indomethacin has been researched along with Alloxan Diabetes in 127 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Diabetes was induced in rats by a single dose of streptozotocin (STZ) followed by gastric ulceration using indomethacin, and melatonin's action was studied by its application prior to indomethacin exposure." | 7.77 | Upregulation of collagenase-1 and -3 in indomethacin-induced gastric ulcer in diabetic rats: role of melatonin. ( Pradeepkumar Singh, L; Swarnakar, S; Vivek Sharma, A, 2011) |
| "Effects of acute sodium salicylate infusion on glucagon and epinephrine responses to insulin hypoglycemia were studied in streptozotocin diabetic and age-matched control rats." | 7.67 | Effects of acute sodium salicylate on the abnormal counterregulatory glucagon and epinephrine responses to insulin hypoglycemia in diabetic rats. ( Patel, DG, 1989) |
| "Of all drugs used in the treatment of Type 2 diabetes, the insulin sensitizers thiazolidinediones (e." | 5.36 | Gastroprotective effects of the insulin sensitizers rosiglitazone and metformin against indomethacin-induced gastric ulcers in Type 2 diabetic rats. ( Abdel-Gaber, SA; Ashour, OM; Fouad, AA; Morsy, MA, 2010) |
| " Diabetes was induced in rats by a single dose of streptozotocin (STZ) followed by gastric ulceration using indomethacin, and melatonin's action was studied by its application prior to indomethacin exposure." | 3.77 | Upregulation of collagenase-1 and -3 in indomethacin-induced gastric ulcer in diabetic rats: role of melatonin. ( Pradeepkumar Singh, L; Swarnakar, S; Vivek Sharma, A, 2011) |
| " In nondiabetic rats, stimulation of the endothelium by locally administered ACh or bradykinin-induced transient renal hyperemia." | 3.74 | In vivo regulation of endothelium-dependent vasodilation in the rat renal circulation and the effect of streptozotocin-induced diabetes. ( Edgley, AJ; Evans, RG; Parkington, HC; Skordilis, C; Tare, M, 2008) |
| " Using an animal model of diabetes (alloxan-induced hyperglycaemia in mice), a model of gastric ulcer (indomethacin-induced gastric lesion in rats), and a model of bronchial asthma (ovalbumin-induced allergic bronchospasm in guinea pigs), a potential therapeutic effect was tested in known antioxidant drugs (alpha-tocopherol, ubiquinone), the thio-compound mesna, and drugs with a possible antioxidant effect (substances derived from the ergoline structure: 6-hydroxynicotinic acid and 4-hydroxypyridine)." | 3.70 | Effects of known and potential antioxidants on animal models of pathological processes (diabetes, gastric lesions, allergic bronchospasm). ( Grossmann, V; Stetinová, V, 2000) |
| ""In vitro" isometric developed tension (IDT) and frequency of contractions (FC), glucose (Glu), glycogen (GLY) and triglyceride (TG) metabolism, as well as prostaglandin PGE2 and PGE1 production, were studied in uterine strips and in embryos isolated from controls and diabetic rats at day 10 of pregnancy." | 3.68 | Glucose, glycogen and triglyceride metabolism, as well as prostaglandin production in uterine strips and in embryos from diabetic pregnant rats. Influences of the presence of substrate in the incubation medium. ( Catafau, JR; Gimeno, AL; Gimeno, MA; Gomez, G; Gonzalez, ET; Jawerbaum, A; Rodriguez, RR, 1993) |
| "Effects of acute sodium salicylate infusion on glucagon and epinephrine responses to insulin hypoglycemia were studied in streptozotocin diabetic and age-matched control rats." | 3.67 | Effects of acute sodium salicylate on the abnormal counterregulatory glucagon and epinephrine responses to insulin hypoglycemia in diabetic rats. ( Patel, DG, 1989) |
| "Atorvastatin treatment did not affect glycemia levels." | 1.43 | Treatment with high dose of atorvastatin reduces vascular injury in diabetic rats. ( Botelho, T; de Batista, PR; Padilha, AS; Ribeiro-Júnior, RF; Simões, FV; Vassallo, DV, 2016) |
| "Treatment with indomethacin reduced IP response in the hyper-reactive model, and did not produce any change in diabetic model with hyper-reactive airways, indicating further disruption of the COX pathway." | 1.43 | Deterioration of epithelium mediated mechanisms in diabetic-antigen sensitized airways of guinea pigs. ( Bano, S; Kambadur, M; Mohammad, F; Swati, O, 2016) |
| " Taken together these data indicate that deletion of PTP1B protected endothelial function by compensating the reduction in NO bioavailability by increasing COX-2-mediated release of the vasodilator prostanoid PGI2, in T1DM mice." | 1.42 | Deletion of Protein Tyrosine Phosphatase 1B (PTP1B) Enhances Endothelial Cyclooxygenase 2 Expression and Protects Mice from Type 1 Diabetes-Induced Endothelial Dysfunction. ( Anderson, R; Belin de Chantemèle, EJ; Herre, DJ; Herren, DJ; Huby, AC; Norman, JB; Tremblay, ML, 2015) |
| "Of all drugs used in the treatment of Type 2 diabetes, the insulin sensitizers thiazolidinediones (e." | 1.36 | Gastroprotective effects of the insulin sensitizers rosiglitazone and metformin against indomethacin-induced gastric ulcers in Type 2 diabetic rats. ( Abdel-Gaber, SA; Ashour, OM; Fouad, AA; Morsy, MA, 2010) |
