indomethacin has been researched along with Acquired Immunodeficiency Syndrome in 15 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Acquired Immunodeficiency Syndrome: An acquired defect of cellular immunity associated with infection by the human immunodeficiency virus (HIV), a CD4-positive T-lymphocyte count under 200 cells/microliter or less than 14% of total lymphocytes, and increased susceptibility to opportunistic infections and malignant neoplasms. Clinical manifestations also include emaciation (wasting) and dementia. These elements reflect criteria for AIDS as defined by the CDC in 1993.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We studied the effects of exogenous T cell growth factor (TCGF) (= interleukin-2) and indomethacine on the lymphocyte transformation response in vitro to allogeneic cells, mitogens, and antigens in AIDS patients, those with AIDS-related complex (ARC), and in healthy controls." | 7.67 | Immunological studies in acquired immunodeficiency syndrome: effect of TCGF and indomethacine on the in vitro lymphocyte response. ( Fugger, L; Gaub, J; Gerstoft, J; Hofmann, B; Odum, N; Platz, P; Ryder, LP; Svejgaard, A, 1987) |
| "The effect of indomethacin on mitogen-induced lymphocyte proliferative responses was studied in six normal heterosexual subjects and nine patients with the acquired immune deficiency syndrome (AIDS) and AIDS-related complex (ARC)." | 7.67 | Augmentation of mitogen-induced proliferative responses by in vitro indomethacin in patients with acquired immune deficiency syndrome and AIDS-related complex. ( Ahuja, KK; Grieco, MH; Manvar, D; Moriarty, ML; Reddy, MM, 1985) |
| "Indomethacin is a well tolerated non-steroidal inflammatory drug (NSAID) widely used in the treatment of pericarditis but it can provoke acute renal failure." | 5.40 | Irreversible acute renal failure and cholestatic hepatitis following therapy with indomethacin in an HIV-naive patient with pericarditis: a case report. ( Bonura, S; Colomba, C; Madonia, S; Rubino, R; Siracusa, L, 2014) |
| "The effects of indomethacin and naproxen on zidovudine (ZDV) pharmacokinetics were studied in six patients with the acquired immunodeficiency syndrome (AIDS), AIDS related complex (ARC) or asymptomatic HIV disease using a placebo-controlled crossover design." | 5.07 | The effects of indomethacin and naproxen on zidovudine pharmacokinetics. ( Back, D; Barry, M; Beeching, NJ; Breckenridge, A; Brettle, R; Howe, J; Mitchell, R; Nye, FJ, 1993) |
| "We studied the effects of exogenous T cell growth factor (TCGF) (= interleukin-2) and indomethacine on the lymphocyte transformation response in vitro to allogeneic cells, mitogens, and antigens in AIDS patients, those with AIDS-related complex (ARC), and in healthy controls." | 3.67 | Immunological studies in acquired immunodeficiency syndrome: effect of TCGF and indomethacine on the in vitro lymphocyte response. ( Fugger, L; Gaub, J; Gerstoft, J; Hofmann, B; Odum, N; Platz, P; Ryder, LP; Svejgaard, A, 1987) |
| "The effect of indomethacin on mitogen-induced lymphocyte proliferative responses was studied in six normal heterosexual subjects and nine patients with the acquired immune deficiency syndrome (AIDS) and AIDS-related complex (ARC)." | 3.67 | Augmentation of mitogen-induced proliferative responses by in vitro indomethacin in patients with acquired immune deficiency syndrome and AIDS-related complex. ( Ahuja, KK; Grieco, MH; Manvar, D; Moriarty, ML; Reddy, MM, 1985) |
| "Indomethacin is a well tolerated non-steroidal inflammatory drug (NSAID) widely used in the treatment of pericarditis but it can provoke acute renal failure." | 1.40 | Irreversible acute renal failure and cholestatic hepatitis following therapy with indomethacin in an HIV-naive patient with pericarditis: a case report. ( Bonura, S; Colomba, C; Madonia, S; Rubino, R; Siracusa, L, 2014) |
