indomethacin has been researched along with Adenocarcinoma in 120 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Adenocarcinoma: A malignant epithelial tumor with a glandular organization.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the combined effects of indomethacin and oxaliplatin on expressions of epidermal growth factor receptor (EGFR), E-cadherin (E-cad), intercellular adhesion molecule-1 (ICAM-1) and CD44v6 related to lymph node metastasis of human lung cancer cell lines." | 7.83 | Combined effects off indomethacin and oxaliplatin on lymph node metastasis related factors in human lung cancerxenografts in nude mice. ( Chen, G; Chen, YQ; Wang, DC; Xing, D; Zhao, YX, 2016) |
| " We report that both indomethacin and ibuprofen improved body weight and weight of the gastrocnemius muscle in tumor-bearing mice." | 7.72 | Indomethacin and ibuprofen preserve gastrocnemius muscle mass in mice bearing the colon-26 adenocarcinoma. ( Al-Majid, S; Hitt, A; McCarthy, DO; Whitney, P, 2004) |
| " The anti-tumor activity of indomethacin was investigated in CDF1 mice (BALB/c X DBA/2) implanted intraperitoneally with mouse colon adenocarcinoma 26 (5 X 10(5) or 2 X 10(5) cells) in a model study to prevent peritoneal recurrence after surgery for gastrointestinal cancers." | 7.67 | [Prevention of peritoneal carcinomatosis recurrence with a prostaglandin synthesis inhibitor, indomethacin]. ( Koyama, H; Masuda, T; Nagasawa, O; Narisawa, T; Takahashi, M, 1987) |
| "The effect of indomethacin on tumor-infiltrating lymphocytes (TIL) was investigated in a spontaneously developed and weakly immunogenic murine mammary adenocarcinoma (designated JC) in syngeneic immunocompetent BALB/c mice, a tumor model mimicking human disease." | 7.67 | Effect of indomethacin on tumor-infiltrating lymphocytes of a spontaneously developed murine mammary adenocarcinoma. ( Chao, TY; Chu, TM, 1989) |
| "The anti-inflammatory drug indomethacin was tested for antitumor activity against transplantable mouse colon adenocarcinoma 38 (colon 38)." | 7.66 | Growth inhibition of transplantable murine colon adenocarcinoma 38 by indomethacin. ( Goto, A; Narisawa, T; Sano, M; Sato, M; Takahashi, T, 1983) |
| " Low-dose indomethacin combined with methylprednisolone may be a new choice for AFOP treatment." | 6.53 | Methylprednisolone combined with low-dose indomethacin treating acute fibrinous and organizing pneumonia after a surgical resection of rectal adenocarcinoma: a case report and literature review. ( Bian, LJ; Chen, M; Chen, QK; Huang, LJ; Jiang, SP; Lin, XL; Tang, TT; Zhou, CX, 2016) |
| "Indomethacin was able to further inhibit the PG formation in a concentration-dependent manner under hypoxia." | 5.28 | Modulation of prostaglandin biosynthesis in hypoxic murine mammary adenocarcinoma cells by misonidazole. ( Agrawal, KC; McNamara, DB; Shalinsky, DR, 1989) |
| "The hypercalcemia was unresponsive to hydration and oral phosphate." | 5.25 | Indomethacin-responsive hypercalcemia in a patient with renal-cell adenocarcinoma. ( Alexander, RW; Brereton, HD; DeVita, VT; Halushka, PV; Keiser, HR; Mason, DM, 1974) |
| " Flurbiprofen, indomethacin and other NSAIDs stimulated 15-PGDH activity in colon cancer HT29 cells as well as in lung cancer A549 cells and glioblastoma T98G cells." | 4.87 | Regulation of 15-hydroxyprostaglandin dehydrogenase (15-PGDH) by non-steroidal anti-inflammatory drugs (NSAIDs). ( Chi, X; Tai, HH; Tong, M, 2011) |
| " pylori infection, indomethacin and their combination affects the healing of gastric ulcers and whether or not such factors provoke a relapse of healed acetic acid ulcers; and 2) whether or not eradication of the bacteria with drugs at specified times after infection prevents the development of mucosal changes, including gastric adenocarcinoma." | 4.81 | [Pharmacological study on the pathological changes of the gastric mucosa in Helicobacter pylori-infected Mongolian gerbils]. ( Ebata, M; Keto, Y; Okabe, S, 2001) |
| "To investigate the combined effects of indomethacin and oxaliplatin on expressions of epidermal growth factor receptor (EGFR), E-cadherin (E-cad), intercellular adhesion molecule-1 (ICAM-1) and CD44v6 related to lymph node metastasis of human lung cancer cell lines." | 3.83 | Combined effects off indomethacin and oxaliplatin on lymph node metastasis related factors in human lung cancerxenografts in nude mice. ( Chen, G; Chen, YQ; Wang, DC; Xing, D; Zhao, YX, 2016) |
| "In this rat model of gastrointestinal reflux, indomethacin was associated with a decrease in the severity of esophagitis and reduced development of esophageal intestinal metaplasia and adenocarcinoma." | 3.78 | Indomethacin but not a selective cyclooxygenase-2 inhibitor inhibits esophageal adenocarcinogenesis in rats. ( Cebrián, C; Escartín, A; Esquivias, P; Esteva, F; García-González, MA; Lanas, A; Morandeira, A; Ortego, J; Piazuelo, E; Santander, S, 2012) |
| " We recently showed that NSAIDs such as indomethacin and celecoxib have direct cytotoxicity (ability to induce necrosis and apoptosis in gastric mucosal cells) due to their membrane permeabilizing activities, which is involved in NSAID-induced gastric lesions." | 3.76 | Low direct cytotoxicity of loxoprofen on gastric mucosal cells. ( Arai, Y; Ishihara, T; Kimoto, A; Mizushima, T; Okamoto, Y; Otsuka, M; Suemasu, S; Tanaka, K; Yamakawa, N; Yokomizo, K, 2010) |
| "To assess the putative involvement of NF-kappaB and pro-inflammatory cytokines in the pathogenesis of cancer cachexia and the therapeutic efficacy of indomethacin (IND) on cachexia." | 3.72 | Role of NF-kappaB and cytokine in experimental cancer cachexia. ( Jiang, J; Jiang, ZW; Li, JS; Li, N; Tian, J; Zhou, W, 2003) |
| " In our study, the effects of TNF-alpha, inhibitors of arachidonic acid (AA) metabolism (baicalein, BA; indomethacin, INDO; niflumic acid, NA; nordihydroguaiaretic acid, NDGA), and/or their combinations on undifferentiated or sodium butyrate (NaBt)-differentiated human colon adenocarcinoma HT-29 cells were compared." | 3.72 | The effects of TNF-alpha and inhibitors of arachidonic acid metabolism on human colon HT-29 cells depend on differentiation status. ( Hofmanová, J; Kovaríková, M; Kozubík, A; Soucek, K, 2004) |
