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indomethacin and Angiogenesis, Pathologic

indomethacin has been researched along with Angiogenesis, Pathologic in 39 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Research Excerpts

ExcerptRelevanceReference
"Indomethacin delays healing of experimental gastric ulcers."7.69Influence of acid and angiogenesis on kinetics of gastric ulcer healing in rats: interaction with indomethacin. ( Flogerzi, B; Halter, F; Peskar, BM; Schmassmann, A; Tarnawski, A; Varga, L, 1995)
"Nitric oxide (NO) synthesized from L-arginine interacts with prostaglandins (PG) and sensory neuropeptides in the regulation of mucosal integrity, but the role of L-arginine, a substrate for NO-synthase, in gastroprotection and healing of chronic gastric ulcers has been little studied."7.69Role of L-arginine, a substrate for nitric oxide-synthase, in gastroprotection and ulcer healing. ( Brzozowski, T; Drozdowicz, D; Kedra, D; Konturek, SJ; Sliwowski, Z; Zaczek, M, 1997)
" Thus, our results show that polymeric nanocapsules are able to increase the intratumoral bioavailability of indomethacin and reduce the growth of implanted gliomas."5.35Indomethacin-loaded nanocapsules treatment reduces in vivo glioblastoma growth in a rat glioma model. ( Battastini, AM; Bernardi, A; Braganhol, E; Edelweiss, MI; Figueiró, F; Guterres, SS; Jäger, E; Pohlmann, AR, 2009)
"Dexamethasone and indomethacin each reduced pain behavior, synovial inflammation, and synovial angiogenesis 35 days after meniscal transection."3.77Contributions of angiogenesis to inflammation, joint damage, and pain in a rat model of osteoarthritis. ( Ashraf, S; Mapp, PI; Walsh, DA, 2011)
" Here we characterized the effects of non-selective (indomethacin) and selective (NS398, celecoxib) cyclooxygenase inhibitors on parameters of angiogenesis in human pancreatic adenocarcinoma cells."3.72Celecoxib inhibits angiogenesis by inducing endothelial cell apoptosis in human pancreatic tumor xenografts. ( Davis, DW; Ellis, LM; Khanbolooki, S; Lashinger, LM; McConkey, DJ; Nawrocki, S; Raut, CP; Xiong, H, 2004)
"Indomethacin delays healing of experimental gastric ulcers."3.69Influence of acid and angiogenesis on kinetics of gastric ulcer healing in rats: interaction with indomethacin. ( Flogerzi, B; Halter, F; Peskar, BM; Schmassmann, A; Tarnawski, A; Varga, L, 1995)
"Nitric oxide (NO) synthesized from L-arginine interacts with prostaglandins (PG) and sensory neuropeptides in the regulation of mucosal integrity, but the role of L-arginine, a substrate for NO-synthase, in gastroprotection and healing of chronic gastric ulcers has been little studied."3.69Role of L-arginine, a substrate for nitric oxide-synthase, in gastroprotection and ulcer healing. ( Brzozowski, T; Drozdowicz, D; Kedra, D; Konturek, SJ; Sliwowski, Z; Zaczek, M, 1997)
"Indomethacine, protamine-sulphate and hydrocortisone were found to decrease the activity of metastatic processes of Lewis carcinoma after the removal of the primary tumour."3.67[Effect of actions inhibiting neovascularization of the metastasis of Lewis lung carcinoma]. ( Balitskiĭ, KP; Lisniak, IA; Sopotsinskaia, EB, 1985)
