indomethacin has been researched along with Active Hyperemia in 76 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In patients with measles during the first two weeks of infection, ketorolac and indomethacin were more effective than artificial tears in decreasing conjunctival hyperemia, but burning sensations, foreign-body sensations, and photophobia were unaffected." | 9.12 | The effects of topical ketorolac and indomethacin on measles conjunctivitis: randomized controlled trial. ( Arici, MK; Arslan, OS; Erdem, H; Erdogan, H; Pahsa, A; Toker, MI; Topalkara, A, 2006) |
| "We investigated antioxidative activity and the effect of indomethacin, an agent that inhibits cyclooxygenase, on extracellular glutamate and cerebral blood flow in cerebral ischemia in gerbils." | 7.72 | Suppression of hyperemia and DNA oxidation by indomethacin in cerebral ischemia. ( Hayashida, Y; Hirakawa, H; Itano, T; Kasai, H; Konishi, R; Miyamoto, O; Tamae, K, 2003) |
| "The mechanism of isoflurane-induced cerebral hyperemia is poorly understood." | 7.69 | Nitric oxide and prostanoids contribute to isoflurane-induced cerebral hyperemia in pigs. ( Helfaer, MA; Kirsch, JR; McPherson, RW; Moore, LE; Tobin, JR; Traystman, RJ, 1994) |
| "The effects of indomethacin and meclofenamate on active hyperemia following sustained, maximal isometric contractions were studied in free-flowing dog gracilis muscles." | 7.67 | Indomethacin and meclofenamate potentiation of skeletal muscle active hyperemia. ( Klabunde, RE; Rankin, RS, 1985) |
| "A nonlymphokine mediator of hyperemia has been shown to be secreted by both rabbit peritoneal exudate cells stimulated with 5% glycogen and by concanavalin A treated cells from afferent lymph of sheep." | 7.66 | Secretion of a hyperemia-inducing moiety by mitogen or glycogen stimulated mononuclear inflammatory cells of sheep and rabbit. ( Hay, JB; Vadas, P, 1980) |
| "Direct, in vivo microcirculatory experiments were undertaken with anesthetized rats to determine whether prostaglandin (PG)-like compounds and histamine may mediate post-occlusion hyperemia in single mesenteric arterioles." | 7.66 | Role of prostaglandins and histamine in reactive hyperemia: in-vivo studies on single mesenteric arterioles. ( Altura, BM, 1978) |
| "The effect of indomethacin (10 mg/kg) on the distribution of cortical blood flow during postocclusive reactive hyperemia was evaluated in denervated kidneys of anesthetized rabbits by the radioactive microsphere technique." | 7.65 | Failure to abolish reactive hyperemia by indomethacin in denervated kidneys of rabbits. ( Aizawa, C; Honda, N, 1977) |
| "In patients with measles during the first two weeks of infection, ketorolac and indomethacin were more effective than artificial tears in decreasing conjunctival hyperemia, but burning sensations, foreign-body sensations, and photophobia were unaffected." | 5.12 | The effects of topical ketorolac and indomethacin on measles conjunctivitis: randomized controlled trial. ( Arici, MK; Arslan, OS; Erdem, H; Erdogan, H; Pahsa, A; Toker, MI; Topalkara, A, 2006) |
| " We tested the hypothesis that adenosine, prostaglandins, and NO act in synergy to regulate skeletal muscle hyperemia by determining the following: (1) the effect of adenosine receptor blockade on skeletal muscle exercise hyperemia with and without simultaneous inhibition of prostaglandins (indomethacin; 0." | 3.75 | Adenosine contributes to blood flow regulation in the exercising human leg by increasing prostaglandin and nitric oxide formation. ( Hellsten, Y; Mortensen, SP; Nyberg, M; Saltin, B; Thaning, P, 2009) |
| " In nondiabetic rats, stimulation of the endothelium by locally administered ACh or bradykinin-induced transient renal hyperemia." | 3.74 | In vivo regulation of endothelium-dependent vasodilation in the rat renal circulation and the effect of streptozotocin-induced diabetes. ( Edgley, AJ; Evans, RG; Parkington, HC; Skordilis, C; Tare, M, 2008) |
| "We investigated antioxidative activity and the effect of indomethacin, an agent that inhibits cyclooxygenase, on extracellular glutamate and cerebral blood flow in cerebral ischemia in gerbils." | 3.72 | Suppression of hyperemia and DNA oxidation by indomethacin in cerebral ischemia. ( Hayashida, Y; Hirakawa, H; Itano, T; Kasai, H; Konishi, R; Miyamoto, O; Tamae, K, 2003) |
