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indomethacin and Asthma, Bronchial

indomethacin has been researched along with Asthma, Bronchial in 142 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Research Excerpts

ExcerptRelevanceReference
"We sought to determine the effect of inhaled indomethacin on asthma control and asthma exacerbations during reduction of inhaled corticosteroids in patients with moderate-to-severe steroid-dependent asthma."9.09Effect of inhaled indomethacin in asthmatic patients taking high doses of inhaled corticosteroids. ( Aoshiba, K; Kawatani, K; Kondo, M; Nagai, A; Nakata, J; Nishimura, K; Tamaoki, J, 2000)
"Little is known about the anti-asthmatic effects of powerful anti-inflammatory agents such as aspirin-like drugs."9.09Different effects of inhaled aspirinlike drugs on allergen-induced early and late asthmatic responses. ( Bianco, S; Pieroni, MG; Refini, RM; Robuschi, M; Sestini, P; Vaghi, A, 1999)
"We evaluated the effect of inhaled indomethacin, a nonsteroidal antiinflammatory drug (NSAID), against bronchoconstriction induced by ultrasonically nebulized distilled water (UNDW) in children with asthma."9.08Inhaled indomethacin prevents bronchoconstrictive response to distilled water but not to histamine in children with asthma. ( Kuroume, T; Maeda, S; Mochizuki, H; Morikawa, A; Shigeta, M; Shimizu, T, 1995)
"day-1 for 4 days), on cough response to inhaled capsaicin were examined in eight patients with asthma, 10 patients with chronic bronchitis, and 10 normal subjects."9.08Prostanoids and cough response to capsaicin in asthma and chronic bronchitis. ( Bando, T; Fujimura, M; Hashimoto, T; Kamio, Y; Kasahara, K; Matsuda, T, 1995)
"These results suggest an important role of cyclooxygenase pathway products in decreased response to repeated inhalation of acetaldehyde in patients with asthma."9.08Inhibitory effect of indomethacin on tachyphylaxis in response to acetaldehyde-induced bronchoconstriction in patients with asthma. ( Fujimura, M; Kamio, Y; Matsuda, T; Myou, S, 1997)
"The effect of indomethacin on the capacity of LTE4 to enhance airway histamine responsiveness was evaluated in eight mild asthmatic subjects."9.07Effect of indomethacin on leukotriene4-induced histamine hyperresponsiveness in asthmatic subjects. ( Christie, PE; Hawksworth, R; Lee, TH; Spur, BW, 1992)
" To investigate whether prostaglandin production could also modulate the bronchial antireactive activity of this diuretic drug, we investigated the effect of inhaled lysine acetylsalicylate (162 mg) and of furosemide (18 mg), alone and in combination, on the bronchial obstructive response to ultrasonically nebulized water in asthmatic patients."9.07Potentiation of the antireactive, antiasthmatic effect of inhaled furosemide by inhaled lysine acetylsalicylate. ( Berni, F; Bianco, S; Pieroni, MG; Refini, RM; Robuschi, M; Sestini, P; Vaghi, A, 1993)
"The present investigation was designed to evaluate the effects of pre-treatment with the cholinergic muscarinic receptor antagonist, atropine sulfate, or with the cyclooxygenase inhibitor, indomethacin, on adenosine-induced bronchoconstriction in human asthmatics."9.06Adenosine-induced bronchoconstriction in human asthmatics: effects of pretreatment with indomethacin or atropine sulfate. ( Diamond, L; Küng, M, 1990)
"We have examined the effects of indomethacin (I) on tolerance to the bronchomotor effects of repetitive challenge with exercise (EX) and eucapnic hyperpnea (EH) in 7 asthmatic subjects."9.06Indomethacin blocks airway tolerance to repetitive exercise but not to eucapnic hyperpnea in asthmatic subjects. ( Bigby, BG; Boushey, HA; Margolskee, DJ, 1988)
"Inhalation histamine challenges were performed in groups of normal and asthmatic subjects."9.05Prostaglandins and the control of airways responses to histamine in normal and asthmatic subjects. ( Walters, EH, 1983)
"The effect of specific antigen challenge on the lung function of eight allergic asthmatic patients after placebo and indomethacin pretreatment has been investigated."9.05Lung function and plasma levels of thromboxane B2, 6-ketoprostaglandin F1 alpha and beta-thromboglobulin in antigen-induced asthma before and after indomethacin pretreatment. ( Joubert, JR; Macfarlane, CM; Malan, L; Mouton, W; Shephard, EG, 1985)
" The cells were isolated from 3 groups of subjects: nonasthmatic patients (n = 10), patients with aspirin-tolerant asthma (ATA, n = 9), and patients with aspirin-intolerant asthma (AIA, n = 7)."7.72Deficient prostaglandin E2 production by bronchial fibroblasts of asthmatic patients, with special reference to aspirin-induced asthma. ( Pierzchalska, M; Sanak, M; Soja, J; Szabó, Z; Szczeklik, A, 2003)
"A life-threatening episode of bronchial asthma may follow treatment by ophthalmic indomethacin."7.69Acute bronchial asthma associated with the administration of ophthalmic indomethacin. ( Polachek, J; Shvartzman, P, 1996)
"Histamine release induced by platelet-activating factor (PAF) from leukocytes of aspirin-sensitive subjects with asthma was higher than that from normal control subjects, despite the similarity of anti-IgE-induced histamine release."7.68Basophil histamine release by platelet-activating factor in aspirin-sensitive subjects with asthma. ( Hattori, H; Kishimoto, S; Miyatake, A; Okuda, Y; Takashima, T; Tsuyuguchi, I; Yamatodani, A, 1990)
"The bronchoconstriction induced by repeated histamine inhalation tests was studied in eight mild stable asthmatic subjects to determine whether histamine tachyphylaxis occurs in asthmatics."7.67Tachyphylaxis to inhaled histamine in asthmatic subjects. ( Jones, GL; Manning, PJ; O'Byrne, PM, 1987)
"Twenty-nine patients with asthma and aspirin-sensitivity were studied in an attempt to induce tolerance to aspirin (ASA)."7.67Aspirin tolerance induced in aspirin-sensitive asthmatics. ( Grzelewska-Rzymowska, I; Kowalski, ML; Rozniecki, J; Szmidt, M, 1984)
"Aspirin-sensitive asthma is a common and severe disorder characterized by asthmatic attacks after oral ingestion of cyclooxygenase inhibiting drugs."7.67[Demonstration of specific platelet function anomaly in asthma induced by aspirin: diagnostic consequences]. ( Ameisen, JC; Capron, A; Fournier, E; Joseph, M; Pancré, V; Tonnel, AB; Vorng, H; Wallaert, B, 1985)
"Airway reactivity to histamine was determined in a group of non-asthmatic and asthmatic patients prior to thoracotomy."7.67Human isolated bronchial muscle preparations from asthmatic patients: effects of indomethacin and contractile agonists. ( Benveniste, J; Brink, C; Cerrina, J; Haye-Legrande, I; Labat, C; Raffestin, B, 1989)
"To examine the role of arachidonic acid metabolism in the modulation of immediate-type immunologic airway responses, we compared the effects of indomethacin (50 mg every 6 h for 96 h) and placebo on responses to antigen inhalation challenge in allergic asthmatic subjects and a group of nonasthmatic subjects with allergic rhinitis."7.66Indomethacin modification of immediate-type immunologic airway responses in allergic asthmatic and non-asthmatic subjects: evidence for altered arachidonic acid metabolism in asthma. ( Adkinson, NF; Ankin, MG; Fish, JE; Peterman, VI, 1981)
"In an attempt to elucidate the mechanisms involved in analgesic-induced asthma, I performed bronchial and intravenous challenge tests with indomethacin in 5 aspirin-sensitive asthmatics."7.66Bronchial and intravenous provocation tests with indomethacin in aspirin-sensitive asthmatics. ( Martelli, NA, 1979)
"We studied the effect of ascorbic acid in 14 mild asthmatic subjects."7.66Effect of ascorbic acid on response to methacholine challenge in asthmatic subjects. ( Douglas, JS; Dubois, AB; Mohsenin, V, 1983)
"Thirty aspirin-sensitive asthmatic patients underwent incremental, oral aspirin challenge until a "positive reaction" (delta FEV1 greater than or equal to 25%) occurred."7.66Aspirin desensitization in aspirin-sensitive asthmatic patients: clinical manifestations and characterization of the refractory period. ( Mathison, DA; Pleskow, WW; Schatz, M; Simon, RA; Stevenson, DD; Zeiger, RS, 1982)
" 9 The results are also discussed in relation to the genesis of aspirin-induced asthma in man."7.66Spontaneous activity in the trachea of dogs treated with indomethacin: an experimental model for aspirin-related asthma. ( Ito, Y; Tajima, K, 1981)
