Page last updated: 2024-10-29

indomethacin and Anemia

indomethacin has been researched along with Anemia in 19 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Anemia: A reduction in the number of circulating ERYTHROCYTES or in the quantity of HEMOGLOBIN.

Research Excerpts

ExcerptRelevanceReference
"Dyspeptic symptoms, gastrointestinal bleeding, or the development of anaemia without dyspepsia in patients treated with indomethacin may be manifestations of peptic ulceration."7.64Gastric ulceration occurring during indomethacin therapy. ( Hart, FD; Huskisson, EC; Taylor, RT; Trapnell, DH; Whitehouse, GH, 1968)
"NO-indomethacin was dissolved in dimethyl formamide followed by i."5.42Nitric oxide-releasing indomethacin enhances susceptibility to Trypanosoma cruzi infection acting in the cell invasion and oxidative stress associated with anemia. ( Cecchini, R; da Silva, RV; Malvezi, AD; Martins, MI; Martins-Pinge, MC; Panis, C; Pinge-Filho, P; Rizzo, LV; Tatakihara, VL; Yamada-Ogatta, SF; Yamauchi, LM; Zanluqui, NG, 2015)
" One hundred eight cancer patients who experienced progressive cachexia due to solid, mainly gastrointestinal tumors were randomized to receive twice daily a cyclo-oxygenase inhibitor (controls; indomethacin, 50 mg twice a day) or indomethacin and erythropoietin, provided on individual basis to prevent development of progressive anemia (study patients; indomethacin, 50 mg twice a day plus rhEPO; range, 12,000-30,000 units per week)."5.08Protection of metabolic and exercise capacity in unselected weight-losing cancer patients following treatment with recombinant erythropoietin: a randomized prospective study. ( Bosaeus, I; Brevinge, H; Daneryd, P; Körner, U; Lindholm, E; Lundholm, K; Pettersson, C; Sandström, R; Svanberg, E, 1998)
"Dyspeptic symptoms, gastrointestinal bleeding, or the development of anaemia without dyspepsia in patients treated with indomethacin may be manifestations of peptic ulceration."3.64Gastric ulceration occurring during indomethacin therapy. ( Hart, FD; Huskisson, EC; Taylor, RT; Trapnell, DH; Whitehouse, GH, 1968)
"NO-indomethacin was dissolved in dimethyl formamide followed by i."1.42Nitric oxide-releasing indomethacin enhances susceptibility to Trypanosoma cruzi infection acting in the cell invasion and oxidative stress associated with anemia. ( Cecchini, R; da Silva, RV; Malvezi, AD; Martins, MI; Martins-Pinge, MC; Panis, C; Pinge-Filho, P; Rizzo, LV; Tatakihara, VL; Yamada-Ogatta, SF; Yamauchi, LM; Zanluqui, NG, 2015)
" The dose-response to vasoconstrictors and vasodilators was assessed in small resistance coronary arteries."1.35Effect of fetal anaemia on myocardial ischaemia-reperfusion injury and coronary vasoreactivity in adult sheep. ( Davis, LE; Giraud, GD; He, GW; Hohimer, AR; Underwood, MJ; Van Winkle, DM; Yang, Q, 2008)
"Another therapy involves the treatment for premature labor, which is the most common cause of pregnancy loss in dialysis patients."1.29Pregnancy in women with end-stage renal disease: treatment of anemia and premature labor. ( Ambrose, S; Hou, S; Hussey, M; Orlowski, J; Pahl, M; Wong, D, 1993)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19909 (47.37)18.7374
1990's4 (21.05)18.2507
2000's2 (10.53)29.6817
2010's2 (10.53)24.3611
2020's2 (10.53)2.80