| "The association of Reiter's Syndrome (RS) with the Acquired Immunodeficiency Syndrome (AIDS) is seldom mentioned in the medical literature." | 1.31 | Reiter's syndrome associated with the Acquired Immunodeficiency Syndrome: a case report. ( Carvalheiro, FA; Malta, JB; Milanelo, D; Silva, MV, 2002) |
| "Twenty-six AIDS patients." | 1.29 | Reduced toxoplasmastatic activity of monocytes and monocyte-derived macrophages from AIDS patients is mediated via prostaglandin E2. ( Delemarre, FG; Kroon, FP; Meenhorst, PL; Stevenhagen, A; van Eer, MY; van Furth, R, 1995) |
| "Patients with the acquired immunodeficiency syndrome (AIDS) are characteristically hypouricemic." | 1.29 | Gouty arthritis in the acquired immunodeficiency syndrome. An unusual but aggressive case. ( Acevedo, M; Cuppari, G; Disla, E; Stein, S, 1995) |
| "In synthesis, it appears that certain AIDS-associated mycoplasma species perturb the function and/or generation of cells from the myelomonocytic lineage via several distinct pathways." | 1.29 | Effects of Mycoplasma fermentans on the myelomonocytic lineage. Different molecular entities with cytokine-inducing and cytocidal potential. ( Castedo, M; Dutilleul, V; Geuskens, M; Kroemer, G; Marchetti, P; Rawadi, G; Roman-Roman, S; Susin, S, 1996) |
| "Sera from homosexual contacts of AIDS patients and from adults with acute cytomegalovirus infection generally lacked this suppressive activity." | 1.27 | Sera from patients with the acquired immunodeficiency syndrome inhibit production of interleukin-2 by normal lymphocytes. ( Djeu, JY; Gelmann, EP; Masur, H; Quinnan, GV; Siegel, JP; Stocks, NI, 1985) |
| "As a group, the patients with KS/AIDS had a significantly depressed response to PHA compared with normal control subjects and patients with hemophilia; this was significantly elevated by indomethacin or by the removal of glass adherent cells." | 1.27 | Abnormal monocyte function in patients with Kaposi's sarcoma. ( Braun, DP; Harris, JE, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (53.33) | 18.7374 |
| 1990's | 4 (26.67) | 18.2507 |
| 2000's | 2 (13.33) | 29.6817 |
| 2010's | 1 (6.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Colomba, C | 1 |
| Siracusa, L | 1 |
| Madonia, S | 1 |
| Bonura, S | 1 |
| Rubino, R | 1 |
| Rivoisy, C | 1 |
| Jauréguiberry, S | 1 |
| M'Bappe, P | 1 |
| Gibeault, M | 1 |
| Bonnard, P | 1 |
| Pialoux, G | 1 |
| Valone, FH | 1 |
| Payan, DG | 1 |
| Abrams, DI | 1 |
| Dohlman, JG | 1 |
| Goetzl, EJ | 1 |
| Palladino, MA | 1 |
| Welte, K | 1 |
| Delemarre, FG | 1 |
| Stevenhagen, A | 1 |
| Kroon, FP | 1 |
| van Eer, MY | 1 |
| Meenhorst, PL | 1 |
| van Furth, R | 1 |
| Disla, E | 1 |
| Stein, S | 1 |
| Acevedo, M | 1 |
| Cuppari, G | 1 |
| Barry, M | 1 |
| Howe, J | 1 |
| Back, D | 1 |
| Breckenridge, A | 1 |
| Brettle, R | 1 |
| Mitchell, R | 1 |
| Beeching, NJ | 1 |
| Nye, FJ | 1 |
| Rawadi, G | 1 |
| Roman-Roman, S | 1 |
| Castedo, M | 1 |
| Dutilleul, V | 1 |
| Susin, S | 1 |
| Marchetti, P | 1 |
| Geuskens, M | 1 |
| Kroemer, G | 1 |
| Malta, JB | 1 |
| Milanelo, D | 1 |
| Carvalheiro, FA | 1 |
| Silva, MV | 1 |
| Salinas Argente, R | 1 |
| Sans-Sabrafen, J | 1 |
| MartÃn, E | 1 |
| Zaragoza, J | 1 |
| Ramirez, J | 1 |
| Alcami, J | 1 |
| Arnaiz-Villena, A | 1 |
| Regueiro, JR | 1 |
| Rioperez, E | 1 |
| Yague, J | 1 |
| Fernandez, F | 1 |
| Siegel, JP | 1 |
| Djeu, JY | 1 |
| Stocks, NI | 1 |
| Masur, H | 1 |
| Gelmann, EP | 1 |
| Quinnan, GV | 1 |
| Braun, DP | 1 |
| Harris, JE | 1 |
| Hofmann, B | 1 |
| Fugger, L | 1 |
| Ryder, LP | 1 |
| Gaub, J | 1 |
| Odum, N | 1 |
| Platz, P | 1 |
| Gerstoft, J | 1 |
| Svejgaard, A | 1 |
| Reddy, MM | 1 |
| Manvar, D | 1 |
| Ahuja, KK | 1 |
| Moriarty, ML | 1 |
| Grieco, MH | 1 |
1 trial available for indomethacin and Acquired Immunodeficiency Syndrome
| Article | Year |
|---|---|
The effects of indomethacin and naproxen on zidovudine pharmacokinetics.