"Eleven patients with asthma and aspirin hypersensitivity have been challenged with eight non-steroidal anti-inflammatory drugs."7.65Relationship of inhibition of prostaglandin biosynthesis by analgesics to asthma attacks in aspirin-sensitive patients. ( Czerniawska-Mysik, G; Gryglewski, RJ; Szczeklik, A, 1975)
"Indomethacin has been used to demonstrate that cyclooxygenase (COX) metabolites of arachidonic acid play a mechanistic role in ozone-induced spirometric decline in normals (Nm)."5.31Cyclooxygenase metabolites play a different role in ozone-induced pulmonary function decline in asthmatics compared to normals. ( Alexis, N; Corey, P; O'Byrne, P; Pengelly, D; Silverman, F; Tarlo, S; Urch, B, 2000)
"We sought to determine the effect of inhaled indomethacin on asthma control and asthma exacerbations during reduction of inhaled corticosteroids in patients with moderate-to-severe steroid-dependent asthma."5.09Effect of inhaled indomethacin in asthmatic patients taking high doses of inhaled corticosteroids. ( Aoshiba, K; Kawatani, K; Kondo, M; Nagai, A; Nakata, J; Nishimura, K; Tamaoki, J, 2000)
"Little is known about the anti-asthmatic effects of powerful anti-inflammatory agents such as aspirin-like drugs."5.09Different effects of inhaled aspirinlike drugs on allergen-induced early and late asthmatic responses. ( Bianco, S; Pieroni, MG; Refini, RM; Robuschi, M; Sestini, P; Vaghi, A, 1999)
"day-1 for 4 days), on cough response to inhaled capsaicin were examined in eight patients with asthma, 10 patients with chronic bronchitis, and 10 normal subjects."5.08Prostanoids and cough response to capsaicin in asthma and chronic bronchitis. ( Bando, T; Fujimura, M; Hashimoto, T; Kamio, Y; Kasahara, K; Matsuda, T, 1995)
" In study 1, 15 non-aspirin sensitive patients with mild asthma attended on four occasions and inhaled 5 ml of lysine aspirin (L-aspirin) 900 mg, indomethacin 50 mg, sodium salicylate 800 mg, or saline 20 minutes before an inhaled MBS challenge."5.08Comparison of three inhaled non-steroidal anti-inflammatory drugs on the airway response to sodium metabisulphite and adenosine 5'-monophosphate challenge in asthma. ( Knox, A; Pavord, I; Tattersfield, A; Wang, M; Wisniewski, A, 1996)
"We evaluated the effect of inhaled indomethacin, a nonsteroidal antiinflammatory drug (NSAID), against bronchoconstriction induced by ultrasonically nebulized distilled water (UNDW) in children with asthma."5.08Inhaled indomethacin prevents bronchoconstrictive response to distilled water but not to histamine in children with asthma. ( Kuroume, T; Maeda, S; Mochizuki, H; Morikawa, A; Shigeta, M; Shimizu, T, 1995)
"These results suggest an important role of cyclooxygenase pathway products in decreased response to repeated inhalation of acetaldehyde in patients with asthma."5.08Inhibitory effect of indomethacin on tachyphylaxis in response to acetaldehyde-induced bronchoconstriction in patients with asthma. ( Fujimura, M; Kamio, Y; Matsuda, T; Myou, S, 1997)
" To investigate whether prostaglandin production could also modulate the bronchial antireactive activity of this diuretic drug, we investigated the effect of inhaled lysine acetylsalicylate (162 mg) and of furosemide (18 mg), alone and in combination, on the bronchial obstructive response to ultrasonically nebulized water in asthmatic patients."5.07Potentiation of the antireactive, antiasthmatic effect of inhaled furosemide by inhaled lysine acetylsalicylate. ( Berni, F; Bianco, S; Pieroni, MG; Refini, RM; Robuschi, M; Sestini, P; Vaghi, A, 1993)
"The effect of indomethacin on the capacity of LTE4 to enhance airway histamine responsiveness was evaluated in eight mild asthmatic subjects."5.07Effect of indomethacin on leukotriene4-induced histamine hyperresponsiveness in asthmatic subjects. ( Christie, PE; Hawksworth, R; Lee, TH; Spur, BW, 1992)
"The present investigation was designed to evaluate the effects of pre-treatment with the cholinergic muscarinic receptor antagonist, atropine sulfate, or with the cyclooxygenase inhibitor, indomethacin, on adenosine-induced bronchoconstriction in human asthmatics."5.06Adenosine-induced bronchoconstriction in human asthmatics: effects of pretreatment with indomethacin or atropine sulfate. ( Diamond, L; Küng, M, 1990)
"We have examined the effects of indomethacin (I) on tolerance to the bronchomotor effects of repetitive challenge with exercise (EX) and eucapnic hyperpnea (EH) in 7 asthmatic subjects."5.06Indomethacin blocks airway tolerance to repetitive exercise but not to eucapnic hyperpnea in asthmatic subjects. ( Bigby, BG; Boushey, HA; Margolskee, DJ, 1988)
"The effect of specific antigen challenge on the lung function of eight allergic asthmatic patients after placebo and indomethacin pretreatment has been investigated."5.05Lung function and plasma levels of thromboxane B2, 6-ketoprostaglandin F1 alpha and beta-thromboglobulin in antigen-induced asthma before and after indomethacin pretreatment. ( Joubert, JR; Macfarlane, CM; Malan, L; Mouton, W; Shephard, EG, 1985)
"Inhalation histamine challenges were performed in groups of normal and asthmatic subjects."5.05Prostaglandins and the control of airways responses to histamine in normal and asthmatic subjects. ( Walters, EH, 1983)
" Indomethacin had no effect on day-to-day asthmatic symptoms, or challenge-induced asthma, suggesting that prostaglandins are not fundamental to the pathogenesis of asthma."5.04The response of normal and asthmatic subjects to prostaglandins E2 and F2alpha by different routes, and their significance in asthma. ( Cuthbert, MF; Smith, AP, 1976)
" To determine the beneficial effects of statins on the airway hyperresponsiveness, a characteristic feature of allergic bronchial asthma, the effect of systemic treatment with lovastatin on antigen-induced bronchial smooth muscle hyperresponsiveness was investigated in mice."3.74Inhibition of antigen-induced bronchial smooth muscle hyperresponsiveness by lovastatin in mice. ( Chiba, Y; Misawa, M; Sato, S, 2008)
"Starting with the weak agonist indomethacin, a series of potent, selective CRTh2 (DP(2)) antagonists have been discovered as potential treatments for asthma, allergic rhinitis and other inflammatory diseases."3.73Discovery of potent CRTh2 (DP2) receptor antagonists. ( Arrowsmith, EC; Beech, C; Bell, FM; Birkinshaw, TN; Bonnert, RV; Carrillo, JJ; Dougall, IG; Hill, S; Paine, SW; Patel, A; Phillips, TT; Reakes, S; Salter, S; Sanganee, H; Schmidt, J; Teague, SJ; Weaver, R, 2006)
" The cells were isolated from 3 groups of subjects: nonasthmatic patients (n = 10), patients with aspirin-tolerant asthma (ATA, n = 9), and patients with aspirin-intolerant asthma (AIA, n = 7)."3.72Deficient prostaglandin E2 production by bronchial fibroblasts of asthmatic patients, with special reference to aspirin-induced asthma. ( Pierzchalska, M; Sanak, M; Soja, J; Szabó, Z; Szczeklik, A, 2003)
"A life-threatening episode of bronchial asthma may follow treatment by ophthalmic indomethacin."3.69Acute bronchial asthma associated with the administration of ophthalmic indomethacin. ( Polachek, J; Shvartzman, P, 1996)
"The anti-asthmatic effects of CS-518 (sodium 2-(1-imidazolylmethyl)-4,5-dihydrobenzo[b]thiophene-6-carboxylate) , a specific thromboxane A2 (TXA2) synthase inhibitor, were investigated in the ovalbumin-sensitized guinea pig asthmatic model."3.68Effects of CS-518, a thromboxane synthase inhibitor, on the asthmatic response. ( Iizuka, Y; Itoh, K; Mukaiyama, O; Satoh, Y; Terada, A; Yamaguchi, T, 1993)
"To determine whether the involvement of thromboxane A2 in bronchial hyperresponsiveness (BHR) is specific to asthma, we examined the effects of a selective inhibitor of thromboxane synthetase (OKY-046) and a cyclooxygenase inhibitor (indomethacin) on bronchial responsiveness to methacholine in normal subjects and patients with chronic bronchitis, diffuse bronchiectasis, and intrinsic bronchial asthma."3.68Attenuating effect of a thromboxane synthetase inhibitor (OKY-046) on bronchial responsiveness to methacholine is specific to bronchial asthma. ( Fujimura, M; Matsuda, T; Sakamoto, S, 1990)
"Histamine release induced by platelet-activating factor (PAF) from leukocytes of aspirin-sensitive subjects with asthma was higher than that from normal control subjects, despite the similarity of anti-IgE-induced histamine release."3.68Basophil histamine release by platelet-activating factor in aspirin-sensitive subjects with asthma. ( Hattori, H; Kishimoto, S; Miyatake, A; Okuda, Y; Takashima, T; Tsuyuguchi, I; Yamatodani, A, 1990)