"Low doses of indomethacin were applied topically to rabbit eyes in an experimental model of immunologically provoked inflammatory keratitis."3.66Inhibitors of prostaglandin synthesis and the cornea. ( Barthen, ER; Oosterhuis, JA; van Delft, JL; van Haeringen, NJ, 1983)
"The growth rate (studied by mean tumor dry weight) and vascularization (studied by microangiography) of two transplantable rat tumors, a 20-methylcholanthrene-induced fibrosarcoma and a hepatoma, were significantly reduced by three prostaglandin synthesis inhibitors, indomethacin, diclofenac-sodium and aspirin, irrespective of whether the drugs were administered early or late during tumor growth."3.66Effects of prostaglandin synthesis inhibitors on tumor growth and vascularization. Experimental studies in the rat. ( Peterson, HI, 1983)
"Compared with controls (R1, and anticancer drug SN-38), TA displayed prolonged tumor retention and enhanced therapeutic efficacy in xenograft mouse models at a reduced dosage."1.48COX-2 Inhibition mediated anti-angiogenic activatable prodrug potentiates cancer therapy in preclinical models. ( Han, J; Kim, HS; Kim, JS; Ren, WX; Sharma, A, 2018)
" Thus, our results show that polymeric nanocapsules are able to increase the intratumoral bioavailability of indomethacin and reduce the growth of implanted gliomas."1.35Indomethacin-loaded nanocapsules treatment reduces in vivo glioblastoma growth in a rat glioma model. ( Battastini, AM; Bernardi, A; Braganhol, E; Edelweiss, MI; Figueiró, F; Guterres, SS; Jäger, E; Pohlmann, AR, 2009)
"Indomethacin can inhibit the growth of transplanted human colorectal HCT116 tumor in association with a significant reduction in angiogenesis, which may be achieved through inhibition of VEGF."1.32Experimental study of the inhibitory effect of indomethacin on the growth and angiogenesis of human colon cancer xenografts. ( Wang, HM; Zhang, GY, 2004)
"The histamine-induced increase in the content of VEGF protein in the conditioned medium was inhibited by the cyclic AMP antagonist Rp-cAMP (IC(50) 6."1.31Enhancement by histamine of vascular endothelial growth factor production in granulation tissue via H(2) receptors. ( Ghosh, AK; Hirasawa, N; Ohuchi, K, 2001)
"However, NSAIDs produce gastroduodenal ulcers in about 25% of users (often with bleeding and/or perforations) and delay ulcer healing, presumably by blocking prostaglandin synthesis from cyclooxygenase (COX)-1 and COX-2 (ref."1.30Inhibition of angiogenesis by nonsteroidal anti-inflammatory drugs: insight into mechanisms and implications for cancer growth and ulcer healing. ( Itani, RM; Jones, MK; Levin, E; Peskar, BM; Sarfeh, IJ; Tarnawski, AS; Wang, H, 1999)
"In indomethacin-treated rabbits, however, ceruloplasmin at the same high doses failed to induce angiogenesis."1.26Role of prostaglandin E1 and copper in angiogenesis. ( Gullino, PM; Jones, J; Ziche, M, 1982)