| " We report that both indomethacin and ibuprofen improved body weight and weight of the gastrocnemius muscle in tumor-bearing mice." | 3.72 | Indomethacin and ibuprofen preserve gastrocnemius muscle mass in mice bearing the colon-26 adenocarcinoma. ( Al-Majid, S; Hitt, A; McCarthy, DO; Whitney, P, 2004) |
| "To assess the putative involvement of NF-kappaB and pro-inflammatory cytokines in the pathogenesis of cancer cachexia and the therapeutic efficacy of indomethacin (IND) on cachexia." | 3.72 | [Role of NF-kappa B in cancer cachexia]. ( Jiang, J; Jiang, ZW; Li, JS; Li, N; Zhou, W, 2004) |
| " Here we characterized the effects of non-selective (indomethacin) and selective (NS398, celecoxib) cyclooxygenase inhibitors on parameters of angiogenesis in human pancreatic adenocarcinoma cells." | 3.72 | Celecoxib inhibits angiogenesis by inducing endothelial cell apoptosis in human pancreatic tumor xenografts. ( Davis, DW; Ellis, LM; Khanbolooki, S; Lashinger, LM; McConkey, DJ; Nawrocki, S; Raut, CP; Xiong, H, 2004) |
| " In this paper, we present the effect of indomethacin on growth inhibition and alterations in the expression of several genes involved in cell cycle and apoptosis in CaCo-2 colon adenocarcinoma cells." | 3.71 | Effect of the nonsteroidal anti-inflammatory drug indomethacin on proliferation and apoptosis of colon carcinoma cells. ( Kapitanović, S; Kovacević, D; Kralj, M; Lukac, J; Pavelić, K; Spaventi, S, 2001) |
| "To investigate the relationship between cytokine IL-6, IL-1, TNF-alpha and experimental cancer cachexia as well as observe the effect of indomethacin on the cachectic mice." | 3.71 | [Cytokines in experimental cancer cachexia]. ( Li, T; Liu, A; Niu, Q, 2001) |
| "The clonogenic hybrid spheroid assay has been used to determine the toxicity of 5-fluorouracil (5-FU), alone or in combination with indomethacin, in LoVo cells (a human colon adenocarcinoma line)." | 3.70 | Clonogenic inactivation of colon cancer-derived cells treated with 5-fluorouracil and indomethacin in hybrid spheroids. ( Djordjevic, B; Lange, CS; Rotman, M; Schwartz, MS, 1998) |
| " We evaluated the effect of aspirin (ASA) and three other structurally unrelated NSAIDs (indomethacin, naproxen, and piroxicam) on cell proliferation, cell cycle phase distribution, and the development of apoptosis in HT-29 colon adenocarcinoma cells in vitro." | 3.69 | Nonsteroidal antiinflammatory drugs inhibit the proliferation of colon adenocarcinoma cells: effects on cell cycle and apoptosis. ( Koutsos, MI; Qiao, L; Rigas, B; Shiff, SJ, 1996) |
| "The effect of the polyunsaturated fatty acids (PUFAs) linoleic acid (LA) and arachidonic acid (AA) on the growth of two murine colon adenocarcinoma cell lines (MAC26 and MAC13) has been determined both in vitro and in vivo." | 3.69 | Effect of polyunsaturated fatty acids on the growth of murine colon adenocarcinomas in vitro and in vivo. ( Hussey, HJ; Tisdale, MJ, 1994) |
| "The effect of the inflammatory mediator bradykinin on glycoprotein synthesis and mucin secretion in the human colonic adenocarcinoma cell line HT29-18N2 was examined." | 3.69 | Bradykinin modulates mucin secretion but not synthesis from an intestinal goblet cell line. ( Phillips, TE; Stanley, CM, 1994) |
| "To explore an anti-tumor effect of indomethacin on human colon adenocarcinoma cell line HCT116, and its mechanism." | 3.69 | [Neoplasm-inhibiting effect and sensitivity-promoting effect of indomethacin in vitro]. ( Duan, C; Leng, A; Shi, J; Zhang, G, 1997) |
| "The effect of indomethacin on tumor-infiltrating lymphocytes (TIL) was investigated in a spontaneously developed and weakly immunogenic murine mammary adenocarcinoma (designated JC) in syngeneic immunocompetent BALB/c mice, a tumor model mimicking human disease." | 3.67 | Effect of indomethacin on tumor-infiltrating lymphocytes of a spontaneously developed murine mammary adenocarcinoma. ( Chao, TY; Chu, TM, 1989) |
| "The antitumor activity of indomethacin (IND) was investigated in mice bearing advanced colon 26 adenocarcinoma compared with its early transplants." | 3.67 | Antitumor activity of indomethacin in mice bearing advanced colon 26 carcinoma compared with those with early transplants. ( Ishitsuka, H; Tanaka, T; Tanaka, Y, 1989) |
| " The anti-tumor activity of indomethacin was investigated in CDF1 mice (BALB/c X DBA/2) implanted intraperitoneally with mouse colon adenocarcinoma 26 (5 X 10(5) or 2 X 10(5) cells) in a model study to prevent peritoneal recurrence after surgery for gastrointestinal cancers." | 3.67 | [Prevention of peritoneal carcinomatosis recurrence with a prostaglandin synthesis inhibitor, indomethacin]. ( Koyama, H; Masuda, T; Nagasawa, O; Narisawa, T; Takahashi, M, 1987) |
| "The anti-inflammatory drug indomethacin was tested for antitumor activity against transplantable mouse colon adenocarcinoma 38 (colon 38)." | 3.66 | Growth inhibition of transplantable murine colon adenocarcinoma 38 by indomethacin. ( Goto, A; Narisawa, T; Sano, M; Sato, M; Takahashi, T, 1983) |
| " Low-dose indomethacin combined with methylprednisolone may be a new choice for AFOP treatment." | 2.53 | Methylprednisolone combined with low-dose indomethacin treating acute fibrinous and organizing pneumonia after a surgical resection of rectal adenocarcinoma: a case report and literature review. ( Bian, LJ; Chen, M; Chen, QK; Huang, LJ; Jiang, SP; Lin, XL; Tang, TT; Zhou, CX, 2016) |
| "Lung cancer is the leading cause of cancer-related death worldwide." | 1.38 | Non-invasive X-ray micro-computed tomographic evaluation of indomethacin on urethane-induced lung carcinogenesis in mice. ( Hayakawa, T; Imai, T; Imaida, K; Komiya, M; Mutoh, M; Takahashi, M; Tsuta, K; Ueno, T; Wakabayashi, K; Yanaka, A; Yoshimoto, M, 2012) |
