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indomethacin and Alveolar Bone Atrophy

indomethacin has been researched along with Alveolar Bone Atrophy in 9 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Research Excerpts

ExcerptRelevanceReference
"We examined the effects of calcium gluconate, an anti-inflammatory calcium salt, on ligature-induced experimental periodontitis and related alveolar bone loss."7.77Effects of calcium gluconate on experimental periodontitis and alveolar bone loss in rats. ( Cho, HR; Kang, SJ; Ku, SK; Lee, YJ; Sung, YS, 2011)
"We investigated the effect of etoricoxib, a selective cyclooxygenase-2 inhibitor, and indomethacin, a non-selective cyclooxygenase inhibitor, on experimental periodontitis, and compared their gastrointestinal side effects."7.74Comparison of etoricoxib and indomethacin for the treatment of experimental periodontitis in rats. ( Azoubel, MC; Bezerra, D; Brito, GA; Menezes, AM; Oriá, RB; Ribeiro, RA, 2007)
"We examined the effects of calcium gluconate, an anti-inflammatory calcium salt, on ligature-induced experimental periodontitis and related alveolar bone loss."3.77Effects of calcium gluconate on experimental periodontitis and alveolar bone loss in rats. ( Cho, HR; Kang, SJ; Ku, SK; Lee, YJ; Sung, YS, 2011)
"We investigated the effect of etoricoxib, a selective cyclooxygenase-2 inhibitor, and indomethacin, a non-selective cyclooxygenase inhibitor, on experimental periodontitis, and compared their gastrointestinal side effects."3.74Comparison of etoricoxib and indomethacin for the treatment of experimental periodontitis in rats. ( Azoubel, MC; Bezerra, D; Brito, GA; Menezes, AM; Oriá, RB; Ribeiro, RA, 2007)
"Arachidonic acid metabolites have been implicated in development of periodontal disease, especially those derived from the cyclo-oxygenase (COX) pathway."1.35Role of systemic and local administration of selective inhibitors of cyclo-oxygenase 1 and 2 in an experimental model of periodontal disease in rats. ( Caliari, MV; Duarte, ID; Francischi, JN; Maltos, KL; Pacheco, CM; Queiroz-Junior, CM, 2009)
"Indomethacin, which is a prostaglandin inhibitor, decreased the osteoclast formation induced by the bacterial sonicates."1.31Effects of whole cell sonicates of Treponema lecithinolyticum on osteoclast differentiation. ( Choi, BK; Jeong, GJ; Kang, JH; Lee, HJ; Ohk, SH; Yoo, YJ, 2001)
"Extracts of human periapical granulomas were tested for the presence of bone-resorbing activity."1.29Characterization of bone-resorbing activity in human periapical lesions. ( Stashenko, P; Wang, CY, 1993)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (33.33)18.2507
2000's4 (44.44)29.6817
2010's2 (22.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Queiroz-Junior, CM1
Pacheco, CM1
Maltos, KL1
Caliari, MV1
Duarte, ID1
Francischi, JN1
Ku, SK1
Cho, HR1
Sung, YS1
Kang, SJ1
Lee, YJ1
Oka, H1
Miyauchi, M1
Furusho, H1
Nishihara, T1
Takata, T1
Azoubel, MC1
Menezes, AM1
Bezerra, D1
Oriá, RB1
Ribeiro, RA2
Brito, GA2
Lasfargues, JJ1
Saffar, JL1
Howell, TH1
Williams, RC1
Wang, CY1
Stashenko, P1
Bezerra, MM1
de Lima, V1
Alencar, VB1
Vieira, IB1
Rocha, FA1
Choi, BK1
Ohk, SH1
Lee, HJ1
Kang, JH1
Jeong, GJ1
Yoo, YJ1

Reviews

1 review available for indomethacin and Alveolar Bone Atrophy

ArticleYear
Nonsteroidal antiinflammatory drugs as inhibitors of periodontal disease progression.
    Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists, 1993, Volume: 4, Issue:2

    Topics: Alveolar Bone Loss; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bone Resorption; Flurbiprofen;

1993

Other Studies

8 other studies available for indomethacin and Alveolar Bone Atrophy

ArticleYear
Role of systemic and local administration of selective inhibitors of cyclo-oxygenase 1 and 2 in an experimental model of periodontal disease in rats.
    Journal of periodontal research, 2009, Volume: 44, Issue:2

    Topics: Alveolar Bone Loss; Animals; Arachidonic Acid; Celecoxib; Cyclooxygenase Inhibitors; Disease Models,

2009
Effects of calcium gluconate on experimental periodontitis and alveolar bone loss in rats.
    Basic & clinical pharmacology & toxicology, 2011, Volume: 108, Issue:4

    Topics: Alveolar Bone Loss; Analysis of Variance; Animals; Anti-Inflammatory Agents; Body Weight; Calcium Gl

2011
Oral administration of prostaglandin E(2)-specific receptor 4 antagonist inhibits lipopolysaccharide-induced osteoclastogenesis in rat periodontal tissue.
    Journal of periodontology, 2012, Volume: 83, Issue:4

    Topics: Aggregatibacter actinomycetemcomitans; Alveolar Bone Loss; Alveolar Process; Animals; Bone Resorptio

2012
Comparison of etoricoxib and indomethacin for the treatment of experimental periodontitis in rats.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2007, Volume: 40, Issue:1

    Topics: Alveolar Bone Loss; Animals; Cyclooxygenase Inhibitors; Etoricoxib; Female; Gastric Mucosa; Indometh

2007
Inhibition of prostanoid synthesis depresses alveolar bone resorption but enhances root resorption in the rat.
    The Anatomical record, 1993, Volume: 237, Issue:4

    Topics: Adaptation, Physiological; Alveolar Bone Loss; Animals; Dental Cementum; Indomethacin; Male; Osteocl

1993
Characterization of bone-resorbing activity in human periapical lesions.
    Journal of endodontics, 1993, Volume: 19, Issue:3

    Topics: Alveolar Bone Loss; Analysis of Variance; Animals; Bone Resorption; Dinoprostone; Humans; Indomethac

1993
Selective cyclooxygenase-2 inhibition prevents alveolar bone loss in experimental periodontitis in rats.
    Journal of periodontology, 2000, Volume: 71, Issue:6

    Topics: Alveolar Bone Loss; Alveolar Process; Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Weight;

2000
Effects of whole cell sonicates of Treponema lecithinolyticum on osteoclast differentiation.
    Journal of periodontology, 2001, Volume: 72, Issue:9

    Topics: Alveolar Bone Loss; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bone Marrow Cells; Carrier Pro

2001