indomethacin has been researched along with Adenoma in 15 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Adenoma: A benign epithelial tumor with a glandular organization.
| Excerpt | Relevance | Reference |
|---|---|---|
| "With indomethacin treatment diurnal rectal fluid production dropped by about 50% and all prostanoids measured in urine and rectal fluid decreased below control values." | 5.28 | Secretory diarrhea in villous adenoma of rectum: effect of treatment with somatostatin and indomethacin. ( Hoekman, K; Keirse, MJ; Meinders, AE; Noort, WA; Smelt, AH, 1992) |
| " After hydroelectrolytic treatment, a PG synthetase inhibitor (indomethacin) was added to a dosage of 25 mg q/d PO." | 5.28 | [Treatment with indomethacin for the control of the metabolic disorder caused by a villous adenoma of the rectum]. ( Batalla Eiras, A; Casal Iglesias, L; Cutrin Prieto, C; Diéguez Gómez, P; Lorenzo Zúniga, V; Meniño Olveira, MJ, 1991) |
| "Treatment with indomethacin, another PES inhibitor, also did not reduce the pulmonary BP metabolite:DNA adduct levels." | 5.27 | Effect of aspirin and indomethacin on the formation of benzo(a)pyrene-induced pulmonary adenomas and DNA adducts in A/HeJ mice. ( Adriaenssens, PI; Anderson, MW; Boorman, GA; Eling, TE; Sivarajah, K, 1983) |
| "Indomethacin treatment (24 mg X 4 daily) reduced the rectal PGE2 excretion from 2." | 5.26 | Prostaglandin E2-mediated secretory diarrhea in villous adenoma of rectum: effect of treatment with indomethacin. ( Bukhave, K; Lange, P; Rask-Madsen, J; Steven, K, 1981) |
| "Low-dose angiotensin II (ANG II) infusion raised plasma atrial natriuretic peptide (ANP) levels only when endogenous renin-angiotensin levels were low, as in aldosterone-producing adenoma." | 3.67 | Atrial natriuretic peptide levels during angiotensin infusion and indomethacin administration are consistent with angiotensin-mediated regulation in man. ( Gordon, RD; Klemm, SA; Tunny, TJ, 1987) |
| "Lung cancer is the leading cause of cancer-related death worldwide." | 1.38 | Non-invasive X-ray micro-computed tomographic evaluation of indomethacin on urethane-induced lung carcinogenesis in mice. ( Hayakawa, T; Imai, T; Imaida, K; Komiya, M; Mutoh, M; Takahashi, M; Tsuta, K; Ueno, T; Wakabayashi, K; Yanaka, A; Yoshimoto, M, 2012) |
| " We demonstrate that a reduction of cyclooxygenase 2 gene dosage rescued the ovarian aging phenotype of the Wv mice, whereas homozygous deletion was accompanied by a compensatory increase in ovarian cyclooxygenase 1 expression and prostaglandin E(2) synthesis." | 1.34 | A reduction of cyclooxygenase 2 gene dosage counters the ovarian morphological aging and tumor phenotype in Wv mice. ( Cai, KQ; Hamilton, TC; Klein-Szanto, A; Smedberg, JL; Smith, ER; Xu, XX; Yang, WL, 2007) |
| "With indomethacin treatment diurnal rectal fluid production dropped by about 50% and all prostanoids measured in urine and rectal fluid decreased below control values." | 1.28 | Secretory diarrhea in villous adenoma of rectum: effect of treatment with somatostatin and indomethacin. ( Hoekman, K; Keirse, MJ; Meinders, AE; Noort, WA; Smelt, AH, 1992) |
