indomethacin has been researched along with Alcoholic Intoxication in 4 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Alcoholic Intoxication: An acute brain syndrome which results from the excessive ingestion of ETHANOL or ALCOHOLIC BEVERAGES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Indomethacin pretreatment significantly reduced the mortality rate independent of pretreatment time and produced an increase in the number of animals exhibiting a depressed behavioral response as measured by loss of the righting reflex." | 1.26 | Indomethacin significantly reduces mortality due to acute ethanol overexposure. ( Collins, AC; Elmer, GI; George, FR, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| George, FR | 3 |
| Elmer, GI | 2 |
| Collins, AC | 1 |
| Knych, ET | 1 |
4 other studies available for indomethacin and Alcoholic Intoxication
| Article | Year |
|---|---|
Indomethacin significantly reduces mortality due to acute ethanol overexposure.
Topics: Alcoholic Intoxication; Animals; Body Temperature Regulation; Depression, Chemical; Ethanol; Humans; | 1982 |
Antagonism of ethanol by pretreatment or posttreatment with RO 15-4513 and indomethacin alone or in combination.
Topics: Alcoholic Intoxication; Animals; Azides; Benzodiazepines; Brain; Chloride Channels; Dose-Response Re | 1995 |
The role of arachidonic acid metabolites in mediating ethanol self-administration and intoxication.
Topics: Alcoholic Intoxication; Animals; Arachidonic Acids; Ethanol; Indomethacin; Male; Rats; Rats, Inbred | 1989 |
The role of endothelium in tolerance to ethanol-induced contraction of the rat aorta.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Alcoholic Intoxication; Animals; Aorta; Chromones; Drug Tolerance; | 1987 |