"Airway reactivity to histamine was determined in a group of non-asthmatic and asthmatic patients prior to thoracotomy."3.67Human isolated bronchial muscle preparations from asthmatic patients: effects of indomethacin and contractile agonists. ( Benveniste, J; Brink, C; Cerrina, J; Haye-Legrande, I; Labat, C; Raffestin, B, 1989)
"The formation of 5-lipoxygenase products of arachidonic acid, 5-HETE and 5,12-diHETE, was determined in 100,000 X g supernatant of polymorphonuclear leukocytes from 17 healthy subjects, 17 patients with extrinsic asthma and 15 patients with intrinsic asthma."3.67Increased activity of 5-lipoxygenase in polymorphonuclear leukocytes from asthmatic patients. ( Mita, H; Shida, T; Taniguchi, N; Yasueda, H; Yui, Y, 1985)
"Twenty-nine patients with asthma and aspirin-sensitivity were studied in an attempt to induce tolerance to aspirin (ASA)."3.67Aspirin tolerance induced in aspirin-sensitive asthmatics. ( Grzelewska-Rzymowska, I; Kowalski, ML; Rozniecki, J; Szmidt, M, 1984)
"The bronchoconstriction induced by repeated histamine inhalation tests was studied in eight mild stable asthmatic subjects to determine whether histamine tachyphylaxis occurs in asthmatics."3.67Tachyphylaxis to inhaled histamine in asthmatic subjects. ( Jones, GL; Manning, PJ; O'Byrne, PM, 1987)
"Aspirin-sensitive asthma is a common and severe disorder characterized by asthmatic attacks after oral ingestion of cyclooxygenase inhibiting drugs."3.67[Demonstration of specific platelet function anomaly in asthma induced by aspirin: diagnostic consequences]. ( Ameisen, JC; Capron, A; Fournier, E; Joseph, M; Pancré, V; Tonnel, AB; Vorng, H; Wallaert, B, 1985)
" The pharmacologic characteristics of the antigen-induced airway smooth muscle contraction in vitro were similar to those induced by arachidonic acid and the leukotrienes only in some respects but were clearly different from those induced by compound 48/80."3.67Pharmacological characterization of airway smooth muscle responses to antigen in ascaris-sensitive dogs. ( Davis, C; Kannan, L; Kannan, MS; Ladenius, AR; Sankaranarayanan, A, 1986)
"In an attempt to elucidate the mechanisms involved in analgesic-induced asthma, I performed bronchial and intravenous challenge tests with indomethacin in 5 aspirin-sensitive asthmatics."3.66Bronchial and intravenous provocation tests with indomethacin in aspirin-sensitive asthmatics. ( Martelli, NA, 1979)
" A), and the effects of histamine and indomethacin upon these responses, in normal subjects, and patients with extrinsic and intrinsic asthma, and chronic bronchitis."3.66Intrinsic and extrinsic asthma, a shared lymphocyte abnormality. ( Brostoff, J; Hudspith, BN; Johnson, NM; Swinburn, CR, 1983)
"We studied the effect of ascorbic acid in 14 mild asthmatic subjects."3.66Effect of ascorbic acid on response to methacholine challenge in asthmatic subjects. ( Douglas, JS; Dubois, AB; Mohsenin, V, 1983)
"Thirty aspirin-sensitive asthmatic patients underwent incremental, oral aspirin challenge until a "positive reaction" (delta FEV1 greater than or equal to 25%) occurred."3.66Aspirin desensitization in aspirin-sensitive asthmatic patients: clinical manifestations and characterization of the refractory period. ( Mathison, DA; Pleskow, WW; Schatz, M; Simon, RA; Stevenson, DD; Zeiger, RS, 1982)
" 9 The results are also discussed in relation to the genesis of aspirin-induced asthma in man."3.66Spontaneous activity in the trachea of dogs treated with indomethacin: an experimental model for aspirin-related asthma. ( Ito, Y; Tajima, K, 1981)
"To examine the role of arachidonic acid metabolism in the modulation of immediate-type immunologic airway responses, we compared the effects of indomethacin (50 mg every 6 h for 96 h) and placebo on responses to antigen inhalation challenge in allergic asthmatic subjects and a group of nonasthmatic subjects with allergic rhinitis."3.66Indomethacin modification of immediate-type immunologic airway responses in allergic asthmatic and non-asthmatic subjects: evidence for altered arachidonic acid metabolism in asthma. ( Adkinson, NF; Ankin, MG; Fish, JE; Peterman, VI, 1981)
" An analogous mechanism may account for aspirin-induced asthma in man."3.66Evidence for lipoxygenase pathway involvement in allergic tracheal contraction. ( Burka, JF; Paterson, NA, 1980)
"The effect of indomethacin is reported in five patients with chronic asthma."3.65Treatment of chronic airways obstruction with indomethacin. ( Eddey, V; Hume, M, 1977)
"Challenge tests with some analgesics in common use were performed in five aspirin-sensitive asthmatics."3.65Response of aspirin-allergic patients to challenge by some analgesics in common use. ( Smith, AP, 1971)
"Eleven patients with asthma and aspirin hypersensitivity have been challenged with eight non-steroidal anti-inflammatory drugs."3.65Relationship of inhibition of prostaglandin biosynthesis by analgesics to asthma attacks in aspirin-sensitive patients. ( Czerniawska-Mysik, G; Gryglewski, RJ; Szczeklik, A, 1975)
" UNDW responsiveness was assessed with dose-response curves of UNDW volume output versus the percent fall in FEV1."2.66The effect of indomethacin on the refractory period occurring after the inhalation of ultrasonically nebulized distilled water. ( Ciappi, G; Corbo, GM; Foresi, A; Mattoli, S; Valente, S, 1987)
"Bradykinin (BK) is an endogenous mediator that activates C fibers."1.33Prostaglandin involvement in lung C-fiber activation by substance P in guinea pigs. ( Bergren, DR, 2006)
"Indomethacin has been used to demonstrate that cyclooxygenase (COX) metabolites of arachidonic acid play a mechanistic role in ozone-induced spirometric decline in normals (Nm)."1.31Cyclooxygenase metabolites play a different role in ozone-induced pulmonary function decline in asthmatics compared to normals. ( Alexis, N; Corey, P; O'Byrne, P; Pengelly, D; Silverman, F; Tarlo, S; Urch, B, 2000)
"Indomethacin tended to enhance antigen-induced contractions of the trachea and significantly enhanced contractions of the lung parenchyma."1.29Effect of anti-inflammatory agent etodolac on antigen-induced contractions of the trachea and lung parenchyma of guinea pigs. ( Hamada, K; Inoue, K; Kimura, K; Shibata, Y; Ueda, F, 1994)
"A 23-year-old male with bronchial asthma developed eosinophilia (eosinophils greater than 2,000/mm3) and was observed at our hospital."1.28[Acute myocardial injury and repeated angina pectoris-like attacks in a young patient with Churg-Strauss syndrome]. ( Arai, Y; Fukushima, N; Isokane, N; Miyamoto, Y; Sano, Y; Suzuki, N, 1991)
" Dose-response lines in response to the two agonists, expressed as percent maximal contraction, did not differ among the groups."1.28Muscarinic-receptor functioning in tracheas from normal and ovalbumin-sensitive guinea pigs. ( Biggs, DF; Yang, ZJ, 1991)
"Pretreatment with indomethacin, 30 mg/kg given intraperitoneally, significantly potentiates the decrements in Cdyn and GL elicited by aerosol LTC4 at 1 microgram/ml."1.27Indomethacin potentiates the pulmonary response to aerosol leukotriene C4 in the guinea pig. ( Austen, KF; Corey, EJ; Drazen, JM; Leitch, AG, 1983)
"Indomethacin pretreatment totally or partially inhibited the delayed asthmatic response in 10 of 11 subjects."1.27Non-steroid anti-inflammatory drugs in asthma: dangerous or useful therapy? ( Joubert, JR; Mouton, W; Shephard, E; Van Zyl, L; Viljoen, I, 1985)
" We determined the nebulizer concentration of PAF which reduced specific airway conductance (SGaw) 35% (PC35 SGaw) and the slope of the PAF dose-response curve."1.27Mechanism of platelet activating factor-induced bronchoconstriction in humans. ( Patterson, R; Rubin, AH; Smith, LJ, 1988)
" Salicylamide, an analgesic without effect on the prostaglandin synthesis was in the oral exposition test of 18 patients with proved analgesics-asthma-syndrome in the dosage of 500 mg subjectively and objectively tolerated without reaction."1.26[Salicylamide-- a potential pain-remedy alternative in the analgesic asthma syndrome]. ( Hummel, S; Jäger, L; Slapke, J, 1979)
"Prevention of arterial hypoxemia by oxygen breathing blocked an increase in pulmonary vascular resistance in four pretreated responders."1.26Failure of hypoxic pulmonary vasoconstriction in the canine asthma model. Effect of prostaglandin inhibitors. ( Baier, H; Cohn, MA; Wanner, A, 1978)
"Eight patients with type I allergic bronchial asthma were given specific allergens by inhalation until symptoms and signs of asthma attacks were provoked."1.26Aspects of prostaglandin action in asthma. ( Gréen, K; Hedqvist, P; Svanborg, N, 1976)

