Page last updated: 2024-10-29

indomethacin and Atrophy

indomethacin has been researched along with Atrophy in 10 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Atrophy: Decrease in the size of a cell, tissue, organ, or multiple organs, associated with a variety of pathological conditions such as abnormal cellular changes, ischemia, malnutrition, or hormonal changes.

Research Excerpts

ExcerptRelevanceReference
"Results of these studies demonstrate that provision of additional NO substrate in the form of L-arginine incites prostaglandin-dependent secretory diarrhea and does not promote epithelial defense or barrier function of C."7.74Oral delivery of L-arginine stimulates prostaglandin-dependent secretory diarrhea in Cryptosporidium parvum-infected neonatal piglets. ( Coccaro, MR; Foster, DM; Gookin, JL; Stauffer, SH, 2008)
"We report a case of reversible acute renal failure associated with indomethacin therapy."5.27Reversible acute interstitial nephritis associated with indomethacin. ( Barzilai, D; Better, OS; Green, J; Yoffe, B, 1985)
"Results of these studies demonstrate that provision of additional NO substrate in the form of L-arginine incites prostaglandin-dependent secretory diarrhea and does not promote epithelial defense or barrier function of C."3.74Oral delivery of L-arginine stimulates prostaglandin-dependent secretory diarrhea in Cryptosporidium parvum-infected neonatal piglets. ( Coccaro, MR; Foster, DM; Gookin, JL; Stauffer, SH, 2008)
" Indomethacin induced gastritis but without atrophy, and short-term vitamin deficiency failed to induce chronic gastritis and gastric atrophy."3.72Chronic gastritis rat model and role of inducing factors. ( Huang, HD; Si, JM; Xiang, Z, 2004)
" Therapeutic levels of aspirin in vivo had a similar adverse effect on degenerating cartilage, as noted in two canine models of osteoarthritis and cartilage atrophy."3.67Effects of salicylates and other nonsteroidal anti-inflammatory drugs on articular cartilage. ( Brandt, KD; Palmoski, MJ, 1984)
"We report a case of reversible acute renal failure associated with indomethacin therapy."1.27Reversible acute interstitial nephritis associated with indomethacin. ( Barzilai, D; Better, OS; Green, J; Yoffe, B, 1985)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19904 (40.00)18.7374
1990's0 (0.00)18.2507
2000's4 (40.00)29.6817
2010's1 (10.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Tanaka, S1
Nemoto, Y1
Takei, Y1
Morikawa, R1
Oshima, S1
Nagaishi, T1
Okamoto, R1
Tsuchiya, K1
Nakamura, T1
Stutte, S1
Watanabe, M1
Yamamoto, A1
Itoh, T1
Nasu, R1
Nishida, R1
Straube, A1
Linn, J1
Xiang, Z2
Si, JM1
Huang, HD1
Gookin, JL1
Foster, DM1
Coccaro, MR1
Stauffer, SH1
Brandt, KD2
Palmoski, MJ2
Si, J1
Zhou, W1
Wu, J1
Cao, Q1
Jiang, L1
Lü, W1
Huang, H1
Green, J1
Yoffe, B1
Barzilai, D1
Better, OS1
Ofuji, T1
Takahara, J1
Ogawa, N1
Miyoshi, M1

Other Studies

10 other studies available for indomethacin and Atrophy

ArticleYear
High-fat diet-derived free fatty acids impair the intestinal immune system and increase sensitivity to intestinal epithelial damage.
    Biochemical and biophysical research communications, 2020, 02-19, Volume: 522, Issue:4

    Topics: Animals; Atrophy; Colon; Diet, High-Fat; Fatty Acids, Nonesterified; Feeding Behavior; Gastrointesti

2020
Sodium alginate ameliorates indomethacin-induced gastrointestinal mucosal injury via inhibiting translocation in rats.
    World journal of gastroenterology, 2014, Mar-14, Volume: 20, Issue:10

    Topics: Alginates; Anemia; Animals; Anti-Ulcer Agents; Atrophy; Bacterial Translocation; Biomarkers; Capilla

2014
Unilateral headache attacks and ipsilateral atrophy of the tongue due to neurovascular compression of the hypoglossal nerve.
    Cephalalgia : an international journal of headache, 2008, Volume: 28, Issue:9

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Atrophy; Carotid Stenosis; Headache; Humans; Hypoglossal Ne

2008
Chronic gastritis rat model and role of inducing factors.
    World journal of gastroenterology, 2004, Nov-01, Volume: 10, Issue:21

    Topics: Alcohols; Ammonia; Animals; Anti-Inflammatory Agents, Non-Steroidal; Atrophy; Chronic Disease; Deoxy

2004
Oral delivery of L-arginine stimulates prostaglandin-dependent secretory diarrhea in Cryptosporidium parvum-infected neonatal piglets.
    Journal of pediatric gastroenterology and nutrition, 2008, Volume: 46, Issue:2

    Topics: Alanine; Analysis of Variance; Animals; Animals, Newborn; Arginine; Atrophy; Chlorides; Cryptosporid

2008
Effects of salicylates and other nonsteroidal anti-inflammatory drugs on articular cartilage.
    The American journal of medicine, 1984, Jul-13, Volume: 77, Issue:1A

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Atrophy; Cartilage, Articular; Dogs; Extracellular Matri

1984
Establishment of an animal model of chronic atrophic gastritis and a study on the factors inducing atrophy.
    Chinese medical journal, 2001, Volume: 114, Issue:12

    Topics: Ammonia; Animals; Atrophy; Deoxycholic Acid; Disease Models, Animal; Ethanol; Gastric Mucosa; Gastri

2001
Proteoglycan depletion, rather than fibrillation, determines the effects of salicylate and indomethacin on osteoarthritic cartilage.
    Arthritis and rheumatism, 1985, Volume: 28, Issue:5

    Topics: Animals; Atrophy; Cartilage, Articular; Culture Techniques; Dogs; Glycosaminoglycans; Indomethacin;

1985
Reversible acute interstitial nephritis associated with indomethacin.
    Israel journal of medical sciences, 1985, Volume: 21, Issue:2

    Topics: Acute Kidney Injury; Atrophy; Female; Glomerular Mesangium; Humans; Indomethacin; Kidney Tubules; Mi

1985
[Anétodermie urticarienne--a case report].
    Saishin igaku. Modern medicine, 1969, Volume: 24, Issue:11

    Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adult; Atrophy; Female; Humans; Indomethacin; Pituitary-Ad

1969