indolepropionic acid has been researched along with Diabetes Mellitus, Type 2 in 7 studies
indolepropionic acid: structure in third source
3-(1H-indol-3-yl)propanoic acid : An indol-3-yl carboxylic acid that is propionic acid substituted by a 1H-indol-3-yl group at position 3.
Diabetes Mellitus, Type 2: A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.
| Excerpt | Relevance | Reference |
|---|---|---|
| " One of the tryptophan derivatives, indolepropionic acid (IPA), is increasingly being studied as a marker for the onset and development of metabolic disorders, including type 2 diabetes (T2D) and non-alcoholic fatty liver disease (NAFLD)." | 9.22 | Indolepropionic Acid, a Gut Bacteria-Produced Tryptophan Metabolite and the Risk of Type 2 Diabetes and Non-Alcoholic Fatty Liver Disease. ( de Mello, VD; Lindström, J; Männistö, V; Pihlajamäki, J; Sehgal, R; Tuomilehto, J; Uusitupa, M, 2022) |
| "Previous studies have indicated that indolepropionic acid (IPA), derived from dietary tryptophan via gut microbiota conversion, is negatively correlated with type 2 diabetes mellitus and systemic low-grade inflammation." | 8.12 | Indolepropionic acid reduces obesity-induced metabolic dysfunction through colonic barrier restoration mediated via tuft cell-derived IL-25. ( Chen, L; Ji, M; Li, C; Li, M; Liu, W; Liu, Y; Pan, C; Sun, S; Xie, Y; Xu, Z; Yang, Y, 2022) |
| " One of the tryptophan derivatives, indolepropionic acid (IPA), is increasingly being studied as a marker for the onset and development of metabolic disorders, including type 2 diabetes (T2D) and non-alcoholic fatty liver disease (NAFLD)." | 5.22 | Indolepropionic Acid, a Gut Bacteria-Produced Tryptophan Metabolite and the Risk of Type 2 Diabetes and Non-Alcoholic Fatty Liver Disease. ( de Mello, VD; Lindström, J; Männistö, V; Pihlajamäki, J; Sehgal, R; Tuomilehto, J; Uusitupa, M, 2022) |
| "Previous studies have indicated that indolepropionic acid (IPA), derived from dietary tryptophan via gut microbiota conversion, is negatively correlated with type 2 diabetes mellitus and systemic low-grade inflammation." | 4.12 | Indolepropionic acid reduces obesity-induced metabolic dysfunction through colonic barrier restoration mediated via tuft cell-derived IL-25. ( Chen, L; Ji, M; Li, C; Li, M; Liu, W; Liu, Y; Pan, C; Sun, S; Xie, Y; Xu, Z; Yang, Y, 2022) |
| "Cognitive decline is one of the complications of type 2 diabetes (T2D)." | 1.56 | Gut microbiota mediates intermittent-fasting alleviation of diabetes-induced cognitive impairment. ( Cadenas, E; Chu, C; Dai, X; Hui, Y; Jin, X; Lan, L; Liu, X; Liu, Z; Pan, J; Ren, B; Shi, L; Shi, R; Tan, X; Wang, D; Wang, J; Wang, L; Wang, Q; Yin, F; Yuan, T; Zhang, H; Zhang, W; Zhao, S; Zhao, T, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 3 (42.86) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, Z | 1 |
| Dai, X | 1 |
| Zhang, H | 1 |
| Shi, R | 1 |
| Hui, Y | 1 |
| Jin, X | 1 |
| Zhang, W | 1 |
| Wang, L | 1 |
| Wang, Q | 1 |
| Wang, D | 1 |
| Wang, J | 2 |
| Tan, X | 1 |
| Ren, B | 1 |
| Liu, X | 2 |
| Zhao, T | 1 |
| Pan, J | 1 |
| Yuan, T | 1 |
| Chu, C | 1 |
| Lan, L | 1 |
| Yin, F | 1 |
| Cadenas, E | 1 |
| Shi, L | 2 |
| Zhao, S | 1 |
| Abildgaard, A | 1 |
| Elfving, B | 1 |
| Hokland, M | 1 |
| Wegener, G | 1 |
| Lund, S | 1 |
| Chen, L | 1 |
| Yang, Y | 1 |
| Sun, S | 1 |
| Xie, Y | 1 |
| Pan, C | 1 |
| Li, M | 1 |
| Li, C | 1 |
| Liu, Y | 1 |
| Xu, Z | 1 |
| Liu, W | 1 |
| Ji, M | 1 |
| Sehgal, R | 1 |
| de Mello, VD | 3 |
| Männistö, V | 1 |
| Lindström, J | 3 |
| Tuomilehto, J | 3 |
| Pihlajamäki, J | 3 |
| Uusitupa, M | 3 |
| Paananen, J | 1 |
| Lankinen, MA | 1 |
| Kuusisto, J | 1 |
| Auriola, S | 2 |
| Lehtonen, M | 2 |
| Rolandsson, O | 1 |
| Bergdahl, IA | 1 |
| Nordin, E | 1 |
| Ilanne-Parikka, P | 1 |
| Keinänen-Kiukaanniemi, S | 1 |
| Landberg, R | 1 |
| Eriksson, JG | 1 |
| Hanhineva, K | 2 |
| Jennis, M | 1 |
| Cavanaugh, CR | 1 |
| Leo, GC | 1 |
| Mabus, JR | 1 |
| Lenhard, J | 1 |
| Hornby, PJ | 1 |
| Tuomainen, M | 1 |
| Peltonen, M | 1 |
1 review available for indolepropionic acid and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
Indolepropionic Acid, a Gut Bacteria-Produced Tryptophan Metabolite and the Risk of Type 2 Diabetes and Non-Alcoholic Fatty Liver Disease.
Topics: Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Bacteria; Diabetes Mellitus, Type 2; Humans; Liver; N | 2022 |
1 trial available for indolepropionic acid and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
Associations of serum indolepropionic acid, a gut microbiota metabolite, with type 2 diabetes and low-grade inflammation in high-risk individuals.
Topics: Blood Glucose; Diabetes Mellitus, Type 2; Fasting; Female; Follow-Up Studies; Humans; Incidence; Ind | 2018 |
5 other studies available for indolepropionic acid and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
Gut microbiota mediates intermittent-fasting alleviation of diabetes-induced cognitive impairment.
Topics: Animals; Brain; Cognition; Cognitive Dysfunction; Computational Biology; Diabetes Mellitus, Experime | 2020 |
The microbial metabolite indole-3-propionic acid improves glucose metabolism in rats, but does not affect behaviour.
Topics: Animals; Anxiety; Behavior, Animal; Blood Glucose; Depression; Diabetes Mellitus, Type 2; Dietary Su | 2018 |
Indolepropionic acid reduces obesity-induced metabolic dysfunction through colonic barrier restoration mediated via tuft cell-derived IL-25.
Topics: Animals; Diabetes Mellitus, Type 2; Diet, High-Fat; Fatty Acids, Nonesterified; Glucose; Indoles; In | 2022 |
Indolepropionic acid and novel lipid metabolites are associated with a lower risk of type 2 diabetes in the Finnish Diabetes Prevention Study.
Topics: Aged; Amino Acids; Bile Acids and Salts; Biomarkers; C-Reactive Protein; Diabetes Mellitus, Type 2; | 2017 |
Microbiota-derived tryptophan indoles increase after gastric bypass surgery and reduce intestinal permeability in vitro and in vivo.
Topics: Animals; Diabetes Mellitus, Type 2; Diet, High-Fat; Epithelial Cells; Gastric Bypass; Gastrointestin | 2018 |