Page last updated: 2024-10-29

indomethacin and Ankylosis

indomethacin has been researched along with Ankylosis in 4 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Ankylosis: Fixation and immobility of a joint.

Research Excerpts

ExcerptRelevanceReference
"Indomethacin was administered for 6 weeks beginning at weaning to litters from heterozygote breeder pairs."5.28Transient inhibition of murine progressive ankylosis by indomethacin. ( Krug, HE; Mahowald, ML, 1991)
"Thirty-nine patients (46 elbows) with heterotopic ossification treated with excision were identified: 10 patients (16 elbows) had burns, 28 patients (29 elbows) had trauma, and one patient (one elbow) had a closed head injury."1.40Heterotopic ossification of the elbow treated with surgical resection: risk factors, bony ankylosis, and complications. ( Golz, A; Israel, H; Marra, G; Salazar, D, 2014)
"Heterotopic ossification is a frequent complication after spinal cord injury."1.39Ankylosing pelvitrochanteric heterotopic ossification in a patient with spinal cord injury. ( Gurcan, S; Kose, O; Ozyurek, S; Sehirlioglu, A, 2013)
"In an attempt to prevent postoperative recurrence of ossification, 100 mg of indomethacin was administered daily after surgery for 6 weeks."1.30Operative treatment of heterotopic hip ossification in patients with coma after brain injury. ( Caterini, R; Farsetti, P; Formisano, R; Ippolito, E; Penta, F, 1999)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's0 (0.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gurcan, S1
Ozyurek, S1
Kose, O1
Sehirlioglu, A1
Salazar, D1
Golz, A1
Israel, H1
Marra, G1
Ippolito, E1
Formisano, R1
Caterini, R1
Farsetti, P1
Penta, F1
Krug, HE1
Mahowald, ML1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Elbow Heterotopic Ossifications Associated With Radial Head Prosthesis: Risk and Prognostic Factors[NCT05547867]60 participants (Anticipated)Observational2022-09-12Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

4 other studies available for indomethacin and Ankylosis

ArticleYear
Ankylosing pelvitrochanteric heterotopic ossification in a patient with spinal cord injury.
    BMJ case reports, 2013, May-21, Volume: 2013

    Topics: Adult; Ankylosis; Anti-Inflammatory Agents, Non-Steroidal; Female; Hip Joint; Humans; Indomethacin;

2013
Heterotopic ossification of the elbow treated with surgical resection: risk factors, bony ankylosis, and complications.
    Clinical orthopaedics and related research, 2014, Volume: 472, Issue:7

    Topics: Adolescent; Adult; Aged; Ankylosis; Anti-Inflammatory Agents, Non-Steroidal; Biomechanical Phenomena

2014
Operative treatment of heterotopic hip ossification in patients with coma after brain injury.
    Clinical orthopaedics and related research, 1999, Issue:365

    Topics: Adolescent; Adult; Ankylosis; Anti-Inflammatory Agents, Non-Steroidal; Brain Injuries; Coma; Female;

1999
Transient inhibition of murine progressive ankylosis by indomethacin.
    Agents and actions, 1991, Volume: 34, Issue:1-2

    Topics: Animals; Ankylosis; Bone and Bones; Female; Indomethacin; Male; Mice; Mice, Inbred Strains

1991