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indomethacin and Acquired Immune Deficiency Syndrome

indomethacin has been researched along with Acquired Immune Deficiency Syndrome in 15 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Research Excerpts

ExcerptRelevanceReference
"We studied the effects of exogenous T cell growth factor (TCGF) (= interleukin-2) and indomethacine on the lymphocyte transformation response in vitro to allogeneic cells, mitogens, and antigens in AIDS patients, those with AIDS-related complex (ARC), and in healthy controls."7.67Immunological studies in acquired immunodeficiency syndrome: effect of TCGF and indomethacine on the in vitro lymphocyte response. ( Fugger, L; Gaub, J; Gerstoft, J; Hofmann, B; Odum, N; Platz, P; Ryder, LP; Svejgaard, A, 1987)
"The effect of indomethacin on mitogen-induced lymphocyte proliferative responses was studied in six normal heterosexual subjects and nine patients with the acquired immune deficiency syndrome (AIDS) and AIDS-related complex (ARC)."7.67Augmentation of mitogen-induced proliferative responses by in vitro indomethacin in patients with acquired immune deficiency syndrome and AIDS-related complex. ( Ahuja, KK; Grieco, MH; Manvar, D; Moriarty, ML; Reddy, MM, 1985)
"Indomethacin is a well tolerated non-steroidal inflammatory drug (NSAID) widely used in the treatment of pericarditis but it can provoke acute renal failure."5.40Irreversible acute renal failure and cholestatic hepatitis following therapy with indomethacin in an HIV-naive patient with pericarditis: a case report. ( Bonura, S; Colomba, C; Madonia, S; Rubino, R; Siracusa, L, 2014)
"The effects of indomethacin and naproxen on zidovudine (ZDV) pharmacokinetics were studied in six patients with the acquired immunodeficiency syndrome (AIDS), AIDS related complex (ARC) or asymptomatic HIV disease using a placebo-controlled crossover design."5.07The effects of indomethacin and naproxen on zidovudine pharmacokinetics. ( Back, D; Barry, M; Beeching, NJ; Breckenridge, A; Brettle, R; Howe, J; Mitchell, R; Nye, FJ, 1993)
"We studied the effects of exogenous T cell growth factor (TCGF) (= interleukin-2) and indomethacine on the lymphocyte transformation response in vitro to allogeneic cells, mitogens, and antigens in AIDS patients, those with AIDS-related complex (ARC), and in healthy controls."3.67Immunological studies in acquired immunodeficiency syndrome: effect of TCGF and indomethacine on the in vitro lymphocyte response. ( Fugger, L; Gaub, J; Gerstoft, J; Hofmann, B; Odum, N; Platz, P; Ryder, LP; Svejgaard, A, 1987)
"The effect of indomethacin on mitogen-induced lymphocyte proliferative responses was studied in six normal heterosexual subjects and nine patients with the acquired immune deficiency syndrome (AIDS) and AIDS-related complex (ARC)."3.67Augmentation of mitogen-induced proliferative responses by in vitro indomethacin in patients with acquired immune deficiency syndrome and AIDS-related complex. ( Ahuja, KK; Grieco, MH; Manvar, D; Moriarty, ML; Reddy, MM, 1985)
"Indomethacin is a well tolerated non-steroidal inflammatory drug (NSAID) widely used in the treatment of pericarditis but it can provoke acute renal failure."1.40Irreversible acute renal failure and cholestatic hepatitis following therapy with indomethacin in an HIV-naive patient with pericarditis: a case report. ( Bonura, S; Colomba, C; Madonia, S; Rubino, R; Siracusa, L, 2014)
