Page last updated: 2024-10-29

indomethacin and Asphyxia Neonatorum

indomethacin has been researched along with Asphyxia Neonatorum in 7 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Asphyxia Neonatorum: Respiratory failure in the newborn. (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
" Indomethacin given at therapeutic dosage before asphyxia/reventilation decreased superoxide anion production to 3 +/- 1 pmol NBT/mm2 per 20 min, values not significantly different from the control group and from piglets pretreated with oxypurinol at a dose of 50 mg/kg i."1.29Brain superoxide anion generation in asphyxiated piglets and the effect of indomethacin at therapeutic dose. ( Bada, HS; Busija, DW; Korones, SB; Leffler, CW; Pourcyrous, M, 1993)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19904 (57.14)18.7374
1990's3 (42.86)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topalian, SL1
Ziegler, MM1
Guignard, JP1
Oh, W1
Pomphrey, MA1
Zuckerman, S1
Shibata, M1
Leffler, CW2
Pourcyrous, M1
Bada, HS1
Korones, SB1
Busija, DW1
Shadid, M1
Moison, R1
Steendijk, P1
Hiltermann, L1
Berger, HM1
van Bel, F1
Chemtob, S1
Laudignon, N1
Aranda, JV1

Reviews

2 reviews available for indomethacin and Asphyxia Neonatorum

ArticleYear
Necrotizing enterocolitis: a review of animal models.
    The Journal of surgical research, 1984, Volume: 37, Issue:4

    Topics: Animals; Animals, Newborn; Asphyxia Neonatorum; Bacterial Physiological Phenomena; Blood Volume; Bre

1984
Drug therapy in hypoxic-ischemic cerebral insults and intraventricular hemorrhage of the newborn.
    Clinics in perinatology, 1987, Volume: 14, Issue:4

    Topics: Asphyxia Neonatorum; Barbiturates; Brain Ischemia; Cerebral Hemorrhage; Female; Fetal Hypoxia; Human

1987

Other Studies

5 other studies available for indomethacin and Asphyxia Neonatorum

ArticleYear
Drugs and the neonatal kidney.
    Developmental pharmacology and therapeutics, 1982, Volume: 4 Suppl

    Topics: Asphyxia Neonatorum; Captopril; Gentamicins; Humans; Hypoxia; Indomethacin; Infant, Newborn; Infant,

1982
Renal functions and clinical disorders in the neonate.
    Clinics in perinatology, 1981, Volume: 8, Issue:2

    Topics: Acute Kidney Injury; Anti-Bacterial Agents; Asphyxia Neonatorum; Furosemide; Humans; Indomethacin; I

1981
Effect of indomethacin on piglet cerebral blood flow following total cerebral ischemia.
    Journal of the Tennessee Medical Association, 1994, Volume: 87, Issue:5

    Topics: Animals; Animals, Newborn; Asphyxia Neonatorum; Brain; Brain Ischemia; Female; Humans; Indomethacin;

1994
Brain superoxide anion generation in asphyxiated piglets and the effect of indomethacin at therapeutic dose.
    Pediatric research, 1993, Volume: 34, Issue:3

    Topics: Animals; Animals, Newborn; Asphyxia Neonatorum; Blood Pressure; Cerebral Cortex; Disease Models, Ani

1993
The effect of antioxidative combination therapy on post hypoxic-ischemic perfusion, metabolism, and electrical activity of the newborn brain.
    Pediatric research, 1998, Volume: 44, Issue:1

    Topics: Allopurinol; Animals; Animals, Newborn; Antioxidants; Asphyxia Neonatorum; Brain; Brain Ischemia; Cy

1998