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-199014 (35.90)18.7374
1990's8 (20.51)18.2507
2000's13 (33.33)29.6817
2010's4 (10.26)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wu, L1
Wang, W2
Dai, M1
Li, H1
Chen, C1
Wang, D1
Kim, HS1
Sharma, A1
Ren, WX1
Han, J1
Kim, JS1
Bernardi, A1
Braganhol, E1
Jäger, E1
Figueiró, F1
Edelweiss, MI1
Pohlmann, AR1
Guterres, SS1
Battastini, AM1
Ashraf, S1
Mapp, PI1
Walsh, DA1
Silver, K1
Desormaux, A1
Freeman, LC1
Lillich, JD1
Bustuoabad, OD1
di Gianni, PD1
Franco, M1
Kordon, EC1
Vanzulli, SI1
Meiss, RP1
Grion, LC1
Díaz, GS1
Nosetto, SH1
Hockl, P1
Lombardi, MG1
Pasqualini, CD1
Ruggiero, RA1
Tanaka, K1
Watanabe, M1
Kuraishi, Y1
Kimura, I1
Suzuki, T1
Kiniwa, M1
Wang, HM1
Zhang, GY1
Fukada, SY1
Iyomasa, MM1
Cunha, FQ1
Corrêa, FM1
de Oliveira, AM1
Raut, CP1
Nawrocki, S1
Lashinger, LM1
Davis, DW1
Khanbolooki, S1
Xiong, H1
Ellis, LM1
McConkey, DJ1
Axelsson, H1
Lönnroth, C1
Svanberg, E1
Lundholm, K1
Singh, SK1
Bhusari, S1
Singh, R1
Saxena, A1
Mondhe, D1
Qazi, GN1
Sundbeck, A1
Karlsson, L1
Lilja, J1
Peterson, HI2
Ziche, M1
Jones, J1
Gullino, PM1
Rochels, R1
Schmitt, EJ1
Busse, WD1
Reim, M1
von Kiether, R1
Oglodek, C1
Schaffelt, F1
Thüne, G1
Harvey, PT1
Cherry, PM1
van Haeringen, NJ1
Oosterhuis, JA1
van Delft, JL1
Barthen, ER1
Frucht, J1
Zauberman, H1
Konturek, SJ2
Brzozowski, T2
Majka, I1
Pawlik, W1
Stachura, J1
Schmassmann, A1
Tarnawski, A1
Peskar, BM2
Varga, L1
Flogerzi, B1
Halter, F1
Colville-Nash, PR1
Alam, CA1
Appleton, I1
Brown, JR1
Seed, MP1
Willoughby, DA1
Fan, TP1
Hu, DE1
Guard, S1
Gresham, GA1
Watling, KJ1
Sliwowski, Z1
Drozdowicz, D1
Zaczek, M1
Kedra, D1
Jones, MK2
Wang, H1
Levin, E1
Itani, RM1
Sarfeh, IJ1
Tarnawski, AS2
Sawaoka, H1
Tsuji, S1
Tsujii, M1
Gunawan, ES1
Sasaki, Y1
Kawano, S1
Hori, M1
Gołab, J1
Kozar, K1
Kamiński, R1
Czajka, A1
Marczak, M1
Switaj, T1
Giermasz, A1
Stokłosa, T1
Lasek, W1
Zagozdzon, R1
Mucha, K1
Jakóbisiak, M1
Rozic, JG1
Chakraborty, C1
Lala, PK1
Ghosh, AK1
Hirasawa, N1
Ohuchi, K1
Szabó, IL1
Kawanaka, H1
Husain, SS1
Connolly, EM1
Harmey, JH1
O'Grady, T1
Foley, D1
Roche-Nagle, G1
Kay, E1
Bouchier-Hayes, DJ1
Spisni, E1
Manica, F1
Tomasi, V1
Sopotsinskaia, EB1
Lisniak, IA1
Balitskiĭ, KP1
Amemiya, K1
Suzuki, J1
Kimura, M1
Silverman, KJ1
Lund, DP1
Zetter, BR1
Lainey, LL1
Shahood, JA1
Freiman, DG1
Folkman, J1
Barger, AC1
Ohtsu, A1
Fujii, K1
Kurozumi, S1
Robin, JB1
Regis-Pacheco, LF1
Kash, RL1
Schanzlin, DJ1
Davel, LE1
Miguez, MM1
de Lustig, ES1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluation of Topical Application of 5% Imiquimod, 0.05% Imiquimod and 0.05% Nanoencapsulated Imiquimod Gel in the Treatment of Actinic Cheilitis: a Randomized Controlled Trial[NCT04219358]Phase 149 participants (Actual)Interventional2019-03-23Terminated (stopped due to Study terminated because of COVID19 pandemics.)
Radiosensitization With a COX-2 Inhibitor (Celecoxib), With Chemoradiation for Cancer of the Head and Neck[NCT00581971]Phase 1/Phase 230 participants (Actual)Interventional2002-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Response as Evaluated by Recurrence of Diseases