| "The mechanism of isoflurane-induced cerebral hyperemia is poorly understood." | 3.69 | Nitric oxide and prostanoids contribute to isoflurane-induced cerebral hyperemia in pigs. ( Helfaer, MA; Kirsch, JR; McPherson, RW; Moore, LE; Tobin, JR; Traystman, RJ, 1994) |
| " Studies were conducted under control conditions and in the presence of four inhibitors of potential mediators of the reactive hyperemia response: the nitric oxide synthase inhibitor NG-nitro-L-arginine methyl ester (30 microM), the adenosine antagonist 8-(p-sulfophenyl)theophylline (50 microM), the K+ cyclic adenosine triphosphate-dependent channel antagonist glibenclamide (10 microM), and the cyclooxygenase inhibitor indomethacin (10 microM)." | 3.69 | Myocardial reactive hyperemia in experimental chronic heart failure: evidence for the role of K+ adenosine triphosphate-dependent channels and cyclooxygenase activity. ( Dumont, L; Fontaine, E; Jasmin, G; Véronneau, M; Viau, S, 1997) |
| " It has also been observed that the cyclooxygenase inhibitor indomethacin attenuates hypoxic hyperemia in piglets." | 3.69 | Relationship between opioids and prostaglandins in hypoxia-induced vasodilation of pial arteries in the newborn pig. ( Armstead, WM, 1996) |
| "The gastric hyperemia induced by intragastric 2 mol/L saline was completely blocked only by indomethacin." | 3.68 | Mechanism of gastric hyperemia induced by intragastric hypertonic saline in rats. ( Domek, MJ; Endoh, K; Kao, J; Leung, FW, 1993) |
| "Experiments on anesthesized dogs demonstrated that gastrocnemius muscle vessels working hyperemia substantially decreased after chemical destruction of endothelium by saponin, inhibition of endothelium-derived relaxing factor synthesis by gossypol and inhibition of quanylate cyclase by methylene blue." | 3.68 | [The role of the endothelium in the development of functional hyperemia of the skeletal muscles]. ( Kindybaliuk, AM; Sagach, VF, 1991) |
| "The experiments on anesthetized dogs demonstrated that reaction of the femoral vessels reactive hyperemia essentially decreased after chemical inhibition of endothelium by saponin, inhibition of lipoxygenase by quercetin and guanylate cyclase by methylene blue." | 3.67 | [Role of the endothelium in the development of reactive hyperemia]. ( Sagach, VF; Tkachenko, MN, 1989) |
| "The effects of indomethacin and meclofenamate on active hyperemia following sustained, maximal isometric contractions were studied in free-flowing dog gracilis muscles." | 3.67 | Indomethacin and meclofenamate potentiation of skeletal muscle active hyperemia. ( Klabunde, RE; Rankin, RS, 1985) |
| "Following the induction of immunogenic uveitis betamethasone and dexamethasone reduced conjunctiva and iris hyperemia and aqueous flare." | 3.66 | Anti-inflammatory effects of betamethasone phosphate, dexamethasone phosphate and indomethacin on rabbit ocular inflammation induced by bovine serum albumin. ( Bhattacherjee, P; Eakins, KE; Kulkarni, PS; Srinivasan, BD, 1981) |
| "A nonlymphokine mediator of hyperemia has been shown to be secreted by both rabbit peritoneal exudate cells stimulated with 5% glycogen and by concanavalin A treated cells from afferent lymph of sheep." | 3.66 | Secretion of a hyperemia-inducing moiety by mitogen or glycogen stimulated mononuclear inflammatory cells of sheep and rabbit. ( Hay, JB; Vadas, P, 1980) |
| "Direct, in vivo microcirculatory experiments were undertaken with anesthetized rats to determine whether prostaglandin (PG)-like compounds and histamine may mediate post-occlusion hyperemia in single mesenteric arterioles." | 3.66 | Role of prostaglandins and histamine in reactive hyperemia: in-vivo studies on single mesenteric arterioles. ( Altura, BM, 1978) |
| " sar1gly8AII, abolished the hypertensive response to acute ureteral obstruction, and pretreatment with 2 mg/kg of either indomethacin (n=6) or meclofenamate (n=3), 15 min before obstruction, prevented the hyperemic response." | 3.66 | Prostaglandin-mediated hyperemia and renin-mediated hypertension during acute ureteral obstruction. ( Aisenbrey, G; Burke, TJ; Cadnapaphornchai, P; McDonald, KM; Schrier, RW, 1978) |
