indomethacin has been researched along with Amyloidosis in 9 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Amyloidosis: A group of sporadic, familial and/or inherited, degenerative, and infectious disease processes, linked by the common theme of abnormal protein folding and deposition of AMYLOID. As the amyloid deposits enlarge they displace normal tissue structures, causing disruption of function. Various signs and symptoms depend on the location and size of the deposits.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Because the cardiovascular system (CVS) side-effects of cyclooxygenase-2 (COX-2) selective inhibitors have recently been questioned, we aimed to compare the renal and haemodynamic effects of cyclooxygenase selective (celecoxib and rofecoxib) and non-selective non-steroidal anti-inflammatory drugs (NSAIDs) (indomethacin) in patients with renal amyloidosis secondary to rheumatological diseases who required anti-inflammatory agents and are taking maximum tolerable dose of angiotensin-converting enzyme inhibitors." | 9.12 | Effect of indomethacin and selective cyclooxygenase-2 inhibitors on proteinuria and renal function in patients with AA type renal amyloidosis. ( Akdag, I; Demircan, C; Dilek, K; Ersoy, A; Gullulu, M; Kahvecioglu, S; Yurtkuran, M, 2006) |
| "Because the cardiovascular system (CVS) side-effects of cyclooxygenase-2 (COX-2) selective inhibitors have recently been questioned, we aimed to compare the renal and haemodynamic effects of cyclooxygenase selective (celecoxib and rofecoxib) and non-selective non-steroidal anti-inflammatory drugs (NSAIDs) (indomethacin) in patients with renal amyloidosis secondary to rheumatological diseases who required anti-inflammatory agents and are taking maximum tolerable dose of angiotensin-converting enzyme inhibitors." | 5.12 | Effect of indomethacin and selective cyclooxygenase-2 inhibitors on proteinuria and renal function in patients with AA type renal amyloidosis. ( Akdag, I; Demircan, C; Dilek, K; Ersoy, A; Gullulu, M; Kahvecioglu, S; Yurtkuran, M, 2006) |
| "Flurbiprofen (1) analogues were obtained with enhanced anti-inflammatory and antiamyloidogenic properties compared to 1, however, esterification led to elevated Aβ(1-42) levels." | 1.37 | Inhibition of amyloidogenesis by nonsteroidal anti-inflammatory drugs and their hybrid nitrates. ( Abdul-Hay, S; Qin, Z; Schiefer, IT; Thatcher, GR; Vanni, M; Wang, H, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (44.44) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schiefer, IT | 1 |
| Abdul-Hay, S | 1 |
| Wang, H | 1 |
| Vanni, M | 1 |
| Qin, Z | 1 |
| Thatcher, GR | 1 |
| Guo, JT | 1 |
| Yu, J | 1 |
| Grass, D | 1 |
| de Beer, FC | 1 |
| Kindy, MS | 1 |
| Kahvecioglu, S | 1 |
| Dilek, K | 1 |
| Akdag, I | 1 |
| Gullulu, M | 1 |
| Demircan, C | 1 |
| Ersoy, A | 1 |
| Yurtkuran, M | 1 |
| Kimura, K | 1 |
| Ogawa, K | 1 |
| Sato, K | 1 |
| Tokuhara, S | 1 |
| Otsuka, M | 1 |
| Matsunaga, Y | 1 |
| Tsubura, E | 1 |
| Okabe, H | 1 |
| Sakamoto, S | 1 |
| Chijiiwa, Y | 1 |
| Misawa, T | 1 |
| Nawata, H | 1 |
| Nakayama, K | 1 |
| Duda, SH | 1 |
| Raible, RT | 1 |
| Risler, T | 1 |
| Huppert, PE | 1 |
| Brambs, HJ | 1 |
| Gregor, M | 1 |
| Feest, TG | 1 |
| Wallis, JP | 1 |
| Anttila, R | 1 |
| Koskiahde, V | 1 |
| Laaksonen, AL | 1 |
| Mäkinen, E | 1 |
| Rönning, O | 1 |
| Strauss, RG | 1 |
| Schubert, WK | 1 |
| McAdams, AJ | 1 |
1 trial available for indomethacin and Amyloidosis
| Article | Year |
|---|---|
Effect of indomethacin and selective cyclooxygenase-2 inhibitors on proteinuria and renal function in patients with AA type renal amyloidosis.
Topics: Adult; Amyloidosis; Cyclooxygenase 2 Inhibitors; Drug Therapy, Combination; Female; Humans; Indometh | 2006 |
8 other studies available for indomethacin and Amyloidosis
| Article | Year |
|---|---|
Inhibition of amyloidogenesis by nonsteroidal anti-inflammatory drugs and their hybrid nitrates.
Topics: Amyloid beta-Peptides; Amyloidosis; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non | 2011 |
Inflammation-dependent cerebral deposition of serum amyloid a protein in a mouse model of amyloidosis.
Topics: Age Factors; Amyloidosis; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Northern; Brai | 2002 |
Changes in natural killer activities in experimental secondary amyloidosis.
Topics: Amyloid; Amyloidosis; Animals; Caseins; Cell Adhesion; Immune Tolerance; Indomethacin; Killer Cells, | 1984 |
[A case of ankylosing spondylitis with secondary intestinal amyloidosis].
Topics: Adult; Amyloidosis; Humans; Indomethacin; Intestinal Diseases; Male; Spondylitis, Ankylosing | 1994 |
[Therapeutic bilateral renal artery embolization in the nephrotic syndrome].
Topics: Amyloidosis; Captopril; Cardiomyopathies; Contraindications; Creatinine; Crohn Disease; Drug Therapy | 1994 |
Familial nephropathic amyloidosis associated with indomethacin responsive fever.
Topics: Amyloidosis; Female; Fever; Genes, Dominant; Humans; Indomethacin; Kidney Diseases; Middle Aged | 1985 |
[Special problems of juvenile rheumatoid arthritis].
Topics: Adrenal Cortex Hormones; Amyloidosis; Arthritis, Juvenile; Bone Development; Child; Chloroquine; Dia | 1974 |
Amyloidosis in childhood.
Topics: Adolescent; Amyloidosis; Arthritis, Juvenile; Female; Hematuria; Humans; Indomethacin; Kidney; Liver | 1969 |