indomethacin has been researched along with Anxiety in 12 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Anxiety: Feelings or emotions of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS.
Excerpt | Relevance | Reference |
---|---|---|
"To evaluate the effectiveness of a rectal nonsteroidal anti-inflammatory drug (indomethacin) for pain relief during a hysterosalpingography (HSG)." | 9.22 | Rectal indomethacin use in pain relief during hysterosalpingography: A randomized placebo controlled trial. ( Alkış, İ; Çim, N; Karaman, E; Yıldırım, A; Yıldızhan, R, 2016) |
"The mechanism underlying the previous findings that the development of antinociceptive tolerance to morphine was significantly delayed in the presence of inflammatory pain induced by formalin was examined." | 7.69 | Involvement of pain associated anxiety in the development of morphine tolerance in formalin treated mice. ( Kaneto, H; Rahman, AF; Takahashi, M, 1994) |
"To evaluate the effectiveness of a rectal nonsteroidal anti-inflammatory drug (indomethacin) for pain relief during a hysterosalpingography (HSG)." | 5.22 | Rectal indomethacin use in pain relief during hysterosalpingography: A randomized placebo controlled trial. ( Alkış, İ; Çim, N; Karaman, E; Yıldırım, A; Yıldızhan, R, 2016) |
" Rats received intra-VTA infusions of either PK11195 (400ng/mul, which inhibits de novo 3alpha,5alpha-THP production), indomethacin (10mug/mul, which blocks metabolism of P(4) to 3alpha,5alpha-THP), PK11195 and indomethacin together, or beta-cyclodextrin vehicle and tested on a battery of anxiety (open field and elevated plus maze), social (partner preference and social interaction), and sexual (paced mating) tasks." | 3.74 | Exploratory, anti-anxiety, social, and sexual behaviors of rats in behavioral estrus is attenuated with inhibition of 3alpha,5alpha-THP formation in the midbrain ventral tegmental area. ( Frye, CA; Paris, JJ; Rhodes, ME, 2008) |
"The mechanism underlying the previous findings that the development of antinociceptive tolerance to morphine was significantly delayed in the presence of inflammatory pain induced by formalin was examined." | 3.69 | Involvement of pain associated anxiety in the development of morphine tolerance in formalin treated mice. ( Kaneto, H; Rahman, AF; Takahashi, M, 1994) |
"In contrast, analgesia, sedation and catalepsy were not observed in this dose range, but were apparent at 100 mg/kg." | 1.33 | Pharmacological and pharmacokinetic characterization of the cannabinoid receptor 2 agonist, GW405833, utilizing rodent models of acute and chronic pain, anxiety, ataxia and catalepsy. ( Boulet, JM; Chaffer, SM; Elsemore, DA; Gottshall, SL; Harrison, JE; Koetzner, L; Lee, G; Mark, L; Miller, W; Pearson, MS; Rabadi, L; Rotshteyn, Y; Shan, S; Tafesse, L; Toth, M; Turchin, PI; Valenzano, KJ; Whiteside, GT, 2005) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 3 (25.00) | 18.7374 |
1990's | 2 (16.67) | 18.2507 |
2000's | 4 (33.33) | 29.6817 |
2010's | 3 (25.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Ferrer-Pérez, C | 1 |
Martinez, TE | 1 |
Montagud-Romero, S | 1 |
Ballestín, R | 1 |
Reguilón, MD | 1 |
Miñarro, J | 1 |
Rodríguez-Arias, M | 1 |
Thakre, PP | 1 |
Tundulwar, MR | 1 |
Chopde, CT | 1 |
Ugale, RR | 1 |
Karaman, E | 1 |
Çim, N | 1 |
Alkış, İ | 1 |
Yıldırım, A | 1 |
Yıldızhan, R | 1 |
Frye, CA | 2 |
Paris, JJ | 2 |
Rhodes, ME | 2 |
Valenzano, KJ | 1 |
Tafesse, L | 1 |
Lee, G | 1 |
Harrison, JE | 1 |
Boulet, JM | 1 |
Gottshall, SL | 1 |
Mark, L | 1 |
Pearson, MS | 1 |
Miller, W | 1 |
Shan, S | 1 |
Rabadi, L | 1 |
Rotshteyn, Y | 1 |
Chaffer, SM | 1 |
Turchin, PI | 1 |
Elsemore, DA | 1 |
Toth, M | 1 |
Koetzner, L | 1 |
Whiteside, GT | 1 |
Schwartz, JI | 1 |
Moura, RJ | 1 |
Gallo, MA | 1 |
Smith, SS | 1 |
Rahman, AF | 1 |
Takahashi, M | 1 |
Kaneto, H | 1 |
Lukács, H | 1 |
Friedman, AP | 1 |
McBride, WW | 1 |
Dodson, WH | 1 |
Bennett, JC | 1 |
1 trial available for indomethacin and Anxiety
Article | Year |
---|---|
Rectal indomethacin use in pain relief during hysterosalpingography: A randomized placebo controlled trial.
