Page last updated: 2024-10-29

indomethacin and Angor Pectoris

indomethacin has been researched along with Angor Pectoris in 16 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Research Excerpts

ExcerptRelevanceReference
"The influence of indomethacin therapy on the circulatory and antianginal effects of nitroglycerin were studied in six patients with stable angina pectoris."9.05Interaction of indomethacin and nitroglycerin on hemodynamics and exercise tolerance in patients with angina pectoris. ( Kellerman, D; Thadani, U, 1983)
" Although a 150 mg dose of aspirin reduced urinary dinor-TxB2 levels by over 75 per cent, it had no effect on the course of the chronic recurrent form of angina pectoris due to vasospasm ("vasotonic angina")."9.05Thromboxane A2 in vasotonic angina pectoris: evidence from direct measurements and inhibitor trials. ( FitzGerald, GA; Friesinger, GC; Maas, RL; Oates, JA; Roberts, LJ; Robertson, D; Robertson, RM, 1981)
"The influence of indomethacin therapy on the circulatory and antianginal effects of nitroglycerin were studied in six patients with stable angina pectoris."5.05Interaction of indomethacin and nitroglycerin on hemodynamics and exercise tolerance in patients with angina pectoris. ( Kellerman, D; Thadani, U, 1983)
" Although a 150 mg dose of aspirin reduced urinary dinor-TxB2 levels by over 75 per cent, it had no effect on the course of the chronic recurrent form of angina pectoris due to vasospasm ("vasotonic angina")."5.05Thromboxane A2 in vasotonic angina pectoris: evidence from direct measurements and inhibitor trials. ( FitzGerald, GA; Friesinger, GC; Maas, RL; Oates, JA; Roberts, LJ; Robertson, D; Robertson, RM, 1981)
" However, the gastroprotective effect of chronic stress was not manifested and there was no aggravation of indomethacin-induced gastric ulceration, either."3.79Does chronic stress enhance the risk of diseases? ( Filaretova, L; Laszlo, F; Morozova, O; Morschl, E; Zelena, D, 2013)
" Both patients exhibited anaphylactic manifestations, such as general rash and urticaria, along with angina pectoris with electrocardiographic ST-segment elevations after suppository administration of diclofenac sodium or indomethacin, the most commonly used NSAIDs."3.69Vasospastic angina induced by nonsteroidal anti-inflammatory drugs. ( Eguchi, H; Haramaki, N; Hashino, T; Ichiki, K; Ikeda, H; Imaizumi, T; Kai, H; Katoh, A; Mori, E; Ueno, T; Ueyama, T, 1997)
" This study describes the consequences of acute prostaglandin synthesis inhibition on the hemodynamic effects of nitroglycerin in patients with stable angina pectoris."3.67[Hemodynamic effects of nitroglycerin following acute inhibition of prostaglandin synthesis]. ( Punzengruber, C; Silberbauer, K; Sinzinger, H, 1986)
"A 23-year-old male with bronchial asthma developed eosinophilia (eosinophils greater than 2,000/mm3) and was observed at our hospital."1.28[Acute myocardial injury and repeated angina pectoris-like attacks in a young patient with Churg-Strauss syndrome]. ( Arai, Y; Fukushima, N; Isokane, N; Miyamoto, Y; Sano, Y; Suzuki, N, 1991)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199011 (68.75)18.7374
1990's2 (12.50)18.2507
2000's1 (6.25)29.6817
2010's2 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Filaretova, L1
Morozova, O1
Laszlo, F1
Morschl, E1
Zelena, D1
Mitchell, AJ1
Alexy, T1
Rubinsztain, L1
Iqbal, A1
Shah, AJ1
Zafari, AM1
Searles, CD1
Giffin, NJ1
McGregor, M1
Crelinsten, GL1
Thadani, U1
Kellerman, D1
Handin, RI1
Alexander, RW1
Robertson, RM1
Robertson, D1
Roberts, LJ1
Maas, RL1
FitzGerald, GA1
Friesinger, GC1
Oates, JA1
Mori, E1
Ikeda, H1
Ueno, T1
Kai, H1
Haramaki, N1
Hashino, T1
Ichiki, K1
Katoh, A1
Eguchi, H1
Ueyama, T1
Imaizumi, T1
Suzuki, N1
Arai, Y1
Miyamoto, Y1
Isokane, N1
Fukushima, N1
Sano, Y1
Punzengruber, C1
Silberbauer, K1
Sinzinger, H1
Sakai, K1
Yamazaki, T1
Nakamura, Y1
Sugimoto, T1
Pacold, I1
Hwang, MH1
Lawless, CE1
Diamond, P1
Scanlon, PJ1
Loeb, HS1
Weinberg, MS1
Quigg, RJ1
Salant, DJ1
Bernard, DB1
Sanz, ML1
Godfrey, C1
Golding, D1
Calabro, JJ1
Amante, CM1