Evaluate the response to concurrent celecoxib, carboplatin, paclitaxel, and radiotherapy in the treatment of locally advanced SSC of the head and neck. Response is determined by local control only, local and distant metastasis, distant metastasis only, second primary, and surgical salvage. (NCT00581971)
Timeframe: 2 years from end of treatment (Radiation therapy)

InterventionParticipants (Number)
Local Control OnlyLocal Control and Distant MetastasisDistant Metastatsis OnlySecondary Primary - Site UnknownSurgical Salvage
Recurrence62123

Toxicity of Celecoxib With Concurrent Weekly Chemotherapy and Radiotherapy in the Treatment of Locally Advanced or Recurrent Squamous Cell Carcinoma of the Head and Neck.

Particpants experiencing Acute Toxicities > Grade 3 (NCT00581971)
Timeframe: 2 years from radiation therapy

Interventionparticipants (Number)
HematologicDermatitisMucositis/Dysphagia
Acute Toxicity12716

Other Studies

39 other studies available for indomethacin and Angiogenesis, Pathologic

ArticleYear
PPARα ligand, AVE8134, and cyclooxygenase inhibitor therapy synergistically suppress lung cancer growth and metastasis.
    BMC cancer, 2019, Dec-02, Volume: 19, Issue:1

    Topics: Animals; Antineoplastic Agents; Benzoates; Bezafibrate; Cell Line, Tumor; Cell Movement; Cell Prolif

2019
COX-2 Inhibition mediated anti-angiogenic activatable prodrug potentiates cancer therapy in preclinical models.
    Biomaterials, 2018, Volume: 185

    Topics: A549 Cells; Angiogenesis Inhibitors; Animals; Cell Line, Tumor; Cyclooxygenase 2; Cyclooxygenase 2 I

2018
Indomethacin-loaded nanocapsules treatment reduces in vivo glioblastoma growth in a rat glioma model.
    Cancer letters, 2009, Aug-18, Volume: 281, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Body Weight; Cell Division; Cell

2009
Contributions of angiogenesis to inflammation, joint damage, and pain in a rat model of osteoarthritis.
    Arthritis and rheumatism, 2011, Volume: 63, Issue:9

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Cartilage, Articular; Dexamethas

2011
Expression of pleiotrophin, an important regulator of cell migration, is inhibited in intestinal epithelial cells by treatment with non-steroidal anti-inflammatory drugs.
    Growth factors (Chur, Switzerland), 2012, Volume: 30, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bone and Bones; Carrier Proteins; Cell Line; Cell

2012
Embryonal mass and hormone-associated effects of pregnancy inducing a differential growth of four murine tumors.
    Oncology research, 2002, Volume: 13, Issue:3

    Topics: Adenocarcinoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Division; Estrogens; Female;

2002
Peroral TAS-202 reduced vessel density in rats with adjuvant-induced arthritis.
    European journal of pharmacology, 2003, Apr-11, Volume: 466, Issue:1-2

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Blood Vessels; Dep

2003
Experimental study of the inhibitory effect of indomethacin on the growth and angiogenesis of human colon cancer xenografts.
    Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA, 2004, Volume: 24, Issue:2

    Topics: Animals; Colonic Neoplasms; Cyclooxygenase 2; Humans; Indomethacin; Isoenzymes; Membrane Proteins; M

2004
Mechanisms of impaired vascular response to ANG II in perivascular injured carotid arteries of ovariectomized rat.
    Journal of cardiovascular pharmacology, 2004, Volume: 44, Issue:3

    Topics: Angiotensin II; Animals; Calcium; Carotid Artery Injuries; Dose-Response Relationship, Drug; Endothe

2004
Celecoxib inhibits angiogenesis by inducing endothelial cell apoptosis in human pancreatic tumor xenografts.
    Cancer biology & therapy, 2004, Volume: 3, Issue:12

    Topics: Adenocarcinoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Celecoxib; Cyclooxygena

2004
Cyclooxygenase inhibition in early onset of tumor growth and related angiogenesis evaluated in EP1 and EP3 knockout tumor-bearing mice.
    Angiogenesis, 2005, Volume: 8, Issue:4

    Topics: Animals; Cell Line, Tumor; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Indomethac