| "Treatment with parecoxib, higher dose or indomethacin significantly inhibited tumor growth." | 1.38 | Cyclooxygenase inhibitors decrease the growth and induce regression of human esophageal adenocarcinoma xenografts in nude mice. ( Cebrián, C; Conde, B; Esquivias, P; Esteva, F; Jiménez, P; Lanas, A; Ortego, J; Piazuelo, E; Santander, S, 2012) |
| "(4) Induction of apoptosis in colon cancer cells by NSAIDs may explain in part, their inhibitory action on colon cancer growth." | 1.33 | Identification of specific genes and pathways involved in NSAIDs-induced apoptosis of human colon cancer cells. ( Chai, J; Huang, RH; Tarnawski, AS, 2006) |
| "To investigate the role of COX-2 in pancreatic cancer, we evaluated COX-2 protein expression in primary human pancreatic adenocarcinomas (n = 23) and matched normal adjacent tissue (n = 11) by immunoblot analysis." | 1.31 | Cyclooxygenase-2 expression in human pancreatic adenocarcinomas. ( Barnard, DS; Billings, SD; Cheng, L; Crowell, PL; Heilman, DK; Lin, A; Marshall, MS; Marshall, SJ; Sweeney, CJ; Yip-Schneider, MT, 2000) |
| "Indomethacin pretreatment significantly reduced EGF-induced ODC activation and was completely abolished for the first 5 h." | 1.30 | Indomethacin interferes with EGF-induced activation of ornithine decarboxylase in gastric cancer cells. ( Arakawa, T; Fujiwara, Y; Fukuda, T; Ichikawa, Y; Ishikawa, T; Mitsuhashi, M; Shimada, H; Tarnawski, A, 1998) |
| "Pretreatment with indomethacin had no effect on tumor take or initial growth." | 1.30 | The influence of zymosan and indomethacin on liver and kidney tumor growth. An experimental study in rats. ( Blind, PJ; Hafström, LR; Holmberg, SB; Lindnér, PG; Naredi, PL; Ohman, MG, 1997) |
| "tumor growth, secondary lung metastasis and splenocyte cytotoxicity against YAC-1 lymphoma cells (51Cr release assay)." | 1.29 | Effects of histamine type-2 receptor antagonists on indomethacin and IL-2 immunotherapy of metastasis. ( Khoo, NK; Lala, PK; Saarloos, MN, 1993) |
| "The present report demonstrates that colon cancer cells of human (HT-29) and mouse (MCA-38) origin markedly inhibit the generation of activated killer cells in murine spleen cell cultures." | 1.29 | Colon adenocarcinoma cells inhibit anti-CD3-activated killer cell induction. ( Blay, J; Hoskin, DW; Reynolds, T, 1994) |
| "Concerning the effect of rTNF on metastasis, we found that the metastasis to lung was promoted by 1 x 10(5) units of rTNF and the promotion of metastasis was restricted by indomethacin." | 1.29 | Promotion of metastases by tumor necrosis factor in rats bearing Dunning R3327 MAT-LyLu prostatic cancer. ( Iizumi, T; Soma, GI; Umeda, T; Yazaki, T, 1993) |
| "Pretreatment with indomethacin had no significant effect on tumour take or initial growth." | 1.29 | Influence of zymosan (a non-specific macrophage stimulator) and of indomethacin on liver tumours--an experimental study in rats. ( Daneryd, PL; Hafström, LR; Holmberg, SB; Karlberg, IH; Karlsson, LM; Lindnér, GO; Naredi, PL; Pettersson, A; Stenram, U, 1995) |
| "Indomethacin was able to further inhibit the PG formation in a concentration-dependent manner under hypoxia." | 1.28 | Modulation of prostaglandin biosynthesis in hypoxic murine mammary adenocarcinoma cells by misonidazole. ( Agrawal, KC; McNamara, DB; Shalinsky, DR, 1989) |
| " They showed intolerance to Indo at a dosage of 14 micrograms/ml, which was well tolerated by other mouse strains in previous studies, but tolerated the Ibu dosages used." | 1.28 | Immunotherapy of mammary adenocarcinoma metastases in C3H/HeN mice with chronic administration of cyclo-oxygenase inhibitors alone or in combination with IL-2. ( Chan, FP; Khoo, NK; Lala, PK; Saarloos, MN, 1992) |
| " The coculture of indomethacin with interleukin-2 (IL-2) augmented LAK cell activity in an indomethacin dose-response manner, and diminished PGE2 content in the corresponding culture supernatant in a reverse dose-response manner." | 1.28 | Prostaglandin E2 from macrophages of murine splenocyte cultures inhibits the generation of lymphokine-activated killer cell activity. ( Chu, TM; Lin, TH; Nakajima, I; Ohnishi, H, 1991) |
| "Indomethacin was given orally to 40 of the rats." | 1.28 | Effect of indomethacin in autotransplanted colonic tumors. ( Duvander, A; Rubio, CA; Sveander, M; Wallin, B; Ware, J, 1989) |
| "Tumor volume, metastasis, and determination of regression of primary tumor have been evaluated." | 1.27 | Nb rat prostate adenocarcinoma model androgen-sensitive tumor: metastasis control. ( Drago, JR; Fralisch, A; Weed, P, 1983) |
| " The most prominent toxic feature was hemorrhagic colitis which could be alleviated when rMuTNF was preceded by i." | 1.27 | Anti-tumor activity of recombinant mouse tumor necrosis factor (TNF) on colon cancer in rats is promoted by recombinant rat interferon gamma; toxicity is reduced by indomethacin. ( De Bruin, RW; Fiers, W; Ijzermans, JN; Jeekel, J; Marquet, RL, 1987) |
| "In addition, spontaneous metastasis of two highly metastatic tumors was partially inhibited by p." | 1.27 | Relationships of prostaglandin E and natural killer sensitivity to metastatic potential in murine mammary adenocarcinomas. ( Fulton, AM; Heppner, GH, 1985) |
| " Flurbiprofen did not seem to alter the bioavailability of the chemotherapeutic agents." | 1.26 | Increased survival of cancer-bearing mice treated with inhibitors of prostaglandin synthesis alone or with chemotherapy. ( Bennett, A; Berstock, DA; Carroll, MA, 1982) |
| " However, the 10-week cessation of treatment following this effective dosage led to a rapid development of tumors." | 1.26 | Inhibition of development of methylnitrosourea-induced rat colon tumors by indomethacin treatment. ( Goto, A; Kudo, T; Narisawa, T; Sato, M; Takahashi, T; Tani, M, 1981) |
| "The hypercalcemia was unresponsive to hydration and oral phosphate." | 1.25 | Indomethacin-responsive hypercalcemia in a patient with renal-cell adenocarcinoma. ( Alexander, RW; Brereton, HD; DeVita, VT; Halushka, PV; Keiser, HR; Mason, DM, 1974) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 36 (30.00) | 18.7374 |
| 1990's | 40 (33.33) | 18.2507 |
| 2000's | 32 (26.67) | 29.6817 |