Research

Studies (142)

TimeframeStudies, this research(%)All Research%
pre-199087 (61.27)18.7374
1990's37 (26.06)18.2507
2000's13 (9.15)29.6817
2010's4 (2.82)24.3611
2020's1 (0.70)2.80

Authors

AuthorsStudies
Pettipher, R1
Whittaker, M1
Zasłona, Z1
Flis, E1
Wilk, MM1
Carroll, RG1
Palsson-McDermott, EM1
Hughes, MM1
Diskin, C1
Banahan, K1
Ryan, DG1
Hooftman, A1
Misiak, A1
Kearney, J1
Lochnit, G1
Bertrams, W1
Greulich, T1
Schmeck, B1
McElvaney, OJ1
Mills, KHG1
Lavelle, EC1
Wygrecka, M1
Creagh, EM1
O'Neill, LAJ1
Riley, JP1
Fuchs, B1
Sjöberg, L1
Nilsson, GP1
Karlsson, L1
Dahlén, SE1
Rao, NL1
Adner, M1
Zhou, W1
Zhang, J1
Goleniewska, K1
Dulek, DE1
Toki, S1
Newcomb, DC1
Cephus, JY1
Collins, RD1
Wu, P1
Boothby, MR1
Peebles, RS1
Chiba, Y1
Sato, S1
Misawa, M1
Rievaj, J1
Davidson, C1
Nadeem, A1
Hollenberg, M1
Duszyk, M1
Vliagoftis, H1
Prasad, K1
Gupta, JB1
Gray, PA1
Warner, TD1
Vojnovic, I1
Del Soldato, P1
Parikh, A1
Scadding, GK1
Mitchell, JA1
Kajekar, R1
Undem, BJ1
Myers, AC1
Pierzchalska, M1
Szabó, Z1
Sanak, M1
Soja, J1
Szczeklik, A3
Fernandez, J1
Reyes, R1
Ponce, H1
Oropeza, M1
Vancalsteren, MR1
Jankowski, C1
Campos, MG1
Bergren, DR1
Birkinshaw, TN1
Teague, SJ1
Beech, C1
Bonnert, RV1
Hill, S1
Patel, A1
Reakes, S1
Sanganee, H1
Dougall, IG1
Phillips, TT1
Salter, S1
Schmidt, J1
Arrowsmith, EC1
Carrillo, JJ1
Bell, FM1
Paine, SW1
Weaver, R1
Vanselow, NA1
Smith, JR1
Piper, PJ1
Hindmarsh, KW1
LeGatt, DF1
Cade, JF1
Clancy, RL1
Walker, SE1
Pain, MC1
Walters, EH2
Resta, O1
Foschino-Barbaro, MP1
Carnimeo, N1
Bavoso, P1
Picca, V1
Morley, J2
Fairfax, AJ2
Hanson, JM2
Leitch, AG1
Corey, EJ1
Austen, KF1
Drazen, JM1
Swinburn, CR1
Hudspith, BN1
Brostoff, J1
Johnson, NM2
Kowalski, ML3
Grzelewska-Rzymowska, I3
Rozniecki, J4
Szmidt, M3
Burka, JF1
Paterson, NA1
Patterson, R2
Harris, KE1
Seale, JP2
Mohsenin, V1
Dubois, AB1
Douglas, JS1
Pleskow, WW1
Stevenson, DD1
Mathison, DA1
Simon, RA1
Schatz, M1
Zeiger, RS1
Ito, Y1
Tajima, K1
Fish, JE1
Ankin, MG1
Adkinson, NF2
Peterman, VI1
Souza, LM1
Silverman, M1
Nakajima, N1
Ichinose, M1
Takahashi, T1
Yamauchi, H1
Igarashi, A1
Miura, M1
Inoue, H1
Takishima, T2
Shirato, K1
Shimizu, T1
Mochizuki, H1
Maeda, S1
Shigeta, M1
Morikawa, A1
Kuroume, T1
Aibara, S1
Mori, M1
Tsukada, W1
Inoue, K1
Hamada, K1
Ueda, F1
Shibata, Y1
Kimura, K1
Bianco, S3
Vaghi, A2
Pieroni, MG2
Robuschi, M2
Refini, RM2
Berni, F1
Sestini, P2
Pavord, ID1
Wisniewski, A2
Tattersfield, AE1
Howell, RE1
Woeppel, SL1
Yamaguchi, T1
Mukaiyama, O1
Itoh, K1
Satoh, Y1
Terada, A1
Iizuka, Y1
Fujimura, M5
Kamio, Y2
Kasahara, K1
Bando, T1
Hashimoto, T1
Matsuda, T5
Field, PI1
Simmul, R1
Bell, SC1
Allen, DH1
Berend, N1
Morimoto, R1
Koyama, S1
Tanaka, A1
Horie, T1
Wang, M1
Pavord, I1
Knox, A1
Tattersfield, A1
Polachek, J1
Shvartzman, P1
Rodwell, LT1
Anderson, SD1
Spring, J1
Mohamed, S1
Myou, S1
Tamaoki, J2
Nakata, J1
Nishimura, K1
Kondo, M1
Aoshiba, K1
Kawatani, K1
Nagai, A1
Arakida, Y1
Ohga, K1
Okada, Y1
Morio, H1
Suwa, K1
Yokota, M1
Yamada, T1
Freed, AN1
McCulloch, S1
Wang, Y1
Alexis, N1
Urch, B1
Tarlo, S1
Corey, P1
Pengelly, D1
O'Byrne, P1
Silverman, F1
Tohda, Y1
Muraki, M1
Kubo, H1
Itoh, M1
Haraguchi, R1
Nakajima, S1
Fukuoka, M1
Chand, N1
Deroth, L1
Eyre, P1
Smith, AP4
Dunlop, L1
Bouhuys, A1
Martelli, NA1
Slapke, J1
Hummel, S1
Jäger, L1
Pasargiklian, M1
Allegra, L1
Kordansky, D1
Norman, PS1
Rosenthal, RR1
Kitamura, S2
Ishihara, Y2
Sugiyama, Y1
Black, AE1
Clarke, SW1
Hume, M1
Eddey, V1
Irokawa, M2
Nemoto, T1
Nakazawa, T3
Fueki, R1
Kobayashi, S3
Cohn, MA1
Baier, H1
Wanner, A2
Uchiyama, K1
Yoshikawa, T1
Munakata, M1
Yoshida, H1
Asanuma, Y1
Yomaida, I1
Takahashi, W1
Ohsaki, Y1
Murao, M1
Hirata, F1
Gryglewski, RJ2
Nizankowska, E1
Cuthbert, MF2
Toyoda, T1
Furukawa, M1
Taya, T1
Michoud, MC1
Fraser, RS1
Pare, PD1
Hogg, JC1
Santiago, SM1
Klaustermeyer, WB1
Svanborg, N1
Hedqvist, P1
Gréen, K1
Czerniawska-Mysik, G1
Droszcz, W1
Christie, PE1
Hawksworth, R1
Spur, BW1
Lee, TH1
Saito, M1
Sakamoto, S2
Miyake, Y1
Shintani, H1
Yasui, M1
Okuda, Y1
Hattori, H1
Takashima, T1
Miyatake, A1
Yamatodani, A1
Tsuyuguchi, I1
Kishimoto, S1
Knight, DA1
Phillips, MJ1
Stewart, GA1
Thompson, PJ1
Suzuki, N1
Arai, Y1
Miyamoto, Y1
Isokane, N1
Fukushima, N1
Sano, Y1
Uchida, M1
Imanishi, N1
Sugasawa, T1
Morooka, S1
Nakagawa, T1
Mizushima, Y1
Ishii, A1
Nambu, F1
Motoishi, M1
Yui, Y2
Shida, T2
Miyamoto, T1
Sladek, K2
Sheller, JR2
FitzGerald, GA2
Morrow, JD1
Roberts, LJ1
Orlov, SM1
Vlasov, AA1
Savel'eva, VF1
Lipatkina, LIu1
Kulikov, VI1
Yang, ZJ1
Biggs, DF1
Williams, WR1
Pawlowicz, A1
Davies, BH1
Fernandes, LB1
Preuss, JM1
Paterson, JW1
Goldie, RG1
Yamaya, M1
Zayasu, K1
Sekizawa, K2
Yamauchi, K1
Fukushima, T1
Sasaki, H1
Makino, S1
Gulbenkian, AR1
Fernandez, X1
Kreutner, W1
Minnicozzi, M1
Watnick, AS1
Kung, T1
Egan, RW1
Küng, M1
Diamond, L1
Dworski, R1
Buitkus, KL1
Block, FJ1
Marney, SR1
Stevens, WH1
Manning, PJ2
Watson, RM1
O'Byrne, PM4
Doucet, MY1
Jones, TR1
Ford-Hutchinson, AW1
Pearson, DJ1
Suarez-Mendez, VJ1
Holgate, ST1
Hardy, C1
Robinson, C1
Agius, RM1
Howarth, PH1
Nagai, H1
Yakuo, I1
Togawa, M1
Arimura, A1
Matsuura, N1
Koda, A1
Hamano, S1
Ujiie, A1
Nakazawa, M1
Kirby, JG1
Hargreave, FE1
Cockcroft, DW1
Viganò, T1
Crivellari, MT1
Sala, A1
Ortolani, C2
Galli, G1
Folco, GC1
Peters, SP1
Tung, RS1
Chatham, M1
Bleecker, ER1
Lichtenstein, LM1
Shephard, EG1
Malan, L1
Macfarlane, CM1
Mouton, W2
Joubert, JR2
Abraham, WM2
Stevenson, JS1
Garrido, R1
Sheehan, GJ1
Kutzner, MR1
Chin, WD1
Cerrina, J1
Labat, C1
Haye-Legrande, I1
Raffestin, B1
Benveniste, J1
Brink, C1
Webber, SE1
Salonen, RO1
Deffebach, ME1
Widdicombe, JG1
Daffonchio, L1
Abbracchio, MP1
Cattabeni, F1
Berti, F1
Omini, C1
Pastorello, E1
Qualizza, RM1
Luraghi, MT1
Ispano, M1
Villa, AM1
Zanussi, C1
Mita, H1
Taniguchi, N1
Yasueda, H1
Herjavecz, I1
Huszár, E1
Böszörményi-Nagy, G1
Debreczeni, L1
Kannan, MS1
Davis, C1
Sankaranarayanan, A1
Ladenius, AR1
Kannan, L1
Sasaki, F1
Mifune, J1
Boris, M1
Schiff, M1
Weindorf, S1
Smith, LJ1
Rubin, AH1
Margolskee, DJ1
Bigby, BG1
Boushey, HA1
Fujiwara, T1
Itoh, T1
Kuriyama, H1
Sielczak, M1
Mella, JF1
Mattoli, S1
Foresi, A1
Corbo, GM1
Valente, S1
Ciappi, G1
Ueki, IF1
Graf, PD1
Nadel, JA1
Bigby, TD1
Hay, DW1
Farmer, SG1
Raeburn, D1
Muccitelli, RM1
Wilson, KA1
Fedan, JS1
Jones, GL2
Molotkov, VN1
Chernushenko, RF1
Kogosova, LS1
Petrashenko, AI1
Morozova, NA1
Ameisen, JC1
Joseph, M1
Tonnel, AB1
Vorng, H1
Pancré, V1
Fournier, E1
Wallaert, B1
Capron, A1
Shephard, E1
Van Zyl, L1
Viljoen, I1
Fink, A1
Bibi, H1
Eliraz, A1
Tabachnik, E1
Bentwich, Z1
Umegae, Y1
Matsui, S1
Cervini, C1
Reed, CE1
Koger, EL1
Klaassen, CH1
Fisherman, EW1
Cohen, GN1
Samter, M1
Beers, RF1
Fusco, FA1
Azzolini, A1
Dolcino, G1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Challenge Test for Acetylsalicylic Acid Hypersensitivity[NCT01681615]50 participants (Anticipated)Interventional2012-09-30Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for indomethacin and Asthma, Bronchial

ArticleYear
Update on the development of antagonists of chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2). From lead optimization to clinical proof-of-concept in asthma and allergic rhinitis.
    Journal of medicinal chemistry, 2012, Apr-12, Volume: 55, Issue:7

    Topics: Acetates; Animals; Asthma; Aza Compounds; Carbazoles; Clinical Trials as Topic; Humans; Indoleacetic

2012
Prostaglandins, slow-reacting substances (leukotrienes) and the lung.
    Australian and New Zealand journal of medicine, 1981, Volume: 11, Issue:5

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Asthma; Bronchi; Epoprostenol; Guinea Pigs; H

1981
The mast cell as a primary effector cell in the pathogenesis of asthma.
    The Journal of allergy and clinical immunology, 1986, Volume: 77, Issue:2

    Topics: Aspirin; Asthma; Bronchi; Bronchial Provocation Tests; Eosinophils; Histamine Release; Humans; Immun

1986
[Hypersensitivity to aspirin and other non-steroidal anti- inflammatory agents--the methods of detecting the hypersensitivity and the development of the state of tolerance].
    Polskie Archiwum Medycyny Wewnetrznej, 1989, Volume: 81, Issue:2

    Topics: Aspirin; Asthma; Bronchial Provocation Tests; Drug Hypersensitivity; Drug Tolerance; Humans; Indomet

1989
The pathogenesis of asthma.
    The Medical clinics of North America, 1974, Volume: 58, Issue:1

    Topics: Acetaminophen; Adult; Affective Symptoms; Air Pollution; Aspirin; Asthma; Autonomic Nervous System;

1974

Trials

27 trials available for indomethacin and Asthma, Bronchial

ArticleYear
Asthma relieved by acetylsalicylic acid and nonsteroid anti-inflammatory drugs.
    Respiration; international review of thoracic diseases, 1984, Volume: 46, Issue:1

    Topics: Anti-Inflammatory Agents; Aspirin; Asthma; Dipyrone; Female; Forced Expiratory Volume; Humans; Indom

1984
Prostaglandins and the control of airways responses to histamine in normal and asthmatic subjects.
    Thorax, 1983, Volume: 38, Issue:3

    Topics: Adult; Airway Resistance; Albuterol; Asthma; Bronchial Provocation Tests; Dose-Response Relationship

1983
Inhaled indomethacin prevents bronchoconstrictive response to distilled water but not to histamine in children with asthma.
    American journal of respiratory and critical care medicine, 1995, Volume: 152, Issue:2

    Topics: Administration, Inhalation; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Child; Cross-O

1995
Potentiation of the antireactive, antiasthmatic effect of inhaled furosemide by inhaled lysine acetylsalicylate.
    Allergy, 1993, Volume: 48, Issue:8