2005
Effect of acetyl 11-keto beta-boswellic acid on metastatic growth factor responsible for angiogenesis.
    Vascular pharmacology, 2007, Volume: 46, Issue:5

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Alkylating; Collagen; Cyclooxygenase Inhibi

2007
Inhibition of tumour vascularization by tranexamic acid. Experimental studies on possible mechanisms.
    Anticancer research, 1981, Volume: 1, Issue:5

    Topics: Angiography; Animals; Cyclohexanecarboxylic Acids; Indomethacin; Microscopy, Electron; Muscles; Neop

1981
Role of prostaglandin E1 and copper in angiogenesis.
    Journal of the National Cancer Institute, 1982, Volume: 69, Issue:2

    Topics: Alprostadil; Animals; Carcinoma 256, Walker; Ceruloplasmin; Copper; Cornea; Dinoprost; Dinoprostone;

1982
[Experimental inhibition of corneal neovascularization following keratoplasty].
    Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 1982, Volume: 79, Issue:2

    Topics: Animals; Cornea; Corneal Transplantation; Indomethacin; Neovascularization, Pathologic; Rabbits

1982
[Effect of inhibitors of prostaglandin synthesis on the eye].
    Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 1983, Volume: 80, Issue:2

    Topics: Animals; Burns, Chemical; Diclofenac; Eye; Eye Burns; Eye Diseases; Humans; Indomethacin; Inflammati

1983
Indomethacin v. dexamethasone in the suppression of corneal neovascularization.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 1983, Volume: 18, Issue:6

    Topics: Animals; Cornea; Corneal Diseases; Dexamethasone; Indomethacin; Neovascularization, Pathologic; Rabb

1983
Inhibitors of prostaglandin synthesis and the cornea.
    Documenta ophthalmologica. Advances in ophthalmology, 1983, Dec-15, Volume: 56, Issue:1-2

    Topics: Animals; Cornea; Indomethacin; Keratitis; Neovascularization, Pathologic; Prostaglandin Antagonists;

1983
Effects of prostaglandin synthesis inhibitors on tumor growth and vascularization. Experimental studies in the rat.
    Invasion & metastasis, 1983, Volume: 3, Issue:3

    Topics: Animals; Aspirin; Diclofenac; Fibrosarcoma; Indomethacin; Liver Neoplasms, Experimental; Neoplasm Tr

1983
Topical indomethacin effect on neovascularisation of the cornea and on prostaglandin E2 levels.
    The British journal of ophthalmology, 1984, Volume: 68, Issue:9

    Topics: Administration, Topical; Animals; Cornea; Dinoprostone; Indomethacin; Keratitis; Neovascularization,

1984
Omentum and basic fibroblast growth factor in healing of chronic gastric ulcerations in rats.
    Digestive diseases and sciences, 1994, Volume: 39, Issue:5

    Topics: Animals; Blood Flow Velocity; Chronic Disease; Dinoprostone; Eflornithine; Fibroblast Growth Factor

1994
Influence of acid and angiogenesis on kinetics of gastric ulcer healing in rats: interaction with indomethacin.
    The American journal of physiology, 1995, Volume: 268, Issue:2 Pt 1

    Topics: Animals; Bromodeoxyuridine; Drug Combinations; Female; Fibroblast Growth Factor 2; Gastric Acid; Gas

1995
The pharmacological modulation of angiogenesis in chronic granulomatous inflammation.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 274, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Cortisone; Dexamethasone

1995
Stimulation of angiogenesis by substance P and interleukin-1 in the rat and its inhibition by NK1 or interleukin-1 receptor antagonists.
    British journal of pharmacology, 1993, Volume: 110, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists

1993
Role of L-arginine, a substrate for nitric oxide-synthase, in gastroprotection and ulcer healing.
    Journal of gastroenterology, 1997, Volume: 32, Issue:4

    Topics: Animals; Arginine; Capsaicin; Citrulline; Dose-Response Relationship, Drug; Endothelium; Gastric Aci

