indomethacin has been researched along with Abnormality, Heart in 35 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
| Excerpt | Relevance | Reference |
|---|---|---|
| " These factors (immaturity, hyperoxia, hypoxia, blood transfusions, intraventricular hemorrhage, apnea, infection, hypercarbia, hypocarbia, patent ductus arteriosus, prostaglandin synthetase inhibitors, vitamin E deficiency, lactic acidosis, prenatal complications, genetic factors) may all be present in an infant." | 4.76 | A reexamination of the role of oxygen in retrolental fibroplasia. ( Dangman, B; Lucey, JF, 1984) |
| "In infants with patent ductus arteriosus, LTV was lower than in controls." | 2.67 | Long-term variability of heart rate increases with successful closure of patent ductus arteriosus in preterm infants. ( Maier, R; Obladen, M; Prietsch, V; Schmitz, L, 1992) |
| "Prenatally diagnosed Ebstein's anomaly with tricuspid valve dysplasia (EA/TVD) is a rare and high-risk congenital heart malformation with limited effective treatments." | 1.72 | Treatment of Severe Fetal Ebstein's Anomaly with Prenatal Nonsteroidal Anti-Inflammatory Therapy. ( Kraus, E; Lannaman, K; Powel, JE; Reddy, C, 2022) |
| " Initial dosing consisted of indomethacin, followed by ibuprofen in most cases." | 1.62 | Effect of In Utero Non-Steroidal Anti-Inflammatory Drug Therapy for Severe Ebstein Anomaly or Tricuspid Valve Dysplasia (NSAID Therapy for Fetal Ebstein anomaly). ( Beroukhim, RS; Cumbermack, KM; Ferrer, Q; Freud, LR; Glickstein, JS; LaFranchi, T; Makhoul, M; Morris, SA; Pedra, SR; Phoon, CK; Sun, HY; Tworetzky, W; Wilkins-Haug, LE, 2021) |
| "Advancements in the medical treatment of congenital heart disease may create less public acclaim than may surgical treatment but many purely medical developments provide the basis for achieving ultimate surgical success and, by judicious use of some forms of medical treatment, operation can be avoided altogether." | 1.27 | Twenty-five years of progress in the medical treatment of pediatric and congenital heart disease. ( McNamara, DG, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (65.71) | 18.7374 |
| 1990's | 5 (14.29) | 18.2507 |
| 2000's | 3 (8.57) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 4 (11.43) | 2.80 |
| Authors | Studies |
|---|---|
| Powel, JE | 1 |
| Kraus, E | 1 |
| Reddy, C | 1 |
| Lannaman, K | 1 |
| Marini, D | 1 |
| Xu, J | 1 |
| Sun, L | 1 |
| Jaeggi, E | 1 |
| Seed, M | 1 |
| Hunter, L | 1 |
| Vigneswaran, TV | 1 |
| Pasupathy, D | 1 |
| Callaghan, N | 1 |
| Tenenbaum, J | 1 |
| Zidere, V | 1 |
| Simpson, JM | 1 |
| Freud, LR | 1 |
| Wilkins-Haug, LE | 1 |
| Beroukhim, RS | 1 |
| LaFranchi, T | 1 |
| Phoon, CK | 1 |
| Glickstein, JS | 1 |
| Cumbermack, KM | 1 |
| Makhoul, M | 1 |
| Morris, SA | 1 |
| Sun, HY | 1 |
| Ferrer, Q | 1 |
| Pedra, SR | 1 |
| Tworetzky, W | 1 |
| Watanabe, K | 1 |
| Tomita, H | 1 |
| Ono, Y | 1 |
| Yamada, O | 1 |
| Kurosaki, K | 1 |
| Echigo, S | 1 |
| Kawata, H | 1 |
| Kishimoto, H | 1 |
| Miura, T | 1 |
| Nakajima, T | 1 |
| Kitajima, H | 1 |
| Distefano, G | 1 |
| McNamara, DG | 1 |
| Drummond, WH | 1 |
| Bucciarelli, RL | 1 |
| Gessner, IH | 1 |
| Gracián Gómez, M | 1 |
| Rodríguez Caamaño, J | 1 |
| Guía Torrent, JM | 1 |
| Lucey, JF | 1 |
| Dangman, B | 1 |
| Olley, PM | 1 |
| Coceani, F | 1 |
| Rowe, RD | 1 |
| Swyer, PR | 1 |
| Strauss, A | 1 |
| Modanlou, HD | 1 |
| Gyepes, M | 1 |
| Wittner, R | 1 |
| Taylor, WJ | 1 |
| Alpert, BS | 1 |
| Heymann, MA | 5 |
| Rudolph, AM | 2 |
| Sharykin, AS | 1 |
| Mogilner, BM | 1 |
| Ashkenazy, M | 1 |
| Borenstein, R | 1 |
| Lancet, M | 1 |
| Clyman, RI | 1 |
| Sabik, JF | 1 |
| Heinemann, MK | 1 |
| Assad, RS | 1 |
| Hanley, FL | 1 |
| Elliott, RB | 1 |
| Starling, MB | 1 |
| Neutze, JM | 1 |
| Levin, DL | 1 |
| Mills, LJ | 1 |
| Weinberg, AG | 1 |
| Gong, G | 1 |
| Prietsch, V | 1 |
| Maier, R | 1 |
| Schmitz, L | 1 |
| Obladen, M | 1 |
| Tulzer, G | 1 |
| Gudmundsson, S | 1 |
| Sharkey, AM | 1 |
| Wood, DC | 1 |
| Cohen, AW | 1 |
| Huhta, JC | 1 |
| Menahem, S | 1 |
| Faist, E | 1 |
| Ertel, W | 1 |
| Salmen, B | 1 |
| Weiler, A | 1 |
| Ressel, C | 1 |
| Bolla, K | 1 |
| Heberer, G | 1 |
| Gittenberger-de Groot, AC | 1 |
| Strengers, JL | 1 |
| Gersony, WM | 1 |
| Maragno, I | 1 |
| Alitto, F | 1 |
| Santostasi, G | 1 |
| Sandri, R | 1 |
| Neri, G | 1 |
| Dorigo, P | 1 |
| Silove, ED | 1 |
| Honda, S | 1 |
| Sandor, GG | 1 |
12 reviews available for indomethacin and Abnormality, Heart
| Article | Year |
|---|---|
Current and future role of fetal cardiovascular MRI in the setting of fetal cardiac interventions.