Authors

AuthorsStudies
Marini, D1
Xu, J1
Sun, L1
Jaeggi, E1
Seed, M1
Gephart, SM1
Underwood, MA1
Rosito, S1
Kim, JH1
Caplan, MS1
Yamamoto, A1
Itoh, T1
Nasu, R1
Nishida, R1
Tatakihara, VL1
Malvezi, AD1
Panis, C1
Cecchini, R1
Zanluqui, NG1
Yamauchi, LM1
Martins, MI1
da Silva, RV1
Yamada-Ogatta, SF1
Rizzo, LV1
Martins-Pinge, MC1
Pinge-Filho, P1
Yang, Q1
Hohimer, AR1
Giraud, GD1
Van Winkle, DM1
Underwood, MJ1
He, GW1
Davis, LE1
Kelsey, WM1
Scharyj, M1
Sawamura, M1
Yamaguchi, S1
Murakami, H1
Kitahara, T1
Itoh, K1
Maehara, T1
Kawada, E1
Matsushima, T1
Tamura, J1
Naruse, T1
Hou, S1
Orlowski, J1
Pahl, M1
Ambrose, S1
Hussey, M1
Wong, D1
Schiffl, H1
Lang, SM1
Daneryd, P2
Svanberg, E1
Körner, U1
Lindholm, E1
Sandström, R1
Brevinge, H1
Pettersson, C1
Bosaeus, I1
Lundholm, K1
Taniguchi, S1
Shibuya, T1
Harada, M1
Niho, Y1
Flynn, JT1
Datta, MC1
Spears, HJ1
Dowla, HA1
Smyth, CJ1
Gaetani, M1
Debeus, R1
Vidi, A1
Coppi, G1
Julou, L1
Ducrot, R1
Fournel, J1
Ganter, P1
Populaire, P1
Durel, J1
Myon, J1
Pascal, S1
Pasquet, J1
Jacobsen, CD1
Taylor, RT1
Huskisson, EC1
Whitehouse, GH1
Hart, FD1
Trapnell, DH1

Reviews

4 reviews available for indomethacin and Anemia

ArticleYear
Current and future role of fetal cardiovascular MRI in the setting of fetal cardiac interventions.
    Prenatal diagnosis, 2020, Volume: 40, Issue:1

    Topics: Anemia; Anti-Inflammatory Agents, Non-Steroidal; Atrial Septum; Blood Transfusion, Intrauterine; Duc

2020
Grading the evidence to identify strategies to modify risk for necrotizing enterocolitis.
    Pediatric research, 2020, Volume: 88, Issue:Suppl 1

    Topics: Adrenal Cortex Hormones; Anemia; Anti-Bacterial Agents; Ductus Arteriosus, Patent; Enterocolitis, Ne

2020
Retrolental fibroplasia: update.
    Transactions of the New Orleans Academy of Ophthalmology, 1986, Volume: 34

    Topics: Anemia; Blood Vessels; Carbon Dioxide; Humans; Indomethacin; Infant, Newborn; Infant, Premature; Mal

1986
Optimum therapeutic program in seropositive nodular rheumatoid arthritis.
    The Medical clinics of North America, 1968, Volume: 52, Issue:3

    Topics: Adaptation, Psychological; Analgesics; Anemia; Anti-Inflammatory Agents; Antimalarials; Arthritis, R

1968

Trials

2 trials available for indomethacin and Anemia

ArticleYear
Protection of metabolic and exercise capacity in unselected weight-losing cancer patients following treatment with recombinant erythropoietin: a randomized prospective study.
    Cancer research, 1998, Dec-01, Volume: 58, Issue:23

    Topics: Aged; Anemia; Anti-Inflammatory Agents, Non-Steroidal; Cachexia; Cyclooxygenase Inhibitors; Energy M

1998
Epoetin alfa for protection of metabolic and exercise capacity in cancer patients.
    Seminars in oncology, 2002, Volume: 29, Issue:3 Suppl 8

    Topics: Aged; Anemia; Anti-Inflammatory Agents, Non-Steroidal; Cachexia; Cyclooxygenase Inhibitors; Energy M

2002

Other Studies

13 other studies available for indomethacin and Anemia

ArticleYear
Sodium alginate ameliorates indomethacin-induced gastrointestinal mucosal injury via inhibiting translocation in rats.
    World journal of gastroenterology, 2014, Mar-14, Volume: 20, Issue:10

