indomethacin has been researched along with Acute-Phase Reaction in 10 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Acute-Phase Reaction: An early local inflammatory reaction to insult or injury that consists of fever, an increase in inflammatory humoral factors, and an increased synthesis by hepatocytes of a number of proteins or glycoproteins usually found in the plasma.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Acetylsalicic acid and indomethacin suppress the increase of alpha-amanitin sensitive RNA synthesis (pre-mRNA), but not that of alpha-amanitin resistant RNA synthesis (pre-rRNA), which occur in liver nuclei a few hours after the start of turpentine-induced inflammation in the skin." | 3.67 | Prostaglandin synthesis and early biochemical events in the liver cells during the acute-phase response. ( Aletti, MG; Bernelli-Zazzera, A; Ferioli, ME; Piccoletti, R; Scalabrino, G, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (40.00) | 18.7374 |
| 1990's | 4 (40.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Adham, KG | 1 |
| Al-Humaidhi, EM | 1 |
| Daghestani, MH | 1 |
| Aleisa, NA | 1 |
| Farhood, MH | 1 |
| Tugendreich, S | 1 |
| Pearson, CI | 1 |
| Sagartz, J | 1 |
| Jarnagin, K | 1 |
| Kolaja, K | 1 |
| Johnson, RW | 1 |
| von Borell, E | 1 |
| Markewitz, A | 1 |
| Faist, E | 1 |
| Lang, S | 1 |
| Endres, S | 1 |
| Hültner, L | 1 |
| Reichart, B | 1 |
| Abraham, EJ | 1 |
| Morris-Hardeman, JN | 1 |
| Swenson, LM | 1 |
| Knoppel, EL | 1 |
| Ramanathan, B | 1 |
| Wright, KJ | 1 |
| Grieger, DM | 1 |
| Minton, JE | 1 |
| Paul-Eugene, N | 1 |
| Kolb, JP | 1 |
| Abadie, A | 1 |
| Gordon, J | 1 |
| Delespesse, G | 1 |
| Sarfati, M | 1 |
| Mencia-Huerta, JM | 1 |
| Braquet, P | 1 |
| Dugas, B | 1 |
| O'Neill, LA | 1 |
| Lewis, GP | 1 |
| Scalabrino, G | 2 |
| Ferioli, ME | 2 |
| Piccoletti, R | 2 |
| Bernelli-Zazzera, A | 2 |
| Aletti, MG | 1 |
| Morimoto, A | 1 |
| Murakami, N | 1 |
| Watanabe, T | 1 |
1 review available for indomethacin and Acute-Phase Reaction
| Article | Year |
|---|---|
Pituitary function in the acute phase response in domestic farm animals: cytokines, prostaglandins, and secretion of ACTH.
Topics: Acute-Phase Reaction; Adrenocorticotropic Hormone; Amino Acid Sequence; Animals; Animals, Domestic; | 1998 |
1 trial available for indomethacin and Acute-Phase Reaction
| Article | Year |
|---|---|
Regulation of acute phase response after cardiopulmonary bypass by immunomodulation.
Topics: Acute-Phase Reaction; Adjuvants, Immunologic; Aged; Cardiac Surgical Procedures; Cardiopulmonary Byp | 1993 |
8 other studies available for indomethacin and Acute-Phase Reaction
| Article | Year |
|---|---|
Protective role of indomethacin on lipopolysaccharide-stimulated fever induction and cerebral catecholamine biosynthesis in Wistar rat.
Topics: Acute-Phase Reaction; Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Temperature; Brain; Dop | 2012 |
NSAID-induced acute phase response is due to increased intestinal permeability and characterized by early and consistent alterations in hepatic gene expression.
Topics: Acute-Phase Reaction; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemokine CCL2; Chemokines, | 2006 |
Lipopolysaccharide-induced sickness behavior in pigs is inhibited by pretreatment with indomethacin.
Topics: Acute Disease; Acute-Phase Reaction; Analysis of Variance; Animals; Behavior, Animal; Body Temperatu | 1994 |
Ligation of CD23 triggers cAMP generation and release of inflammatory mediators in human monocytes.
Topics: Acute-Phase Reaction; Albuterol; Calcium; Cells, Cultured; Cyclic AMP; Dose-Response Relationship, I | 1992 |
Inhibitory effects of diclofenac and indomethacin on interleukin-1-induced changes in PGE2 release. A novel effect on free arachidonic acid levels in human synovial cells.
Topics: Acute-Phase Reaction; Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Diclofenac; Dinoprostone | 1989 |
Activation of polyamine biosynthetic decarboxylases during the acute phase response of rat liver.
Topics: Acute-Phase Reaction; Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Enzyme Activation; | 1987 |
Prostaglandin synthesis and early biochemical events in the liver cells during the acute-phase response.
Topics: Acute-Phase Reaction; Animals; Aspirin; Dinoprost; Dinoprostone; Indomethacin; Inflammation; Liver; | 1987 |
Is the central arachidonic acid cascade system involved in the development of acute-phase response in rabbits?
Topics: Acute-Phase Reaction; Animals; Arachidonic Acid; Arachidonic Acids; Body Temperature; Cerebral Ventr | 1988 |