| "The effect of indomethacin (10 mg/kg) on the distribution of cortical blood flow during postocclusive reactive hyperemia was evaluated in denervated kidneys of anesthetized rabbits by the radioactive microsphere technique." | 3.65 | Failure to abolish reactive hyperemia by indomethacin in denervated kidneys of rabbits. ( Aizawa, C; Honda, N, 1977) |
| "In two series of experiments we studied the effects of indomethacin on (a) coronary reactive hyperemia and, (b) renal blood flow, autoregulation, and reactive dilation." | 3.65 | Effects of indomethacin on local blood flow regulation in canine heart and kidney. ( Ehrhart, IC; Haddy, FJ; Owen, TL; Scott, JB; Weidner, WJ, 1975) |
| "Ibuprofen was the most efficient agent, inhibiting the total reactive hyperemia by more than 70%, and naproxen was least active, producing about 35% inhibition." | 2.65 | Effect of different prostaglandin synthesis inhibitors on post-occlusive blood flow in human forearm. ( Carlsson, I; Wennmalm, A, 1983) |
| "This hyperemia was significantly (p less than 0." | 2.65 | Cigarette smoking, prostaglandins and reactive hyperemia. ( Wennmalm, A, 1979) |
| "Before hyperbaric oxygenation-induced convulsions in rats the initial decrease in blood flow gave place to hyperemia, Po(2) increased." | 1.33 | Effect of indomethacin on cerebral blood flow and development of oxygen convulsions. ( Alekseeva, OS; Gutsaeva, DR; Khmel'nitskii, AV; Moskvin, AN; Sharapov, OI, 2006) |
| "Coronary reactive hyperemia was observed even after the inhibition of nitric oxide synthase by N(omega)-nitro-L-arginine methylester (L-NAME)." | 1.30 | Types of potassium channels involved in coronary reactive hyperemia depend on duration of preceding ischemia in rat hearts. ( Ito, T; Mokuno, S; Murase, K; Okumura, K; Shinoda, M; Toki, Y, 1997) |
| "Indomethacin treatment or removal of the venular endothelium will attenuate functional arteriolar vasodilation in the hamster cremaster muscle." | 1.30 | Influence of venular prostaglandin release on arteriolar diameter during functional hyperemia. ( Boyd, D; Gardner, AL; Hester, RL; McKay, MK, 1998) |
| "Pretreatment with indomethacin partially blocked the enhancing effect of SP on protein leakage, while it did not block that of NKA." | 1.30 | Tachykinins as enhancers of prostaglandin E2-induced intraocular inflammation. ( Hamada, M; Shirasawa, E; Tsuji, F, 1998) |
| "Gastric hyperemia is mediated by CGRP contained in capsaicin-sensitive afferent fibers, whereas acid secretion is under the inhibitory influence of prostaglandins and CGRP." | 1.30 | Mechanisms mediating gastric hyperemic and acid responses to central TRH analog at a cytoprotective dose. ( Guth, PH; Király, A; Sütó, G; Taché, Y, 1997) |
| "Indomethacin was also found to be effective in suppressing reactive hyperemia." | 1.29 | Evidence for sensory nerve involvement in cutaneous reactive hyperemia in humans. ( Larkin, SW; Williams, TJ, 1993) |
| "This hyperemia was reduced by L-NMMA but not by 8-PT." | 1.29 | Role of adenosine and nitric oxide in the hyperemic response to superficial and deep gastric mucosal injury and H+ back-diffusion in cats. ( Gislason, H; Svanes, K; Sørbye, H; Varhaug, P; Waldum, HL, 1996) |
| "Reactive hyperemia was also not affected by 30 microM theophylline (an adenosine antagonist) or suffusion of catalase (160 U/ml) plus superoxide dismutase (240 U/ml)." | 1.28 | Similarities in the pharmacological modulation of reactive hyperemia and vasodilation to hydrogen peroxide in rat skeletal muscle arterioles: effects of probes for endothelium-derived mediators. ( Kaley, G; Messina, EJ; Rodenburg, JM; Wolin, MS, 1990) |
| " Dose-response experiments performed with 2 to 90 per cent (v/v) zymosan-activated plasma showed a direct correlation between the rate of neutrophil influx and the degree of vascular permeability in blood flow." | 1.26 | Vascular responses during acute neutrophilic inflammation. Their relationship to in vivo neutrophil emigration. ( Issekutz, AC, 1981) |
| "The effects of the inhibitors on reactive hyperemia resulting from 5-, 10-, 15-, and 20-second occlusions and the dilation resulting from 90-second exposure to 8% O2 were also examined." | 1.26 | Prostaglandins and the control of blood flow in the canine myocardium. ( Hintze, TH; Kaley, G, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 39 (51.32) | 18.7374 |
