Page last updated: 2024-10-29

indomethacin and Atopic Hypersensitivity

indomethacin has been researched along with Atopic Hypersensitivity in 12 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Research Excerpts

ExcerptRelevanceReference
" Allergen (Southern Grass Mix) was administered intradermally 2 h after last drug dosage and the surface areas of the immediate wheal-and-flare-reactions were measured 15 min later."2.67Effect of enalapril on allergen-induced cutaneous hypersensitivity reaction. ( Snyman, JR; Sommers, DK, 1991)
"Chlorpheniramine pretreatment prevented death, delayed the onset of respiratory symptoms and decreased the severity of the hypersensitivity reaction."1.27Use of a simple in vivo technique to investigate components of the immediate hypersensitivity reaction in conscious guinea pigs. ( Hammerbeck, DM; Swingle, KF, 1984)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19908 (66.67)18.7374
1990's3 (25.00)18.2507
2000's1 (8.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Plaut, M1
Marone, G1
Thomas, LL1
Lichtenstein, LM1
Cavaillon, JM1
Dandeu, JP1
MĂ©cheri, S1
David, B1
Hammerbeck, DM1
Swingle, KF1
StrannegÄrd, IL1
Hall, TJ1
Hudspith, BN1
Brostoff, J1
Di Pierro, F1
d'Atri, G1
Marcucci, F1
Leoni, F1
Saarinen, JV1
Harvima, RJ1
Horsmanheimo, M1
Harvima, IT1
Snyman, JR1
Sommers, DK1
Sladek, K1
Sheller, JR1
FitzGerald, GA1
Morrow, JD1
Roberts, LJ1
Abraham, WM1
Stevenson, JS1
Garrido, R1
Baird, AW1
Cuthbert, AW1
Pearce, FL1
Smolin, G1
Keates, RH1

Trials

2 trials available for indomethacin and Atopic Hypersensitivity

ArticleYear
Modulation of the immediate allergic wheal reaction in the skin by drugs inhibiting the effects of leukotriene C4 and prostaglandin D2.
    European journal of clinical pharmacology, 2001, Volume: 57, Issue:1

    Topics: Administration, Cutaneous; Adolescent; Adult; Allergens; Animals; Anti-Allergic Agents; Cattle; Cycl

2001
Effect of enalapril on allergen-induced cutaneous hypersensitivity reaction.
    British journal of clinical pharmacology, 1991, Volume: 32, Issue:6

    Topics: Administration, Oral; Adult; Allergens; Enalapril; Female; Humans; Hypersensitivity, Immediate; Indo

1991

Other Studies

10 other studies available for indomethacin and Atopic Hypersensitivity

ArticleYear
Cyclic nucleotides in immune responses and allergy.
    Advances in cyclic nucleotide research, 1980, Volume: 12

    Topics: Adenosine; Animals; Antigens; Basophils; Cyclic AMP; Histamine Release; Humans; Hypersensitivity, Im

1980
Presence of IL 1 activity in the supernatant of human monocytes challenged with purified allergenic constituents.
    International archives of allergy and applied immunology, 1984, Volume: 75, Issue:2

    Topics: Animals; Antibodies, Monoclonal; Complement System Proteins; Humans; Hypersensitivity, Immediate; In

1984
Use of a simple in vivo technique to investigate components of the immediate hypersensitivity reaction in conscious guinea pigs.
    International archives of allergy and applied immunology, 1984, Volume: 74, Issue:1

    Topics: Aerosols; Anaphylaxis; Animals; Atropine; Bronchial Spasm; Chlorpheniramine; Chromones; Guinea Pigs;

1984
Adherent suppressor cells in atopic disease.
    International archives of allergy and applied immunology, 1981, Volume: 64, Issue:3

    Topics: Adolescent; Cell Adhesion; Child; Child, Preschool; Humans; Hypersensitivity, Immediate; Indomethaci

1981
The role of prostaglandins in the modulation of histamine suppression of mitogen responses in atopic and normal subjects.
    International journal of immunopharmacology, 1983, Volume: 5, Issue:2

    Topics: Adolescent; Adult; Concanavalin A; Histamine; Humans; Hypersensitivity, Immediate; Indomethacin; Lym

1983
Use of type I and type IV hypersensitivity responses to define the immunopharmacological profile of drugs.
    Journal of pharmacological and toxicological methods, 1997, Volume: 37, Issue:2

    Topics: Animals; C-Reactive Protein; Cyclosporine; Drug Evaluation, Preclinical; Female; Hypersensitivity, D

1997
Formation of PGD2 after allergen inhalation in atopic asthmatics.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1991, Volume: 21A

    Topics: Allergens; Asthma; Cyclooxygenase Inhibitors; Double-Blind Method; Forced Expiratory Volume; Hyperse

1991
A possible role for PAF in allergen-induced late responses: modification by a selective antagonist.
    Journal of applied physiology (Bethesda, Md. : 1985), 1989, Volume: 66, Issue:5

    Topics: Aerosols; Allergens; Animals; Antigens, Helminth; Ascaris; Asthma; Azepines; Chlorpheniramine; Chrom

1989
Immediate hypersensitivity reactions in epithelia from rats infected with Nippostrongylus brasiliensis.
    British journal of pharmacology, 1985, Volume: 85, Issue:4

    Topics: Animals; Chlorides; Chromones; Colon; Cromolyn Sodium; Electric Conductivity; Epithelium; Hypersensi

1985
Suppression of the corneal hypersensitivity reaction.
    American journal of ophthalmology, 1967, Volume: 63, Issue:2

    Topics: Aminocaproates; Animals; Antigen-Antibody Reactions; Arthus Reaction; Cornea; Hypersensitivity, Dela

1967