Page last updated: 2024-10-29

indomethacin and Apnea

indomethacin has been researched along with Apnea in 7 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Apnea: A transient absence of spontaneous respiration.

Research Excerpts

ExcerptRelevanceReference
" These factors (immaturity, hyperoxia, hypoxia, blood transfusions, intraventricular hemorrhage, apnea, infection, hypercarbia, hypocarbia, patent ductus arteriosus, prostaglandin synthetase inhibitors, vitamin E deficiency, lactic acidosis, prenatal complications, genetic factors) may all be present in an infant."4.76A reexamination of the role of oxygen in retrolental fibroplasia. ( Dangman, B; Lucey, JF, 1984)
" The reflex apnea was significantly attenuated by N-acetyl-l-cysteine (antioxidant), EGTA (extracellular Ca(2+) chelator) and BAPTA-AM (intracellular Ca(2+) chelator), indicating the importance of reactive oxygen species (ROS) and Ca(2+)."3.79Role of TRPA1 and TRPV1 in the ROS-dependent sensory irritation of superior laryngeal capsaicin-sensitive afferents by cigarette smoke in anesthetized rats. ( Ho, CY; Kou, YR; Lai, CJ; Liu, BY; Lu, SH; Tsai, TL, 2013)
" Qualitative and quantitative differences in pharmacokinetics and pharmacodynamics of drugs should be considered before dosage regimens can be established."1.27[Peculiarities of drug therapy in childhood]. ( Kusenbach, G; Reinhardt, D, 1986)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19905 (71.43)18.7374
1990's1 (14.29)18.2507
2000's0 (0.00)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Liu, BY1
Tsai, TL1
Ho, CY1
Lu, SH1
Lai, CJ1
Kou, YR1
Lucey, JF1
Dangman, B1
Allen, LG1
Louis, TM1
Kopelman, AE1
Hammerman, C1
Zangen, D1
Bartel, J1
Müller, WD1
Zach, M1
Stix, H1
Rosegger, H1
Beitzke, A1
Reinhardt, D1
Kusenbach, G1

Reviews

2 reviews available for indomethacin and Apnea

ArticleYear
A reexamination of the role of oxygen in retrolental fibroplasia.
    Pediatrics, 1984, Volume: 73, Issue:1

    Topics: Anencephaly; Apnea; Carbon Dioxide; Cerebral Hemorrhage; Ductus Arteriosus, Patent; Exchange Transfu

1984
[Drug therapy of patent ductus arteriosus in premature and newborn infants].
    Kinderarztliche Praxis, 1978, Volume: 46, Issue:12

    Topics: Apnea; Aspirin; Chloroquine; Digitalis Glycosides; Ductus Arteriosus, Patent; Humans; Indomethacin;

1978

Other Studies

5 other studies available for indomethacin and Apnea

ArticleYear
Role of TRPA1 and TRPV1 in the ROS-dependent sensory irritation of superior laryngeal capsaicin-sensitive afferents by cigarette smoke in anesthetized rats.
    Pulmonary pharmacology & therapeutics, 2013, Volume: 26, Issue:3

    Topics: Acetanilides; Acetylcysteine; Animals; Antioxidants; Apnea; Calcium Channels; Capsaicin; Chelating A

2013
Brain prostaglandins E2 and F2 alpha following neonatal asphyxia in the guinea pig.
    Biology of the neonate, 1982, Volume: 42, Issue:1-2

    Topics: Animals; Animals, Newborn; Apnea; Asphyxia; Brain Chemistry; Guinea Pigs; Indomethacin; Prostaglandi

1982
Indomethacin and apnea of prematurity.
    Critical care medicine, 1993, Volume: 21, Issue:1

    Topics: Aminophylline; Apnea; Humans; Indomethacin; Infant, Newborn; Infant, Premature; Infant, Premature, D

1993
[Indomethacin in IRDS with PDA phenomenon (author's transl)].
    Klinische Padiatrie, 1979, Volume: 191, Issue:5

    Topics: Apnea; Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Respiratory Distress Syndro

1979
[Peculiarities of drug therapy in childhood].
    Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, 1986, Volume: 134, Issue:11

    Topics: Apnea; Biological Availability; Biotransformation; Caffeine; Child; Child, Preschool; Dexamethasone;

1986