| 1990's | 24 (31.58) | 18.2507 |
| 2000's | 11 (14.47) | 29.6817 |
| 2010's | 1 (1.32) | 24.3611 |
| 2020's | 1 (1.32) | 2.80 |
| Authors | Studies |
|---|---|
| Šušnjara, P | 1 |
| Mihaljević, Z | 1 |
| Stupin, A | 1 |
| Kolobarić, N | 1 |
| Matić, A | 1 |
| Jukić, I | 1 |
| Kralik, Z | 1 |
| Kralik, G | 1 |
| Miloloža, A | 1 |
| Pavošević, T | 1 |
| Šerić, V | 1 |
| Lončarić, Z | 1 |
| Kerovec, D | 1 |
| Galović, O | 1 |
| Drenjančević, I | 1 |
| Taylor, JL | 1 |
| Hines, CN | 1 |
| Nicholson, WT | 1 |
| Joyner, MJ | 1 |
| Barnes, JN | 1 |
| Edgley, AJ | 1 |
| Tare, M | 1 |
| Evans, RG | 1 |
| Skordilis, C | 1 |
| Parkington, HC | 1 |
| Mortensen, SP | 2 |
| Nyberg, M | 1 |
| Thaning, P | 1 |
| Saltin, B | 2 |
| Hellsten, Y | 2 |
| Miyamoto, O | 1 |
| Tamae, K | 1 |
| Kasai, H | 1 |
| Hirakawa, H | 1 |
| Hayashida, Y | 1 |
| Konishi, R | 1 |
| Itano, T | 1 |
| Rogers, J | 1 |
| Sheriff, DD | 1 |
| Toker, MI | 1 |
| Erdem, H | 1 |
| Erdogan, H | 1 |
| Arici, MK | 1 |
| Topalkara, A | 1 |
| Arslan, OS | 1 |
| Pahsa, A | 1 |
| González-Alonso, J | 1 |
| Damsgaard, R | 1 |
| Moskvin, AN | 1 |
| Alekseeva, OS | 1 |
| Gutsaeva, DR | 1 |
| Khmel'nitskii, AV | 1 |
| Sharapov, OI | 1 |
| Yada, T | 1 |
| Shimokawa, H | 1 |
| Morikawa, K | 1 |
| Takaki, A | 1 |
| Shinozaki, Y | 1 |
| Mori, H | 1 |
| Goto, M | 1 |
| Ogasawara, Y | 1 |
| Kajiya, F | 1 |
| Siesjö, BK | 1 |
| Nilsson, B | 1 |
| Carlsson, I | 3 |
| Wennmalm, A | 6 |
| Lorenzini, P | 1 |
| Linde, B | 1 |
| Barnett, AH | 1 |
| Koullapis, EN | 1 |
| Nicolaides, K | 1 |
| Pyke, DA | 1 |
| Spiliopoulos, AJ | 1 |
| Issekutz, AC | 1 |
| Gallavan, RH | 1 |
| Chou, CC | 1 |
| Vadas, P | 2 |
| Hay, JB | 2 |
| Kulkarni, PS | 1 |
| Bhattacherjee, P | 1 |
| Eakins, KE | 1 |
| Srinivasan, BD | 1 |
| Koyama, K | 1 |
| Kaneko, I | 1 |
| Mori, K | 1 |
| Moore, LE | 1 |
| Kirsch, JR | 1 |
| Helfaer, MA | 1 |
| Tobin, JR | 1 |
| McPherson, RW | 1 |
| Traystman, RJ | 1 |
| King-Vanvlack, CE | 1 |
| Curtis, SE | 1 |
| Mewburn, JD | 1 |
| Cain, SM | 1 |
| Chapler, CK | 1 |
| Gislason, H | 2 |
| Sørbye, H | 2 |
| Abdi-Dezfuli, F | 1 |
| Waldum, HL | 2 |
| Svanes, K | 2 |
| Chłopicki, S | 1 |
| Gryglewski, RJ | 2 |
| Tasdemiroglu, E | 1 |
| Christenberry, PD | 1 |
| Ardell, JL | 1 |
| Chronister, RB | 1 |
| Taylor, AE | 1 |
| Herbert, MK | 1 |
| Holzer, P | 2 |
| Lopez-Belmonte, J | 1 |
| Whittle, BJ | 1 |
| Endoh, K | 1 |
| Kao, J | 1 |
| Domek, MJ | 1 |
| Leung, FW | 1 |
| Andersen, PH | 1 |
| Broichmann, PW | 1 |
| Maibach, H | 1 |
| Larkin, SW | 1 |
| Williams, TJ | 1 |
| Armstead, WM | 1 |
| Tanaka, S | 1 |
| Kaunitz, JD | 1 |
| Varhaug, P | 1 |
| Chlopicki, S | 1 |
| Niezabitowski, P | 1 |
| Jakubowski, A | 1 |
| Lomnicka, M | 1 |
| Király, A | 1 |
| Sütó, G | 1 |
| Guth, PH | 1 |
| Taché, Y | 1 |
| Shinoda, M | 1 |
| Toki, Y | 1 |
| Murase, K | 1 |
| Mokuno, S | 1 |
| Okumura, K | 1 |
| Ito, T | 1 |
| Viau, S | 1 |
| Fontaine, E | 1 |
| Véronneau, M | 1 |
| Jasmin, G | 1 |
| Dumont, L | 1 |
| McKay, MK | 1 |
| Gardner, AL | 1 |
| Boyd, D | 1 |
| Hester, RL | 1 |
| Tsuji, F | 1 |
| Hamada, M | 1 |
| Shirasawa, E | 1 |
| Naylor, HL | 1 |
| Shoemaker, JK | 1 |
| Brock, RW | 1 |
| Hughson, RL | 1 |
| Ruh, J | 2 |
| Vogel, F | 2 |
| Schmidt, E | 2 |
| Werner, M | 1 |
| Klar, E | 1 |
| Secchi, A | 1 |
| Gebhard, MM | 1 |
| Glaser, F | 1 |
| Herfarth, C | 1 |
| Shimizu, K | 1 |
| Bari, F | 1 |
| Busija, DW | 2 |
| Altura, BM | 1 |
| Andersson, RG | 1 |
| Aberg, G | 1 |
| Brattsand, R | 1 |
| Ericsson, E | 1 |
| Lundholm, L | 1 |
| Beaty, O | 1 |
| Donald, DE | 1 |
| Deutsch, TA | 1 |
| Hughes, WF | 1 |
| Cuypers, J | 1 |
| Cuevas, A | 1 |
| Duisberg, R | 1 |
| Cadnapaphornchai, P | 1 |
| Aisenbrey, G | 1 |
| McDonald, KM | 1 |
| Burke, TJ | 1 |
| Schrier, RW | 1 |
| Vane, JR | 2 |
| McGiff, JC | 1 |
| Alexander, RW | 1 |
| Kent, KM | 1 |
| Pisano, JJ | 1 |
| Keiser, HR | 1 |
| Cooper, T | 1 |
| Hintze, TH | 1 |
| Kaley, G | 3 |
| Giles, RW | 1 |
| Wilcken, DE | 1 |
| Messina, EJ | 2 |
| Weiner, R | 1 |
| Aizawa, C | 1 |
| Honda, N | 1 |
| Kilbom, A | 1 |
| Block, AJ | 1 |
| Feinberg, H | 1 |
| Herbaczynska-Cedro, K | 1 |