    Topics: Administration, Inhalation; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Ast

1993
Refractoriness to inhaled sodium metabisulphite in subjects with mild asthma.
    The European respiratory journal, 1994, Volume: 7, Issue:1

    Topics: Administration, Inhalation; Adult; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Double-

1994
Prostanoids and cough response to capsaicin in asthma and chronic bronchitis.
    The European respiratory journal, 1995, Volume: 8, Issue:9

    Topics: Adult; Aged; Asthma; Bronchial Provocation Tests; Bronchitis; Capsaicin; Chronic Disease; Cough; Cro

1995
Evidence for opioid modulation and generation of prostaglandins in sulphur dioxide (SO)2-induced bronchoconstriction.
    Thorax, 1996, Volume: 51, Issue:2

    Topics: Adult; Asthma; Bronchoconstriction; Bronchoconstrictor Agents; Cyclooxygenase Inhibitors; Dose-Respo

1996
Comparison of three inhaled non-steroidal anti-inflammatory drugs on the airway response to sodium metabisulphite and adenosine 5'-monophosphate challenge in asthma.
    Thorax, 1996, Volume: 51, Issue:8

    Topics: Adenosine Monophosphate; Administration, Inhalation; Adult; Anti-Inflammatory Agents, Non-Steroidal;

1996
Effect of inhaled frusemide and oral indomethacin on the airway response to hypertonic saline challenge in asthmatic subjects.
    Thorax, 1997, Volume: 52, Issue:1

    Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Bronchial Provocation Tests; Dos

1997
Inhibitory effect of indomethacin on tachyphylaxis in response to acetaldehyde-induced bronchoconstriction in patients with asthma.
    The Journal of allergy and clinical immunology, 1997, Volume: 99, Issue:5

    Topics: Acetaldehyde; Administration, Inhalation; Administration, Oral; Adult; Aged; Asthma; Bronchoconstric

1997
Different effects of inhaled aspirinlike drugs on allergen-induced early and late asthmatic responses.
    American journal of respiratory and critical care medicine, 1999, Volume: 159, Issue:4 Pt 1

    Topics: Administration, Inhalation; Adolescent; Adult; Allergens; Anti-Inflammatory Agents, Non-Steroidal; A

1999
Effect of inhaled indomethacin in asthmatic patients taking high doses of inhaled corticosteroids.
    The Journal of allergy and clinical immunology, 2000, Volume: 105, Issue:6 Pt 1

    Topics: Administration, Inhalation; Adrenal Cortex Hormones; Adult; Asthma; Beclomethasone; Double-Blind Met

2000
Clinical, functional and pathogenetic aspects of bronchial reactivity to prostaglandins F2alpha, E1, and E2.
    Advances in prostaglandin and thromboxane research, 1976, Volume: 1

    Topics: Adult; Aerosols; Airway Resistance; Allergens; Asthma; Bronchial Spasm; Bronchitis; Clinical Trials

1976
Asthma improved by nonsteroidal anti-inflammatory drugs.
    Annals of internal medicine, 1978, Volume: 88, Issue:4

    Topics: Airway Resistance; Anti-Inflammatory Agents; Aspirin; Asthma; Clinical Trials as Topic; Female; Forc

1978
Effect of indomethacin in asthma: evidence against a role for prostaglandins in its pathogenesis.
    British journal of clinical pharmacology, 1975, Volume: 2, Issue:4

    Topics: Adolescent; Adult; Antigens; Asthma; Capsules; Clinical Trials as Topic; Female; Forced Expiratory V

1975
The response of normal and asthmatic subjects to prostaglandins E2 and F2alpha by different routes, and their significance in asthma.
    Advances in prostaglandin and thromboxane research, 1976, Volume: 1

    Topics: Adolescent; Adult; Aerosols; Allergens; Asthma; Bronchi; Clinical Trials as Topic; Dose-Response Rel

1976
Effect of indomethacin on leukotriene4-induced histamine hyperresponsiveness in asthmatic subjects.
    The American review of respiratory disease, 1992, Volume: 146, Issue:6

    Topics: Adult; Airway Resistance; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Female; Hi

1992
Effect of leukotriene antagonist on experimental and clinical bronchial asthma.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1991, Volume: 21A

    Topics: Allergens; Anaphylaxis; Animals; Asthma; Bronchi; Bronchial Provocation Tests; Chromones; Drug Evalu

1991
Adenosine-induced bronchoconstriction in human asthmatics: effects of pretreatment with indomethacin or atropine sulfate.
    Pulmonary pharmacology, 1990, Volume: 3, Issue:1

    Topics: Adenosine; Administration, Inhalation; Administration, Oral; Adult; Asthma; Atropine; Bronchial Prov

1990
Allergen-stimulated release of thromboxane A2 and leukotriene E4 in humans. Effect of indomethacin.
    The American review of respiratory disease, 1990, Volume: 141, Issue:6

    Topics: Adult; Allergens; Arachidonate 5-Lipoxygenase; Asthma; Bronchial Provocation Tests; Humans; Indometh

1990
Tachyphylaxis to inhaled methacholine in normal but not asthmatic subjects.
    Journal of applied physiology (Bethesda, Md. : 1985), 1990, Volume: 69, Issue:3

    Topics: Administration, Inhalation; Adult; Asthma; Bronchodilator Agents; Female; Flurbiprofen; Forced Expir

1990
Effect of indomethacin on allergen-induced asthmatic responses.
    Journal of applied physiology (Bethesda, Md. : 1985), 1989, Volume: 66, Issue:2

    Topics: Adult; Allergens; Asthma; Clinical Trials as Topic; Cyclooxygenase Inhibitors; Double-Blind Method;

1989
Lung function and plasma levels of thromboxane B2, 6-ketoprostaglandin F1 alpha and beta-thromboglobulin in antigen-induced asthma before and after indomethacin pretreatment.
    British journal of clinical pharmacology, 1985, Volume: 19, Issue:4

    Topics: 6-Ketoprostaglandin F1 alpha; Adolescent; Adult; Asthma; Beta-Globulins; beta-Thromboglobulin; Human

1985
Injection of low-dose antigen attenuates the response to subsequent bronchoprovocative challenge.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 1988, Volume: 98, Issue:6

    Topics: Adult; Antigens; Asthma; Bronchial Provocation Tests; Child; Clinical Trials as Topic; Female; Human

1988
Indomethacin blocks airway tolerance to repetitive exercise but not to eucapnic hyperpnea in asthmatic subjects.
    The American review of respiratory disease, 1988, Volume: 137, Issue:4

    Topics: Adaptation, Physiological; Adult; Airway Resistance; Asthma; Bronchi; Female; Humans; Hyperventilati

1988
The effect of indomethacin on the refractory period occurring after the inhalation of ultrasonically nebulized distilled water.
    The Journal of allergy and clinical immunology, 1987, Volume: 79, Issue:4

    Topics: Adolescent; Adult; Asthma; Bronchial Diseases; Clinical Trials as Topic; Constriction, Pathologic; E

1987
The effect of indomethacin on exercise-induced bronchoconstriction and refractoriness after exercise.
    The American review of respiratory disease, 1986, Volume: 134, Issue:1

    Topics: Adult; Asthma; Asthma, Exercise-Induced; Female; Forced Expiratory Volume; Humans; Indomethacin; Mal

1986

Other Studies

110 other studies available for indomethacin and Asthma, Bronchial

ArticleYear
Caspase-11 promotes allergic airway inflammation.
    Nature communications, 2020, 02-26, Volume: 11, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Caspases, Initiator; Cells, Cultured; Dino

2020
Mast cell mediators cause early allergic bronchoconstriction in guinea-pigs in vivo: a model of relevance to asthma.
    Clinical science (London, England : 1979), 2013, Volume: 125, Issue:11

    Topics: Acetates; Animals; Asthma; Bronchial Hyperreactivity; Constriction, Pathologic; Cyclopropanes; Disea

2013
Prostaglandin I2 Suppresses Proinflammatory Chemokine Expression, CD4 T Cell Activation, and STAT6-Independent Allergic Lung Inflammation.
    Journal of immunology (Baltimore, Md. : 1950), 2016, 09-01, Volume: 197, Issue:5

    Topics: Allergens; Animals; Antihypertensive Agents; Asthma; CD4-Positive T-Lymphocytes; Cell Proliferation;

2016
Inhibition of antigen-induced bronchial smooth muscle hyperresponsiveness by lovastatin in mice.
    Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi, 2008, Volume: 44, Issue:3-4

    Topics: Acetylcholine; Animals; Antigens; Asthma; Atropine; Bronchial Hyperreactivity; Bronchodilator Agents

2008
Allergic sensitization enhances anion current responsiveness of murine trachea to PAR-2 activation.
    Pflugers Archiv : European journal of physiology, 2012, Volume: 463, Issue:3

    Topics: Amiloride; Animals; Asthma; Benzoates; Bestrophins; Chloride Channels; Eye Proteins; Hypersensitivit

2012
Relaxant effect of oxygen free radicals on rabbit tracheal smooth muscle.
    Pulmonary pharmacology & therapeutics, 2002, Volume: 15, Issue:4

    Topics: Analysis of Variance; Animals; Asthma; Cyclooxygenase Inhibitors; Epithelium; Hydrogen Peroxide; Hyd

2002
Effects of non-steroidal anti-inflammatory drugs on cyclo-oxygenase and lipoxygenase activity in whole blood from aspirin-sensitive asthmatics vs healthy donors.
    British journal of pharmacology, 2002, Volume: 137, Issue:7

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Benzene Derivatives; Calcimycin; Cyclooxyg

2002
Role of cyclooxygenase activation and prostaglandins in antigen-induced excitability changes of bronchial parasympathetic ganglia neurons.
    American journal of physiology. Lung cellular and molecular physiology, 2003, Volume: 284, Issue:4

    Topics: Action Potentials; Animals; Asthma; Bronchi; Bronchoconstriction; Cyclooxygenase Inhibitors; Dinopro

2003
Deficient prostaglandin E2 production by bronchial fibroblasts of asthmatic patients, with special reference to aspirin-induced asthma.
    The Journal of allergy and clinical immunology, 2003, Volume: 111, Issue:5

    Topics: Adult; Aged; Aspirin; Asthma; Bronchi; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Dinopros

2003
Isoquercitrin from Argemone platyceras inhibits carbachol and leukotriene D4-induced contraction in guinea-pig airways.
    European journal of pharmacology, 2005, Oct-17, Volume: 522, Issue:1-3