| " After hydroelectrolytic treatment, a PG synthetase inhibitor (indomethacin) was added to a dosage of 25 mg q/d PO." | 1.28 | [Treatment with indomethacin for the control of the metabolic disorder caused by a villous adenoma of the rectum]. ( Batalla Eiras, A; Casal Iglesias, L; Cutrin Prieto, C; Diéguez Gómez, P; Lorenzo Zúniga, V; Meniño Olveira, MJ, 1991) |
| "Treatment with indomethacin, another PES inhibitor, also did not reduce the pulmonary BP metabolite:DNA adduct levels." | 1.27 | Effect of aspirin and indomethacin on the formation of benzo(a)pyrene-induced pulmonary adenomas and DNA adducts in A/HeJ mice. ( Adriaenssens, PI; Anderson, MW; Boorman, GA; Eling, TE; Sivarajah, K, 1983) |
| "Indomethacin treatment (24 mg X 4 daily) reduced the rectal PGE2 excretion from 2." | 1.26 | Prostaglandin E2-mediated secretory diarrhea in villous adenoma of rectum: effect of treatment with indomethacin. ( Bukhave, K; Lange, P; Rask-Madsen, J; Steven, K, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (46.67) | 18.7374 |
| 1990's | 5 (33.33) | 18.2507 |
| 2000's | 1 (6.67) | 29.6817 |
| 2010's | 2 (13.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Grangeon, L | 1 |
| Moscatelli, L | 1 |
| Zanin, A | 1 |
| Rouille, A | 1 |
| Maltete, D | 1 |
| Guegan-Massardier, E | 1 |
| Ueno, T | 1 |
| Imaida, K | 1 |
| Yoshimoto, M | 1 |
| Hayakawa, T | 1 |
| Takahashi, M | 2 |
| Imai, T | 1 |
| Yanaka, A | 1 |
| Tsuta, K | 1 |
| Komiya, M | 1 |
| Wakabayashi, K | 1 |
| Mutoh, M | 1 |
| Yang, WL | 1 |
| Cai, KQ | 1 |
| Smedberg, JL | 1 |
| Smith, ER | 1 |
| Klein-Szanto, A | 1 |
| Hamilton, TC | 1 |
| Xu, XX | 1 |
| Adriaenssens, PI | 1 |
| Sivarajah, K | 1 |
| Boorman, GA | 1 |
| Eling, TE | 1 |
| Anderson, MW | 1 |
| Steven, K | 1 |
| Lange, P | 1 |
| Bukhave, K | 2 |
| Rask-Madsen, J | 1 |
| Jones, TH | 1 |
| Kennedy, RL | 1 |
| Justice, SK | 1 |
| Price, A | 1 |
| Sandler, RS | 1 |
| Smelt, AH | 1 |
| Meinders, AE | 1 |
| Hoekman, K | 1 |
| Noort, WA | 1 |
| Keirse, MJ | 1 |
| Cutrin Prieto, C | 1 |
| Casal Iglesias, L | 1 |
| Batalla Eiras, A | 1 |
| Meniño Olveira, MJ | 1 |
| Diéguez Gómez, P | 1 |
| Lorenzo Zúniga, V | 1 |
| Klemm, SA | 1 |
| Tunny, TJ | 1 |
| Gordon, RD | 1 |
| Hagiwara, A | 1 |
| Diwan, BA | 1 |
| Ward, JM | 1 |
| Narisawa, T | 1 |
| Niwa, M | 1 |
| Koyama, H | 1 |
| Kusaka, H | 1 |
| Yamazaki, Y | 1 |
| Nagasawa, O | 1 |
| Kotanagi, H | 1 |
| Koyama, K | 1 |
| Fujii, T | 1 |
| Misumi, S | 1 |
| Takeda, F | 1 |
| Tauchnitz, D | 1 |
| Duck, HJ | 1 |
2 reviews available for indomethacin and Adenoma
| Article | Year |
|---|---|
Aspirin and other nonsteroidal anti-inflammatory agents in the prevention of colorectal cancer.
Topics: Adenocarcinoma; Adenoma; Adenomatous Polyposis Coli; Adult; Animals; Anti-Inflammatory Agents, Non-S | 1996 |
Prostaglandin E2 in intestinal secretion with special reference to methodological problems in vivo and in vitro.