Topics: Anemia; Anti-Inflammatory Agents, Non-Steroidal; Atrial Septum; Blood Transfusion, Intrauterine; Duc | 2020 |
[The pharmacological manipulation of Botallo's duct in the duct-dependent congenital cardiopathies and in the preterm infants with respiratory distress. A review and personal findings].
Topics: Alprostadil; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Agents; Cerebral Angiography; C | 2005 |
The ductus arteriosus: why and how to manipulate its patency.
Topics: Alprostadil; Ductus Arteriosus, Patent; Gestational Age; Heart Defects, Congenital; Humans; Indometh | 1983 |
[Recent advances and future perspectives in the medical treatment of cardiopathies in children].
Topics: Child; Ductus Arteriosus, Patent; Heart Defects, Congenital; Heart Failure; Humans; Hypoxia; Indomet | 1984 |
A reexamination of the role of oxygen in retrolental fibroplasia.
Topics: Anencephaly; Apnea; Carbon Dioxide; Cerebral Hemorrhage; Ductus Arteriosus, Patent; Exchange Transfu | 1984 |
Neonatal manipulation: patent ductus arteriosus.
Topics: Animals; Aorta, Thoracic; Ductus Arteriosus, Patent; Heart Defects, Congenital; Heart Ventricles; Hu | 1981 |
[Prostaglandins and the treatment of congenital heart defects].
Topics: Ductus Arteriosus, Patent; Heart Defects, Congenital; Humans; Indomethacin; Infant; Infant, Newborn; | 1981 |
Arachidonic acid derivatives in the perinatal period.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Female; Heart Defects, Congenital; Humans; Indomethaci | 1989 |
Prostaglandins and leukotrienes in the perinatal period.
Topics: Ductus Arteriosus; Female; Heart Defects, Congenital; Humans; Indomethacin; Infant, Newborn; Leukotr | 1987 |
Patent ductus arteriosus in the neonate.
Topics: Alprostadil; Blood Circulation; Clinical Trials as Topic; Digoxin; Ductus Arteriosus; Ductus Arterio | 1986 |
[Analogs of prostaglandin-related substances and inhibitors of their formation and metabolism. Clinical application to the pediatric field--arteries and prostaglandins].
Topics: Age Factors; Animals; Ductus Arteriosus, Patent; Heart Defects, Congenital; Humans; Indomethacin; In | 1985 |
Cardiovascular therapy in the newborn.
Topics: Digoxin; Dopamine; Ductus Arteriosus; Ductus Arteriosus, Patent; Heart Defects, Congenital; Humans; | 1985 |
4 trials available for indomethacin and Abnormality, Heart
| Article | Year |
|---|---|
Intravenous indomethacin therapy in infants with a patent ductus arteriosus complicating other congenital heart defects.
Topics: Cardiovascular Agents; Ductus Arteriosus, Patent; Echocardiography; Female; Heart Defects, Congenita | 2003 |
Long-term variability of heart rate increases with successful closure of patent ductus arteriosus in preterm infants.
Topics: Alprostadil; Ductus Arteriosus, Patent; Female; Heart Defects, Congenital; Heart Rate; Humans; Indom | 1992 |
The immune-enhancing effect of perioperative thymopentin administration in elderly patients undergoing major surgery.
Topics: Adjuvants, Immunologic; Aged; Cardiopulmonary Bypass; Clinical Trials as Topic; Drug Hypersensitivit | 1988 |
Patent ductus arteriosus in the neonate.