| Obstbaum, SA | 1 |
| Podos, SM | 1 |
| Owen, TL | 1 |
| Ehrhart, IC | 1 |
| Weidner, WJ | 1 |
| Scott, JB | 1 |
| Haddy, FJ | 1 |
| Lippe, IT | 1 |
| Sagach, VF | 3 |
| Kindybaliuk, AM | 1 |
| Wolin, MS | 1 |
| Rodenburg, JM | 1 |
| Sitzmann, JV | 1 |
| Bulkley, GB | 1 |
| Mitchell, MC | 1 |
| Campbell, K | 1 |
| Tkachenko, MN | 2 |
| Dmitrieva, AV | 1 |
| Phillis, JW | 1 |
| DeLong, RE | 1 |
| Towner, JK | 1 |
| Rankin, RS | 1 |
| Klabunde, RE | 1 |
| Kimura, T | 1 |
| Satoh, S | 1 |
| Leffler, CW | 1 |
| Fletcher, AM | 1 |
| Beasley, DG | 1 |
| Hessler, JR | 1 |
| Green, RS | 1 |
| Bowery, B | 1 |
| Lewis, GP | 1 |
| Neufeld, AH | 1 |
| Chavis, RM | 1 |
| Sears, ML | 1 |
| Ryan, MJ | 1 |
| Clark, KE | 1 |
| Van Orden, DE | 1 |
| Farley, D | 1 |
| Edvinsson, L | 1 |
| Sjoberg, NO | 1 |
| Van Orden, LS | 1 |
| Brody, MJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Artificial Tears Versus Preservative Free Ketorolac Trometamol 0.45% for Treatment of Acute Viral Conjunctivitis[NCT01799863] | Phase 2/Phase 3 | 50 participants (Actual) | Interventional | 2012-06-30 | Completed | ||
| Cerebral Vasodilator Responses in Sedentary and Exercise Trained Humans[NCT02653638] | Early Phase 1 | 80 participants (Actual) | Interventional | 2016-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for indomethacin and Active Hyperemia
| Article | Year |
|---|---|
Prostaglandins and the cerebral circulation.
Topics: Animals; Brain; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Dose-Response Relationship, | 1982 |
Interaction of nicotine and prostaglandins in the cardiovascular system.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Cardiov | 1982 |
7 trials available for indomethacin and Active Hyperemia
| Article | Year |
|---|---|
Consumption of Nutritionally Enriched Hen Eggs Enhances Endothelium-Dependent Vasodilation via Cyclooxygenase Metabolites in Healthy Young People-A Randomized Study.
Topics: Acetylcholine; Animals; Chickens; Cyclooxygenase 1; Cyclooxygenase 2; Endothelium; Endothelium, Vasc | 2023 |
The effects of topical ketorolac and indomethacin on measles conjunctivitis: randomized controlled trial.
Topics: Administration, Topical; Adult; Anti-Inflammatory Agents, Non-Steroidal; Conjunctiva; Conjunctivitis | 2006 |
Effect of different prostaglandin synthesis inhibitors on post-occlusive blood flow in human forearm.
Topics: Adolescent; Adult; Aspirin; Cyclooxygenase Inhibitors; Diclofenac; Female; Forearm; Humans; Hyperemi | 1983 |
[The effect of indomethacin suppository in preventing mesenteric traction syndrome].
Topics: Adult; Anesthesia, Epidural; Anesthesia, General; Anti-Inflammatory Agents, Non-Steroidal; Female; H | 1995 |
A corticosteroid, a non-steroidal anti-inflammatory drug and an antihistamine modulate in vivo vascular reactions before and during post-occlusive hyperaemia.
Topics: Adult; Betamethasone Valerate; Blood Flow Velocity; Diphenhydramine; Female; Hemoglobins; Humans; Hy | 1993 |
Prostaglandin inhibition causes an increase in reactive hyperaemia after ischaemic exercise in human forearm.
Topics: Adult; Cyclooxygenase Inhibitors; Forearm; Humans; Hyperemia; Ibuprofen; Indomethacin; Ischemia; Mal | 1999 |
Cigarette smoking, prostaglandins and reactive hyperemia.
Topics: Adult; Female; Forearm; Humans; Hyperemia; Indomethacin; Ischemia; Male; Middle Aged; Prostaglandin | 1979 |
67 other studies available for indomethacin and Active Hyperemia
| Article | Year |
|---|---|
The effect of ageing and indomethacin on forearm reactive hyperaemia in healthy adults.
Topics: Adolescent; Adult; Aged; Aging; Cyclooxygenase Inhibitors; Female; Forearm; Health Status; Humans; H | 2014 |
In vivo regulation of endothelium-dependent vasodilation in the rat renal circulation and the effect of streptozotocin-induced diabetes.
Topics: Acetylcholine; Anesthesia; Animals; Animals, Outbred Strains; Biological Factors; Blood Pressure; Br | 2008 |
Adenosine contributes to blood flow regulation in the exercising human leg by increasing prostaglandin and nitric oxide formation.
Topics: Adenosine; Adult; Analysis of Variance; Cohort Studies; Exercise; Humans; Hyperemia; Indomethacin; L | 2009 |
Suppression of hyperemia and DNA oxidation by indomethacin in cerebral ischemia.