"The association of Reiter's Syndrome (RS) with the Acquired Immunodeficiency Syndrome (AIDS) is seldom mentioned in the medical literature."1.31Reiter's syndrome associated with the Acquired Immunodeficiency Syndrome: a case report. ( Carvalheiro, FA; Malta, JB; Milanelo, D; Silva, MV, 2002)
"Twenty-six AIDS patients."1.29Reduced toxoplasmastatic activity of monocytes and monocyte-derived macrophages from AIDS patients is mediated via prostaglandin E2. ( Delemarre, FG; Kroon, FP; Meenhorst, PL; Stevenhagen, A; van Eer, MY; van Furth, R, 1995)
"Patients with the acquired immunodeficiency syndrome (AIDS) are characteristically hypouricemic."1.29Gouty arthritis in the acquired immunodeficiency syndrome. An unusual but aggressive case. ( Acevedo, M; Cuppari, G; Disla, E; Stein, S, 1995)
"In synthesis, it appears that certain AIDS-associated mycoplasma species perturb the function and/or generation of cells from the myelomonocytic lineage via several distinct pathways."1.29Effects of Mycoplasma fermentans on the myelomonocytic lineage. Different molecular entities with cytokine-inducing and cytocidal potential. ( Castedo, M; Dutilleul, V; Geuskens, M; Kroemer, G; Marchetti, P; Rawadi, G; Roman-Roman, S; Susin, S, 1996)
"Sera from homosexual contacts of AIDS patients and from adults with acute cytomegalovirus infection generally lacked this suppressive activity."1.27Sera from patients with the acquired immunodeficiency syndrome inhibit production of interleukin-2 by normal lymphocytes. ( Djeu, JY; Gelmann, EP; Masur, H; Quinnan, GV; Siegel, JP; Stocks, NI, 1985)
"As a group, the patients with KS/AIDS had a significantly depressed response to PHA compared with normal control subjects and patients with hemophilia; this was significantly elevated by indomethacin or by the removal of glass adherent cells."1.27Abnormal monocyte function in patients with Kaposi's sarcoma. ( Braun, DP; Harris, JE, 1986)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19908 (53.33)18.7374
1990's4 (26.67)18.2507
2000's2 (13.33)29.6817
2010's1 (6.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Colomba, C1
Siracusa, L1
Madonia, S1
Bonura, S1
Rubino, R1
Rivoisy, C1
Jauréguiberry, S1
M'Bappe, P1
Gibeault, M1
Bonnard, P1
Pialoux, G1
Valone, FH1
Payan, DG1
Abrams, DI1
Dohlman, JG1
Goetzl, EJ1
Palladino, MA1
Welte, K1
Delemarre, FG1
Stevenhagen, A1
Kroon, FP1
van Eer, MY1
Meenhorst, PL1
van Furth, R1
Disla, E1
Stein, S1
Acevedo, M1
Cuppari, G1
Barry, M1
Howe, J1
Back, D1
Breckenridge, A1
Brettle, R1
Mitchell, R1
Beeching, NJ1
Nye, FJ1
Rawadi, G1
Roman-Roman, S1
Castedo, M1
Dutilleul, V1
Susin, S1
Marchetti, P1
Geuskens, M1
Kroemer, G1
Malta, JB1
Milanelo, D1
Carvalheiro, FA1
Silva, MV1
Salinas Argente, R1
Sans-Sabrafen, J1
Martín, E1
Zaragoza, J1
Ramirez, J1
Alcami, J1
Arnaiz-Villena, A1
Regueiro, JR1
Rioperez, E1
Yague, J1
Fernandez, F1
Siegel, JP1
Djeu, JY1
Stocks, NI1
Masur, H1
Gelmann, EP1
Quinnan, GV1
Braun, DP1
Harris, JE1
Hofmann, B1
Fugger, L1
Ryder, LP1
Gaub, J1
Odum, N1
Platz, P1
Gerstoft, J1
Svejgaard, A1
Reddy, MM1
Manvar, D1
Ahuja, KK1
Moriarty, ML1
Grieco, MH1