| "Pretreatment with flavone enhanced relaxant effects to endothelium-dependent vasodilator acetylcholine (ACh) and attenuated contractile effects to alpha(1)-receptor agonist phenylephrine (PE) in WKY aortae compared to those observed in control aortic rings." | 1.34 | Modulation of vascular reactivity in normal, hypertensive and diabetic rat aortae by a non-antioxidant flavonoid. ( Achike, FI; Ajay, M; Mustafa, MR, 2007) |
| "Pioglitazone treatment reduced blood pressure without having any significant effect on blood glucose level and body weight of STZ-diabetic rats." | 1.33 | Pioglitazone, a PPARgamma agonist, restores endothelial function in aorta of streptozotocin-induced diabetic rats. ( Balaraman, R; Majithiya, JB; Paramar, AN, 2005) |
| "This indomethacin-resistant EDR was weaker in the STZ group than in the controls." | 1.33 | Specific impairment of endothelium-derived hyperpolarizing factor-type relaxation in mesenteric arteries from streptozotocin-induced diabetic mice. ( Kamata, K; Kobayashi, T; Matsumoto, T; Miyamori, K, 2006) |
| "The effect of hyperlipemia associated with diabetes on the contractility of resistance arteries to prostaglandin F2alpha (PGF2alpha) was investigated employing 4 weeks simultaneously hyperlipemic-diabetic (HD), hyperlipemic (H), diabetic (D) and normal hamsters (controls, C)." | 1.32 | The contractile response of the mesenteric resistance arteries to prostaglandin F2alpha; effects of simultaneous hyperlipemia-diabetes. ( Georgescu, A; Popov, D, 2003) |
| " The dosage of 230 mg/kg of nicotinamide given intraperitoneally 15 min before STZ administration (65 mg/kg i." | 1.32 | Alterations in vascular endothelial function in the aorta and mesenteric artery in type II diabetic rats. ( Kamata, K; Kobayashi, T; Matsumoto, T; Wakabayashi, K, 2004) |
| "Insulin-dependent diabetes mellitus (IDDM) is an autoimmune disease believed to be caused by an inflammatory process in the pancreas leading to selective destruction of the beta cells." | 1.31 | COX-2 inhibition prevents insulin-dependent diabetes in low-dose streptozotocin-treated mice. ( Floyd, RA; Jacob, JM; Kotake, Y; Tabatabaie, T; Waldon, AM, 2000) |
| " The dose-response curve for methoxamine was shifted to the right and the maximum contractile response was impaired in mesenteric arterial beds from diabetic rats." | 1.30 | Possible modulation by endothelin-1, nitric oxide, prostaglandin I2 and thromboxane A2 of vasoconstriction induced by an alpha-agonist in mesenteric arterial bed from diabetic rats. ( Kamata, K; Makino, A, 1998) |
| "Indomethacin treatment did not affect endothelium-dependent relaxation in the control solution but partially restored the response to ACh in elevated glucose." | 1.29 | Magnesium modulates endothelial dysfunction produced by elevated glucose incubation. ( Duhault, J; Félétou, M; Rasetti, C, 1994) |
| "Phentolamine pretreatment (5 mumol." | 1.28 | Increased vasoconstrictor response to noradrenaline in femoral vascular bed of diabetic dogs. Is thromboxane A2 involved? ( Ballagi-Pordány, G; Hadházy, P; Koltai, MZ; Pogátsa, G; Rösen, P, 1990) |
| " Met (1 X 10(-6) M) increased the tension of both normal and diabetic atria, but in diabetic atria, the dose-response curve to Met was shifted to the left and the efficacy of Met was enhanced." | 1.27 | Hypersensitivity to methoxamine in atria isolated from streptozotocin-induced diabetic rats. ( Canga, L; Sterin-Borda, L, 1986) |
| "Nifedipine was more potent in inhibiting the contraction to K+ and serotonin in WKY diabetic arteries as compared with WKY controls." | 1.27 | Effect of diabetes on vascular smooth muscle function in normotensive and spontaneously hypertensive rat mesenteric artery. ( Agrawal, DK; McNeill, JH, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 29 (22.83) | 18.7374 |
| 1990's | 42 (33.07) | 18.2507 |
| 2000's | 35 (27.56) | 29.6817 |
| 2010's | 20 (15.75) | 24.3611 |
| 2020's | 1 (0.79) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, H | 1 |
| Simonsen, U | 1 |
| Aalkjaer, C | 1 |
| Podvigina, TT | 3 |
| Bagaeva, TP | 1 |
| Filaretova, LP | 3 |
| Saidullah, B | 1 |
| Muralidhar, K | 1 |
| Fahim, M | 1 |
| Ho, N | 1 |
| Brookshire, BR | 1 |
| Clark, JE | 1 |
| Lucki, I | 1 |
| Herren, DJ | 1 |
| Herre, DJ | 1 |
| Norman, JB | 1 |
| Anderson, R | 1 |
| Tremblay, ML | 1 |
| Huby, AC | 1 |
| Belin de Chantemèle, EJ | 1 |
| Mori, A | 2 |
| Suzawa, H | 1 |
| Sakamoto, K | 2 |
| Nakahara, T | 2 |
| Ishii, K | 2 |
| Vladimirova, IA | 1 |
| Philyppov, IB | 1 |
| Kulieva, EM | 1 |
| Paduraru, ON | 1 |
| Shuba, YY | 1 |
| Shuba, YM | 1 |
| Simões, FV | 1 |
| de Batista, PR | 1 |
| Botelho, T | 1 |
| Ribeiro-Júnior, RF | 1 |
| Padilha, AS | 1 |
| Vassallo, DV | 1 |
| Bano, S | 1 |
| Swati, O | 1 |
| Kambadur, M | 1 |
| Mohammad, F | 1 |
| Jiménez-Andrade, GY | 1 |
| Reyes-García, G | 1 |
| Sereno, G | 1 |
| Ceballos-Reyes, G | 1 |
| Vidal-Cantú, GC | 1 |
| Granados-Soto, V | 1 |
| Edgley, AJ | 1 |
| Tare, M | 3 |
| Evans, RG | 1 |
| Skordilis, C | 1 |
| Parkington, HC | 3 |
| Okon, EB | 1 |
| Golbabaie, A | 1 |