| 2010's | 11 (9.17) | 24.3611 |
| 2020's | 1 (0.83) | 2.80 |
| Authors | Studies |
|---|---|
| Castillo-Rodríguez, IO | 1 |
| Pedro-Hernandez, LD | 1 |
| Ramírez-Ápan, T | 1 |
| Martínez-García, M | 1 |
| Xing, D | 1 |
| Chen, YQ | 1 |
| Wang, DC | 1 |
| Zhao, YX | 1 |
| Chen, G | 2 |
| Vallecillo-Hernández, J | 1 |
| Barrachina, MD | 1 |
| Ortiz-Masiá, D | 1 |
| Coll, S | 1 |
| Esplugues, JV | 1 |
| Calatayud, S | 1 |
| Hernández, C | 1 |
| Zhou, CX | 1 |
| Tang, TT | 1 |
| Huang, LJ | 1 |
| Lin, XL | 1 |
| Chen, M | 1 |
| Bian, LJ | 1 |
| Chen, QK | 1 |
| Jiang, SP | 1 |
| Naor, R | 1 |
| Domankevich, V | 1 |
| Shemer, S | 1 |
| Sominsky, L | 1 |
| Rosenne, E | 3 |
| Levi, B | 1 |
| Ben-Eliyahu, S | 3 |
| Yamakawa, N | 1 |
| Suemasu, S | 1 |
| Kimoto, A | 1 |
| Arai, Y | 1 |
| Ishihara, T | 1 |
| Yokomizo, K | 1 |
| Okamoto, Y | 1 |
| Otsuka, M | 1 |
| Tanaka, K | 1 |
| Mizushima, T | 1 |
| Robbins, MS | 1 |
| Grosberg, BM | 1 |
| Chen, SZ | 1 |
| Qiu, ZG | 1 |
| Tai, HH | 1 |
| Chi, X | 1 |
| Tong, M | 1 |
| Santander, S | 2 |
| Cebrián, C | 2 |
| Esquivias, P | 2 |
| Conde, B | 1 |
| Esteva, F | 2 |
| Jiménez, P | 1 |
| Ortego, J | 2 |
| Lanas, A | 2 |
| Piazuelo, E | 2 |
| Zhang, MZ | 1 |
| Morandeira, A | 1 |
| Escartín, A | 1 |
| García-González, MA | 1 |
| Ueno, T | 1 |
| Imaida, K | 1 |
| Yoshimoto, M | 1 |
| Hayakawa, T | 1 |
| Takahashi, M | 3 |
| Imai, T | 1 |
| Yanaka, A | 1 |
| Tsuta, K | 1 |
| Komiya, M | 1 |
| Wakabayashi, K | 1 |
| Mutoh, M | 1 |
| Eross, EJ | 1 |
| Swanson, JW | 1 |
| Dodick, DW | 1 |
| Kudryavtsev, IA | 1 |
| Golenko, OD | 1 |
| Gudkova, MV | 1 |
| Myasishcheva, NV | 1 |
| Nithipatikom, K | 1 |
| Isbell, MA | 1 |
| Lindholm, PF | 1 |
| Kajdacsy-Balla, A | 1 |
| Kaul, S | 1 |
| Campell, WB | 1 |
| Bustuoabad, OD | 1 |
| di Gianni, PD | 1 |
| Franco, M | 1 |
| Kordon, EC | 1 |
| Vanzulli, SI | 1 |
| Meiss, RP | 1 |
| Grion, LC | 1 |
| Díaz, GS | 1 |
| Nosetto, SH | 1 |
| Hockl, P | 1 |
| Lombardi, MG | 1 |
| Pasqualini, CD | 1 |
| Ruggiero, RA | 1 |
| Yakar, I | 1 |
| Melamed, R | 2 |
| Shakhar, G | 1 |
| Shakhar, K | 2 |
| Abudarham, N | 2 |
| Page, GG | 1 |
| Zhou, W | 2 |
| Jiang, ZW | 2 |
| Tian, J | 1 |
| Jiang, J | 2 |
| Li, N | 2 |
| Li, JS | 2 |
| Kovaríková, M | 1 |
| Hofmanová, J | 1 |
| Soucek, K | 1 |
| Kozubík, A | 1 |
| Gibbs, JP | 1 |
| Adeyeye, MC | 1 |
| Yang, Z | 1 |
| Shen, DD | 1 |
| Pozzi, A | 1 |
| Yan, X | 1 |
| Macias-Perez, I | 1 |
| Wei, S | 1 |
| Hata, AN | 1 |
| Breyer, RM | 1 |
| Morrow, JD | 1 |
| Capdevila, JH | 1 |
| McCarthy, DO | 2 |
| Whitney, P | 1 |
| Hitt, A | 2 |
| Al-Majid, S | 1 |
| Peluffo, GD | 2 |
| Stillitani, I | 2 |
| Rodríguez, VA | 1 |
| Diament, MJ | 2 |
| Klein, SM | 2 |
| Raut, CP | 1 |
| Nawrocki, S | 1 |
| Lashinger, LM | 1 |
| Davis, DW | 1 |
| Khanbolooki, S | 1 |
| Xiong, H | 1 |
| Ellis, LM | 1 |
| McConkey, DJ | 1 |
| Yu, J | 1 |
| Tang, BD | 1 |
| Leung, WK | 1 |
| To, KF | 1 |
| Bai, AH | 1 |
| Zeng, ZR | 1 |
| Ma, PK | 1 |
| Go, MY | 1 |
| Hu, PJ | 1 |
| Sung, JJ | 1 |
| Graves, E | 1 |
| Schwartz, Y | 1 |
| Moon, Y | 1 |
| Bottone, FG | 1 |
| McEntee, MF | 1 |
| Eling, TE | 1 |
| He, H | 1 |
| Xia, HH | 1 |
| Wang, JD | 1 |
| Gu, Q | 1 |
| Lin, MC | 1 |
| Zou, B | 1 |
| Lam, SK | 1 |
| Chan, AO | 1 |
| Yuen, MF | 1 |
| Kung, HF | 1 |
| Wong, BC | 1 |
| Cerchietti, LC | 1 |
| Navigante, A | 1 |
| Ranuncolo, SM | 1 |
| Huang, RH | 1 |
| Chai, J | 1 |
| Tarnawski, AS | 2 |
| Lönnroth, C | 1 |
| Andersson, M | 1 |
| Arvidsson, A | 1 |
| Nordgren, S | 1 |
| Brevinge, H | 1 |
| Lagerstedt, K | 1 |
| Lundholm, K | 1 |
| Romeu, J | 1 |
| Chadha, N | 1 |
| Fukilman, O | 1 |
| Dave, P | 1 |
| Lee, M | 1 |
| Braun, DP | 1 |
| Harris, ZL | 1 |
| Harris, JE | 1 |
| Sandler, S | 1 |
| Khandekar, J | 1 |
| Locker, G | 1 |
| Haid, M | 1 |
| Gordon, L | 1 |
| Shaw, J | 1 |
| Cobleigh, M | 1 |
| Narisawa, T | 6 |
| Satoh, M | 1 |
| Sano, M | 2 |
| Takahashi, T | 3 |
| Sato, M | 2 |
| Goto, A | 2 |
| Drago, JR | 2 |
| Weed, P | 1 |
| Fralisch, A | 1 |
| Bennett, A | 1 |
| Berstock, DA | 1 |
| Carroll, MA | 1 |
| Kudo, T | 2 |
| Abo, S | 1 |
| Warshaw, AL | 1 |
| Carey, RW | 1 |
| Robinson, DR | 1 |
| Tani, M | 1 |
| Holmberg, SB | 2 |
| Naredi, PL | 2 |
| Lindnér, GO | 1 |
| Karlberg, IH | 1 |
| Daneryd, PL | 1 |
| Karlsson, LM | 1 |
| Pettersson, A | 1 |
| Stenram, U | 1 |
| Hafström, LR | 2 |
| Iunker, VM | 1 |
| Smirnova, NP | 1 |
| Ustinov, AS | 1 |
| Kudriavtsev, IA | 2 |
| Miasishcheva, NV | 2 |
| Reid, J | 1 |
| Schrader, AP | 1 |
| Morris, BJ | 1 |
| Stanley, CM | 1 |
| Phillips, TE | 1 |
| Hussey, HJ | 1 |
| Tisdale, MJ | 2 |
| Saarloos, MN | 2 |
| Khoo, NK | 2 |
| Lala, PK | 3 |
| Hoskin, DW | 2 |
| Reynolds, T | 1 |
| Blay, J | 1 |
| Smith, KL | 1 |
| Iizumi, T | 1 |
| Yazaki, T | 1 |
| Umeda, T | 1 |
| Soma, GI | 1 |
| Parhar, RS | 1 |
| Shiff, SJ | 1 |
| Koutsos, MI | 1 |
| Qiao, L | 1 |
| Rigas, B | 1 |
| Sandler, RS | 1 |
| Makrigiannakis, A | 1 |
| Zoumakis, E | 1 |
| Margioris, AN | 1 |
| Stournaras, C | 1 |
| Chrousos, GP | 1 |
| Gravanis, A | 1 |
| Kobayashi, S | 1 |
| Okada, S | 1 |
| Yoshida, H | 2 |
| Fujimura, S | 1 |
| Yang, CY | 1 |
| Meng, CL | 1 |
| Shen, KL | 1 |
| Wong, PY | 1 |
| Lee, HK | 1 |
| Ohman, MG | 1 |
| Blind, PJ | 1 |
| Lindnér, PG | 1 |
| Ishikawa, T | 1 |
| Ichikawa, Y | 1 |
| Tarnawski, A | 1 |
| Fujiwara, Y | 1 |
| Fukuda, T | 1 |
| Arakawa, T | 1 |
| Mitsuhashi, M | 1 |
| Shimada, H | 1 |
| Sawaoka, H | 1 |
| Kawano, S | 1 |
| Tsuji, S | 1 |
| Tsujii, M | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Impact of Perioperative Dexmedetomidine on Long-term Survival in Older Patients After Cancer Surgery: a Multicenter Randomized Trial[NCT06030804] | 4,532 participants (Anticipated) | Interventional | 2023-09-12 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for indomethacin and Adenocarcinoma
| Article | Year |
|---|---|
Methylprednisolone combined with low-dose indomethacin treating acute fibrinous and organizing pneumonia after a surgical resection of rectal adenocarcinoma: a case report and literature review.
