Page last updated: 2024-10-29

indomethacin and Anorexia

indomethacin has been researched along with Anorexia in 7 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Anorexia: The lack or loss of APPETITE accompanied by an aversion to food and the inability to eat. It is the defining characteristic of the disorder ANOREXIA NERVOSA.

Research Excerpts

ExcerptRelevanceReference
" The anorexia of indomethacin-induced ulcerative ileitis was compared with that of the well-known anorexia of total parenteral nutrition (TPN)."7.69Mode of food intake reduction in Lewis rats with indomethacin-induced ulcerative ileitis. ( Holtzapple, PG; Levine, RA; Meguid, MM; Nandi, J; Oler, A; Opara, EI; Veerabagu, MP, 1996)
" Therefore, the purpose of the present study was to determine if administration of ibuprofen (ibu) or indomethacin (indo), which inhibit PG synthesis, would affect the food intake and body weight of tumor-bearing rats."3.70Inhibitors of prostaglandin synthesis do not improve food intake or body weight of tumor-bearing rats. ( McCarthy, DO, 1999)
" The anorexia of indomethacin-induced ulcerative ileitis was compared with that of the well-known anorexia of total parenteral nutrition (TPN)."3.69Mode of food intake reduction in Lewis rats with indomethacin-induced ulcerative ileitis. ( Holtzapple, PG; Levine, RA; Meguid, MM; Nandi, J; Oler, A; Opara, EI; Veerabagu, MP, 1996)
"Local inflammation was induced by subcutaneous injection of turpentine (100 microl/mouse)."1.30Dietary n-3 fatty acids differentially affect sickness behavior in mice during local and systemic inflammation. ( Conn, CA; Kluger, MJ; Kozak, W; Rudolph, K; Soszynski, D, 1997)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's3 (42.86)18.2507
2000's2 (28.57)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rorato, R1
Menezes, AM1
Giusti-Paiva, A1
de Castro, M1
Antunes-Rodrigues, J1
Elias, LL1
Yamamoto, K1
Asano, K1
Ito, Y1
Matsukawa, N1
Kim, S1
Yamatodani, A1
Naoi, K1
Kogure, S1
Saito, M1
Hamazaki, T1
Watanabe, S1
Veerabagu, MP1
Opara, EI1
Meguid, MM1
Nandi, J1
Oler, A1
Holtzapple, PG1
Levine, RA1
Kozak, W1
Soszynski, D1
Rudolph, K1
Conn, CA1
Kluger, MJ1
McCarthy, DO1
Langhans, W1
Harlacher, R1
Scharrer, E1

Other Studies

7 other studies available for indomethacin and Anorexia

ArticleYear
Prostaglandin mediates endotoxaemia-induced hypophagia by activation of pro-opiomelanocortin and corticotrophin-releasing factor neurons in rats.
    Experimental physiology, 2009, Volume: 94, Issue:3

    Topics: Adrenocorticotropic Hormone; alpha-MSH; Animals; Anorexia; Appetite Regulation; Corticosterone; Cort

2009
Involvement of hypothalamic cyclooxygenase-2, interleukin-1β and melanocortin in the development of docetaxel-induced anorexia in rats.
    Toxicology, 2012, Dec-16, Volume: 302, Issue:2-3

    Topics: Animals; Anorexia; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Docetaxel; Hypothalamus

2012
Differential effects of selective cyclooxygenase (COX)-1 and COX-2 inhibitors on anorexic response and prostaglandin generation in various tissues induced by zymosan.
    Biological & pharmaceutical bulletin, 2006, Volume: 29, Issue:7

    Topics: Animals; Anorexia; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 1; Cyclooxygenase 2; Cycl

2006
Mode of food intake reduction in Lewis rats with indomethacin-induced ulcerative ileitis.
    Physiology & behavior, 1996, Volume: 60, Issue:2

    Topics: Animals; Anorexia; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Cells, Cultured; Dinoprosto

1996
Dietary n-3 fatty acids differentially affect sickness behavior in mice during local and systemic inflammation.
    The American journal of physiology, 1997, Volume: 272, Issue:4 Pt 2

    Topics: Animals; Anorexia; Behavior, Animal; Body Temperature; Body Weight; Cachexia; Coconut Oil; Fatty Aci

1997
Inhibitors of prostaglandin synthesis do not improve food intake or body weight of tumor-bearing rats.
    Research in nursing & health, 1999, Volume: 22, Issue:5

    Topics: Analysis of Variance; Animals; Anorexia; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Cache

1999
Verapamil and indomethacin attenuate endotoxin-induced anorexia.
    Physiology & behavior, 1989, Volume: 46, Issue:3

    Topics: Animals; Anorexia; Dose-Response Relationship, Drug; Drug Interactions; Escherichia coli Infections;

1989