    Topics: Acetates; Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Argemone; Asthma;

2005
Prostaglandin involvement in lung C-fiber activation by substance P in guinea pigs.
    Journal of applied physiology (Bethesda, Md. : 1985), 2006, Volume: 100, Issue:6

    Topics: Action Potentials; Adrenergic beta-Antagonists; Animals; Asthma; Blood Pressure; Bradykinin; Capsaic

2006
Discovery of potent CRTh2 (DP2) receptor antagonists.
    Bioorganic & medicinal chemistry letters, 2006, Aug-15, Volume: 16, Issue:16

    Topics: Asthma; Chemistry, Pharmaceutical; Drug Design; Humans; Indomethacin; Inflammation; Inhibitory Conce

2006
Bronchial asthma induced by indomethacin.
    Annals of internal medicine, 1967, Volume: 66, Issue:3

    Topics: Aspirin; Asthma; Dextropropoxyphene; Drug Hypersensitivity; Humans; Indomethacin; Male; Middle Aged;

1967
The evolution and future horizons of research on the metabolism of arachidonic acid by 5-lipoxygenase.
    The Journal of allergy and clinical immunology, 1984, Volume: 74, Issue:3 Pt 2

    Topics: Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Asthma; Epoprostenol; Huma

1984
Mexican drug therapy.
    Clinical toxicology, 1980, Volume: 17, Issue:1

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Amygdalin; Arthritis; Asthma; Diazepam; Female; Histamin

1980
Slow-reacting substance from alveolar macrophages--a mechanism of asthma?
    The Australian journal of experimental biology and medical science, 1981, Volume: 59, Issue:4

    Topics: Animals; Asthma; Atropine; Autacoids; Chromones; Cimetidine; Ethers; Guinea Pigs; Indomethacin; Macr

1981
Interactions between beta-adrenergic activity and prostaglandin synthesis in control of airways bronchoconstrictor responsiveness.
    Agents and actions. Supplements, 1983, Volume: 13

    Topics: Adult; Airway Resistance; Albuterol; Asthma; Bronchi; Female; Histamine; Humans; Indomethacin; Male;

1983
Implications of NSAID effects during allergen-induced bronchospasm.
    Agents and actions. Supplements, 1983, Volume: 13

    Topics: Allergens; Anti-Inflammatory Agents; Asthma; Bronchi; Humans; Indomethacin; Mites; Propionates

1983
Indomethacin potentiates the pulmonary response to aerosol leukotriene C4 in the guinea pig.
    The American review of respiratory disease, 1983, Volume: 128, Issue:4

    Topics: Aerosols; Animals; Asthma; Bronchi; Dose-Response Relationship, Drug; Drug Synergism; Guinea Pigs; I

1983
Intrinsic and extrinsic asthma, a shared lymphocyte abnormality.
    Clinical allergy, 1983, Volume: 13, Issue:6

    Topics: Adult; Aged; Asthma; Bronchitis; Concanavalin A; Humans; Indomethacin; Lymphocyte Activation; Middle

1983
Aspirin tolerance induced in aspirin-sensitive asthmatics.
    Allergy, 1984, Volume: 39, Issue:3

    Topics: Aspirin; Asthma; Cross Reactions; Dose-Response Relationship, Drug; Dose-Response Relationship, Immu

1984
Aspirin desensitization in aspirin-sensitive asthma: failure to maintain a desensitized state during prolonged therapy.
    The American review of respiratory disease, 1984, Volume: 129, Issue:6

    Topics: Adult; Aspirin; Asthma; Cross Reactions; Desensitization, Immunologic; Female; Humans; Indomethacin;

1984
Evidence for lipoxygenase pathway involvement in allergic tracheal contraction.
    Prostaglandins, 1980, Volume: 19, Issue:4

    Topics: Animals; Arachidonic Acids; Aspirin; Asthma; Constriction, Pathologic; Guinea Pigs; Histamine; Hyper

1980
[Prevention of food hypersensitivities with aspirin].
    MMW, Munchener medizinische Wochenschrift, 1980, Jul-18, Volume: 122, Issue:29

    Topics: Animals; Arachidonic Acids; Aspirin; Asthma; Food Hypersensitivity; Ibuprofen; Indomethacin; Milk; P

1980
An inhibitor of the lipoxygenase and cyclooxygenase pathways of arachidonic acid, 5, 8, 11, 14-eicosatetraynoic acid, inhibits immunoglobulin E mediated antigen induced monkey asthma and skin reactions.
    Transactions of the Association of American Physicians, 1980, Volume: 93

    Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonate Lipoxygenases; Asthma; Cyclooxygenase Inhibit

1980
Effect of ascorbic acid on response to methacholine challenge in asthmatic subjects.
    The American review of respiratory disease, 1983, Volume: 127, Issue:2

    Topics: Adult; Airway Resistance; Ascorbic Acid; Asthma; Bronchial Provocation Tests; Dose-Response Relation

1983
The late reaction following bronchial provocation with house dust mite allergen. Dependence on arachidonic acid metabolism.
    Clinical and experimental immunology, 1983, Volume: 52, Issue:2

    Topics: Adolescent; Adult; Allergens; Arachidonic Acids; Asthma; Bronchial Provocation Tests; Bronchial Spas

1983
Aspirin desensitization in aspirin-sensitive asthmatic patients: clinical manifestations and characterization of the refractory period.
    The Journal of allergy and clinical immunology, 1982, Volume: 69, Issue:1 Pt 1

    Topics: Adolescent; Adult; Aged; Aspirin; Asthma; Desensitization, Immunologic; Dose-Response Relationship,

1982
Spontaneous activity in the trachea of dogs treated with indomethacin: an experimental model for aspirin-related asthma.
    British journal of pharmacology, 1981, Volume: 73, Issue:2

    Topics: Animals; Aspirin; Asthma; Atropine; Disease Models, Animal; Dogs; Female; Indomethacin; Male; Muscle

1981
Indomethacin modification of immediate-type immunologic airway responses in allergic asthmatic and non-asthmatic subjects: evidence for altered arachidonic acid metabolism in asthma.
    The American review of respiratory disease, 1981, Volume: 123, Issue:6

    Topics: Adult; Airway Resistance; Arachidonic Acids; Asthma; Dose-Response Relationship, Drug; Female; Human

1981
Prostaglandins in exercise-induced asthma.
    Clinical allergy, 1981, Volume: 11, Issue:5

    Topics: Asthma; Asthma, Exercise-Induced; Child; Forced Expiratory Volume; Humans; Indomethacin; Prostagland

1981
Bradykinin-induced airway inflammation. Contribution of sensory neuropeptides differs according to airway site.
    American journal of respiratory and critical care medicine, 1994, Volume: 149, Issue:3 Pt 1

    Topics: Animals; Asthma; Atropine; Bradykinin; Capillary Permeability; Dipeptides; Evans Blue; Guinea Pigs;

1994
Inhibitory effect of DS-4574 on leukotriene- or antigen-induced bronchoconstriction in guinea pigs.
    International archives of allergy and immunology, 1993, Volume: 100, Issue:3

    Topics: Animals; Antigens; Asthma; Atropine; Bronchoconstriction; Guinea Pigs; Histamine Release; Immunizati

1993
Effect of anti-inflammatory agent etodolac on antigen-induced contractions of the trachea and lung parenchyma of guinea pigs.
    Prostaglandins, leukotrienes, and essential fatty acids, 1994, Volume: 51, Issue:6

    Topics: Animals; Asthma; Benzoquinones; Disease Models, Animal; Etodolac; Guinea Pigs; Immunization, Passive

1994
Potential species dependency for the pulmonary antiallergic effects of aerosolized heparin.
    Pulmonary pharmacology, 1993, Volume: 6, Issue:4

    Topics: Administration, Inhalation; Aerosols; Animals; Antigens; Asthma; Bronchoconstriction; Guinea Pigs; H

1993
Effects of CS-518, a thromboxane synthase inhibitor, on the asthmatic response.
    European journal of pharmacology, 1993, May-12, Volume: 236, Issue:1

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Asthma; Bronchial Hyper

1993
[Hypertonic saline induced bronchoconstriction in sensitized rabbits].
    Nihon Kyobu Shikkan Gakkai zasshi, 1996, Volume: 34, Issue:5

    Topics: Animals; Asthma; Atropine; Bronchoconstriction; Chlorpheniramine; Cholinergic Antagonists; Cyclooxyg

1996
Acute bronchial asthma associated with the administration of ophthalmic indomethacin.
    Israel journal of medical sciences, 1996, Volume: 32, Issue:11

    Topics: Acute Disease; Aged; Asthma; Cataract Extraction; Humans; Indomethacin; Male; Postoperative Period;

1996
Effect of combined leukotriene D(4) and thromboxane A(2) receptor antagonist on mediator-controlled resistance in guinea pigs.
    European journal of pharmacology, 2000, Sep-01, Volume: 403, Issue:1-2

    Topics: Administration, Oral; Airway Resistance; Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents, N

2000
Eicosanoid and muscarinic receptor blockade abolishes hyperventilation-induced bronchoconstriction.
    Journal of applied physiology (Bethesda, Md. : 1985), 2000, Volume: 89, Issue:5

    Topics: Animals; Arachidonate 5-Lipoxygenase; Asthma; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Cyc

2000
Cyclooxygenase metabolites play a different role in ozone-induced pulmonary function decline in asthmatics compared to normals.
    Inhalation toxicology, 2000, Volume: 12, Issue:12

    Topics: Adolescent; Adult; Asthma; Dinoprost; Female; Humans; Indomethacin; Lung; Male; Ozone; Prostaglandin

2000
Role of chemical mediators in airway hyperresponsiveness in an asthmatic model.
    Respiration; international review of thoracic diseases, 2001, Volume: 68, Issue:1

    Topics: Airway Resistance; Animals; Asthma; Bronchial Hyperreactivity; Disease Models, Animal; Dose-Response

2001
Pharmacology of Schultz-Dale reaction in canine lung strip in vitro: possible model for allergic asthma.
    British journal of pharmacology, 1979, Volume: 66, Issue:4

    Topics: Anaphylaxis; Animals; Asthma; Autacoids; Disease Models, Animal; Dogs; Female; Histamine H1 Antagoni

1979
Letter: Prostaglandins and asthma.
    Lancet (London, England), 1975, Jan-04, Volume: 1, Issue:7897

    Topics: Antigens; Asthma; Humans; Indomethacin; Muscle Contraction; Muscles; Physical Exertion; Prostaglandi