| Breemen, Cv | 1 |
| Bujalska, M | 1 |
| Zayachkivska, O | 1 |
| Gzregotsky, M | 1 |
| Ferentc, M | 1 |
| Yaschenko, A | 1 |
| Urbanovych, A | 1 |
| Morsy, MA | 1 |
| Ashour, OM | 1 |
| Fouad, AA | 1 |
| Abdel-Gaber, SA | 1 |
| Marrachelli, VG | 3 |
| Miranda, FJ | 7 |
| Centeno, JM | 6 |
| Salom, JB | 2 |
| Torregrosa, G | 2 |
| Jover-Mengual, T | 2 |
| Pérez, AM | 2 |
| Moro, MA | 1 |
| Alborch, E | 7 |
| Burguete, MC | 1 |
| Castelló-Ruiz, M | 1 |
| Leo, CH | 1 |
| Hart, JL | 1 |
| Woodman, OL | 2 |
| Pradeepkumar Singh, L | 1 |
| Vivek Sharma, A | 1 |
| Swarnakar, S | 1 |
| Suzuki, S | 1 |
| Granstam, SO | 1 |
| Granstam, E | 1 |
| Roganović, J | 1 |
| Radenković, M | 1 |
| Tanić, N | 2 |
| Petrović, N | 1 |
| Stojić, D | 1 |
| Bagaeva, TR | 2 |
| Morozova, OIu | 1 |
| Bobryshev, PY | 1 |
| Moharram, FA | 1 |
| Marzouk, MS | 1 |
| El-Shenawy, SM | 1 |
| Gaara, AH | 1 |
| El Kady, WM | 1 |
| Ramos-Alves, FE | 1 |
| de Queiroz, DB | 1 |
| Santos-Rocha, J | 1 |
| Duarte, GP | 1 |
| Xavier, FE | 1 |
| Liu, J | 1 |
| Zhang, QJ | 1 |
| Guo, BC | 1 |
| Cao, DY | 1 |
| Wang, KM | 1 |
| Coppey, LJ | 1 |
| Gellett, JS | 1 |
| Yorek, MA | 1 |
| Georgescu, A | 1 |
| Popov, D | 1 |
| Matsumoto, T | 3 |
| Wakabayashi, K | 1 |
| Kobayashi, T | 3 |
| Kamata, K | 6 |
| Wigg, SJ | 2 |
| Forbes, J | 1 |
| Cooper, ME | 1 |
| Thomas, MC | 1 |
| Coleman, HA | 1 |
| O'Brien, RC | 2 |
| Carvalho Leone, AF | 1 |
| Coelho, EB | 1 |
| Roghani, M | 1 |
| Baluchnejadmojarad, T | 1 |
| Vaez-Mahdavi, MR | 1 |
| Roghani-Dehkordi, F | 1 |
| Ettarh, RR | 1 |
| Arikawe, AP | 1 |
| Majithiya, JB | 1 |
| Paramar, AN | 1 |
| Balaraman, R | 1 |
| Suresh, Y | 1 |
| Das, UN | 1 |
| Alabadí, JA | 5 |
| Lloréns, S | 5 |
| Miyamori, K | 1 |
| Hosokawa, M | 2 |
| Ramos, KM | 1 |
| Jiang, Y | 1 |
| Svensson, CI | 2 |
| Calcutt, NA | 2 |
| Ajay, M | 1 |
| Achike, FI | 1 |
| Mustafa, MR | 1 |
| Malakul, W | 1 |
| Thirawarapan, S | 1 |
| Suvitayavat, W | 1 |
| Mic, AA | 1 |
| Mic, FA | 1 |
| Tatu, CA | 1 |
| Ionac, M | 1 |
| Ordodi, VL | 1 |
| Paunescu, V | 1 |
| Chen, YJ | 1 |
| Li, J | 1 |
| Quilley, J | 2 |
| Kim, YC | 1 |
| Brodows, RG | 1 |
| Rösen, P | 7 |
| Eckel, J | 1 |
| Reinauer, H | 1 |
| Koltai, MZ | 6 |
| Hadházy, P | 6 |
| Malomvölgyi, B | 2 |
| Wagner, M | 2 |
| Pogátsa, G | 7 |
| Peredo, H | 1 |
| Agostini, MD | 1 |
| Gimeno, MF | 2 |
| Borda, ES | 1 |
| Fortes, ZB | 1 |
| Garcia Leme, J | 1 |
| Scivoletto, R | 1 |
| Axelrod, L | 2 |
| Cornelius, P | 1 |
| Schrör, K | 1 |
| Palik, I | 1 |
| Magyar, K | 1 |
| Sterin-Borda, L | 2 |
| Gimeno, M | 1 |
| Borda, E | 1 |
| del Castillo, E | 2 |
| Gimeno, AL | 4 |
| Félétou, M | 1 |
| Rasetti, C | 1 |
| Duhault, J | 1 |
| Tesfamariam, B | 1 |
| Brown, ML | 1 |
| Cohen, RA | 1 |
| Mahadevan, P | 2 |
| Larkins, RG | 3 |
| Fraser, JR | 2 |
| Fosang, AJ | 1 |
| Dunlop, ME | 2 |
| Bertuglia, S | 1 |
| Malandrino, S | 1 |
| Colantuoni, A | 1 |
| Taylor, PD | 2 |
| Poston, L | 3 |
| Jawerbaum, A | 2 |
| Gonzalez, ET | 2 |
| Catafau, JR | 1 |
| Rodriguez, RR | 1 |
| Gomez, G | 1 |
| Gimeno, MA | 2 |
| Sikorski, BW | 2 |
| Hodgson, WC | 2 |
| King, RG | 2 |
| Ahlgren, SC | 1 |
| Levine, JD | 1 |
| Ballhausen, T | 2 |
| Bloch, W | 1 |
| Addicks, K | 1 |
| Inman, SR | 1 |
| Porter, JP | 1 |
| Fleming, JT | 1 |
| Stockklauser, K | 1 |
| el-Kashef, H | 1 |
| Myers, TO | 1 |
| Messina, EJ | 1 |
| Kondoh, H | 1 |
| Pieper, GM | 4 |
| Langenstroer, P | 1 |
| Siebeneich, W | 1 |
| Pósa, I | 2 |
| Kocsis, E | 2 |
| Winkler, G | 1 |
| Makino, A | 1 |
| Holemans, K | 1 |
| Gerber, RT | 1 |
| Meurrens, K | 1 |
| De Clerck, F | 1 |
| Van Assche, FA | 1 |
| Wentzel, P | 1 |
| Welsh, N | 1 |
| Eriksson, UJ | 1 |
| Fujii, E | 1 |
| Yoshioka, T | 1 |
| Wada, K | 1 |
| Ishida, H | 1 |
| Irie, K | 1 |
| Muraki, T | 1 |
| Peredo, HA | 1 |
| Feleder, EC | 1 |
| Adler-Graschinsky, E | 1 |
| Karasu, C | 1 |
| Lai, CS | 1 |
| Pflueger, AC | 1 |
| Gross, JM | 1 |
| Knox, FG | 1 |
| Cloutier, F | 1 |
| Couture, R | 1 |
| Ruiz de Apodaca, RF | 4 |
| Tabatabaie, T | 1 |
| Waldon, AM | 1 |
| Jacob, JM | 1 |
| Floyd, RA | 1 |
| Kotake, Y | 1 |
| Pacher, P | 1 |
| Nieszner, E | 1 |
| De Vriese, AS | 1 |
| Van de Voorde, J | 1 |
| Blom, HJ | 1 |
| Vanhoutte, PM | 1 |
| Verbeke, M | 1 |
| Lameire, NH | 1 |
| Stetinová, V | 1 |
| Grossmann, V | 1 |
| Timar-Peregrin, A | 1 |
| Guy, RG | 1 |
| Tonta, MA | 1 |
| Meredith, IT | 1 |
| Freshwater, JD | 1 |
| Malmberg, AB | 1 |
| Warchalowski, GA | 1 |
| Strausser, HR | 1 |
| Uranga, J | 1 |
| Aranyi, Z | 1 |
| Ballagi-Pordány, G | 3 |
| McCarthy, AL | 1 |
| Thomas, CR | 1 |
| Zochodne, DW | 1 |
| Ho, LT | 1 |
| Azadzoi, KM | 1 |
| Saenz de Tejada, I | 1 |
| Chang, KS | 1 |
| Stevens, WC | 1 |
| Pinna, C | 1 |
| Caratozzolo, O | 1 |
| Puglisi, L | 1 |
| Perico, N | 1 |
| Benigni, A | 1 |
| Gabanelli, M | 1 |
| Piccinelli, A | 1 |
| Ròg, M | 1 |
| De Riva, C | 1 |
| Remuzzi, G | 1 |
| Xu, WX | 1 |
| Yu, JR | 1 |
| McCormack, AJ | 1 |
| Hak, LJ | 1 |
| Finn, WF | 1 |
| Fulton, DJ | 1 |
| Mayhan, WG | 1 |
| Simmons, LK | 1 |
| Sharpe, GM | 1 |
| Sarubbi, D | 1 |
| Hattori, Y | 1 |
| Kawasaki, H | 1 |