Topics: Adenocarcinoma; Anti-Inflammatory Agents; Cross Infection; Female; Humans; Indomethacin; Methylpredn | 2016 |
Regulation of 15-hydroxyprostaglandin dehydrogenase (15-PGDH) by non-steroidal anti-inflammatory drugs (NSAIDs).
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line, | 2011 |
Aspirin and other nonsteroidal anti-inflammatory agents in the prevention of colorectal cancer.
Topics: Adenocarcinoma; Adenoma; Adenomatous Polyposis Coli; Adult; Animals; Anti-Inflammatory Agents, Non-S | 1996 |
[Pharmacological study on the pathological changes of the gastric mucosa in Helicobacter pylori-infected Mongolian gerbils].
Topics: Adenocarcinoma; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer | 2001 |
Prostaglandins and hypercalcemic states.
Topics: Adenocarcinoma; Animals; Bone and Bones; Bone Resorption; Humans; Hypercalcemia; Indomethacin; Kidne | 1978 |
1 trial available for indomethacin and Adenocarcinoma
| Article | Year |
|---|---|
Preoperative treatment with a non-steroidal anti-inflammatory drug (NSAID) increases tumor tissue infiltration of seemingly activated immune cells in colorectal cancer.
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cell Mo | 2008 |
114 other studies available for indomethacin and Adenocarcinoma
| Article | Year |
|---|---|
Anticancer Activity of 3,5-Bis(dodecyloxy)Benzoate-PAMAM Conjugates with Indomethacin or Mefenamic Acid.
Topics: Adenocarcinoma; Antineoplastic Agents; Benzoates; Cell Line, Tumor; Humans; Indomethacin; Mefenamic | 2023 |
Combined effects off indomethacin and oxaliplatin on lymph node metastasis related factors in human lung cancerxenografts in nude mice.
Topics: A549 Cells; Adenocarcinoma; Adenocarcinoma of Lung; Animals; Antigens, CD; Antineoplastic Combined C | 2016 |
Indomethacin Disrupts Autophagic Flux by Inducing Lysosomal Dysfunction in Gastric Cancer Cells and Increases Their Sensitivity to Cytotoxic Drugs.
Topics: Adenocarcinoma; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents | 2018 |
Metastatic-promoting effects of LPS: sexual dimorphism and mediation by catecholamines and prostaglandins.
Topics: Adenocarcinoma; Adrenergic beta-Antagonists; Animals; Catecholamines; Cell Line, Tumor; Corticostero | 2009 |
Low direct cytotoxicity of loxoprofen on gastric mucosal cells.
Topics: Adenocarcinoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Apoptosis; | 2010 |
Hemicrania continua-like headache from metastatic lung cancer.
Topics: Adenocarcinoma; Brain Neoplasms; Female; Headache; Humans; Indomethacin; Lung Neoplasms; Magnetic Re | 2010 |
Combined treatment with GH, insulin, and indomethacin alleviates cancer cachexia in a mouse model.
Topics: Adenocarcinoma; Animals; Biomarkers; Body Weight; Cachexia; Colonic Neoplasms; Cytokines; Drug Combi | 2011 |
Cyclooxygenase inhibitors decrease the growth and induce regression of human esophageal adenocarcinoma xenografts in nude mice.
Topics: Adenocarcinoma; Aged; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cyclooxy | 2012 |
[A study on the effects of indomethacin and oxaliplatin on lymphangiogenesis in a nude mice model of transplantation with A549 human lung cancer].
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Antineoplastic Combined Chemotherapy Protocols; Cel | 2012 |
Indomethacin but not a selective cyclooxygenase-2 inhibitor inhibits esophageal adenocarcinogenesis in rats.
Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Barrett Esophagus; Cell Transformation, Neoplastic | 2012 |
Non-invasive X-ray micro-computed tomographic evaluation of indomethacin on urethane-induced lung carcinogenesis in mice.
Topics: Adenocarcinoma; Adenoma; Animals; Antineoplastic Agents; Carcinogens; Humans; Hyperplasia; Immunohis | 2012 |
Hemicrania continua: an indomethacin-responsive case with an underlying malignant etiology.
Topics: Adenocarcinoma; Fatal Outcome; Humans; Indomethacin; Lung Neoplasms; Male; Middle Aged; Migraine Dis | 2002 |
Arachidonic acid metabolism in growth control of A549 human lung adenocarcinoma cells.
Topics: Adenocarcinoma; Arachidonic Acids; Carbon Radioisotopes; Cell Division; Cyclooxygenase Inhibitors; D | 2002 |
Requirement of cyclooxygenase-2 expression and prostaglandins for human prostate cancer cell invasion.
Topics: 6-Ketoprostaglandin F1 alpha; Adenocarcinoma; Arachidonic Acid; Cyclooxygenase 1; Cyclooxygenase 2; | 2002 |
Embryonal mass and hormone-associated effects of pregnancy inducing a differential growth of four murine tumors.
Topics: Adenocarcinoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Division; Estrogens; Female; | 2002 |
Prostaglandin e(2) suppresses NK activity in vivo and promotes postoperative tumor metastasis in rats.
Topics: Adenocarcinoma; Animals; Cyclooxygenase Inhibitors; Cytotoxicity, Immunologic; Dinoprostone; Dose-Re | 2003 |
Role of NF-kappaB and cytokine in experimental cancer cachexia.
Topics: Adenocarcinoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Composition; Cachexia; Coloni | 2003 |
The effects of TNF-alpha and inhibitors of arachidonic acid metabolism on human colon HT-29 cells depend on differentiation status.
Topics: Adenocarcinoma; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Butyrates; Caspase 3; Caspases; Cell | 2004 |
Valproic acid uptake by bovine brain microvessel endothelial cells: role of active efflux transport.
Topics: Adenocarcinoma; Animals; Biological Transport, Active; Brain; Cattle; Cells, Cultured; Cyclooxygenas | 2004 |
Colon carcinoma cell growth is associated with prostaglandin E2/EP4 receptor-evoked ERK activation.