1975
Letter: Prostaglandins and asthma.
    Lancet (London, England), 1975, Feb-15, Volume: 1, Issue:7903

    Topics: Animals; Asthma; Guinea Pigs; Humans; Indomethacin; Muscle Contraction; Prostaglandins; Spirometry;

1975
Bronchial and intravenous provocation tests with indomethacin in aspirin-sensitive asthmatics.
    The American review of respiratory disease, 1979, Volume: 120, Issue:5

    Topics: Adult; Aspirin; Asthma; Bronchial Provocation Tests; Cromolyn Sodium; Female; Humans; Indomethacin;

1979
[Salicylamide-- a potential pain-remedy alternative in the analgesic asthma syndrome].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1979, Dec-01, Volume: 34, Issue:23

    Topics: Analgesics; Animals; Antipyrine; Asthma; Bronchial Spasm; Cyclooxygenase Inhibitors; Female; Guinea

1979
[Experimental investigation on pathogenesis of indomethacin-induced asthma--effect of indomethacin on the action of various bronchodilators (author's transl)].
    Nihon Kyobu Shikkan Gakkai zasshi, 1979, Volume: 17, Issue:2

    Topics: Animals; Asthma; Bronchodilator Agents; Guinea Pigs; In Vitro Techniques; Indomethacin; Isoprotereno

1979
Experimental investigation on the pathogenesis of tartrazine-induced asthma.
    The Tohoku journal of experimental medicine, 1979, Volume: 129, Issue:3

    Topics: Animals; Asthma; Azo Compounds; Bronchodilator Agents; Dose-Response Relationship, Drug; Drug Synerg

1979
Indomethacin-induced asthma in aspirin-sensitive patients.
    British medical journal, 1977, Nov-12, Volume: 2, Issue:6097

    Topics: Adult; Aspirin; Asthma; Female; Humans; Indomethacin

1977
Treatment of chronic airways obstruction with indomethacin.
    Scandinavian journal of respiratory diseases, 1977, Volume: 58, Issue:5

    Topics: Aged; Asthma; Chronic Disease; Drug Evaluation; Female; Humans; Indomethacin; Male; Middle Aged

1977
[Indomethacin-induced asthma (author's transl)].
    Nihon Kyobu Shikkan Gakkai zasshi, 1977, Volume: 15, Issue:10

    Topics: Adult; Aspirin; Asthma; Female; Humans; Indomethacin; Male; Middle Aged

1977
Failure of hypoxic pulmonary vasoconstriction in the canine asthma model. Effect of prostaglandin inhibitors.
    The Journal of clinical investigation, 1978, Volume: 61, Issue:6

    Topics: Animals; Ascaris; Aspirin; Asthma; Dogs; Hypersensitivity; Hypoxia; Indomethacin; Lung; Oxygen; Pros

1978
[A case report of indomethacin induced asthma with special reference to prostaglandins metabolism in the lungs (author's transl)].
    Nihon Kyobu Shikkan Gakkai zasshi, 1978, Volume: 16, Issue:5

    Topics: Adult; Asthma; Female; Humans; Indomethacin; Lung; Prostaglandins E

1978
Asthma relieved by aspirin and by other cyclo-oxygenase inhibitors.
    Thorax, 1978, Volume: 33, Issue:5

    Topics: Aspirin; Asthma; Fenoprofen; Humans; Indomethacin; Male; Mefenamic Acid; Middle Aged

1978
Inhibitory effects of various drugs on dual asthmatic responses in wheat flour-sensitive subjects.
    The Journal of allergy and clinical immunology, 1976, Volume: 58, Issue:1 PT 1

    Topics: Adrenal Cortex Hormones; Adult; Aspirin; Asthma; Cromolyn Sodium; Diethylcarbamazine; Flour; Forced

1976
Effect of indomethacin and atropine in experimental asthma in conscious guinea pigs.
    Journal of applied physiology, 1976, Volume: 40, Issue:6

    Topics: Aerosols; Airway Resistance; Animals; Antigens; Asthma; Atropine; Guinea Pigs; Horseradish Peroxidas

1976
Acute respiratory failure secondary to indomethacin in an aspirin-intolerant asthmatic patient.
    Annals of allergy, 1976, Volume: 37, Issue:2

    Topics: Acute Disease; Aspirin; Asthma; Drug Hypersensitivity; Humans; Indomethacin; Male; Middle Aged; Resp

1976
Aspects of prostaglandin action in asthma.
    Advances in prostaglandin and thromboxane research, 1976, Volume: 1

    Topics: Adult; Allergens; Asthma; Cortisone; Female; Heparin; Humans; Indomethacin; Male; Physical Exertion;

1976
Relationship of inhibition of prostaglandin biosynthesis by analgesics to asthma attacks in aspirin-sensitive patients.
    British medical journal, 1975, Jan-11, Volume: 1, Issue:5949

    Topics: Adult; Aged; Analgesics; Aspirin; Asthma; Bronchi; Drug Hypersensitivity; Female; Flufenamic Acid; H

1975
[Advances in pneumonology. Aspirin-induced asthma].
    Polskie Archiwum Medycyny Wewnetrznej, 1975, Volume: 54, Issue:6

    Topics: Adult; Age Factors; Aspirin; Asthma; Depression, Chemical; Drug Hypersensitivity; Humans; Indomethac

1975
Prostaglandins and asthma.
    British journal of clinical pharmacology, 1975, Volume: 2, Issue:4

    Topics: Aerosols; Animals; Asthma; Bronchi; Bronchodilator Agents; Humans; Indomethacin; Infusions, Parenter

1975
Involvement of arachidonate cyclooxygenase products in bronchial hyperresponsiveness induced by subthreshold concentration of aerosolized thromboxane A2 analogue (STA2) in guinea pigs.
    Allergy, 1992, Volume: 47, Issue:2 Pt 2

    Topics: Aerosols; Animals; Asthma; Bronchial Hyperreactivity; Bronchoconstriction; Dose-Response Relationshi

1992
Basophil histamine release by platelet-activating factor in aspirin-sensitive subjects with asthma.
    The Journal of allergy and clinical immunology, 1990, Volume: 86, Issue:4 Pt 1

    Topics: Adult; Aged; Aspirin; Asthma; Basophils; Cytochalasin B; Dexamethasone; Female; Histamine Release; H

1990
The interaction of acetylcholine and histamine on human bronchial smooth muscle contraction.
    The European respiratory journal, 1991, Volume: 4, Issue:8

    Topics: Acetylcholine; Asthma; Atropine; Bronchi; Dose-Response Relationship, Drug; Drug Interactions; Epith

1991
[Acute myocardial injury and repeated angina pectoris-like attacks in a young patient with Churg-Strauss syndrome].
    Nihon Kyobu Shikkan Gakkai zasshi, 1991, Volume: 29, Issue:12

    Topics: Adult; Age Factors; Angina Pectoris; Aspirin; Asthma; Churg-Strauss Syndrome; Eosinophilia; Humans;

1991
Effect of the selective PAF antagonist SM-10661 on an asthmatic model. 1. Effect on passive anaphylactic bronchoconstriction in guinea pigs.
    Lipids, 1991, Volume: 26, Issue:12

    Topics: Anaphylaxis; Animals; Asthma; Bronchoconstriction; Disease Models, Animal; Dose-Response Relationshi

1991
Formation of PGD2 after allergen inhalation in atopic asthmatics.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1991, Volume: 21A

    Topics: Allergens; Asthma; Cyclooxygenase Inhibitors; Double-Blind Method; Forced Expiratory Volume; Hyperse

1991
[Effects of phospholipid platelet activation factor on proliferation of B-lymphocytes of the peripheral blood of healthy donors and patients with bronchial asthma].
    Biulleten' eksperimental'noi biologii i meditsiny, 1991, Volume: 111, Issue:4

    Topics: Adult; Asthma; B-Lymphocytes; Cell Division; Cells, Cultured; Female; Humans; Immunoglobulin E; Immu

1991
Muscarinic-receptor functioning in tracheas from normal and ovalbumin-sensitive guinea pigs.
    Canadian journal of physiology and pharmacology, 1991, Volume: 69, Issue:6

    Topics: Aerosols; Animals; Asthma; Bethanidine; Electric Stimulation; Female; Gallamine Triethiodide; Guinea

1991
Aspirin-sensitive asthma: significance of the cyclooxygenase-inhibiting and protein-binding properties of analgesic drugs.
    International archives of allergy and applied immunology, 1991, Volume: 95, Issue:4

    Topics: Acetaminophen; Administration, Inhalation; Adult; Aged; Aspirin; Asthma; Dinoprost; Drug Tolerance;

1991
Epithelium-derived inhibitory factor in human bronchus.
    European journal of pharmacology, 1990, Oct-23, Volume: 187, Issue:3

    Topics: Animals; Asthma; Biological Factors; Bronchi; Carbachol; Histamine; Humans; In Vitro Techniques; Ind

1990
Mechanisms of decrease in cytoplasmic motility of alveolar macrophages during immediate asthmatic response in dogs.
    The American journal of physiology, 1990, Volume: 258, Issue:4 Pt 1

    Topics: Aerosols; Alprostadil; Animals; Antigens, Helminth; Ascaris; Asthma; Carbon Dioxide; Cytoplasm; Dicl

1990
[Eicosanoids in bronchial asthma].
    Nihon rinsho. Japanese journal of clinical medicine, 1990, Volume: 48, Issue:6

    Topics: Acrylates; Arachidonic Acids; Asthma; Benzoquinones; Bronchoalveolar Lavage Fluid; Chromones; Cycloo

1990
Anaphylactic challenge causes eosinophil accumulation in bronchoalveolar lavage fluid of guinea pigs. Modulation by betamethasone, phenidone, indomethacin, WEB 2086, and a novel antiallergy agent, SCH 37224.
    The American review of respiratory disease, 1990, Volume: 142, Issue:3

    Topics: Albumins; Anaphylaxis; Animals; Asthma; Azepines; Betamethasone; Bronchoalveolar Lavage Fluid; Cell

1990
Attenuating effect of a thromboxane synthetase inhibitor (OKY-046) on bronchial responsiveness to methacholine is specific to bronchial asthma.
    Chest, 1990, Volume: 98, Issue:3

    Topics: Acrylates; Asthma; Bronchi; Bronchial Provocation Tests; Bronchiectasis; Bronchitis; Female; Forced