| Abe, K | 1 |
| Kanno, M | 1 |
| Amemiya, K | 1 |
| Suzuki, J | 1 |
| Kimura, M | 1 |
| Takiguchi, Y | 1 |
| Umemura, K | 1 |
| Hashimoto, H | 1 |
| Nakashima, M | 1 |
| Quyyumi, AA | 1 |
| Iaffaldano, R | 1 |
| Guerrero, JL | 1 |
| Ryan, CA | 1 |
| Powell, WJ | 1 |
| Hill, MA | 1 |
| Patel, DG | 1 |
| Canga, L | 1 |
| Kawamura, K | 1 |
| Dohl, T | 1 |
| Tamai, K | 1 |
| Shirakawa, M | 1 |
| Okamoto, H | 1 |
| Tsujimoto, A | 1 |
| Craven, PA | 1 |
| Caines, MA | 1 |
| DeRubertis, FR | 1 |
| Gross, GJ | 1 |
| Köszeghy, A | 1 |
| Agrawal, DK | 1 |
| McNeill, JH | 1 |
| Jensen, PK | 1 |
| Steven, K | 1 |
| Blaehr, H | 1 |
| Christiansen, JS | 1 |
| Parving, HH | 1 |
| Valle, CC | 1 |
| Hacad, E | 1 |
| Sudo, LS | 1 |
| Garcia-Leme, J | 1 |
| Macciocchi, EK | 1 |
| Linares, JA | 1 |
| Goldraij, A | 1 |
| Garlick, PJ | 1 |
| Preedy, VR | 1 |
| Reeds, PJ | 1 |
| Yue, DK | 1 |
| McLennan, S | 1 |
| Handelsman, DJ | 1 |
| Delbridge, L | 1 |
| Reeve, T | 1 |
| Turtle, JR | 1 |
| Kurose, H | 1 |
| Sonn, YM | 1 |
| Jafari, A | 1 |
| Birge, SJ | 1 |
| Avioli, LV | 1 |
| Kocialski, AB | 1 |
| Marozzi, FJ | 1 |
| Malone, MH | 1 |
127 other studies available for indomethacin and Alloxan Diabetes
| Article | Year |
|---|---|
A sex-specific, COX-derived/thromboxane receptor activator causes depolarization and vasoconstriction in male mice mesenteric resistance arteries.
Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Diabe | 2020 |
[GASTROPROTECTIVE EFFECT OF CORTICOTROPIN-RELEASING FACTOR IN STREPTOZOTOCIN-INDUCED DIABETIC RATS].
Topics: Animals; Corticotropin-Releasing Hormone; Diabetes Mellitus, Experimental; Gastric Mucosa; Gastritis | 2016 |
Onset of diabetes modulates the airway smooth muscle reactivity of guinea pigs: role of epithelial mediators.
Topics: Acetylcholine; Animals; Bronchi; Bronchoconstriction; Cyclooxygenase Inhibitors; Diabetes Mellitus, | 2014 |
Indomethacin reverses decreased hippocampal cell proliferation in streptozotocin-induced diabetic mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Glucose; Body Weight; Cell Proliferation; Co | 2015 |
Deletion of Protein Tyrosine Phosphatase 1B (PTP1B) Enhances Endothelial Cyclooxygenase 2 Expression and Protects Mice from Type 1 Diabetes-Induced Endothelial Dysfunction.
Topics: Animals; Aorta; Blood Glucose; Cells, Cultured; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Diabe | 2015 |
Vasodilator Effects of Elcatonin, a Synthetic Eel Calcitonin, on Retinal Blood Vessels in Rats.
Topics: Adenine; Adenylyl Cyclase Inhibitors; Animals; Calcitonin; Cyclooxygenase Inhibitors; Diabetes Melli | 2015 |
[Impact of diabetic complications on neuromuscular transmission in the smooth muscle of the bladder of rats with experimental diabetes].
Topics: Animals; Atropine; Cyclooxygenase 1; Cyclooxygenase 2; Cyclophosphamide; Cystitis; Diabetes Mellitus | 2015 |
Treatment with high dose of atorvastatin reduces vascular injury in diabetic rats.
Topics: Animals; Aorta; Atorvastatin; Cyclooxygenase 2; Diabetes Mellitus, Experimental; Endothelium, Vascul | 2016 |
Deterioration of epithelium mediated mechanisms in diabetic-antigen sensitized airways of guinea pigs.
Topics: Acetylcholine; Animals; Antigens, Bacterial; Bacterial Proteins; Bronchial Hyperreactivity; Bronchoc | 2016 |
Pyritinol reduces nociception and oxidative stress in diabetic rats.
Topics: Analgesics; Animals; Diabetes Mellitus, Experimental; Female; Indomethacin; Naltrexone; Oxadiazoles; | 2008 |
In vivo regulation of endothelium-dependent vasodilation in the rat renal circulation and the effect of streptozotocin-induced diabetes.
Topics: Acetylcholine; Anesthesia; Animals; Animals, Outbred Strains; Biological Factors; Blood Pressure; Br | 2008 |
Paracrine effects of endothelial cells in a diabetic mouse model: capacitative calcium entry stimulated thromboxane release.
Topics: Animals; Aorta; Calcium Signaling; Diabetes Mellitus, Experimental; Disease Models, Animal; Endothel | 2008 |
Effect of cannabinoid receptor agonists on streptozotocin-induced hyperalgesia in diabetic neuropathy.
Topics: Analgesics; Animals; Arachidonic Acids; Benzoxazines; Cannabinoids; Cyclooxygenase Inhibitors; Diabe | 2008 |
Effects of nitrosative stress and reactive oxygen-scavenging systems in esophageal physiopathy under streptozotocin-induced experimental hyperglycemia.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Disease Models, Animal; Esophagus; Glutathione P | 2008 |
Gastroprotective effects of the insulin sensitizers rosiglitazone and metformin against indomethacin-induced gastric ulcers in Type 2 diabetic rats.
Topics: Animals; Catalase; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dinoprostone; Gastric | 2010 |
Role of NO-synthases and cyclooxygenases in the hyperreactivity of male rabbit carotid artery to testosterone under experimental diabetes.
Topics: Animals; Apamin; Blood Glucose; Blotting, Western; Calcium; Carotid Arteries; Carotid Artery Disease | 2010 |
Mechanisms involved in the relaxant action of testosterone in the renal artery from male normoglycemic and diabetic rabbits.