Trials

3 trials available for indomethacin and Angor Pectoris

ArticleYear
Interaction of indomethacin and nitroglycerin on hemodynamics and exercise tolerance in patients with angina pectoris.
    Zeitschrift fur Kardiologie, 1983, Volume: 72 Suppl 3

    Topics: Aged; Angina Pectoris; Drug Interactions; Electrocardiography; Hemodynamics; Humans; Indomethacin; M

1983
Thromboxane A2 in vasotonic angina pectoris: evidence from direct measurements and inhibitor trials.
    The New England journal of medicine, 1981, Apr-23, Volume: 304, Issue:17

    Topics: Adult; Angina Pectoris; Angina Pectoris, Variant; Arteries; Aspirin; Clinical Trials as Topic; Coron

1981
Effects of indomethacin on coronary hemodynamics, myocardial metabolism and anginal threshold in coronary artery disease.
    The American journal of cardiology, 1986, Apr-15, Volume: 57, Issue:11

    Topics: Administration, Oral; Angina Pectoris; Animals; Cardiac Pacing, Artificial; Clinical Trials as Topic

1986

Other Studies

13 other studies available for indomethacin and Angor Pectoris

ArticleYear
Does chronic stress enhance the risk of diseases?
    Endocrine regulations, 2013, Volume: 47, Issue:4

    Topics: Adrenergic alpha-Antagonists; Angina Pectoris; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chr

2013
Rheumatoid Arthritis Presenting as Acute Myopericarditis.
    The American journal of medicine, 2016, Volume: 129, Issue:5

    Topics: Angina Pectoris; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Blood Sedimentation

2016
Paroxysmal hemicrania triggered by GTN.
    Cephalalgia : an international journal of headache, 2007, Volume: 27, Issue:8

    Topics: Aged; Angina Pectoris; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Hypertension; Indome

2007
Possible interactions of indomethacin and nitrates in angina pectoris.
    The American journal of cardiology, 1984, Jan-01, Volume: 53, Issue:1

    Topics: Aged; Angina Pectoris; Blood Pressure; Double-Blind Method; Drug Interactions; Drug Therapy, Combina

1984
Humoral heartache -- do platelets have a role?
    The New England journal of medicine, 1981, Apr-23, Volume: 304, Issue:17

    Topics: Angina Pectoris; Angina Pectoris, Variant; Animals; Aspirin; Blood Platelets; Coronary Circulation;

1981
Vasospastic angina induced by nonsteroidal anti-inflammatory drugs.
    Clinical cardiology, 1997, Volume: 20, Issue:7

    Topics: Aged; Angina Pectoris; Anti-Inflammatory Agents, Non-Steroidal; Coronary Angiography; Coronary Vasos

1997
[Acute myocardial injury and repeated angina pectoris-like attacks in a young patient with Churg-Strauss syndrome].
    Nihon Kyobu Shikkan Gakkai zasshi, 1991, Volume: 29, Issue:12

    Topics: Adult; Age Factors; Angina Pectoris; Aspirin; Asthma; Churg-Strauss Syndrome; Eosinophilia; Humans;

1991
[Hemodynamic effects of nitroglycerin following acute inhibition of prostaglandin synthesis].
    Zeitschrift fur Kardiologie, 1986, Volume: 75, Issue:11

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Angina Pectoris; Aspirin; Cyclooxygenase Inhibitors; Dinoprosto

1986
Protective effects of the antianginal agent nicorandil on arachidonate-induced sudden death in rats: comparison with several antianginal agents and cyclooxygenase inhibitors.
    Japanese journal of pharmacology, 1985, Volume: 37, Issue:1

    Topics: Angina Pectoris; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Cyclooxygenase Inhibitors; D

1985
Anuric renal failure precipitated by indomethacin and triamterene.
    Nephron, 1985, Volume: 40, Issue:2

    Topics: Acute Kidney Injury; Aged; Angina Pectoris; Anuria; Drug Interactions; Female; Humans; Indomethacin;

1985
Ischemic heart disease: part of the premenstrual syndrome?
    American heart journal, 1985, Volume: 110, Issue:3

    Topics: Adult; Angina Pectoris; Female; Humans; Indomethacin; Myocardial Infarction; Premenstrual Syndrome;

1985
Angina and indomethacin.
    British medical journal, 1970, Dec-05, Volume: 4, Issue:5735

    Topics: Adult; Aged; Angina Pectoris; Electrocardiography; Female; Humans; Indomethacin; Male; Middle Aged;

1970
Indomethacin in ankylosing spondylitis.
    Arthritis and rheumatism, 1968, Volume: 11, Issue:1

    Topics: Adult; Angina Pectoris; Aortic Valve Insufficiency; Female; Humans; Indomethacin; Iritis; Male; Midd

1968