Page last updated: 2024-10-29

indomethacin and Animal Mammary Carcinoma

indomethacin has been researched along with Animal Mammary Carcinoma in 9 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Research Excerpts

ExcerptRelevanceReference
"The effect of indomethacin on tumor-infiltrating lymphocytes (TIL) was investigated in a spontaneously developed and weakly immunogenic murine mammary adenocarcinoma (designated JC) in syngeneic immunocompetent BALB/c mice, a tumor model mimicking human disease."7.67Effect of indomethacin on tumor-infiltrating lymphocytes of a spontaneously developed murine mammary adenocarcinoma. ( Chao, TY; Chu, TM, 1989)
"The effect of indomethacin on tumor-infiltrating lymphocytes (TIL) was investigated in a spontaneously developed and weakly immunogenic murine mammary adenocarcinoma (designated JC) in syngeneic immunocompetent BALB/c mice, a tumor model mimicking human disease."3.67Effect of indomethacin on tumor-infiltrating lymphocytes of a spontaneously developed murine mammary adenocarcinoma. ( Chao, TY; Chu, TM, 1989)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's7 (77.78)18.2507
2000's1 (11.11)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Melamed, R1
Rosenne, E1
Shakhar, K1
Schwartz, Y1
Abudarham, N1
Ben-Eliyahu, S1
Kasayama, S1
Koga, M1
Kouhara, H1
Sumitani, S1
Wada, K1
Kishimoto, T1
Sato, B1
Lala, PK3
Parhar, RS1
Al-Mutter, N1
Orucevic, A1
Saarloos, MN1
Khoo, NK1
Yazici, Z2
Tavares, IA2
Soydan, AS1
Hollingsworth, SJ1
Bishai, PM2
Bennett, A2
Stamford, IF1
Fulton, AM1
Zhang, SZ1
Chong, YC1
Chao, TY1
Chu, TM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Impact of Perioperative Dexmedetomidine on Long-term Survival in Older Patients After Cancer Surgery: a Multicenter Randomized Trial[NCT06030804]4,532 participants (Anticipated)Interventional2023-09-12Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

9 other studies available for indomethacin and Animal Mammary Carcinoma

ArticleYear
Marginating pulmonary-NK activity and resistance to experimental tumor metastasis: suppression by surgery and the prophylactic use of a beta-adrenergic antagonist and a prostaglandin synthesis inhibitor.
    Brain, behavior, and immunity, 2005, Volume: 19, Issue:2

    Topics: Adenocarcinoma; Adrenergic beta-Antagonists; Animals; Cell Line, Tumor; Cyclooxygenase Inhibitors; D

2005
Unsaturated fatty acids are required for continuous proliferation of transformed androgen-dependent cells by fibroblast growth factor family proteins.
    Cancer research, 1994, Dec-15, Volume: 54, Issue:24

    Topics: Animals; Arachidonic Acids; Benzoquinones; Cell Adhesion; Cell Cycle; Cell Division; Culture Media,

1994
Eradication of spontaneous and experimental adenocarcinoma metastases with chronic indomethacin and intermittent IL-2 therapy.
    International journal of cancer, 1993, Jun-19, Volume: 54, Issue:4

    Topics: Adenocarcinoma; Animals; Drug Administration Schedule; Female; Immunity, Cellular; Indomethacin; Int

1993
Effects of chronic indomethacin therapy on the development and progression of spontaneous mammary tumors in C3H/HEJ mice.
    International journal of cancer, 1997, Nov-04, Volume: 73, Issue:3

    Topics: Age of Onset; Animals; Anticarcinogenic Agents; Female; Indomethacin; Lung Neoplasms; Mammary Neopla

1997
Effects of cancer immunotherapy with indomethacin and interleukin-2 on murine hemopoietic stem cells.
    Cancer research, 1992, Dec-01, Volume: 52, Issue:23

    Topics: Animals; Cell Count; Female; Hematopoietic Stem Cells; Immunotherapy; Indomethacin; Interleukin-2; K

1992
Methotrexate alters the fatty acid composition of NC adenocarcinoma cells in culture.
    European journal of cancer (Oxford, England : 1990), 1992, Volume: 28A, Issue:8-9

    Topics: Animals; Drug Synergism; Fatty Acids; Indomethacin; Mammary Neoplasms, Animal; Methotrexate; Mice; T

1992
Changes in tissue fatty acid composition in murine malignancy and following anticancer therapy.
    British journal of cancer, 1992, Volume: 65, Issue:2

    Topics: Animals; Drug Interactions; Fatty Acids; Female; Indomethacin; Liver; Mammary Glands, Animal; Mammar

1992
Role of the prostaglandin E2 receptor in mammary tumor metastasis.
    Cancer research, 1991, Apr-15, Volume: 51, Issue:8

    Topics: Animals; Cyclic AMP; Dinoprostone; Indomethacin; Mammary Neoplasms, Animal; Mice; Mice, Inbred BALB

1991
Effect of indomethacin on tumor-infiltrating lymphocytes of a spontaneously developed murine mammary adenocarcinoma.
    Cancer immunology, immunotherapy : CII, 1989, Volume: 30, Issue:3

    Topics: Adenocarcinoma; Animals; Cytotoxicity, Immunologic; Female; G(M1) Ganglioside; Glycosphingolipids; I

1989