Topics: Adenocarcinoma; Animals; Arachidonic Acid; Cell Division; Cell Line, Tumor; Colonic Neoplasms; Cycli | 2004 |
Indomethacin and ibuprofen preserve gastrocnemius muscle mass in mice bearing the colon-26 adenocarcinoma.
Topics: Adenocarcinoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Cachexia; Colonic Neo | 2004 |
Reduction of tumor progression and paraneoplastic syndrome development in murine lung adenocarcinoma by nonsteroidal antiinflammatory drugs.
Topics: Adenocarcinoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Division; Cell Survival; Chem | 2004 |
[Role of NF-kappa B in cancer cachexia].
Topics: Adenocarcinoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cachexia; Colonic Neoplasms; Indom | 2004 |
Celecoxib inhibits angiogenesis by inducing endothelial cell apoptosis in human pancreatic tumor xenografts.
Topics: Adenocarcinoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Celecoxib; Cyclooxygena | 2004 |
Different cell kinetic changes in rat stomach cancer after treatment with celecoxib or indomethacin: implications on chemoprevention.
Topics: Adenocarcinoma; Animals; Apoptosis; Celecoxib; Cell Division; Cyclooxygenase 2; Cyclooxygenase 2 Inh | 2005 |
Indomethacin preserves muscle mass and reduces levels of E3 ligases and TNF receptor type 1 in the gastrocnemius muscle of tumor-bearing mice.
Topics: Adenocarcinoma; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, We | 2005 |
Marginating pulmonary-NK activity and resistance to experimental tumor metastasis: suppression by surgery and the prophylactic use of a beta-adrenergic antagonist and a prostaglandin synthesis inhibitor.
Topics: Adenocarcinoma; Adrenergic beta-Antagonists; Animals; Cell Line, Tumor; Cyclooxygenase Inhibitors; D | 2005 |
Suppression of tumor cell invasion by cyclooxygenase inhibitors is mediated by thrombospondin-1 via the early growth response gene Egr-1.
Topics: Adenocarcinoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line, Tumor; Colorectal Neopl | 2005 |
Inhibition of human telomerase reverse transcriptase by nonsteroidal antiinflammatory drugs in colon carcinoma.
Topics: Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blotting, Western; Colonic Neoplas | 2006 |
Inhibition of tumor progression and paraneoplastic syndrome development in a murine lung adenocarcinoma by medroxyprogesterone acetate and indomethacin.
Topics: Adenocarcinoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Hormonal; A | 2006 |
Identification of specific genes and pathways involved in NSAIDs-induced apoptosis of human colon cancer cells.
Topics: Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Caco-2 Cells; Caspases; Colonic | 2006 |
Indomethacin therapy in symptomatic hepatic neoplasms.
Topics: Adenocarcinoma; Aged; Carcinoma, Hepatocellular; Carcinoma, Squamous Cell; Female; Humans; Indometha | 1982 |
Effect of interferon therapy on indomethacin-sensitive immunoregulation in the peripheral blood mononuclear cells of renal cell carcinoma patients.
Topics: Adenocarcinoma; Adult; Aged; Antibodies, Monoclonal; Cell Adhesion; Cell Division; Female; Humans; I | 1983 |
Inhibition of initiation and promotion by N-methylnitrosourea-induced colon carcinogenesis in rats by non-steroid anti-inflammatory agent indomethacin.
Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Female; Indomethacin; Methylnitrosourea; Nitrosourea Com | 1983 |
Growth inhibition of transplantable murine colon adenocarcinoma 38 by indomethacin.
Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Drug Therapy, Combination; Fluorouracil; Indomethacin; M | 1983 |
Nb rat prostate adenocarcinoma model androgen-sensitive tumor: metastasis control.
Topics: Adenocarcinoma; Animals; Castration; Cyclophosphamide; Disease Models, Animal; Heparin; Indomethacin | 1983 |
Increased survival of cancer-bearing mice treated with inhibitors of prostaglandin synthesis alone or with chemotherapy.
Topics: Adenocarcinoma; Animals; Biological Availability; Body Weight; Drug Therapy, Combination; Female; Fl | 1982 |
Antitumor activity of indomethacin on methylazoxymethanol-induced large bowel tumors in rats.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Indomethacin; Intestinal Neoplasms; Intestine, Large | 1980 |
Control of fever associated with visceral cancers by indomethacin.
Topics: Abdominal Neoplasms; Adenocarcinoma; Adult; Aged; Female; Fever; Humans; Indomethacin; Liver Neoplas | 1981 |
Inhibition of development of methylnitrosourea-induced rat colon tumors by indomethacin treatment.
Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Female; Indomethacin; Methylnitrosourea; Neoplasms, Expe | 1981 |
Influence of zymosan (a non-specific macrophage stimulator) and of indomethacin on liver tumours--an experimental study in rats.
Topics: Adenocarcinoma; Animals; Carcinoma, Hepatocellular; Drug Interactions; Drug Therapy, Combination; In | 1995 |
[The role of macrophage suppressor activity in the mechanism of metastasis after tumor resection].
Topics: Adenocarcinoma; Animals; Dinoprostone; Indomethacin; Lung Neoplasms; Macrophages; Male; Mammary Neop | 1995 |
[Synthesis of arachidonic acid cascade eicosanoids in tumors of various histogenesis in mice].
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Adenocarcinoma; Animals; Arachidonic Acid; Carcinoma, Le | 1995 |
No effect of kinins on DNA synthesis in LNCaP prostate cancer cells.
Topics: Adenocarcinoma; Bradykinin Receptor Antagonists; Dihydrotestosterone; DNA, Neoplasm; Drug Interactio | 1994 |
Bradykinin modulates mucin secretion but not synthesis from an intestinal goblet cell line.
Topics: Adenocarcinoma; Bradykinin; Colonic Neoplasms; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibo | 1994 |
Effect of polyunsaturated fatty acids on the growth of murine colon adenocarcinomas in vitro and in vivo.
Topics: Adenocarcinoma; Analysis of Variance; Animals; Arachidonic Acid; Benzeneacetamides; Cell Division; C | 1994 |
Effects of histamine type-2 receptor antagonists on indomethacin and IL-2 immunotherapy of metastasis.
Topics: Adenocarcinoma; Adjuvants, Immunologic; Animals; Cimetidine; Famotidine; Female; Histamine H2 Antago | 1993 |
Colon adenocarcinoma cells inhibit anti-CD3-activated killer cell induction.
Topics: Adenocarcinoma; Animals; CD3 Complex; Colonic Neoplasms; Female; Humans; Immune Tolerance; Indometha | 1994 |
Mechanism of muscle protein degradation in cancer cachexia.
Topics: Adenocarcinoma; Animals; Cachexia; Dinoprostone; Eicosapentaenoic Acid; Female; Indomethacin; Mice; | 1993 |
Promotion of metastases by tumor necrosis factor in rats bearing Dunning R3327 MAT-LyLu prostatic cancer.
Topics: Adenocarcinoma; Animals; Dinoprostone; Humans; Indomethacin; Lung Neoplasms; Male; Neoplasm Metastas | 1993 |
Eradication of spontaneous and experimental adenocarcinoma metastases with chronic indomethacin and intermittent IL-2 therapy.
Topics: Adenocarcinoma; Animals; Drug Administration Schedule; Female; Immunity, Cellular; Indomethacin; Int | 1993 |
Nonsteroidal antiinflammatory drugs inhibit the proliferation of colon adenocarcinoma cells: effects on cell cycle and apoptosis.