1997
Inhibition of angiogenesis by nonsteroidal anti-inflammatory drugs: insight into mechanisms and implications for cancer growth and ulcer healing.
    Nature medicine, 1999, Volume: 5, Issue:12

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase

1999
Cyclooxygenase inhibitors suppress angiogenesis and reduce tumor growth in vivo.
    Laboratory investigation; a journal of technical methods and pathology, 1999, Volume: 79, Issue:12

    Topics: Animals; Apoptosis; Cell Division; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors;

1999
Interleukin 12 and indomethacin exert a synergistic, angiogenesis-dependent antitumor activity in mice.
    Life sciences, 2000, Feb-18, Volume: 66, Issue:13

    Topics: Animals; Antineoplastic Agents; Cyclooxygenase Inhibitors; Drug Synergism; Drug Therapy, Combination

2000
Cyclooxygenase inhibitors retard murine mammary tumor progression by reducing tumor cell migration, invasiveness and angiogenesis.
    International journal of cancer, 2001, Aug-15, Volume: 93, Issue:4

    Topics: Animals; Cell Division; Cell Movement; Cell Survival; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxyge

2001
Enhancement by histamine of vascular endothelial growth factor production in granulation tissue via H(2) receptors.
    British journal of pharmacology, 2001, Volume: 134, Issue:7

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cells, Cultured; Cimetidine; Cyclic A

2001
von Hippel Lindau tumor suppressor and HIF-1alpha: new targets of NSAIDs inhibition of hypoxia-induced angiogenesis.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2002, Volume: 16, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Hypoxia; Cell Line; Endothelial Growth Factor

2002
Cyclo-oxygenase inhibition reduces tumour growth and metastasis in an orthotopic model of breast cancer.
    British journal of cancer, 2002, Jul-15, Volume: 87, Issue:2

    Topics: Adenocarcinoma; Angiogenesis Inhibitors; Animals; Apoptosis; Cyclooxygenase 1; Cyclooxygenase 2; Cyc

2002
Involvement of prostanoids in the regulation of angiogenesis by polypeptide growth factors.
    Prostaglandins, leukotrienes, and essential fatty acids, 1992, Volume: 47, Issue:2

    Topics: Allantois; Alprostadil; Animals; Chick Embryo; Chorion; Enzyme Induction; Fibroblast Growth Factors;

1992
[Effect of actions inhibiting neovascularization of the metastasis of Lewis lung carcinoma].
    Eksperimental'naia onkologiia, 1985, Volume: 7, Issue:5

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Drug Evaluation, Preclinical; Hy

1985
[Mechanism of action of pronase on chronic proliferative inflammation including granuloma angiogenesis in mice].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1986, Volume: 88, Issue:4

    Topics: Animals; Collagen; Diabetes Mellitus, Experimental; Granuloma; Hydrocortisone; Hydroxyproline; Indom

1986
Angiogenic activity of adipose tissue.
    Biochemical and biophysical research communications, 1988, May-31, Volume: 153, Issue:1

    Topics: Adipose Tissue; Animals; Cornea; Coronary Disease; Indomethacin; Neovascularization, Pathologic; Pro

1988
Induction of angiogenic response by chemically stable prostacyclin analogs.
    Prostaglandins, leukotrienes, and essential fatty acids, 1988, Volume: 33, Issue:1

    Topics: Allantois; Animals; Biological Assay; Chick Embryo; Chorion; Dexamethasone; Epoprostenol; Indomethac

1988
The histopathology of corneal neovascularization. Inhibitor effects.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1985, Volume: 103, Issue:2

    Topics: Animals; Chemotaxis, Leukocyte; Cornea; Corneal Injuries; Disease Models, Animal; Electrocoagulation

1985
Evidence that indomethacin inhibits lymphocyte-induced angiogenesis.
    Transplantation, 1985, Volume: 39, Issue:5

    Topics: Angiogenesis Inducing Agents; Animals; Female; Indomethacin; Lymphocytes; Mammary Neoplasms, Experim

1985