indomethacin has been researched along with Acidosis, Lactic in 3 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Acidosis, Lactic: Acidosis caused by accumulation of lactic acid more rapidly than it can be metabolized. It may occur spontaneously or in association with diseases such as DIABETES MELLITUS; LEUKEMIA; or LIVER FAILURE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pretreatment with indomethacin, or BM 13505, a specific thromboxane A2 receptor blocker, ameliorated the development of metabolic acidosis in N-6 fatty acid-fed animals, demonstrating a role for prostanoids in the sequelae of endotoxemia." | 1.28 | Diets enriched with N-3 fatty acids ameliorate lactic acidosis by improving endotoxin-induced tissue hypoperfusion in guinea pigs. ( Bistrian, BR; Blackburn, GL; Flores, EA; Pomposelli, JJ; Zeisel, SH, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chan, NN | 1 |
| Fauvel, NJ | 1 |
| Feher, MD | 1 |
| Walker, UA | 1 |
| Venhoff, N | 1 |
| Pomposelli, JJ | 1 |
| Flores, EA | 1 |
| Blackburn, GL | 1 |
| Zeisel, SH | 1 |
| Bistrian, BR | 1 |
3 other studies available for indomethacin and Acidosis, Lactic
| Article | Year |
|---|---|
Non-steroidal anti-inflammatory drugs and metformin: a cause for concern?
Topics: Acidosis, Lactic; Acute Kidney Injury; Anti-Inflammatory Agents, Non-Steroidal; Back Pain; Diabetes | 1998 |
Multiple mitochondrial DNA deletions and lactic acidosis in an HIV-infected patient under antiretroviral therapy.
Topics: Acidosis, Lactic; Anti-HIV Agents; Cell Line; DNA, Mitochondrial; Drug Therapy, Combination; Enzyme | 2001 |
Diets enriched with N-3 fatty acids ameliorate lactic acidosis by improving endotoxin-induced tissue hypoperfusion in guinea pigs.
Topics: Acidosis, Lactic; Animals; Dietary Fats; Fatty Acids, Omega-3; Fatty Acids, Unsaturated; Fish Oils; | 1991 |