Topics: Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; CDC2 Protein Kinase; CD | 1996 |
Regulation of the promoter of the human corticotropin-releasing hormone gene in transfected human endometrial cells.
Topics: Adenocarcinoma; Corticotropin-Releasing Hormone; Cyclic AMP; Dexamethasone; Dinoprostone; Endometria | 1996 |
Indomethacin enhances the cytotoxicity of VCR and ADR in human pulmonary adenocarcinoma cells.
Topics: Adenocarcinoma; Adjuvants, Pharmaceutic; Coloring Agents; Doxorubicin; Drug Combinations; Drug Scree | 1997 |
Regulation of eicosanoid-like compound biosynthesis by IFN-gamma, IL-6, and EPA in human breast cancer cell line.
Topics: Adenocarcinoma; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Breast Neoplasms; | 1997 |
The influence of zymosan and indomethacin on liver and kidney tumor growth. An experimental study in rats.
Topics: Adenocarcinoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Antineoplas | 1997 |
Indomethacin interferes with EGF-induced activation of ornithine decarboxylase in gastric cancer cells.
Topics: Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Cell Division; Cell Movement; Enzyme Activa | 1998 |
Effects of NSAIDs on proliferation of gastric cancer cells in vitro: possible implication of cyclooxygenase-2 in cancer development.
Topics: Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Blotting, Northern; Blotting, We | 1998 |
Immunosuppressive cells in bone marrow of patients with stomach cancer.
Topics: Adenocarcinoma; Antibodies, Monoclonal; Bone Marrow; Bone Marrow Cells; Cell Adhesion; Cytotoxicity, | 1998 |
Clonogenic inactivation of colon cancer-derived cells treated with 5-fluorouracil and indomethacin in hybrid spheroids.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Cell Survival; Colonic Neoplasms; Cyclooxygenase In | 1998 |
Effectiveness of indomethacin as an antitumor agent in Colon 26-bearing conventional and nude mice, and telomerase activity in the tumors.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Colon; Colonic Neoplasms; Humans; Indomethacin; Live | 1999 |
[Neoplasm-inhibiting effect and sensitivity-promoting effect of indomethacin in vitro].
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; Cell Division; Co | 1997 |
Cell-type-specific activation of c-Jun N-terminal kinase by salicylates.
Topics: Acetaminophen; Adenocarcinoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Calcium-Ca | 1999 |
Cyclooxygenase-2 expression in human pancreatic adenocarcinomas.
Topics: Adenocarcinoma; Animals; Cell Line, Transformed; Codon; Cricetinae; Cyclooxygenase 2; Cyclooxygenase | 2000 |
Effect of prostaglandin E(2) on the proliferation, Ca(2+) mobilization and cAMP in HT-29 human colon adenocarcinoma cells.
Topics: Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Bombesin; Calcium; Cell Division; Colonic N | 2000 |
Effect of the nonsteroidal anti-inflammatory drug indomethacin on proliferation and apoptosis of colon carcinoma cells.
Topics: Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Apoptosis; Caco-2 Ce | 2001 |
Mechanisms of taxotere-related drug resistance in pancreatic carcinoma.
Topics: Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Antimetabolites, Antineoplastic; Antineopla | 2001 |
Synergistic effect of indomethacin with adriamycin and cisplatin on tumor growth.
Topics: Adenocarcinoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibiotics, Antineoplastic; Antin | 2001 |
MAPK (ERK2) kinase--a key target for NSAIDs-induced inhibition of gastric cancer cell proliferation and growth.
Topics: Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cell Division; Cyclooxygenase In | 2001 |
[Cytokines in experimental cancer cachexia].
Topics: Adenocarcinoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Glucose; Body Weight; Cachex | 2001 |
Dihydrotestosterone (DHT) modulates the ability of NSAIDs to induce apoptosis of prostate cancer cells.
Topics: Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cyclooxygenase 2; Cyclooxygenase | 2002 |
Cyclo-oxygenase inhibition reduces tumour growth and metastasis in an orthotopic model of breast cancer.
Topics: Adenocarcinoma; Angiogenesis Inhibitors; Animals; Apoptosis; Cyclooxygenase 1; Cyclooxygenase 2; Cyc | 2002 |
Letter: Indomethacin in hypercalcaemia.
Topics: Adenocarcinoma; Calcium; Humans; Hypercalcemia; Indomethacin; Kidney Neoplasms; Multiple Myeloma | 1975 |
Investigations on prostatic adenocarcinomas in rats.
Topics: Adenocarcinoma; Anesthetics; Animals; Aspirin; Cell Line; Female; Immunotherapy; Indomethacin; Lung | 1977 |
Elevated prostaglandins and suppressed parathyroid hormone associated with hypercalcemia and renal cell carcinoma.
Topics: Adenocarcinoma; Calcium; Humans; Hypercalcemia; Indomethacin; Kidney Cortex; Liver; Liver Neoplasms; | 1975 |
Letter: Indomethacin-responsive hypercalcemia.
Topics: Adenocarcinoma; Humans; Hypercalcemia; Indomethacin; Kidney Neoplasms; Male; Middle Aged | 1975 |
Interleukin-1 inhibits human thyroid carcinoma cell growth.
Topics: Adenocarcinoma; Animals; Blotting, Northern; Carcinoma, Papillary; Cattle; Cell Count; Cell Division | 1992 |
[The immunomodulating role of indomethacin in the chemoradiation treatment of inoperable patients with lung cancer].
Topics: Adenocarcinoma; Adjuvants, Immunologic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, S | 1992 |
Lipocortin 1 mediates dexamethasone-induced growth arrest of the A549 lung adenocarcinoma cell line.
Topics: Adenocarcinoma; Aldosterone; Annexins; Antibodies, Monoclonal; Calcium-Binding Proteins; Cell Divisi | 1992 |
Immunotherapy of mammary adenocarcinoma metastases in C3H/HeN mice with chronic administration of cyclo-oxygenase inhibitors alone or in combination with IL-2.
Topics: Adenocarcinoma; Animals; Cell Division; Cyclooxygenase Inhibitors; Drug Therapy, Combination; Female | 1992 |
Eicosanoids and linoleate-enhanced growth of mouse mammary tumor cells.
Topics: Adenocarcinoma; Animals; Cell Division; Cell Line; Cyclic AMP; Cyclic GMP; Eicosanoids; Female; Indo | 1991 |
The role of tumor-derived cytokines on the immune system of mice bearing a mammary adenocarcinoma. I. Induction of regulatory macrophages in normal mice by the in vivo administration of rGM-CSF.
Topics: Adenocarcinoma; Adjuvants, Immunologic; Animals; Antigens, Differentiation; Bone Marrow Cells; Dinop | 1991 |
Contribution of monocytes to the decreased lymphoproliferative response to phytohemagglutinin in patients with lung cancer.
Topics: Adenocarcinoma; Aged; Carcinoma; Dose-Response Relationship, Drug; Female; Humans; Indomethacin; Int | 1991 |
Effects of antiplatelet agents alone or in combinations on platelet aggregation and on liver metastases from a human pancreatic adenocarcinoma in the nude mouse.
Topics: Adenocarcinoma; Animals; Colforsin; Drug Interactions; Humans; Indomethacin; Ketoconazole; Liver Neo | 1991 |
Inhibitory effect of the non-steroidal anti-inflammatory drug, indomethacin on the naturally occurring carcinogen, 1-hydroxyanthraquinone in male ACI/N rats.
