Page last updated: 2024-10-29

indomethacin and Agranulocytosis

indomethacin has been researched along with Agranulocytosis in 16 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Agranulocytosis: A decrease in the number of GRANULOCYTES; (BASOPHILS; EOSINOPHILS; and NEUTROPHILS).

Research Excerpts

ExcerptRelevanceReference
" Illustrative examples from a study of agranulocytosis and indomethacin are presented."3.69Confidence intervals for the excess risk in case-control studies. ( Siskind, V, 1996)
"Drug-induced immune system mediated agranulocytosis is a rare but potentially life-threatening condition."1.29Effective treatment of drug-induced agranulocytosis using recombinant human granulocyte colony stimulating factor in pregnancy. ( Fujiwaki, R; Furuya, H; Hata, K; Hata, T; Katoh, Y; Kitao, M, 1995)
" An overestimation of rare side-effects of drugs should not block the application of certain medicaments, however, they should be given only in such a high dosage as it is necessary."1.26[Hematotoxic lesions caused by non-steroidal antirheumatic agents]. ( Hüge, W; Stobbe, H, 1980)
"Granulocytopenia was found to have no effect."1.26Platelet aggregability in microvascular haemostasis and the effect of local inflammation. ( Arfors, KE; Bergqvist, D, 1978)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199013 (81.25)18.7374
1990's2 (12.50)18.2507
2000's1 (6.25)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Avery, JK1
Alexanian, R1
Gutterman, J1
Levy, H1
Rojas, J1
Stahlman, M1
Bagby, GC1
Gilbert, DN1
Tebbi, CK1
Mahmoud, AA1
Polmar, S1
Gross, S1
Dahinden, C1
Fehr, J1
Stobbe, H1
Hüge, W1
Fujiwaki, R1
Hata, T1
Hata, K1
Kitao, M1
Furuya, H1
Katoh, Y1
Siskind, V1
Schmitt, E1
Arfors, KE1
Bergqvist, D1
Smith, JG1
Smith, MA1
James, I1
Blundell, E1
Maddison, PJ1
Ohishi, M1
Oobu, K1
Miyanoshita, Y1
Yamaguchi, K1
Nelemans, FA1
Müller, WH1
Tanner, E1
Szewczyk, Z1
Kuźniar, J1

Reviews

1 review available for indomethacin and Agranulocytosis

ArticleYear
[Treatment of ankylosing spondylitis].
    Medizinische Klinik, 1979, Sep-07, Volume: 74, Issue:36

    Topics: Agranulocytosis; Anti-Inflammatory Agents; Balneology; Edema; Exercise Therapy; Humans; Indomethacin

1979

Other Studies

15 other studies available for indomethacin and Agranulocytosis

ArticleYear
Loss prevention case of the month. Monitoring remains critical.
    Tennessee medicine : journal of the Tennessee Medical Association, 2004, Volume: 97, Issue:1

    Topics: Acetaminophen; Agranulocytosis; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Clini

2004
Interferon treatment for multiple myeloma.
    Clinics in haematology, 1982, Volume: 11, Issue:1

    Topics: Adult; Aged; Agranulocytosis; Carboxymethylcellulose Sodium; Female; Humans; Indomethacin; Interfero

1982
The effects of group B streptococcus and other organisms on the pulmonary vasculature.
    Clinics in perinatology, 1984, Volume: 11, Issue:3

    Topics: Agranulocytosis; Airway Resistance; Animals; Bacterial Toxins; Capillary Permeability; Endotoxins; E

1984
Suppression of granulopoiesis by T-lymphocytes in two patients with disseminated mycobacterial infection.
    Annals of internal medicine, 1981, Volume: 94, Issue:4 pt 1

    Topics: Adult; Agranulocytosis; Bone Marrow; Cells, Cultured; Female; Hematopoiesis; Humans; Indomethacin; M

1981
The role of eosinophils in granulopoiesis. I. Eosinophilia in neutropenic patients.
    The Journal of pediatrics, 1980, Volume: 96, Issue:3 Pt 2

    Topics: Aged; Agranulocytosis; Bone Marrow; Child; Colony-Forming Units Assay; Eosinophilia; Eosinophils; Fe

1980
Receptor-directed inhibition of chemotactic factor-induced neutrophil hyperactivity by pyrazolon derivatives. Definition of a chemotactic peptide antagonist.
    The Journal of clinical investigation, 1980, Volume: 66, Issue:5

    Topics: Agranulocytosis; Arachidonic Acids; Aspirin; Cell Adhesion; Chemotactic Factors; Chemotaxis, Leukocy

1980
[Hematotoxic lesions caused by non-steroidal antirheumatic agents].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1980, Dec-01, Volume: 35, Issue:23

    Topics: Adult; Aged; Agranulocytosis; Anemia, Aplastic; Arthritis, Rheumatoid; Aspirin; Diclofenac; Female;

1980
Effective treatment of drug-induced agranulocytosis using recombinant human granulocyte colony stimulating factor in pregnancy.
    Gynecologic and obstetric investigation, 1995, Volume: 40, Issue:4

    Topics: Adult; Agranulocytosis; Drug Therapy, Combination; Female; Granulocyte Colony-Stimulating Factor; Hu

1995
Confidence intervals for the excess risk in case-control studies.
    Statistics in medicine, 1996, Jul-30, Volume: 15, Issue:14

    Topics: Age Distribution; Agranulocytosis; Anemia, Aplastic; Bayes Theorem; Case-Control Studies; Confidence

1996
Platelet aggregability in microvascular haemostasis and the effect of local inflammation.
    Haemostasis, 1978, Volume: 7, Issue:1

    Topics: Agranulocytosis; Animals; Female; Hemostasis; Indomethacin; Inflammation; Male; Mesentery; Microcirc

1978
Inhibition of CFU-GM by prostaglandins in a case of chronic T-cell lymphocytosis and neutropenia.
    British journal of haematology, 1989, Volume: 73, Issue:2

    Topics: Agranulocytosis; Cells, Cultured; Chronic Disease; Female; Granulocytes; Hematopoietic Stem Cells; H

1989
Acute gingival necrosis caused by drug-induced agranulocytosis.
    Oral surgery, oral medicine, and oral pathology, 1988, Volume: 66, Issue:2

    Topics: Agranulocytosis; Candidiasis, Oral; Cefmetazole; Dipyrone; Female; Gingivitis; Humans; Indomethacin;

1988
[Analgesics in dentistry].
    Nederlands tijdschrift voor tandheelkunde, 1972, Volume: 79, Issue:2

    Topics: Acetanilides; Agranulocytosis; Analgesics; Anesthesia, Dental; Aspirin; Blood Coagulation; Caffeine;

1972
[Gold therapy and agranulocytosis].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1973, Aug-01, Volume: 28, Issue:15

    Topics: Adult; Agranulocytosis; Aminopyrine; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspir

1973
[A case of agranulocytosis following treatment with Indocid].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1971, Apr-15, Volume: 24, Issue:8

    Topics: Adolescent; Age Factors; Agranulocytosis; Anti-Bacterial Agents; Female; Gingivitis, Necrotizing Ulc

1971