Topics: Alprostadil; Blood Circulation; Clinical Trials as Topic; Digoxin; Ductus Arteriosus; Ductus Arterio | 1986 |
20 other studies available for indomethacin and Abnormality, Heart
| Article | Year |
|---|---|
Treatment of Severe Fetal Ebstein's Anomaly with Prenatal Nonsteroidal Anti-Inflammatory Therapy.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Ebstein Anomaly; Female; Fetal Diseases; Heart Defects, Con | 2022 |
Effects and side effects of maternal administration of indomethacin for fetal tricuspid valve dysplasia.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Female; Gestational Age; Heart Defects, Congenital; | 2021 |
Effect of In Utero Non-Steroidal Anti-Inflammatory Drug Therapy for Severe Ebstein Anomaly or Tricuspid Valve Dysplasia (NSAID Therapy for Fetal Ebstein anomaly).
Topics: Anti-Inflammatory Agents, Non-Steroidal; Constriction; Ductus Arteriosus; Duration of Therapy; Ebste | 2021 |
Surgical management of congenital cardiac defects in neonates and young infants born with extremely low weight.
Topics: Alprostadil; Cardiac Surgical Procedures; Catecholamines; Ductus Arteriosus, Patent; Heart Defects, | 2003 |
Twenty-five years of progress in the medical treatment of pediatric and congenital heart disease.
Topics: Adrenergic beta-Antagonists; Alprostadil; Cardiac Catheterization; Cardiology; Child; Echocardiograp | 1983 |
Clinical use of prostaglandins and prostaglandin synthetase inhibitors in cardiac problems of the newborn.
Topics: Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Heart Defects, Congenital; Humans; Indomethaci | 1980 |
Congenital heart disease and respiratory distress syndrome. Reversal of indomethacin closure of patent ductus arteriosus by prostaglandin therapy in a preterm infant.
Topics: Alprostadil; Ductus Arteriosus, Patent; Heart Defects, Congenital; Humans; Hypoxia; Indomethacin; In | 1982 |
Prostaglandins and the management of congenital heart disease.
Topics: Age Factors; Alprostadil; Cardiovascular Diseases; Central Nervous System Diseases; Ductus Arteriosu | 1982 |
Hydrops fetalis caused by maternal indomethacin treatment.
Topics: Adult; Diseases in Twins; Edema; Female; Heart Defects, Congenital; Humans; Indomethacin; Infant, Ne | 1982 |
Pharmacology of the ductus arteriosus.
Topics: Animals; Aorta, Thoracic; Cattle; Ductus Arteriosus; Ductus Arteriosus, Patent; Gestational Age; Hea | 1981 |
High-dose steroids prevent placental dysfunction after fetal cardiac bypass.
Topics: Animals; Bicarbonates; Blood Flow Velocity; Carbon Dioxide; Cardiac Output; Cardiopulmonary Bypass; | 1994 |
Medical manipulation of the ductus arteriosus.
Topics: Blood Pressure; Ductus Arteriosus; Ductus Arteriosus, Patent; Heart Defects, Congenital; Humans; Ind | 1975 |
Hemodynamic, pulmonary vascular, and myocardial abnormalities secondary to pharmacologic constriction of the fetal ductus arteriosus. A possible mechanism for persistent pulmonary hypertension and transient tricuspid insufficiency in the newborn infant.
Topics: Animals; Blood Pressure; Blood Vessels; Constriction, Pathologic; Ductus Arteriosus; Fetal Heart; He | 1979 |
Medical treatment of the ductus arteriosus.
Topics: Animals; Aspirin; Coronary Circulation; Ductus Arteriosus; Ductus Arteriosus, Patent; Fetal Heart; F | 1977 |
[The effect of open heart surgery on human cellular immunological function].
Topics: Adolescent; Cardiopulmonary Bypass; Child; Child, Preschool; Heart Defects, Congenital; Humans; Indo | 1992 |
Doppler echocardiography of fetal ductus arteriosus constriction versus increased right ventricular output.
Topics: Blood Flow Velocity; Ductus Arteriosus; Echocardiography, Doppler; Female; Fetal Heart; Gestational | 1991 |
Prostaglandin inhibitors during pregnancy and the effect on the fetus.
Topics: Abnormalities, Drug-Induced; Heart Defects, Congenital; Humans; Indomethacin; Infant, Newborn; Mefen | 1991 |
Histopathology of the arterial duct (ductus arteriosus) with and without treatment with prostaglandin E1.
Topics: Alprostadil; Ductus Arteriosus; Ductus Arteriosus, Patent; Heart Defects, Congenital; Humans; Indome | 1988 |
[Prostaglandins and the perinatal period].
Topics: Blood Pressure; Blood Vessels; Ductus Arteriosus; Ductus Arteriosus, Patent; Fetus; Heart Defects, C | 1987 |
Pharmacological manipulation of the ductus arteriosus.
Topics: Drug Administration Schedule; Ductus Arteriosus; Ductus Arteriosus, Patent; Heart Defects, Congenita | 1986 |