Topics: Animals; Blood Glucose; Blotting, Western; Calcium; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygena | 2010 |
Impairment of both nitric oxide-mediated and EDHF-type relaxation in small mesenteric arteries from rats with streptozotocin-induced diabetes.
Topics: Animals; Biological Factors; Blood Glucose; Body Weight; Cyclooxygenase Inhibitors; Diabetes Mellitu | 2011 |
Upregulation of collagenase-1 and -3 in indomethacin-induced gastric ulcer in diabetic rats: role of melatonin.
Topics: Analysis of Variance; Animals; Collagenases; Diabetes Mellitus, Experimental; Drug Interactions; Gel | 2011 |
Vasodilation of retinal arterioles induced by activation of BKCa channels is attenuated in diabetic rats.
Topics: Acetylcholine; Animals; Blood Glucose; Blood Pressure; Cyclooxygenase Inhibitors; Diabetes Mellitus, | 2011 |
Endothelin-induced changes in blood flow in STZ-diabetic and non-diabetic rats: relation to nitric oxide synthase and cyclooxygenase inhibition.
Topics: Animals; Blood Pressure; Cyclooxygenase Inhibitors; Diabetes Mellitus, Experimental; Endothelin-1; H | 2011 |
Impairment of acetylcholine-mediated endothelium-dependent relaxation in isolated parotid artery of the alloxan-induced diabetic rabbit.
Topics: Acetylcholine; Alloxan; Animals; Arteries; Bradykinin; Cyclooxygenase Inhibitors; Diabetes Mellitus, | 2011 |
[Gastric mucosal susceptibility for ulcerogenic effect of indometacin at different time points of streptozotocin-induced diabetes development].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Glucose; Corticosterone; Diabetes Mellitus, | 2011 |
High sensitivity of gastric mucosa to ulcerogenic effect of indomethacin in rats with diabetes.
Topics: Adrenocorticotropic Hormone; Animals; Blood Glucose; Corticosterone; Diabetes Mellitus, Experimental | 2011 |
Polyphenolic profile and biological activity of Salvia splendens leaves.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Ascorbic Acid; Diabetes Mellitus, Experimental; Dis | 2012 |
Increased cyclooxygenase-2-derived prostanoids contributes to the hyperreactivity to noradrenaline in mesenteric resistance arteries from offspring of diabetic rats.
Topics: Animals; Cells, Cultured; Cyclooxygenase 2; Diabetes Mellitus, Experimental; Dinoprost; Endothelial | 2012 |
[Prostaglandin inhibitor indomethacin inhibits afferent activities of Adelta and C units in the saphenous nerve of diabetic hyperalgesic rats].
Topics: Afferent Pathways; Animals; Diabetes Mellitus, Experimental; Femoral Nerve; Hyperalgesia; Indomethac | 2002 |
Mediation of vascular relaxation in epineurial arterioles of the sciatic nerve: effect of diabetes in type 1 and type 2 diabetic rat models.
Topics: Acetylcholine; Animals; Arterioles; Biological Factors; Diabetes Mellitus, Experimental; Diabetes Me | 2003 |
The contractile response of the mesenteric resistance arteries to prostaglandin F2alpha; effects of simultaneous hyperlipemia-diabetes.
Topics: Aging; Animals; Blood Glucose; Cricetinae; Diabetes Mellitus, Experimental; Dinoprost; Disease Model | 2003 |
Alterations in vascular endothelial function in the aorta and mesenteric artery in type II diabetic rats.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Biological Factors; Chlorides; Diabetes Mellitus, Experimen | 2004 |
Early vitamin E supplementation attenuates diabetes-associated vascular dysfunction and the rise in protein kinase C-beta in mesenteric artery and ameliorates wall stiffness in femoral artery of Wistar rats.
Topics: Acetylcholine; Animals; Australia; Biomarkers; Blood Glucose; Body Weight; Diabetes Mellitus, Experi | 2004 |
Effects of prostanoids on phenylephrine-induced contractions in the mesenteric vascular bed of rats with streptozotocin-induced diabetes mellitus.
Topics: Adrenergic alpha-Agonists; Animals; Diabetes Mellitus, Experimental; Disease Models, Animal; Dose-Re | 2004 |
Mechanisms underlying quercetin-induced vasorelaxation in aorta of subchronic diabetic rats: an in vitro study.
Topics: Animals; Aorta, Thoracic; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Disease Model | 2004 |
Effects of diabetes and insulin resistance in pregnant rats on ex vivo vascular reaction to magnesium.
Topics: Alloxan; Animals; Aorta; Blood Glucose; Diabetes Mellitus, Experimental; Female; In Vitro Techniques | 2004 |
Pioglitazone, a PPARgamma agonist, restores endothelial function in aorta of streptozotocin-induced diabetic rats.
Topics: Acetylcholine; Animals; Aorta; Blood Pressure; Cyclooxygenase Inhibitors; Diabetes Mellitus, Experim | 2005 |
Differential effect of saturated, monounsaturated, and polyunsaturated fatty acids on alloxan-induced diabetes mellitus.
Topics: Alloxan; Animals; Arachidonic Acid; Blood Glucose; Body Weight; Catalase; Ceruloplasmin; Diabetes Me | 2006 |
Contribution of endothelin receptors and cyclooxygenase-derivatives to the altered response of the rabbit renal artery to endothelin-1 in diabetes.
Topics: Alloxan; Animals; Antihypertensive Agents; Cyclooxygenase Inhibitors; Diabetes Mellitus, Experimenta | 2006 |
Specific impairment of endothelium-derived hyperpolarizing factor-type relaxation in mesenteric arteries from streptozotocin-induced diabetic mice.
Topics: Acetylcholine; Animals; Biological Factors; Connexins; Diabetes Mellitus, Experimental; Dose-Respons | 2006 |
Altered arachidonic acid-mediated responses in the perfused kidney of the streptozotocin-induced diabetic rat.
Topics: Animals; Arachidonic Acid; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Diabetes M | 2006 |
Pathogenesis of spinally mediated hyperalgesia in diabetes.
Topics: Aldehyde Reductase; Animals; Cyclooxygenase 2; Diabetes Mellitus, Experimental; Disease Models, Anim | 2007 |
Modulation of vascular reactivity in normal, hypertensive and diabetic rat aortae by a non-antioxidant flavonoid.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Cyclic GMP; Cyclooxygenase Inhibitors; Diabetes Mellitus, E | 2007 |
Type 1 diabetes and hypercholesterolaemia reveal the contribution of endothelium-derived hyperpolarizing factor to endothelium-dependent relaxation of the rat aorta.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Apamin; Biological Factors; Blood Glucose; Body Weight; Cha | 2008 |
Indomethacin inhibits thymic involution in mice with streptozotocin-induced diabetes.