Topics: Acquired Immunodeficiency Syndrome; Adult; Female; Glucuronates; HIV Infections; Humans; Indomethaci | 1993 |
14 other studies available for indomethacin and Acquired Immunodeficiency Syndrome
| Article | Year |
|---|---|
Irreversible acute renal failure and cholestatic hepatitis following therapy with indomethacin in an HIV-naive patient with pericarditis: a case report.
Topics: Acquired Immunodeficiency Syndrome; Acute Kidney Injury; Anti-Inflammatory Agents, Non-Steroidal; An | 2014 |
Tenosynovitis as a possible feature of immune reconstitution syndrome during highly active antiretroviral treatment (HAART).
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Anti-Inflammatory Agents, Non-Steroidal; Antire | 2009 |
Indomethacin enhances the proliferation of mitogen-stimulated T lymphocytes of homosexual males with persistent generalized lymphadenopathy.
Topics: Acquired Immunodeficiency Syndrome; Adult; Dinoprostone; Homosexuality; Humans; In Vitro Techniques; | 1984 |
Interleukin regulation of the immune system (IRIS) in male homosexuals with acquired immune deficiency disease syndrome.
Topics: Acquired Immunodeficiency Syndrome; Adult; Homosexuality; Humans; In Vitro Techniques; Indomethacin; | 1984 |
Reduced toxoplasmastatic activity of monocytes and monocyte-derived macrophages from AIDS patients is mediated via prostaglandin E2.
Topics: Acquired Immunodeficiency Syndrome; Animals; Dinoprostone; Dose-Response Relationship, Drug; Female; | 1995 |
Gouty arthritis in the acquired immunodeficiency syndrome. An unusual but aggressive case.
Topics: Acquired Immunodeficiency Syndrome; Arthritis, Gouty; Biopsy, Needle; Colchicine; Humans; Indomethac | 1995 |
Effects of Mycoplasma fermentans on the myelomonocytic lineage. Different molecular entities with cytokine-inducing and cytocidal potential.
Topics: Acquired Immunodeficiency Syndrome; Apoptosis; Biological Factors; Cell Differentiation; Cyclooxygen | 1996 |
Reiter's syndrome associated with the Acquired Immunodeficiency Syndrome: a case report.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Arthritis, Reactive; Fatal Outcome; Humans; Ind | 2002 |
[Indomethacin as symptomatic medication in patients with advanced HIV infection].
Topics: Acquired Immunodeficiency Syndrome; Adult; Female; Homosexuality; Humans; Indomethacin; Male; Pallia | 1988 |
Indomethacin in the relief of AIDS symptoms.
Topics: Acquired Immunodeficiency Syndrome; Drug Evaluation; Humans; Indomethacin; Infant; Male | 1986 |
Sera from patients with the acquired immunodeficiency syndrome inhibit production of interleukin-2 by normal lymphocytes.
Topics: Acquired Immunodeficiency Syndrome; Cells, Cultured; Cytomegalovirus Infections; Humans; Immune Tole | 1985 |
Abnormal monocyte function in patients with Kaposi's sarcoma.
Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Cells, Cultured; Disease Susceptibility; DNA, | 1986 |
Immunological studies in acquired immunodeficiency syndrome: effect of TCGF and indomethacine on the in vitro lymphocyte response.
Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Complex; Homosexuality; Humans; Indomethacin | 1987 |
Augmentation of mitogen-induced proliferative responses by in vitro indomethacin in patients with acquired immune deficiency syndrome and AIDS-related complex.
Topics: Acquired Immunodeficiency Syndrome; Adjuvants, Immunologic; Adult; Concanavalin A; Humans; In Vitro | 1985 |