Page last updated: 2024-10-29

indomethacin and Alkalosis

indomethacin has been researched along with Alkalosis in 13 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Alkalosis: A pathological condition that removes acid or adds base to the body fluids.

Research Excerpts

ExcerptRelevanceReference
"Furosemide is one of the most common drug used to treat anasarca in childhood nephrotic syndrome."7.88Furosemide-induced tubular dysfunction responding to prostaglandin synthesis inhibitor therapy in a child with nephrotic syndrome. ( Dawman, L; Santhiya, S; Sharma, A; Tiewsoh, K; Varma, TH, 2018)
"Furosemide is one of the most common drug used to treat anasarca in childhood nephrotic syndrome."3.88Furosemide-induced tubular dysfunction responding to prostaglandin synthesis inhibitor therapy in a child with nephrotic syndrome. ( Dawman, L; Santhiya, S; Sharma, A; Tiewsoh, K; Varma, TH, 2018)
"A four-year-old girl with growth failure and clinical and laboratory evidence of Bartter's syndrome responded to indomethacin treatment with decreased urinary prostaglandin excretion, symptomatic and chemical improvement, and accelerated growth."3.67Reversal of Bartter's syndrome by renal transplantation in a child with focal, segmental glomerular sclerosis. ( Blethen, SL; Jennette, JC; Lorentz, WB; Van Wyk, JJ, 1985)
"Bartter syndrome is a group of rare autosomal-recessive disorders caused by a defect in distal tubule transport of sodium and chloride."1.38Classic Bartter syndrome: a rare cause of failure to thrive in a child. ( da Silva, JE; Mendes, L; Mendes, P; Vieira, H, 2012)
"With early diagnosis and proper treatment, Bartter syndrome has a good prognosis."1.35Bartter syndrome presenting as poor weight gain and abdominal mass in an infant. ( Gilbert-Barness, E; Heffernan, A; Perlman, S; Steffensen, TS, 2008)
"Tetany was easily provoked by hyperventilation, during which serum ionized calcium remained in normal level despite the exacerbation of alkalosis."1.28[Tetany as a sole manifestation in a patient with Bartter's syndrome and a successful treatment with indomethacin]. ( Araki, T; Fujihara, K; Miyoshi, T; Tanaka, K; Yamaguchi, Y, 1990)
"In conclusion, hyperventilation affected the pulmonary circulation by respiratory alkalosis not by mechanical factors and prostaglandins did not mediate its effects."1.27Hyperventilation, alkalosis, prostaglandins, and pulmonary circulation of the newborn. ( Morin, FC, 1986)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19906 (46.15)18.7374
1990's3 (23.08)18.2507
2000's2 (15.38)29.6817
2010's2 (15.38)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Varma, TH1
Sharma, A1
Santhiya, S1
Dawman, L1
Tiewsoh, K1
Onem, Y1
Kucukardali, Y1
Sahan, B1
Atasoyu, EM1
Ipcioğlu, O1
Terekeci, H1
Solmazgul, E1
Top, C1
Oktenli, C1
Heffernan, A1
Steffensen, TS1
Gilbert-Barness, E1
Perlman, S1
Vieira, H1
Mendes, L1
Mendes, P1
da Silva, JE1
Licht, JH1
McVicker, K1
Frazier, LW1
Jones, ER1
Beck, TR1
Kapoor, S1
Shay, R1
Narins, RG1
Mitkov, D1
Bień, B1
Lamnari, AM1
Górska, M1
Fujihara, K1
Miyoshi, T1
Yamaguchi, Y1
Araki, T1
Tanaka, K1
Morin, FC1
Tsuru, N1
Chan, JC1
Blethen, SL1
Van Wyk, JJ1
Lorentz, WB1
Jennette, JC1

Other Studies

13 other studies available for indomethacin and Alkalosis

ArticleYear
Furosemide-induced tubular dysfunction responding to prostaglandin synthesis inhibitor therapy in a child with nephrotic syndrome.
    CEN case reports, 2018, Volume: 7, Issue:2