    Topics: Alginates; Anemia; Animals; Anti-Ulcer Agents; Atrophy; Bacterial Translocation; Biomarkers; Capilla

2014
Nitric oxide-releasing indomethacin enhances susceptibility to Trypanosoma cruzi infection acting in the cell invasion and oxidative stress associated with anemia.
    Chemico-biological interactions, 2015, Feb-05, Volume: 227

    Topics: Anemia; Animals; Cells, Cultured; Disease Susceptibility; Erythrocytes; Female; Indomethacin; Macrop

2015
Effect of fetal anaemia on myocardial ischaemia-reperfusion injury and coronary vasoreactivity in adult sheep.
    Acta physiologica (Oxford, England), 2008, Volume: 194, Issue:4

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Anemia; Animals; Cardiovascular

2008
Fatal hepatitis probably due to indomethacin.
    JAMA, 1967, Feb-20, Volume: 199, Issue:8

    Topics: Anemia; Chemical and Drug Induced Liver Injury; Child; Humans; Indomethacin; Male

1967
Cyclic haemopoiesis at 7- or 8-day intervals.
    British journal of haematology, 1994, Volume: 88, Issue:1

    Topics: Adult; Anemia; C-Reactive Protein; Erythropoietin; Female; Fever; Granulocyte Colony-Stimulating Fac

1994
Pregnancy in women with end-stage renal disease: treatment of anemia and premature labor.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1993, Volume: 21, Issue:1

    Topics: Abnormalities, Drug-Induced; Adult; Anemia; Erythropoietin; Female; Hematocrit; Humans; Hypertension

1993
Hypertension induced by recombinant human erythropoietin (rHU-EPO) can be prevented by indomethacin. Pathogenetic role of cytosolic calcium.
    European journal of medical research, 1997, Mar-24, Volume: 2, Issue:3

    Topics: Anemia; Anti-Inflammatory Agents, Non-Steroidal; Blood Platelets; Calcium; Cytosol; Erythropoietin;

1997
Prostaglandin-mediated suppression of in vitro growth of erythroid progenitor cells.
    Kidney international, 1989, Volume: 36, Issue:4

    Topics: Anemia; Cell Division; Erythroid Precursor Cells; Erythropoietin; Humans; In Vitro Techniques; Indom

1989
Relationship between plasma PGE2 level and changes in hemoglobin proportions during bleeding-induced anemia in adult rats.
    Biochemical and biophysical research communications, 1987, Dec-31, Volume: 149, Issue:3

    Topics: Anemia; Animals; Aspirin; Dinoprostone; Erythropoiesis; Gene Expression Regulation; Hemoglobins; Hem

1987
Toxicological investigations of 4-prenyl-1,2-diphenyl-3,5-pyrazolidinedione (DA 2370). 3. A comparative study of short-term toxicity of DA 2370 and other non-steroid anti-inflammatory drugs (phenylbutazone, mefenamic acid, indometacin and benzydamine) in
    Arzneimittel-Forschung, 1972, Volume: 22, Issue:1

    Topics: Administration, Oral; Aminohippuric Acids; Anemia; Animals; Anti-Inflammatory Agents; Benzyl Compoun

1972
[Toxicologic study of methiazinic acid (16091 R.P)].
    Arzneimittel-Forschung, 1969, Volume: 19, Issue:8

    Topics: Abnormalities, Drug-Induced; Acetates; Anemia; Animals; Dogs; Drug Tolerance; Female; Gastric Mucosa

1969
[Drug-induced anemias].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1970, Dec-15, Volume: 90, Issue:24

    Topics: Adrenal Cortex Hormones; Anemia; Barbiturates; Bone Marrow; Chloramphenicol; Chlorpromazine; Dihydro

1970
Gastric ulceration occurring during indomethacin therapy.
    British medical journal, 1968, Dec-21, Volume: 4, Issue:5633

    Topics: Adult; Aged; Anemia; Dyspepsia; Female; Humans; Indomethacin; Male; Middle Aged; Pylorus; Radiograph

1968