Topics: Adenoma; Animals; Cholera; Colonic Diseases, Functional; Diarrhea; Dinoprostone; Dose-Response Relat | 1992 |
13 other studies available for indomethacin and Adenoma
| Article | Year |
|---|---|
Indomethacin-Responsive Paroxysmal Hemicrania in an Elderly Man: An Unusual Presentation of Pituitary Apoplexy.
Topics: Adenoma; Aged; Cyclooxygenase Inhibitors; Humans; Indomethacin; Male; Paroxysmal Hemicrania; Pituita | 2017 |
Non-invasive X-ray micro-computed tomographic evaluation of indomethacin on urethane-induced lung carcinogenesis in mice.
Topics: Adenocarcinoma; Adenoma; Animals; Antineoplastic Agents; Carcinogens; Humans; Hyperplasia; Immunohis | 2012 |
A reduction of cyclooxygenase 2 gene dosage counters the ovarian morphological aging and tumor phenotype in Wv mice.
Topics: Adenoma; Aging; Animals; Blotting, Western; Celecoxib; Cell Transformation, Neoplastic; Cyclooxygena | 2007 |
Effect of aspirin and indomethacin on the formation of benzo(a)pyrene-induced pulmonary adenomas and DNA adducts in A/HeJ mice.
Topics: Adenoma; Animals; Aspirin; Benzo(a)pyrene; Benzopyrenes; Chromatography, High Pressure Liquid; Cyclo | 1983 |
Prostaglandin E2-mediated secretory diarrhea in villous adenoma of rectum: effect of treatment with indomethacin.
Topics: Adenoma; Diarrhea; Humans; Indomethacin; Male; Middle Aged; Prostaglandins E; Rectal Neoplasms | 1981 |
Interleukin-1 stimulates the release of interleukin-6 from cultured human pituitary adenoma cells.
Topics: Adenoma; Adrenocorticotropic Hormone; Adult; Aged; Dinoprostone; Drug Interactions; Female; Growth H | 1993 |
Secretory diarrhea in villous adenoma of rectum: effect of treatment with somatostatin and indomethacin.
Topics: Adenoma; Aged; Body Fluids; Diarrhea; Electrolytes; Humans; Indomethacin; Male; Octreotide; Prostagl | 1992 |
[Treatment with indomethacin for the control of the metabolic disorder caused by a villous adenoma of the rectum].
Topics: Adenoma; Aged; Diarrhea; Female; Humans; Indomethacin; Rectal Neoplasms; Water-Electrolyte Imbalance | 1991 |
Atrial natriuretic peptide levels during angiotensin infusion and indomethacin administration are consistent with angiotensin-mediated regulation in man.
Topics: Adenoma; Adolescent; Adrenal Cortex Neoplasms; Adult; Aldosterone; Angiotensin II; Atrial Natriureti | 1987 |
Modifying effects of butylated hydroxyanisole, di(2-ethylhexyl)phthalate or indomethacin on mouse hepatocarcinogenesis initiated by N-nitrosodiethylamine.
Topics: Adenoma; Animals; Butylated Hydroxyanisole; Cocarcinogenesis; Diethylhexyl Phthalate; Diethylnitrosa | 1986 |
[Increased mucosal ornithine decarboxylase activity in carcinoma-bearing large bowel and its inhibition by indomethacin].
Topics: Adenocarcinoma; Adenoma; Adult; Aged; Aged, 80 and over; Depression, Chemical; Female; Humans; Indom | 1988 |
Management of polyuria subsequent to pituitary surgery based on the diurnal pattern of urinary excretion.
Topics: Adenoma; Adolescent; Adult; Aged; Circadian Rhythm; Diabetes Insipidus; Female; Humans; Indomethacin | 1985 |
[Psoriatic arthritis and ankylopoietic spondylarthritis].
Topics: Adenoma; Adult; Arthritis; Cyclophosphamide; Diabetes Complications; Diagnosis, Differential; Humans | 1969 |