Topics: Animals; Apoptosis; Blood Glucose; Cells, Cultured; Corticosterone; Cyclooxygenase Inhibitors; Diabe | 2007 |
Deficient renal 20-HETE release in the diabetic rat is not the result of oxidative stress.
Topics: Aldehyde Reductase; Animals; Antioxidants; Arachidonic Acid; Benzothiazoles; Cyclic N-Oxides; Cycloo | 2008 |
Starvation stimulates pancreatic PGE content.
Topics: Animals; Diabetes Mellitus, Experimental; Indomethacin; Islets of Langerhans; Kinetics; Male; Prosta | 1983 |
Influence of bradykinin on glucose uptake and metabolism studied in isolated cardiac myocytes and isolated perfused rat hearts.
Topics: Animals; Bradykinin; Diabetes Mellitus, Experimental; Glucose; In Vitro Techniques; Indomethacin; In | 1983 |
Effects of cyclooxygenase inhibitors, prostaglandins F2 alpha and I2, on isolated coeliac and basilar arteries of alloxan-diabetic dogs.
Topics: Animals; Basilar Artery; Body Weight; Celiac Artery; Cyclooxygenase Inhibitors; Diabetes Mellitus, E | 1984 |
Hypersensitivity to norepinephrine in vasa deferentia from diabetic rats. Possible participation of metabolic products of arachidonic acid.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Carbon Radioisotopes; Catechols; Diabetes Mel | 1984 |
Vascular reactivity in diabetes mellitus: possible role of insulin on the endothelial cell.
Topics: Adrenalectomy; Animals; Arachidonic Acid; Arachidonic Acids; Blood Pressure; Bradykinin; Capillary P | 1984 |
Plasma prostaglandin levels and circulating fuel levels in rats with diabetic ketoacidosis: effects of cyclooxygenase inhibitors and of alpha and beta adrenergic blockade.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Glucose; Cyclooxygenase Inhibitors; Diabetes Mellitus, | 1984 |
Increased prostacyclin release from perfused hearts of acutely diabetic rats.
Topics: Animals; Arachidonic Acids; Biological Assay; Coronary Circulation; Diabetes Mellitus, Experimental; | 1980 |
Effects on prostaglandins F2 alpha, I2, and indomethacin on isolated coronary arteries from healthy and alloxan-diabetic dogs.
Topics: Animals; Arteries; Coronary Vessels; Diabetes Mellitus, Experimental; Dinoprost; Dogs; Drug Synergis | 1981 |
Prostacyclin (PGI2) and U-46619 stimulate coronary arteries from diabetic dogs and their action is influenced by inhibitors of prostaglandin biosynthesis.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Anti-Inflammatory Agent | 1981 |
Magnesium modulates endothelial dysfunction produced by elevated glucose incubation.
Topics: Acetylcholine; Analysis of Variance; Animals; Aorta; Diabetes Mellitus, Experimental; Disease Models | 1994 |
15-Hydroxyeicosatetraenoic acid and diabetic endothelial dysfunction in rabbit aorta.
Topics: Acetylcholine; Animals; Aorta, Abdominal; Bridged Bicyclo Compounds, Heterocyclic; Cytochrome P-450 | 1995 |
Increased hyaluronan production in the glomeruli from diabetic rats: a link between glucose-induced prostaglandin production and reduced sulphated proteoglycan.
Topics: Animals; Cells, Cultured; Chondroitin Sulfate Proteoglycans; Diabetes Mellitus, Experimental; Dinopr | 1995 |
Effects of the natural flavonoid delphinidin on diabetic microangiopathy.
Topics: Acetylcholine; Animals; Anthocyanins; Benzopyrans; Blood Glucose; Blood Pressure; Body Weight; Capil | 1995 |
The effect of hyperglycaemia on function of rat isolated mesenteric resistance artery.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Endothelium, Vascular; Female; Hyperglycemia; In | 1994 |
Glucose, glycogen and triglyceride metabolism, as well as prostaglandin production in uterine strips and in embryos from diabetic pregnant rats. Influences of the presence of substrate in the incubation medium.
Topics: Alprostadil; Animals; Culture Techniques; Diabetes Mellitus, Experimental; Dinoprostone; Female; Fet | 1993 |
Effects of haemoglobin and N-nitro-L-arginine on constrictor and dilator responses of aortic rings from streptozotocin diabetic rats.
Topics: Acetylcholine; Animals; Aorta; Arginine; Body Weight; Diabetes Mellitus, Experimental; Hemoglobins; | 1993 |
Mechanical hyperalgesia in streptozotocin-diabetic rats.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Adenylate Cyclase Toxin; Animals; Diabetes Mellit | 1993 |
Effect of prostaglandin E2 and hyaluronan on mesangial cell proliferation. A potential contribution to glomerular hypercellularity in diabetes.
Topics: Animals; Cell Division; Cells, Cultured; Cyclooxygenase Inhibitors; Diabetes Mellitus, Experimental; | 1996 |
Endothelial relaxation is disturbed by oxidative stress in the diabetic rat heart: influence of tocopherol as antioxidant.
Topics: Aging; Animals; Antioxidants; Catecholamines; Coronary Circulation; Diabetes Mellitus, Experimental; | 1995 |
Reduced renal microvascular reactivity to angiotensin II in diabetic rats.
Topics: Angiotensin II; Animals; Arterioles; Capillary Resistance; Diabetes Mellitus, Experimental; Indometh | 1994 |
Impairment of endothelium dependent relaxation in the diabetic rat heart: mechanisms and implications.
Topics: Animals; Antioxidants; Coronary Circulation; Cyclooxygenase Inhibitors; Diabetes Mellitus, Experimen | 1996 |
Hyperglycemia increased the responsiveness of isolated rabbit's pulmonary arterial rings to serotonin.
Topics: Animals; Cyclooxygenase Inhibitors; Diabetes Mellitus, Experimental; In Vitro Techniques; Indomethac | 1996 |
Depressed arteriolar responsiveness to norepinephrine in streptozotocin-induced diabetes in the rat.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acid; Arterioles; Blood Glucose; Blood Pressur | 1996 |
Impairment of endothelium-dependent relaxation of the isolated basilar artery from streptozotocin-induced diabetic rats.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Animals; Basilar Artery; Diabetes Mellitus, Experimental | 1996 |
Endothelial dysfunction in the perfused kidney from the streptozotocin-induced diabetic rat.
Topics: 6-Ketoprostaglandin F1 alpha; Acetylcholine; Animals; Anticoagulants; Arachidonic Acids; Biological | 1997 |
Diabetic-induced endothelial dysfunction in rat aorta: role of hydroxyl radicals.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Catalase; Cyclooxygenase Inhibitors; Diabetes Mellitus, Exp | 1997 |
Characteristics of coronary endothelial dysfunction in experimental diabetes.