Topics: Adenocarcinoma; Animals; Anthraquinones; Carcinoma, Squamous Cell; Colonic Neoplasms; Enterocolitis; | 1991 |
Urticarial vasculitis occurring in association with visceral malignancy.
Topics: Adenocarcinoma; Aged; Antigen-Antibody Complex; Colon; Colonic Neoplasms; Female; Humans; Indomethac | 1990 |
Prostaglandin E2 from macrophages of murine splenocyte cultures inhibits the generation of lymphokine-activated killer cell activity.
Topics: Adenocarcinoma; Animals; Cells, Cultured; Diclofenac; Dinoprostone; Down-Regulation; Female; Immune | 1991 |
Control of fluid transport in human rectal adenocarcinoma cells (HRA-19) in monolayer and collagen gel cultures.
Topics: Adenocarcinoma; Cholera Toxin; Colforsin; Dinoprostone; Epithelium; Extracellular Space; Humans; Ind | 1990 |
Efflux of bis-carboxyethyl-carboxyfluorescein (BCECF) by a novel ATP-dependent transport mechanism in epithelial cells.
Topics: Adenocarcinoma; Adenosine Triphosphate; Animals; Cell Line; Epithelium; Fluoresceins; Fluorescent Dy | 1990 |
[Effects of indomethacin and BCG vaccine on growth of transplanted tumors in mice].
Topics: Adenocarcinoma; Animals; BCG Vaccine; Indomethacin; Liver Neoplasms, Experimental; Lung Neoplasms; M | 1990 |
Splenic natural cytotoxic activity is enhanced during growth of a murine fibrosarcoma.
Topics: Adenocarcinoma; Alprostadil; Animals; Cytotoxicity, Immunologic; Dinoprostone; Fibrosarcoma; Indomet | 1990 |
[Assessment of the activity of tumor necrosis factor in normal state and in ovarian tumors].
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Cells, Cultured; Cystadenoma | 1990 |
Growth inhibition and eicosanoid metabolism in the R3230AC mammary adenocarcinoma by interferon.
Topics: Adenocarcinoma; Animals; Arachidonic Acid; Arachidonic Acids; Female; Indomethacin; Interferons; Mam | 1986 |
Effect of indomethacin on tumor-infiltrating lymphocytes of a spontaneously developed murine mammary adenocarcinoma.
Topics: Adenocarcinoma; Animals; Cytotoxicity, Immunologic; Female; G(M1) Ganglioside; Glycosphingolipids; I | 1989 |
Comparison of the effects of peritoneal and spleen cells of syngeneic or allogeneic origin on the take of transplantable murine tumours.
Topics: Acenocoumarol; Adenocarcinoma; Animals; Carcinoma; Indomethacin; Mice; Mice, Inbred BALB C; Mice, In | 1989 |
Characterization of activated peritoneal cells inhibiting the take of transplantable murine tumours.
Topics: Acenocoumarol; Adenocarcinoma; Animals; Antibodies; Carcinoma; Complement System Proteins; Female; G | 1989 |
Modulation of prostaglandin biosynthesis in hypoxic murine mammary adenocarcinoma cells by misonidazole.
Topics: Adenocarcinoma; Anaerobiosis; Animals; Cell Line; Hypoxia; Indomethacin; Kinetics; Lung Neoplasms; M | 1989 |
The relationship between clinical stage, natural killer activity and related immunological parameters in adenocarcinoma of the prostate.
Topics: Adenocarcinoma; Aged; Cimetidine; Cytotoxicity, Immunologic; Humans; Indomethacin; Interleukin-2; Ki | 1989 |
Antitumor activity of indomethacin in mice bearing advanced colon 26 carcinoma compared with those with early transplants.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cell Division; Colonic Neoplasms; Dinoprostone; Indo | 1989 |
Effect of indomethacin in autotransplanted colonic tumors.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Carcinogens; Colonic Neoplasms; Dimethylhydrazines; | 1989 |
Human PC-3 prostate cell line DNA synthesis is suppressed by eicosatetraynoic acid, an in vitro inhibitor of arachidonic acid metabolism.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Adenocarcinoma; Arachidonic Acid; Arachidonic Acids; Calcimycin; Cy | 1988 |
Anti-tumor activity of recombinant mouse tumor necrosis factor (TNF) on colon cancer in rats is promoted by recombinant rat interferon gamma; toxicity is reduced by indomethacin.
Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Colonic Neop | 1987 |
Inhibition of human colon tumor growth in nude mice by indomethacin.
Topics: Adenocarcinoma; Animals; Cell Division; Colonic Neoplasms; Humans; Indomethacin; Mice; Mice, Nude; N | 1985 |
[Increased mucosal ornithine decarboxylase activity in carcinoma-bearing large bowel and its inhibition by indomethacin].
Topics: Adenocarcinoma; Adenoma; Adult; Aged; Aged, 80 and over; Depression, Chemical; Female; Humans; Indom | 1988 |
Augmented antitumor effect of recombinant human interleukin-1 alpha by indomethacin.
Topics: Adenocarcinoma; Animals; Cell Division; Drug Administration Schedule; Drug Synergism; Indomethacin; | 1988 |
[Nature of the modifying action of polyunsaturated fatty acids on the growth of transplantable tumors of different types].
Topics: Adenocarcinoma; Animals; Fatty Acids, Unsaturated; Indomethacin; Leukemia L1210; Mammary Neoplasms, | 1988 |
[Prevention of peritoneal carcinomatosis recurrence with a prostaglandin synthesis inhibitor, indomethacin].
Topics: Adenocarcinoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Colonic Neoplasms; Dinoprostone; D | 1987 |
Modulation of the immunosuppressive effects of splenic macrophages in Fischer rats bearing adenocarcinoma 13762.
Topics: Adenocarcinoma; Animals; Female; Glycolipids; Immune Tolerance; Indomethacin; Lymphocyte Activation; | 1985 |
Antitumor activity in a rat mammary adenocarcinoma: the effect of cyclooxygenase inhibitors and immunization against prostaglandin E2.
Topics: Adenocarcinoma; Animals; Antibodies; Antineoplastic Agents; Cell Line; Cyclooxygenase Inhibitors; Di | 1985 |
Acute renal failure and death following sequential intermediate-dose methotrexate and 5-FU: a possible adverse effect due to concomitant indomethacin administration.
Topics: Acute Kidney Injury; Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic N | 1985 |
Relationships of prostaglandin E and natural killer sensitivity to metastatic potential in murine mammary adenocarcinomas.
Topics: Adenocarcinoma; Animals; Catechols; Cell Line; Female; Indomethacin; Killer Cells, Natural; Male; Ma | 1985 |
Metastasis in the androgen-insensitive Nb rat prostatic carcinoma system.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cortisone; Disease Models, Animal; Drug Therapy, Com | 1985 |
Prostaglandin E (PGE) control of cell proliferation in vitro: characteristics of HT-29.
Topics: Adenocarcinoma; Bucladesine; Carcinoma, Squamous Cell; Cell Count; Cell Division; Cell Line; Culture | 1974 |
Indomethacin-responsive hypercalcemia in a patient with renal-cell adenocarcinoma.
Topics: Adenocarcinoma; Administration, Oral; Calcium; Humans; Hypercalcemia; Indomethacin; Kidney Neoplasms | 1974 |