1990
Responses of equine trachealis and lung parenchyma to methacholine, histamine, serotonin, prostanoids, and leukotrienes in vitro.
    Canadian journal of physiology and pharmacology, 1990, Volume: 68, Issue:3

    Topics: Animals; Asthma; Atropine; Disease Models, Animal; Histamine; Horses; In Vitro Techniques; Indometha

1990
Abnormal platelet hydrogen peroxide metabolism in aspirin hypersensitivity.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1990, Volume: 20, Issue:2

    Topics: Aspirin; Asthma; Blood Platelets; Drug Hypersensitivity; Glutathione Peroxidase; Humans; Hydrogen Pe

1990
Effect of OKY-046, a new thromboxane A2 synthetase inhibitor, on experimental asthma in guinea pigs.
    Prostaglandins, leukotrienes, and medicine, 1987, Volume: 30, Issue:2-3

    Topics: Acrylates; Animals; Asthma; Female; Guinea Pigs; Histamine; Histamine Release; Indomethacin; Lung; M

1987
On the mechanism of aspirin asthma.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1989, Volume: 19

    Topics: Aspirin; Asthma; Humans; In Vitro Techniques; Indomethacin; Leukotrienes; Lung; Lysine

1989
Inhibitability and enhanceability of basophil histamine release in asthmatic and normal subjects.
    International archives of allergy and applied immunology, 1985, Volume: 76, Issue:4

    Topics: Adolescent; Adult; Asthma; Basophils; Bronchial Provocation Tests; Female; Histamine Release; Humans

1985
A possible role for PAF in allergen-induced late responses: modification by a selective antagonist.
    Journal of applied physiology (Bethesda, Md. : 1985), 1989, Volume: 66, Issue:5

    Topics: Aerosols; Allergens; Animals; Antigens, Helminth; Ascaris; Asthma; Azepines; Chlorpheniramine; Chrom

1989
Acute asthma attack due to ophthalmic indomethacin.
    Annals of internal medicine, 1989, Aug-15, Volume: 111, Issue:4

    Topics: Aged; Albuterol; Asthma; Combined Modality Therapy; Female; Glucocorticoids; Humans; Indomethacin; O

1989
Human isolated bronchial muscle preparations from asthmatic patients: effects of indomethacin and contractile agonists.
    Prostaglandins, 1989, Volume: 37, Issue:4

    Topics: Acetylcholine; Asthma; Bronchi; Dinoprost; Dinoprostone; Histamine; Humans; In Vitro Techniques; Ind

1989
Effects of antigen on tracheal circulation and smooth muscle in sheep of different ages.
    Journal of applied physiology (Bethesda, Md. : 1985), 1989, Volume: 67, Issue:3

    Topics: Age Factors; Animals; Antigens, Helminth; Ascaris; Asthma; Female; Indomethacin; Male; Muscle Contra

1989
Role of arachidonic acid metabolites in beta-adrenergic desensitization in lungs.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1987, Volume: 17B

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Asthma; Guinea Pigs; Indomethacin; Isoproterenol; Lung

1987
[Occurrence of drug reactions].
    Bollettino dell'Istituto sieroterapico milanese, 1986, Volume: 65, Issue:1

    Topics: Acetaminophen; Adult; Anaphylaxis; Angioedema; Aspirin; Asthma; Drug Hypersensitivity; Emergencies;

1986
Increased activity of 5-lipoxygenase in polymorphonuclear leukocytes from asthmatic patients.
    Life sciences, 1985, Sep-09, Volume: 37, Issue:10

    Topics: Adult; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Asthma; Calcium; Chromatogra

1985
[Effect of indomethacin on beta adrenergic receptor function in bronchial asthma].
    Orvosi hetilap, 1986, Oct-12, Volume: 127, Issue:41

    Topics: Adult; Asthma; Female; Humans; Indomethacin; Male; Receptors, Adrenergic, beta

1986
Pharmacological characterization of airway smooth muscle responses to antigen in ascaris-sensitive dogs.
    Canadian journal of physiology and pharmacology, 1986, Volume: 64, Issue:11

    Topics: 5,8,11,14-Eicosatetraynoic Acid; Acetylcholine; Airway Resistance; Animals; Antigens, Helminth; Arac

1986
[The role of arachidonic acid metabolites on bronchial hyperresponsiveness to acetylcholine in asthmatic patients].
    Arerugi = [Allergy], 1986, Volume: 35, Issue:9

    Topics: Acetylcholine; Adult; Aged; Arachidonic Acid; Arachidonic Acids; Asthma; Bronchi; Bronchial Provocat

1986
Mechanism of platelet activating factor-induced bronchoconstriction in humans.
    The American review of respiratory disease, 1988, Volume: 137, Issue:5

    Topics: Adolescent; Adult; Asthma; Atropine; Bronchi; Bronchial Provocation Tests; Chlorpheniramine; Dose-Re

1988
Regional differences in the mechanical properties of rabbit airway smooth muscle.
    British journal of pharmacology, 1988, Volume: 94, Issue:2

    Topics: Acetylcholine; Animals; Asthma; Bronchi; Histamine; In Vitro Techniques; Indomethacin; Male; Muscle

1988
Ciliary responsiveness in allergic and nonallergic airways.
    Journal of applied physiology (Bethesda, Md. : 1985), 1986, Volume: 60, Issue:6

    Topics: Alprostadil; Animals; Ascaris; Asthma; Cilia; Dinoprostone; Dose-Response Relationship, Drug; Epithe

1986
Tolerance to acetylsalicylic acid (ASA) induced in ASA-sensitive asthmatics does not depend on initial adverse reaction.
    Allergy, 1987, Volume: 42, Issue:3

    Topics: Adult; Aspirin; Asthma; Desensitization, Immunologic; Drug Hypersensitivity; Drug Tolerance; Female;

1987
Effect of macrophage stimulation on parasympathetic airway contraction in dogs.
    European journal of pharmacology, 1987, Jun-26, Volume: 138, Issue:3

    Topics: Animals; Asthma; Bridged Bicyclo Compounds, Heterocyclic; Bronchi; Dogs; Electric Stimulation; Fatty

1987
Differential effects of epithelium removal on the responsiveness of guinea-pig tracheal smooth muscle to bronchoconstrictors.
    British journal of pharmacology, 1987, Volume: 92, Issue:2

    Topics: Animals; Asthma; Bronchi; Epithelium; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Muscle C

1987
Tachyphylaxis to inhaled histamine in asthmatic subjects.
    Journal of applied physiology (Bethesda, Md. : 1985), 1987, Volume: 63, Issue:4

    Topics: Acetylcholine; Administration, Inhalation; Adolescent; Adult; Asthma; Bronchial Provocation Tests; F

1987
[Development of aspirin tolerance in hypersensitive persons. I. Methods of development of tolerance, aspirin refraction time and cross tolerance to other drugs].
    Polskie Archiwum Medycyny Wewnetrznej, 1986, Volume: 75, Issue:1

    Topics: Antipyrine; Aspirin; Asthma; Cross Reactions; Drug Hypersensitivity; Drug Tolerance; Humans; Indomet

1986
[Immunomodulating therapy with indomethacin and levamisole in patients with chronic bronchitis and bronchial asthma].
    Klinicheskaia meditsina, 1985, Volume: 63, Issue:6

    Topics: Adult; Asthma; Bronchitis; Chronic Disease; Drug Therapy, Combination; Female; Humans; Indomethacin;

1985
[Demonstration of specific platelet function anomaly in asthma induced by aspirin: diagnostic consequences].
    Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie, 1985, Volume: 300, Issue:4

    Topics: Aspirin; Asthma; Blood Platelets; Cyclooxygenase Inhibitors; Female; Humans; Indomethacin; Male; Pro

1985
Non-steroid anti-inflammatory drugs in asthma: dangerous or useful therapy?
    Allergy, 1985, Volume: 40, Issue:3

    Topics: Adolescent; Adult; Allergens; Animals; Arachidonic Acid; Arachidonic Acids; Asthma; Cats; Dust; Fema

1985
Leukotrienes (LTC4, LTD4) confer glass non-adherence on leukocytes of asthmatic individuals. Dependency on cyclooxygenase products and calcium ion.
    Immunology letters, 1985, Volume: 10, Issue:6

    Topics: Asthma; Calcium; Cell Adhesion; Child; Cyclooxygenase Inhibitors; Dinoprostone; Glass; Humans; Indom

1985
[Inhibitory effects of various drugs on histamine or allergen-induced bronchoconstriction].
    Nihon Kyobu Shikkan Gakkai zasshi, 1985, Volume: 23, Issue:10

    Topics: Adolescent; Adult; Aged; Animals; Asthma; Diethylcarbamazine; Drug Evaluation; Female; Guinea Pigs;

1985
[Intravenous indomethacin in therapy of rheumatic diseases and other morbid conditions].
    La Clinica terapeutica, 1972, Jan-15, Volume: 60, Issue:1

    Topics: Adult; Aged; Arthritis, Rheumatoid; Asthma; Female; Gout; Humans; Indomethacin; Male; Middle Aged; O

1972
[Bronchial asthma, a side effect of indomethacin which can be avoided].
    Nederlands tijdschrift voor geneeskunde, 1973, Jun-02, Volume: 117, Issue:22

    Topics: Adult; Aspirin; Asthma; Humans; Indomethacin; Male; Nasal Polyps

1973
Aspirin and other cross-reacting small chemicals in known aspirin intolerant patients.
    Annals of allergy, 1973, Volume: 31, Issue:10

    Topics: Analgesics; Antioxidants; Aspirin; Asthma; Blood Coagulation; Cross Reactions; Dose-Response Relatio

1973
Concerning the nature of intolerance to aspirin.
    The Journal of allergy, 1967, Volume: 40, Issue:5

    Topics: Aminopyrine; Antipyrine; Aspirin; Asthma; Chemoreceptor Cells; Drug Hypersensitivity; Edema; Histami

1967
[Clinical observations on the treatment of rheumatic diseases and other morbid states with indomethacin].
    Minerva medica, 1966, Nov-17, Volume: 57, Issue:92

    Topics: Anemia, Hemolytic, Autoimmune; Arthritis, Rheumatoid; Asthma; Crohn Disease; Dexamethasone; Hodgkin

1966
Response of aspirin-allergic patients to challenge by some analgesics in common use.
    British medical journal, 1971, May-29, Volume: 2, Issue:5760

    Topics: Acetaminophen; Adult; Analgesics; Aspirin; Asthma; Dextropropoxyphene; Drug Hypersensitivity; Female

1971