Topics: Acetylcholine; Animals; Arginine; Coronary Circulation; Coronary Vessels; Cyclic GMP; Cyclooxygenase | 1997 |
Possible modulation by endothelin-1, nitric oxide, prostaglandin I2 and thromboxane A2 of vasoconstriction induced by an alpha-agonist in mesenteric arterial bed from diabetic rats.
Topics: Adrenergic alpha-Agonists; Animals; Diabetes Mellitus, Experimental; Endothelin Receptor Antagonists | 1998 |
Streptozotocin diabetes in the pregnant rat induces cardiovascular dysfunction in adult offspring.
Topics: Acetylcholine; Animals; Blood Pressure; Bradykinin; Cardiovascular Diseases; Diabetes Mellitus, Expe | 1999 |
Enhanced, unaltered and impaired nitric oxide-mediated endothelium-dependent relaxation in experimental diabetes mellitus: importance of disease duration.
Topics: Acetylcholine; Animals; Aorta; Diabetes Mellitus, Experimental; Endothelium, Vascular; Enzyme Inhibi | 1999 |
Developmental damage, increased lipid peroxidation, diminished cyclooxygenase-2 gene expression, and lowered prostaglandin E2 levels in rat embryos exposed to a diabetic environment.
Topics: Abnormalities, Drug-Induced; Animals; Congenital Abnormalities; Cyclooxygenase 1; Cyclooxygenase 2; | 1999 |
Microvascular permeability change induced by platelet-activating factor is impaired in diabetic mice.
Topics: Animals; Azo Compounds; Capillary Permeability; Coloring Agents; Cyclooxygenase Inhibitors; Diabetes | 1999 |
Time-course of the alterations in prostanoid production and in contractile responses of mesenteric beds isolated from streptozotocin diabetic rats.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Diabetes Mellitus, Experimental; Dinoprost; Dinoprostone; Ind | 1999 |
Increased activity of H2O2 in aorta isolated from chronically streptozotocin-diabetic rats: effects of antioxidant enzymes and enzymes inhibitors.
Topics: Amitrole; Animals; Antioxidants; Aorta; Catalase; Cyclooxygenase Inhibitors; Diabetes Mellitus, Expe | 1999 |
Biological evaluation of the nitric oxide-trapping agent, N-methyl-D-glucamine dithiocarbamate-Fe2+, as a probe of nitric oxide activity released from control and diabetic rat endothelium.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Blood Glucose; Body Weight; Chelating Agents; Diabetes Mell | 1999 |
Adenosine-induced renal vasoconstriction in diabetes mellitus rats: role of prostaglandins.
Topics: Adenosine; Animals; Cyclooxygenase Inhibitors; Diabetes Mellitus, Experimental; Dinoprostone; Indome | 1999 |
Pharmacological characterization of the cardiovascular responses elicited by kinin B(1) and B(2) receptor agonists in the spinal cord of streptozotocin-diabetic rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bradykinin; Bradykinin Receptor Antagonists; Cardi | 2000 |
Influence of experimental diabetes on regulatory mechanisms of vascular response of rabbit carotid artery to acetylcholine.
Topics: Acetylcholine; Alloxan; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carotid Arteries; Diabetes | 2000 |
COX-2 inhibition prevents insulin-dependent diabetes in low-dose streptozotocin-treated mice.
Topics: Animals; Blood Glucose; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Di | 2000 |
Hyperglycaemia alters the endothelium-dependent relaxation of canine coronary arteries.
Topics: Acetylcholine; Animals; Blood Glucose; Coronary Vessels; Cyclooxygenase Inhibitors; Diabetes Mellitu | 2000 |
Diabetes-induced changes in endothelial mechanisms implicated in rabbit carotid arterial response to 5-hydroxytryptamine.
Topics: Animals; Carotid Arteries; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Endoth | 2000 |
The impaired renal vasodilator response attributed to endothelium-derived hyperpolarizing factor in streptozotocin--induced diabetic rats is restored by 5-methyltetrahydrofolate.
Topics: Acetylcholine; Animals; Biological Factors; Biomarkers; Blood Pressure; Diabetes Mellitus, Experimen | 2000 |
Effects of known and potential antioxidants on animal models of pathological processes (diabetes, gastric lesions, allergic bronchospasm).
Topics: Alloxan; Animals; Antioxidants; Bronchial Spasm; Diabetes Mellitus, Experimental; Disease Models, An | 2000 |
Recovery of microvascular responses during streptozotocin-induced diabetes.
Topics: Acetylcholine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arterioles; Diabetes Mellitus, Expe | 2001 |
Diabetes potentiates acetylcholine-induced relaxation in rabbit renal arteries.
Topics: Acetylcholine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Diabetes Mellitus, Experimental; En | 2001 |
Comparison of effects of diabetes mellitus on an EDHF-dependent and an EDHF-independent artery.
Topics: Acetylcholine; Animals; Biological Factors; Bradykinin; Cardiovascular Agents; Diabetes Mellitus, Ex | 2001 |
Experimental diabetes induces hyperreactivity of rabbit renal artery to 5-hydroxytryptamine.
Topics: Alloxan; Animals; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Drug Synergism; | 2002 |
Elevated spinal cyclooxygenase and prostaglandin release during hyperalgesia in diabetic rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Glucose; Body Weight; Cyclooxygenase 1; Cycl | 2002 |
Altered immune reactivity in encephalomyocarditis-M variant (EMC-M)-induced diabetes in mice.
Topics: Animals; Antilymphocyte Serum; Concanavalin A; Diabetes Mellitus, Experimental; Encephalomyocarditis | 1979 |
Effect of glomerulopressin on ovarian blood flow in dogs.
Topics: Animals; Diabetes Mellitus, Experimental; Dogs; Fasting; Female; Glucuronates; Indomethacin; Ovary; | 1979 |
Disturbed lipid metabolism in diabetic coronary vessels.
Topics: Alloxan; Animals; Arachidonic Acids; Aspirin; Coronary Circulation; Coronary Vessels; Diabetes Melli | 1992 |
Endothelium-dependent relaxation and noradrenaline sensitivity in mesenteric resistance arteries of streptozotocin-induced diabetic rats.
Topics: Acetylcholine; Animals; Arginine; Diabetes Mellitus, Experimental; Endothelium, Vascular; Female; In | 1992 |
The influence of indomethacin and guanethidine on experimental streptozotocin diabetic neuropathy.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Guanethidine; Indomethacin; Male; N | 1992 |
Diabetes mellitus impairs neurogenic and endothelium-dependent relaxation of rabbit corpus cavernosum smooth muscle.
Topics: Acetylcholine; Animals; Diabetes Mellitus, Experimental; Electric Stimulation; Endothelium, Vascular | 1992 |
Endothelium-dependent increase in vascular sensitivity to phenylephrine in long-term streptozotocin diabetic rat aorta.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Diabetes Mellitus, Experimental; Endothelium, Vascular; Ind | 1992 |
A possible role for urinary bladder epithelium in bradykinin-induced contraction in diabetic rats.