Topics: Animals; Brain Ischemia; Cell Count; Cell Death; DNA; DNA Damage; Gerbillinae; Hyperemia; Indomethac | 2003 |
Role of estrogen in nitric oxide- and prostaglandin-dependent modulation of vascular conductance during treadmill locomotion in rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Estr | 2004 |
Inhibition of nitric oxide and prostaglandins, but not endothelial-derived hyperpolarizing factors, reduces blood flow and aerobic energy turnover in the exercising human leg.
Topics: Adenosine Triphosphate; Adult; Biological Factors; Blood Flow Velocity; Cardiac Output; Cyclooxygena | 2007 |
Effect of indomethacin on cerebral blood flow and development of oxygen convulsions.
Topics: Animals; Cyclooxygenase Inhibitors; Hyperbaric Oxygenation; Hyperemia; Indomethacin; Male; Rats; Rat | 2006 |
Role of Cu,Zn-SOD in the synthesis of endogenous vasodilator hydrogen peroxide during reactive hyperemia in mouse mesenteric microcirculation in vivo.
Topics: Acetylcholine; Animals; Arterioles; Blood Pressure; Carbon Dioxide; Catalase; Cyclic N-Oxides; Cyclo | 2008 |
Test for postischaemic hyperaemia: a means of clinical assessment of microcirculatory reactivity in tissues of patients with liability to seasonal ischaemic noxae.
Topics: Adult; Arthritis; Bronchitis; Female; Humans; Hyperemia; Indomethacin; Iodine; Ischemia; Male; Micro | 1984 |
Arachidonic acid metabolism and regulation of blood flow: effect of indomethacin on cutaneous and subcutaneous reactive hyperaemia in humans.
Topics: Adipose Tissue; Adult; Arachidonic Acids; Blood Circulation; Female; Fingers; Humans; Hyperemia; Ind | 1983 |
Effect of cigarette smoking on reactive hyperaemia in the human finger.
Topics: Adult; Blood Pressure; Female; Fingers; Heart Rate; Humans; Hyperemia; Indomethacin; Male; Middle Ag | 1983 |
Circulating prostanoid levels, both basal and during the chlorpropamide alcohol flush, in non-insulin dependent diabetes.
Topics: 6-Ketoprostaglandin F1 alpha; Alcoholic Beverages; Chlorpropamide; Diabetes Mellitus; Face; Female; | 1981 |
Vascular responses during acute neutrophilic inflammation. Their relationship to in vivo neutrophil emigration.
Topics: Animals; Aspirin; Capillary Permeability; Cell Movement; Chemotactic Factors; Escherichia coli; Hype | 1981 |
Prostaglandin synthesis inhibition and postprandial intestinal hyperemia.
Topics: Animals; Dogs; Feeding Behavior; Female; Hyperemia; Indomethacin; Jejunum; Male; Mefenamic Acid; Pro | 1982 |
The appearance and significance of phospholipase A2 in lymph draining tuberculin reactions.
Topics: Animals; Blood Circulation; Capillary Permeability; Concanavalin A; Female; Hyperemia; Hypersensitiv | 1982 |
Anti-inflammatory effects of betamethasone phosphate, dexamethasone phosphate and indomethacin on rabbit ocular inflammation induced by bovine serum albumin.
Topics: Animals; Aqueous Humor; Betamethasone; Conjunctivitis; Dexamethasone; Disease Models, Animal; Eye; H | 1981 |
Secretion of a hyperemia-inducing moiety by mitogen or glycogen stimulated mononuclear inflammatory cells of sheep and rabbit.
Topics: Animals; Cells, Cultured; Concanavalin A; Culture Media; Dexamethasone; Female; Glycogen; Guinea Pig | 1980 |
Nitric oxide and prostanoids contribute to isoflurane-induced cerebral hyperemia in pigs.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Brain; Carbon Dioxide; Cerebrovascular Circulation; F | 1994 |
Role of endothelial factors in active hyperemic responses in contracting canine muscle.
Topics: Animals; Arginine; Dogs; Endothelium, Vascular; Hindlimb; Hyperemia; Indomethacin; Isometric Contrac | 1995 |
Role of prostaglandins and histamine in hyperemic response to superficial and deep gastric mucosal injury and H+ back-diffusion in cats.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Astemizole; Cats; Dinoprostone; Gastric Acid; Gastric Mucosa; | 1995 |
Nitric oxide is a major mediator in reactive hyperaemia evoked by a brief coronary occlusion in the guinea pig heart.
Topics: Acetylcholine; Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Coronary Vessels; Fema | 1993 |
Effects of antioxidants on the blood-brain barrier and postischemic hyperemia.
Topics: Animals; Antioxidants; Blood Flow Velocity; Blood-Brain Barrier; Brain; Brain Ischemia; Capillary Pe | 1994 |
Interleukin-1 beta enhances capsaicin-induced neurogenic vasodilatation in the rat skin.
Topics: Animals; Blood Pressure; Calcitonin Gene-Related Peptide; Capsaicin; Drug Synergism; Female; Hyperem | 1994 |
The involvement of endothelial dysfunction, nitric oxide and prostanoids in the rat gastric microcirculatory responses to endothelin-1.