    Topics: Alkalosis; Bartter Syndrome; Child, Preschool; Cyclooxygenase Inhibitors; Diuretics; Female; Furosem

2018
Analyses of subjects with hypokalemic metabolic alkolosis, Gitelman's and Bartter's syndrome.
    Renal failure, 2008, Volume: 30, Issue:7

    Topics: Adolescent; Adult; Alkalosis; Bartter Syndrome; Follow-Up Studies; Gitelman Syndrome; Humans; Hypoka

2008
Bartter syndrome presenting as poor weight gain and abdominal mass in an infant.
    Fetal and pediatric pathology, 2008, Volume: 27, Issue:4-5

    Topics: Abdomen; Alkalosis; Anti-Inflammatory Agents, Non-Steroidal; Bartter Syndrome; Gitelman Syndrome; Hi

2008
Classic Bartter syndrome: a rare cause of failure to thrive in a child.
    BMJ case reports, 2012, Jun-28, Volume: 2012

    Topics: Alkalosis; Anti-Inflammatory Agents, Non-Steroidal; Bartter Syndrome; Failure to Thrive; Female; Hum

2012
Parathyroid-hormone-induced metabolic alkalosis in dogs.
    Mineral and electrolyte metabolism, 1982, Volume: 8, Issue:2

    Topics: Acid-Base Equilibrium; Alkalosis; Animals; Bicarbonates; Blood; Calcium; Clodronic Acid; Dogs; Femal

1982
The effect of acid-base changes on vasopressin-stimulated water flow in toad urinary bladder.
    Life sciences, 1980, Jun-02, Volume: 26, Issue:22

    Topics: Acid-Base Imbalance; Acidosis; Alkalosis; Animals; Body Water; Bucladesine; Bufo marinus; Drug Inter

1980
Prostaglandins inhibit renal ammoniagenesis in the rat.
    The Journal of clinical investigation, 1984, Volume: 74, Issue:3

    Topics: Acidosis; Alkalosis; Ammonia; Animals; Hydrogen-Ion Concentration; In Vitro Techniques; Indomethacin

1984
Short chain fatty acid-induced hyperventilation is due to PGF2-alpha.
    Prostaglandins, leukotrienes, and essential fatty acids, 1993, Volume: 49, Issue:5

    Topics: Alkalosis; Animals; Carbon Dioxide; Dinoprost; Fatty Acids; Hyperventilation; Hypocapnia; Indomethac

1993
[Hypokalemic metabolic alkalosis with hypomagnesemia and hypocalciuria; Bartter's syndrome in Gitelman's variant--case report].
    Polskie Archiwum Medycyny Wewnetrznej, 1995, Volume: 94, Issue:5

    Topics: Adult; Alkalosis; Bartter Syndrome; Humans; Hypokalemia; Indomethacin; Magnesium; Male; Potassium; P

1995
[Tetany as a sole manifestation in a patient with Bartter's syndrome and a successful treatment with indomethacin].
    Rinsho shinkeigaku = Clinical neurology, 1990, Volume: 30, Issue:5

    Topics: Adult; Alkalosis; Bartter Syndrome; Humans; Hyperaldosteronism; Indomethacin; Male; Tetany

1990
Hyperventilation, alkalosis, prostaglandins, and pulmonary circulation of the newborn.
    Journal of applied physiology (Bethesda, Md. : 1985), 1986, Volume: 61, Issue:6

    Topics: 6-Ketoprostaglandin F1 alpha; Alkalosis; Animals; Animals, Newborn; Blood Pressure; Carbon Dioxide;

1986
Growth failure in children with metabolic alkalosis and with metabolic acidosis.
    Nephron, 1987, Volume: 45, Issue:3

    Topics: Acidosis; Alkalosis; Bartter Syndrome; Child; Child, Preschool; Growth Disorders; Humans; Indomethac

1987
Reversal of Bartter's syndrome by renal transplantation in a child with focal, segmental glomerular sclerosis.
    The American journal of the medical sciences, 1985, Volume: 289, Issue:1

    Topics: Alkalosis; Child, Preschool; Female; Glomerulonephritis; Glomerulosclerosis, Focal Segmental; Humans

1985