Topics: Administration, Rectal; Adult; Anti-Inflammatory Agents, Non-Steroidal; Anxiety; Depression; Female; | 2016 |
11 other studies available for indomethacin and Anxiety
Article | Year |
---|---|
Indomethacin blocks the increased conditioned rewarding effects of cocaine induced by repeated social defeat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anxiety; Brain; Cocaine; Cocaine-Related Disorders | 2018 |
Neurosteroid allopregnanolone attenuates development of nicotine withdrawal behavior in mice.
Topics: Animals; Anxiety; Finasteride; Indomethacin; Male; Maze Learning; Mice; Motor Activity; Neurotransmi | 2013 |
Exploratory, anti-anxiety, social, and sexual behaviors of rats in behavioral estrus is attenuated with inhibition of 3alpha,5alpha-THP formation in the midbrain ventral tegmental area.
Topics: Animals; Antineoplastic Agents; Anxiety; Behavior, Animal; Cyclooxygenase Inhibitors; Desoxycorticos | 2008 |
Increasing 3alpha,5alpha-THP following inhibition of neurosteroid biosynthesis in the ventral tegmental area reinstates anti-anxiety, social, and sexual behavior of naturally receptive rats.
Topics: Animals; Anxiety; Behavior, Animal; Exploratory Behavior; Female; Indoleacetic Acids; Indomethacin; | 2009 |
Pharmacological and pharmacokinetic characterization of the cannabinoid receptor 2 agonist, GW405833, utilizing rodent models of acute and chronic pain, anxiety, ataxia and catalepsy.
Topics: Amines; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anxiety; Ataxia; Behavior, Ani | 2005 |
Severe depersonalization and anxiety associated with indomethacin.
Topics: Anxiety; Depersonalization; Female; Gout; Humans; Indomethacin; Middle Aged | 1983 |
Progesterone withdrawal decreases latency to and increases duration of electrified prod burial: a possible rat model of PMS anxiety.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Diazepam; Disease Models, Animal; Electrosh | 1993 |
Involvement of pain associated anxiety in the development of morphine tolerance in formalin treated mice.
Topics: Animals; Anxiety; Aspirin; Diazepam; Drug Tolerance; Flumazenil; Formaldehyde; Indomethacin; Inflamm | 1994 |
Rat as model for studying behavior effects of hCG.
Topics: Animals; Anxiety; Behavior, Animal; Chorionic Gonadotropin; Electroencephalography; Electromyography | 2001 |
An overview of chronic recurring headache.
Topics: Acute Disease; Analgesics; Antidepressive Agents; Anxiety; Chronic Disease; Cortisone; Diuretics; Er | 1972 |
Management of rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Amitriptyline; Anxiety; Arthritis, Rheumatoid; Aspirin; Attitude of Health | 1969 |