Topics: Albumins; Animals; Arginine; Capillary Permeability; Endothelins; Endothelium, Vascular; Gastric Muc | 1994 |
Mechanism of gastric hyperemia induced by intragastric hypertonic saline in rats.
Topics: Analysis of Variance; Animals; Arginine; Blood Pressure; Blood Volume; Dose-Response Relationship, D | 1993 |
Evidence for sensory nerve involvement in cutaneous reactive hyperemia in humans.
Topics: Adult; Anesthesia, Local; Calcitonin Gene-Related Peptide; Capsaicin; Constriction; Humans; Hyperemi | 1993 |
Relationship between opioids and prostaglandins in hypoxia-induced vasodilation of pial arteries in the newborn pig.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Animals, Newborn; Arterioles; Blood Pressure; Carbon Dioxide; | 1996 |
Indomethacin does not alter the effect of pentagastrin on rat gastric defense mechanisms.
Topics: Animals; Cyclooxygenase Inhibitors; Gastric Mucosa; Homeostasis; Hydrogen-Ion Concentration; Hyperem | 1996 |
Role of adenosine and nitric oxide in the hyperemic response to superficial and deep gastric mucosal injury and H+ back-diffusion in cats.
Topics: Adenosine; Animals; Cats; Diffusion; Disease Models, Animal; Gastric Acidity Determination; Gastric | 1996 |
Ischaemic cardiac hyperaemia: role of nitric oxide and other mediators.
Topics: 6-Ketoprostaglandin F1 alpha; Adenosine; Animals; Coronary Circulation; Cyclic GMP; Cyclooxygenase I | 1996 |
Mechanisms mediating gastric hyperemic and acid responses to central TRH analog at a cytoprotective dose.
Topics: Animals; Blood Pressure; Calcitonin Gene-Related Peptide; Capsaicin; Gastric Acid; Gastric Mucosa; H | 1997 |
Types of potassium channels involved in coronary reactive hyperemia depend on duration of preceding ischemia in rat hearts.
Topics: 4-Aminopyridine; Adenosine Diphosphate; Animals; Apamin; Charybdotoxin; Glyburide; Hyperemia; In Vit | 1997 |
Myocardial reactive hyperemia in experimental chronic heart failure: evidence for the role of K+ adenosine triphosphate-dependent channels and cyclooxygenase activity.
Topics: Animals; Cardiac Output, Low; Chronic Disease; Coronary Circulation; Cricetinae; Disease Models, Ani | 1997 |
Influence of venular prostaglandin release on arteriolar diameter during functional hyperemia.
Topics: Animals; Arterioles; Cricetinae; Electric Stimulation; Endothelium, Vascular; Hyperemia; Indomethaci | 1998 |
Tachykinins as enhancers of prostaglandin E2-induced intraocular inflammation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aqueous Humor; Dinoprostone; Dose-Response Relatio | 1998 |
Effects of hydrogen peroxide scavenger Catalase on villous microcirculation in the rat small intestine in a model of inflammatory bowel disease.
Topics: Animals; Blood Flow Velocity; Catalase; Cyclooxygenase Inhibitors; Disease Models, Animal; Drug Eval | 2000 |
Glibenclamide enhances cortical spreading depression-associated hyperemia in the rat.
Topics: Animals; Cerebral Cortex; Charybdotoxin; Cortical Spreading Depression; Glyburide; Hyperemia; Indome | 2000 |
In vivo assessment of villous microcirculation in the rat small intestine in indomethacin-induced inflammation: role of mast-cell stabilizer Ketotifen.
Topics: Animals; Anti-Allergic Agents; Anti-Inflammatory Agents, Non-Steroidal; Arterioles; Blood Flow Veloc | 2000 |
Role of prostaglandins and histamine in reactive hyperemia: in-vivo studies on single mesenteric arterioles.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arteries; Arterioles; Cyclooxygenase Inhibitors; Histamine | 1978 |
Studies on the mechanism of flush induced by nicotinic acid.
Topics: Animals; Aspirin; Cyclic AMP; Cyclooxygenase Inhibitors; Drug Interactions; Ear, External; Female; G | 1977 |
Contribution of prostaglandins to muscle blood flow in anesthetized dogs at rest, during exercise, and following inflow occlusion.
Topics: Animals; Arachidonic Acids; Depression, Chemical; Dogs; Epoprostenol; Hindlimb; Hyperemia; Indometha | 1979 |
Suppressive effects of indomethacin on thermally induced neovascularization of rabbit corneas.
Topics: Animals; Capillaries; Cornea; Eye Burns; Hyperemia; Indomethacin; Prostaglandin Antagonists; Rabbits | 1979 |
Effect of indomethacin on CO2-induced hyperaemia (CO2-response) in the rabbit brain.
Topics: Animals; Carbon Dioxide; Cerebrovascular Circulation; Hyperemia; Indomethacin; Rabbits; Time Factors | 1978 |
Prostaglandin-mediated hyperemia and renin-mediated hypertension during acute ureteral obstruction.
Topics: Acute Disease; Angiotensin II; Animals; Dogs; Female; Hyperemia; Hypertension; Indomethacin; Kidney; | 1978 |
Possible contributions of endogenous prostaglandins to the control of blood pressure.