Trials

1 trial available for indomethacin and Acquired Immune Deficiency Syndrome

ArticleYear
The effects of indomethacin and naproxen on zidovudine pharmacokinetics.
    British journal of clinical pharmacology, 1993, Volume: 36, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Adult; Female; Glucuronates; HIV Infections; Humans; Indomethaci

1993

Other Studies

14 other studies available for indomethacin and Acquired Immune Deficiency Syndrome

ArticleYear
Irreversible acute renal failure and cholestatic hepatitis following therapy with indomethacin in an HIV-naive patient with pericarditis: a case report.
    Le infezioni in medicina, 2014, Volume: 22, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Acute Kidney Injury; Anti-Inflammatory Agents, Non-Steroidal; An

2014
Tenosynovitis as a possible feature of immune reconstitution syndrome during highly active antiretroviral treatment (HAART).
    Joint bone spine, 2009, Volume: 76, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Anti-Inflammatory Agents, Non-Steroidal; Antire

2009
Indomethacin enhances the proliferation of mitogen-stimulated T lymphocytes of homosexual males with persistent generalized lymphadenopathy.
    Journal of clinical immunology, 1984, Volume: 4, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Adult; Dinoprostone; Homosexuality; Humans; In Vitro Techniques;

1984
Interleukin regulation of the immune system (IRIS) in male homosexuals with acquired immune deficiency disease syndrome.
    Annals of the New York Academy of Sciences, 1984, Volume: 437

    Topics: Acquired Immunodeficiency Syndrome; Adult; Homosexuality; Humans; In Vitro Techniques; Indomethacin;

1984
Reduced toxoplasmastatic activity of monocytes and monocyte-derived macrophages from AIDS patients is mediated via prostaglandin E2.
    AIDS (London, England), 1995, Volume: 9, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Animals; Dinoprostone; Dose-Response Relationship, Drug; Female;

1995
Gouty arthritis in the acquired immunodeficiency syndrome. An unusual but aggressive case.
    Arthritis and rheumatism, 1995, Volume: 38, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Arthritis, Gouty; Biopsy, Needle; Colchicine; Humans; Indomethac

1995
Effects of Mycoplasma fermentans on the myelomonocytic lineage. Different molecular entities with cytokine-inducing and cytocidal potential.
    Journal of immunology (Baltimore, Md. : 1950), 1996, Jan-15, Volume: 156, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Apoptosis; Biological Factors; Cell Differentiation; Cyclooxygen

1996
Reiter's syndrome associated with the Acquired Immunodeficiency Syndrome: a case report.
    The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases, 2002, Volume: 6, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Arthritis, Reactive; Fatal Outcome; Humans; Ind

2002
[Indomethacin as symptomatic medication in patients with advanced HIV infection].
    Medicina clinica, 1988, Apr-02, Volume: 90, Issue:13

    Topics: Acquired Immunodeficiency Syndrome; Adult; Female; Homosexuality; Humans; Indomethacin; Male; Pallia

1988
Indomethacin in the relief of AIDS symptoms.
    Lancet (London, England), 1986, Sep-06, Volume: 2, Issue:8506

    Topics: Acquired Immunodeficiency Syndrome; Drug Evaluation; Humans; Indomethacin; Infant; Male

1986
Sera from patients with the acquired immunodeficiency syndrome inhibit production of interleukin-2 by normal lymphocytes.
    The Journal of clinical investigation, 1985, Volume: 75, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Cells, Cultured; Cytomegalovirus Infections; Humans; Immune Tole

1985
Abnormal monocyte function in patients with Kaposi's sarcoma.
    Cancer, 1986, Apr-15, Volume: 57, Issue:8

    Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Cells, Cultured; Disease Susceptibility; DNA,

1986
Immunological studies in acquired immunodeficiency syndrome: effect of TCGF and indomethacine on the in vitro lymphocyte response.
    Cancer detection and prevention. Supplement : official publication of the International Society for Preventive Oncology, Inc, 1987, Volume: 1

    Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Complex; Homosexuality; Humans; Indomethacin

1987
Augmentation of mitogen-induced proliferative responses by in vitro indomethacin in patients with acquired immune deficiency syndrome and AIDS-related complex.
    International journal of immunopharmacology, 1985, Volume: 7, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Adjuvants, Immunologic; Adult; Concanavalin A; Humans; In Vitro

1985