Page last updated: 2024-10-29

indomethacin and Aggressive Periodontitis

indomethacin has been researched along with Aggressive Periodontitis in 1 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Aggressive Periodontitis: Inflammation and loss of PERIODONTIUM that is characterized by rapid attachment loss and bone destruction in the presence of little local factors such as DENTAL PLAQUE and DENTAL CALCULUS. This highly destructive form of periodontitis often occurs in young people and was called early-onset periodontitis, but this disease also appears in old people.

Research Excerpts

ExcerptRelevanceReference
"Patients with localized juvenile periodontitis (LJP) have elevated levels of immunoglobulin G2 (IgG2) in their sera."1.31Regulation of immunoglobulin G2 production by prostaglandin E(2) and platelet-activating factor. ( Barbour, SE; Best, AM; Ishihara, Y; Quinn, SM; Schenkein, HA; Tew, JG; Zhang, JB, 2000)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ishihara, Y1
Zhang, JB1
Quinn, SM1
Schenkein, HA1
Best, AM1
Barbour, SE1
Tew, JG1

Other Studies

1 other study available for indomethacin and Aggressive Periodontitis

ArticleYear
Regulation of immunoglobulin G2 production by prostaglandin E(2) and platelet-activating factor.
    Infection and immunity, 2000, Volume: 68, Issue:3

    Topics: Aggressive Periodontitis; Cells, Cultured; Dinoprostone; Humans; Immunoglobulin G; Indomethacin; Mac

2000