Topics: Angiotensin II; Animals; Blood Pressure; Bradykinin; Cyclooxygenase Inhibitors; Homeostasis; Hyperem | 1975 |
Regulation of postocclusive hyperemia by endogenously synthesized prostaglandins in the dog heart.
Topics: Adenosine; Animals; Coronary Circulation; Coronary Disease; Coronary Vessels; Cyclooxygenase Inhibit | 1975 |
Prostaglandins and the control of blood flow in the canine myocardium.
Topics: Adenosine; Angiotensin II; Animals; Arachidonic Acids; Blood Pressure; Coronary Circulation; Coronar | 1977 |
Reactive hyperaemia in the dog heart: inter-relations between adenosine, ATP, and aminophylline and the effect of indomethacin.
Topics: Adenosine; Adenosine Triphosphate; Aminophylline; Animals; Coronary Circulation; Dogs; Hyperemia; In | 1977 |
Arteriolar reactive hyperemia: modification by inhibitors of prostaglandin synthesis.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Bradykinin; Hyperemia; Indomethacin; Ischemia; Male; Micro | 1977 |
Failure to abolish reactive hyperemia by indomethacin in denervated kidneys of rabbits.
Topics: Animals; Blood Pressure; Denervation; Hyperemia; Indomethacin; Ischemia; Kidney; Kidney Cortex; Rabb | 1977 |
Endogenous prostaglandins as local regulators of blood flow in man: effect of indomethacin on reactive and functional hyperaemia.
Topics: Forearm; Hyperemia; Indomethacin; Muscles; Prostaglandins E; Regional Blood Flow | 1976 |
Anoxia-induced release of prostaglandins in rabbit isolated hearts.
Topics: Animals; Coronary Circulation; Hyperemia; Hypoxia; Indomethacin; Myocardium; Prostaglandin Antagonis | 1975 |
Ocular compression and noncorticosteroidal anti-inflammatory agents.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Conjunctiva; Eye Diseases; Humans; Hyperemia; Indomethac | 1975 |
Effects of indomethacin on local blood flow regulation in canine heart and kidney.
Topics: Animals; Blood Pressure; Coronary Circulation; Coronary Vessels; Dogs; Electrocardiography; Female; | 1975 |
Participation of endothelium-derived nitric oxide but not prostacyclin in the gastric mucosal hyperaemia due to acid back-diffusion.
Topics: Anesthesia; Animals; Arginine; Blood Pressure; Diffusion; Endothelium, Vascular; Epoprostenol; Femal | 1992 |
[The role of the endothelium in the development of functional hyperemia of the skeletal muscles].
Topics: Animals; Arginine; Dogs; Electric Stimulation; Endothelium, Vascular; Gossypol; Hindlimb; Hyperemia; | 1991 |
Similarities in the pharmacological modulation of reactive hyperemia and vasodilation to hydrogen peroxide in rat skeletal muscle arterioles: effects of probes for endothelium-derived mediators.
Topics: Animals; Arterioles; Drug Interactions; Hydrogen Peroxide; Hyperemia; Indomethacin; Male; Methylene | 1990 |
Role of prostacyclin in the splanchnic hyperemia contributing to portal hypertension.
Topics: Animals; Cyclooxygenase Inhibitors; Epoprostenol; Hyperemia; Hypertension, Portal; Indomethacin; Mal | 1989 |
[Role of the endothelium in the development of reactive hyperemia].
Topics: Animals; Cyclooxygenase Inhibitors; Dogs; Endothelium, Vascular; Femoral Artery; Guanylate Cyclase; | 1989 |
[The role of endothelium in the coronary vessel reactive hyperemia reaction].
Topics: Animals; Blood Circulation; Coronary Vessels; Dogs; Endothelium, Vascular; Hyperemia; Indomethacin; | 1989 |
Indomethacin and ibuprofen enhance anoxia-induced hyperemia in rat brain.
Topics: Animals; Blood Pressure; Cerebrovascular Circulation; Diclofenac; Extracorporeal Circulation; Hypere | 1986 |
Indomethacin and meclofenamate potentiation of skeletal muscle active hyperemia.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Dogs; Hyperemia; Indomethacin; Male; Meclofenamic Acid | 1985 |
Inhibitory effect of quinacrine on myocardial reactive hyperemia in the dog.
Topics: Acetylcholine; Adenosine; Animals; Blood Flow Velocity; Catechols; Coronary Circulation; Dogs; Femal | 1985 |
Effects of indomethacin upon cerebral hemodynamics of newborn pigs.
Topics: Animals; Animals, Newborn; Blood-Brain Barrier; Cerebrovascular Circulation; Hemodynamics; Hypercapn | 1985 |
Inhibition of prostaglandin synthesis and functional hyperaemia in rabbit adipose tissue.
Topics: Adipose Tissue; Adrenocorticotropic Hormone; Animals; Hyperemia; Indomethacin; Prostaglandins; Rabbi | 1972 |
Degeneration release of norepinephrine causes transient ocular hyperemia mediated by prostaglandins.
Topics: Animals; Conjunctiva; Fluorescein Angiography; Hyperemia; Indomethacin; Intraocular Pressure; Iris; | 1973 |
Role of prostaglandins in estrogen-induced uterine hyperemia.
Topics: Animals; Blood Volume; Chromium Radioisotopes; Estradiol; Female; Hyperemia; Indomethacin; Intestine | 1974 |