Topics: Animals; Bradykinin; Diabetes Mellitus, Experimental; Dinoprost; Dinoprostone; Epithelium; In Vitro | 1992 |
Atrial natriuretic peptide and prostacyclin synergistically mediate hyperfiltration and hyperperfusion of diabetic rats.
Topics: Animals; Atrial Natriuretic Factor; Diabetes Mellitus, Experimental; Drug Synergism; Epoprostenol; G | 1992 |
Effects of prostaglandins and of leukotriene C4 on the metabolism of labelled glucose in uteri isolated from ovariectomized-diabetic rats. Influences of 17-beta-estradiol and of insulin.
Topics: Alprostadil; Animals; Biological Assay; Diabetes Mellitus, Experimental; Dinoprostone; Estradiol; Fe | 1992 |
[Protective effect of indomethacin on alloxan-induced diabetes in rat].
Topics: Alloxan; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Glucagon; Indomethacin; Insulin; I | 1992 |
The effect of aldose reductase inhibition and dietary protein restriction on renal function in experimental diabetes mellitus.
Topics: Aldehyde Reductase; Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Dietary Protei | 1991 |
Attenuated responses to endothelin-1, KCl and CaCl2, but not noradrenaline, of aortae from rats with streptozotocin-induced diabetes mellitus.
Topics: Animals; Aorta, Thoracic; Body Weight; Calcium Chloride; Diabetes Mellitus, Experimental; Electric S | 1991 |
Mechanism of impaired responses of cerebral arterioles during diabetes mellitus.
Topics: Animals; Arginine; Arterioles; Brain; Bridged Bicyclo Compounds, Heterocyclic; Diabetes Mellitus, Ex | 1991 |
Evidence against a role of arachidonic acid metabolites in autoregulatory responses of the isolated perfused kidney of the rat.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic | 1991 |
Superoxide dismutase recovers altered endothelium-dependent relaxation in diabetic rat aorta.
Topics: Animals; Aorta; Diabetes Mellitus, Experimental; Endothelium, Vascular; Free Radical Scavengers; Ind | 1991 |
Increased vasoconstrictor response to noradrenaline in femoral vascular bed of diabetic dogs. Is thromboxane A2 involved?
Topics: Animals; Aspirin; Cyclooxygenase Inhibitors; Diabetes Mellitus, Experimental; Dogs; Dose-Response Re | 1990 |
[Mechanism of action of pronase on chronic proliferative inflammation including granuloma angiogenesis in mice].
Topics: Animals; Collagen; Diabetes Mellitus, Experimental; Granuloma; Hydrocortisone; Hydroxyproline; Indom | 1986 |
Involvement of thromboxane and leukotriene in arachidonate induced coronary constriction in diabetic rats.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Diabetes Mellitus, Experimental; Heart; In Vitro Techn | 1989 |
Prostacyclin and pathogenesis of hemodynamic abnormalities of diabetic ketoacidosis in rats.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Glucose; Blood Pressure; Diabetes Mellitus, Experimenta | 1989 |
Altered microvascular reactivity in streptozotocin-induced diabetes in rats.
Topics: Angiotensin II; Animals; Arteries; Arterioles; Cyclooxygenase Inhibitors; Diabetes Mellitus, Experim | 1989 |
Effects of acute sodium salicylate on the abnormal counterregulatory glucagon and epinephrine responses to insulin hypoglycemia in diabetic rats.
Topics: Animals; Diabetes Mellitus, Experimental; Epinephrine; Glucagon; Hypoglycemia; Indomethacin; Insulin | 1989 |
Hypersensitivity to methoxamine in atria isolated from streptozotocin-induced diabetic rats.
Topics: Adrenergic alpha-Antagonists; Animals; Aspirin; Cyclooxygenase Inhibitors; Diabetes Mellitus, Experi | 1986 |
Gingival tissue-produced inhibition of platelet aggregation and the loss of inhibition in streptozotocin-induced diabetic rats.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Diabetes Mellitus, Experimental; Epoprostenol; Gingiva | 1988 |
Sequential alterations in glomerular prostaglandin and thromboxane synthesis in diabetic rats: relationship to the hyperfiltration of early diabetes.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Blood Glucose; Calcimyci | 1987 |
Oxygen free radicals abolish endothelium-dependent relaxation in diabetic rat aorta.
Topics: Acetylcholine; Adenosine Diphosphate; Animals; Aorta, Thoracic; Ascorbic Acid; Catalase; Diabetes Me | 1988 |
Prostaglandins and altered diabetic vasoregulation.
Topics: Animals; Coronary Vessels; Diabetes Mellitus, Experimental; Dinoprost; Dogs; Female; In Vitro Techni | 1988 |
Effect of diabetes on vascular smooth muscle function in normotensive and spontaneously hypertensive rat mesenteric artery.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Dose-Response Relationship, Dr | 1987 |
Effects of indomethacin on glomerular hemodynamics in experimental diabetes.
Topics: Animals; Body Weight; Capillaries; Diabetes Mellitus, Experimental; Glomerular Filtration Rate; Hemo | 1986 |
Endocrine disorders render rats hyporeactive to non-steroidal but not to steroidal anti-inflammatory drugs.
Topics: Adrenalectomy; Animals; Anti-Inflammatory Agents; Diabetes Mellitus, Experimental; Granulation Tissu | 1985 |
Different effects of prostaglandins E2 and F2 alpha on triglyceride levels in uterine smooth muscle from diabetic diestrous rats.
Topics: Animals; Diabetes Mellitus, Experimental; Diestrus; Dinoprost; Dinoprostone; Estrus; Female; Indomet | 1985 |
Regulation of protein turnover in vivo by insulin and amino acids.
Topics: Amino Acids; Animals; Diabetes Mellitus, Experimental; Eating; Fasting; Indomethacin; Insulin; Kinet | 1985 |
The effects of cyclooxygenase and lipoxygenase inhibitors on the collagen abnormalities of diabetic rats.
Topics: Acetaminophen; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Collagen; Cyclooxygenase Inhib | 1985 |
Effects of prostaglandin E2 and indomethacin on 25-hydroxyvitamin D3-1 alpha-hydroxylase activity in isolated kidney cells of normal and streptozotocin-induced diabetic rats.
Topics: Animals; Calcitriol; Cell Separation; Cholestanetriol 26-Monooxygenase; Diabetes Mellitus, Experimen | 1985 |
Effects of certain nonsteroid anti-inflammatory drugs, tolbutamide, and tetrahydroalstonine on blood glucose and carrageen in-induced pedal edema in rats.
Topics: Alkaloids; Animals; Anti-Inflammatory Agents; Blood Glucose; Carrageenan; Chlorpromazine; Diabetes M | 1972 |