IVH) Prevention Trial[NCT00033917] | Phase 3 | 630 participants (Actual) | Interventional | 1989-09-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Cranial ultrasounds were performed daily for the first 5 postnatal days; the main outcome measure was intraaventricular hemorrhage (IVH) at 5 days of age (NCT00033917)
Timeframe: at 5 days
| Intervention | IVH (Number) |
|---|---|
| Indomethacin | 25 |
| Placebo | 40 |
"Peabody Picture Vocabulary Test (PPVT) This is a semantic language test. The mean value is 100; standard deviation is 16 points. A higher score means better language; a lower score means poorer language.~There are no subscales to the PPVT. The measurement unit is points on a scale. A score < 70 indicates severely abnormal language function." (NCT00033917)
Timeframe: at 8 years
| Intervention | participants with PPVT score < 70 (Number) |
|---|---|
| Indomethacin - no IVH | 12 |
| Indomethacin - IVH | 5 |
| Placebo - no IVH | 24 |
| Placebo - IVH | 7 |
2 trials available for indomethacin and Auditory Processing Disorder, Central
| Article | Year |
|---|---|
Lasting effects of preterm birth and neonatal brain hemorrhage at 12 years of age.
Topics: Brain Damage, Chronic; Cerebral Ventricles; Child; Child Behavior Disorders; Child, Preschool; Cogni | 2009 |
Trajectories of receptive language development from 3 to 12 years of age for very preterm children.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Brain Damage, Chronic; Cerebral Hemorrhage; Child; Child, P | 2009 |