indomethacin has been researched along with Aortic Coarctation in 6 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Aortic Coarctation: A birth defect characterized by the narrowing of the AORTA that can be of varying degree and at any point from the transverse arch to the iliac bifurcation. Aortic coarctation causes arterial HYPERTENSION before the point of narrowing and arterial HYPOTENSION beyond the narrowed portion.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with Tempo did not affect the arterial pressure of un-operated normotensive rats but promptly decreased the arterial pressure of rats with aortic coarctation-induced hypertension (from 178 +/- 2 to 125 +/- 6 mmHg)." | 5.32 | Prostaglandin I2 does not contribute to the hypotensive effect of the superoxide dismutase mimetic Tempo in rats with aortic coarctation-induced hypertension. ( DelliPizzi, A; Dinocca, S; Guan, H; Nasjletti, A, 2004) |
| "Treatment with Tempo did not affect the arterial pressure of un-operated normotensive rats but promptly decreased the arterial pressure of rats with aortic coarctation-induced hypertension (from 178 +/- 2 to 125 +/- 6 mmHg)." | 1.32 | Prostaglandin I2 does not contribute to the hypotensive effect of the superoxide dismutase mimetic Tempo in rats with aortic coarctation-induced hypertension. ( DelliPizzi, A; Dinocca, S; Guan, H; Nasjletti, A, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Golden-Plotnik, S | 1 |
| Rosenberg, HC | 1 |
| Altamirano-Diaz, LA | 1 |
| DelliPizzi, A | 2 |
| Guan, H | 1 |
| Dinocca, S | 1 |
| Nasjletti, A | 3 |
| Pucci, ML | 1 |
| Mosny, AY | 1 |
| Deseyn, K | 1 |
| Bobadilla, RA | 1 |
| Pérez-Alvarez, VM | 1 |
| López Sanchez, P | 1 |
| Castillo Henkel, C | 1 |
| Lin, L | 1 |
| Miller, MJ | 1 |
| Pinto, A | 1 |
| Mullane, KM | 1 |
6 other studies available for indomethacin and Aortic Coarctation
| Article | Year |
|---|---|
Indomethacin induced and prostaglandin relieved coarctation of the aorta in right aortic arch with left arterial duct: a case report.
Topics: Aorta, Thoracic; Aortic Coarctation; DiGeorge Syndrome; Ductus Arteriosus; Echocardiography, Doppler | 2017 |
Prostaglandin I2 does not contribute to the hypotensive effect of the superoxide dismutase mimetic Tempo in rats with aortic coarctation-induced hypertension.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Antihypertensive Agents; Aorta, Thoracic; Aortic Coarctation; | 2004 |
Contribution of constrictor prostanoids to the calcium-dependent basal tone in the aorta from rats with aortic coarctation-induced hypertension: relationship to nitric oxide.
Topics: Animals; Aorta, Thoracic; Aortic Coarctation; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Endo | 1997 |
Subrenal aorta coarctation of pregnant rats: changes in vascular contractility.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta, Thoracic; Aortic Coarctation; Dose-Response | 2000 |
Role of endothelium-derived prostanoid in angiotensin-induced vasoconstriction.
Topics: Acetylcholine; Analysis of Variance; Angiotensin II; Animals; Aorta; Aortic Coarctation; Bridged Bic | 1991 |
Impaired endothelium-dependent relaxations in rabbits subjected to aortic coarctation hypertension.
Topics: Acetylcholine; Animals; Aorta, Abdominal; Aorta, Thoracic; Aortic Coarctation; Calcimycin; Carotid A | 1987 |